Promoter Hypermethylation Patterns of Death-Associated Protein Kinase and p16 Genes in Vulvar Lichen Sclerosus

No abstract is available for this paper.

• Publication year

  2010

• Venue

  Journal of Lower Genital Tract Disease

• Publication date

  2010-10-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1097/LGT.0b013e3181ec0accPMID 20885153
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Differential hypermethylation of genes in vulvar cancer and lichen sclerosus coexisting or not with vulvar cancer

  2011cited by this paper
• Guidelines for the follow-up of women with vulvar lichen sclerosus in specialist clinics.

  2008cited by this paper
• Review of squamous premalignant vulvar lesions.

  2008influential reference
• CpG Island Hypermethylation of Tumor‐Suppressor Genes in H. pylori‐Infected Non‐Neoplastic Gastric Mucosa Is Linked with Gastric Cancer Risk

  2008cited by this paper
• Decorin and chondroitin sulfate distribution in vulvar lichen sclerosus: correlation with distinct histopathologic stages.

  2007cited by this paper
• Analysis of human papillomavirus and Epstein- Barr virus infection and aberrant death- associated protein kinase methylation in high- grade squamous intraepithelial lesions

  2007cited by this paper
• Aberrant Promoter Methylation Can be Useful as a Marker of Recurrent Disease in Patients with Cervical Intraepithelial Neoplasia Grade III

  2007cited by this paper
• A comparative analysis of lichen sclerosus of the vulva and lichen sclerosus that evolves to vulvar squamous cell carcinoma.

  2007influential reference
• Inactivation of the CDKN2A and the p53 tumour suppressor genes in external genital carcinomas and their precursors

  2007influential reference
• The death-associated protein kinases: structure, function, and beyond.

  2006cited by this paper
• DAPK promotor methylation is an early event in colorectal carcinogenesis.

  2006cited by this paper
• Promoter methylation of p16, DAPK, CDH1, and TIMP‐3 genes in cervical cancer: correlation with clinicopathologic characteristics

  2006cited by this paper
• Methylation‐Associated Silencing of Death‐Associated Protein Kinase Gene in Laryngeal Squamous Cell Cancer

  2005cited by this paper
• Bidirectional signals transduced by DAPK–ERK interaction promote the apoptotic effect of DAPK

  2005cited by this paper
• The hypermethylation and protein expression of p16 INK4A and DNA repair gene O6-methylguanine-DNA methyltransferase in various uterine cervical lesions

  2005cited by this paper
• An overview of lichen sclerosus.

  2005cited by this paper
• Promoter hypermethylation of Death-associated protein-kinase gene associated with advance stage gastric cancer.

  2005cited by this paper
• Aberrant p16 methylation is a biomarker for tobacco exposure in cervical squamous cell carcinogenesis.

  2004cited by this paper
• TP53 mutations in vulval lichen sclerosus adjacent to squamous cell carcinoma of the vulva

  2003influential reference
• Epigenetic down-regulation of death-associated protein kinase in lung cancers.

  2003cited by this paper
• Promoter methylation and down-regulation of DAPK is associated with gastric atrophy.

  2003cited by this paper
• Alterations of the p16/Rb/cyclin-D1 pathway in vulvar carcinoma, vulvar intraepithelial neoplasia, and lichen sclerosus.

  2002influential reference
• Modes of silencing of p16 in development of esophageal squamous cell carcinoma.

  2002cited by this paper
• Germ-line variants in methyl-group metabolism genes and susceptibility to DNA methylation in normal tissues and human primary tumors.

  2002cited by this paper
• Aberrant methylation during cervical carcinogenesis.

  2001cited by this paper
• Promoter hypermethylation patterns of p16, O6-methylguanine-DNA-methyltransferase, and death-associated protein kinase in tumors and saliva of head and neck cancer patients.

  2001cited by this paper
• Death-Associated Protein Kinase-Related Protein 1, a Novel Serine/Threonine Kinase Involved in Apoptosis

  2000cited by this paper
• DNA hypermethylation in tumorigenesis: epigenetics joins genetics.

  2000cited by this paper
• Biomolecular markers as intermediate end points in chemoprevention trials of upper aerodigestive tract cancer

  2000cited by this paper
• Epstein-Barr virus (EBV) genes expression in cervical intraepithelial neoplasia and invasive cervical cancer: a comparative study with human papillomavirus (HPV) infection.

  2000cited by this paper
• p16(INK4a) and the control of cellular proliferative life span.

  1999cited by this paper
• In situ detection of the hypermethylation-induced inactivation of the p16 gene as an early event in oncogenesis.

  1999cited by this paper
• Vulvar intraepithelial neoplasia: age, morphological phenotype, papillomavirus DNA, and coexisting invasive carcinoma.

  1995cited by this paper
• Potential of the in situ polymerase chain reaction in diagnostic cytology.

  1994cited by this paper
• The epithelial changes associated with squamous cell carcinoma of the vulva: a review of the clinical, histological and viral findings in 78 women

  1990cited by this paper
• Temperature-gradient gel electrophoresis. Thermodynamic analysis of nucleic acids and proteins in purified form and in cellular extracts.

  1987influential reference

• Vulvar Lichen Sclerosus from Pathophysiology to Therapeutic Approaches: Evidence and Prospects

  2021cites this paper
• Molecular events in the pathogenesis of vulvar squamous cell carcinoma.

  2020cites this paper
• MALDI Mass Spectrometry Imaging Reveals Decreased CK5 Levels in Vulvar Squamous Cell Carcinomas Compared to the Precursor Lesion Differentiated Vulvar Intraepithelial Neoplasia

  2016cites this paper
• Genetic and epigenetic changes in vulvar squamous cell carcinoma and its precursor lesions: a review of the current literature.

  2015cites this paper
• Altered global methylation and hydroxymethylation status in vulvar lichen sclerosus: further support for epigenetic mechanisms

  2014cites this paper
• Vulvar intraepithelial neoplasia.

  2014cites this paper
• Genetic and epigenetic variation in vulvar cancer: Current research and future clinical practice

  2014cites this paper
• Promoter Hypermethylation of Death-Associated Protein Kinase and p16 Genes in Vulvar Lichen Sclerosus

  2012cites this paper