Protective effects of resveratrol on postmenopausal osteoporosis: regulation of SIRT1-NF-κB signaling pathway.

No abstract is available for this paper.

• Publication year

  2014

• Venue

  Acta Biochimica et Biophysica Sinica

• Publication date

  2014-12-01

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1093/abbs/gmu103PMID 25377437
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Treatment with hydrogen molecules prevents RANKL-induced osteoclast differentiation associated with inhibition of ROS formation and inactivation of MAPK, AKT and NF-kappa B pathways in murine RAW264.7 cells

  2014cited by this paper
• NF‐κB RelB Negatively Regulates Osteoblast Differentiation and Bone Formation

  2014cited by this paper
• Seven sirtuins for seven deadly diseases of aging.

  2013cited by this paper
• Long-term resveratrol treatment prevents ovariectomy-induced osteopenia in rats without hyperplastic effects on the uterus

  2013cited by this paper
• TNF‐α triggers osteogenic differentiation of human dental pulp stem cells via the NF‐κB signalling pathway

  2013cited by this paper
• KMUP-1 Suppresses RANKL-Induced Osteoclastogenesis and Prevents Ovariectomy-Induced Bone Loss: Roles of MAPKs, Akt, NF-κB and Calcium/Calcineurin/NFATc1 Pathways

  2013cited by this paper
• Eldecalcitol for the treatment of osteoporosis

  2013cited by this paper
• Management of metastatic bone disease in the elderly with bisphosphonates and receptor activator of NF-kB ligand inhibitors: effectiveness and safety.

  2013cited by this paper
• The effect of regular physical activity on bone mineral density in post-menopausal women aged 75 and over: a retrospective analysis from the Canadian multicentre osteoporosis study

  2013cited by this paper
• Osteogenic effects of resveratrol in vitro: potential for the prevention and treatment of osteoporosis

  2013cited by this paper
• Effect of methylprednisolone on bone mineral density in rats with ovariectomy-induced bone loss and suppressed endogenous adrenaline levels by metyrosine

  2013cited by this paper
• SIRT1 in Type 2 Diabetes: Mechanisms and Therapeutic Potential

  2013cited by this paper
• SIRT1 as a therapeutic target in inflammaging of the pulmonary disease.

  2012cited by this paper
• Kinsenoside prevents ovariectomy-induced bone loss and suppresses osteoclastogenesis by regulating classical NF-κB pathways

  2012cited by this paper
• Perspectives on translational and therapeutic aspects of SIRT1 in inflammaging and senescence.

  2012cited by this paper
• Denosumab: recent update in postmenopausal osteoporosis.

  2012cited by this paper
• Resveratrol effect on osteogenic differentiation of rat and human adipose derived stem cells in a 3-D culture environment.

  2012cited by this paper
• Resveratrol-mediated SIRT-1 Interactions with p300 Modulate Receptor Activator of NF-κB Ligand (RANKL) Activation of NF-κB Signaling and Inhibit Osteoclastogenesis in Bone-derived Cells

  2011cited by this paper
• Early apoptotic vascular signaling is determined by Sirt1 through nuclear shuttling, forkhead trafficking, bad, and mitochondrial caspase activation.

  2010cited by this paper
• Suppression of NF-kappaB increases bone formation and ameliorates osteopenia in ovariectomized mice.

  2010cited by this paper
• Resveratrol prevents RANKL-induced osteoclast differentiation of murine osteoclast progenitor RAW 264.7 cells through inhibition of ROS production.

  2010cited by this paper
• Bisphosphonates for postmenopausal osteoporosis: Determining duration of treatment

  2009cited by this paper
• Wine, Resveratrol and Health: A Review

  2009cited by this paper
• Smad7 mediates inhibition of Saos2 osteosarcoma cell differentiation by NFkappaB.

  2006cited by this paper
• Smad7 mediates inhibition of Saos2 osteosarcoma cell differentiation by NFκB

  2006cited by this paper
• Effects of Resveratrol on Bone Mineral Density in Ovarectomized Rats

  2005cited by this paper
• Pathogenesis of osteoporosis: concepts, conflicts, and prospects.

  2005cited by this paper
• Examination of the Bone–Implant Interface in Experimentally Induced Osteoporotic Bone

  2004cited by this paper
• Modulation of NF‐κB‐dependent transcription and cell survival by the SIRT1 deacetylase

  2004cited by this paper
• Postmenopausal osteoporosis

  2004cited by this paper
• Prevention and treatment of osteoporosis in postmenopausal women.

  2002cited by this paper
• Malignant reversion of a human osteosarcoma cell line, Saos-2, by inhibition of NFkappaB.

  2002cited by this paper
• Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results From the Women's Health Initiative randomized controlled trial.

  2002cited by this paper
• Resveratrol attenuates ovariectomy-induced hypertension and bone loss in stroke-prone spontaneously hypertensive rats.

  2000cited by this paper
• Assessment of fracture risk and its application to screening for postmenopausal osteoporosis: Synopsis of a WHO report

  1994cited by this paper
• [Postmenopausal osteoporosis].

  1983cited by this paper

• Decoding Epigenetic Switches: How Histone Acetylation/Deacetylation Regulates Mononuclear/Macrophage Fate in Bone Disorders

  2026cites this paper
• Plant-derived food bioactives in bone health: from multi-targeted roles to molecular mechanisms in osteoporosis

  2026cites this paper
• Plant polyphenols delay aging: A review of their anti-aging mechanisms and bioavailability.

  2025cites this paper
• New Perspectives on Postmenopausal Osteoporosis: Mechanisms and Potential Therapeutic Strategies of Sirtuins and Oxidative Stress

  2025cites this paper
• Anti-Osteoporosis and Bone Protective Effects of Resveratrol in Rats With Chronic Kidney Disease-Induced Osteoporosis.

  2025cites this paper
• Aucubin Promotes BMSCs Proliferation and Differentiation of Postmenopausal Osteoporosis Patients by Regulating Ferroptosis and BMP2 Signalling

  2025cites this paper
• The protective role of appendicular lean mass in osteoporosis development among postmenopausal type 2 diabetes patients

  2025cites this paper
• Role of antimicrobial photodynamic therapy (aPDT) and systemic resveratrol on immediate implant placement in type 2 diabetic rats.

  2025cites this paper
• The immune landscape in apical periodontitis: From mechanism to therapy.

  2024cites this paper
• Sirt1: An Increasingly Interesting Molecule with a Potential Role in Bone Metabolism and Osteoporosis

  2024cites this paper
• Bone-targeting engineered milk-derived extracellular vesicles for MRI-assisted therapy of osteoporosis

  2024cites this paper
• Exploring epigenetic strategies for the treatment of osteoporosis

  2024cites this paper
• Prevention and Co-Management of Breast Cancer-Related Osteoporosis Using Resveratrol

  2024cites this paper
• The effects of resveratrol in animal models of primary osteoporosis: a systematic review and meta-analysis

  2024cites this paper
• Mitochondrial dysfunction and therapeutic perspectives in osteoporosis

  2024cites this paper
• Emerging Roles of Natural Compounds in Osteoporosis: Regulation, Molecular Mechanisms and Bone Regeneration

  2024cites this paper
• Unveiling osteoprotective potential of biologically active naringenin in rats with dexamethasone-induced osteoporosis

  2024cites this paper
• Revisiting Resveratrol as an Osteoprotective Agent: Molecular Evidence from In Vivo and In Vitro Studies

  2023cites this paper
• Agomelatine alleviates steroid‐induced osteoporosis by targeting SIRT1/RANKL/FOXO1/OPG signalling in rats

  2023cites this paper
• Long non-coding RNA Homeobox D gene cluster antisense growth-associated long noncoding RNA/microRNA-182-5p/Homeobox protein A10 alleviates postmenopausal osteoporosis via accelerating osteoblast differentiation of bone marrow mesenchymal stem cells

  2023cites this paper
• Safety and Efficacy of Resveratrol in Healing of Maxillofacial Fractures: A Randomized Controlled Study

  2023cites this paper
• Anti-osteoporosis Effect of Cynaropicrin against Ovariectomy-induced Osteoporosis in Rats

  2023cites this paper
• Resveratrol as sensitizer in colorectal cancer plasticity

  2023cites this paper
• Reactive Oxygen Species Control Osteoblast Apoptosis through SIRT1/PGC-1α/P53Lys382 Signaling, Mediating the Onset of Cd-Induced Osteoporosis.

  2023cites this paper
• Resveratrol prevents ovariectomy-induced bone quality deterioration by improving the microarchitectural and biophysicochemical properties of bone

  2023cites this paper
• Effects of resveratrol in an animal model of osteoporosis: a meta-analysis of preclinical evidence

  2023cites this paper
• Protective effect and possible mechanisms of resveratrol in animal models of osteoporosis: A preclinical systematic review and meta‐analysis

  2023influential citation
• Protective effect of vaginal resveratrol administration on joint tissues in ovariectomized rats: Targeting mTOR and сaspase 3.

  2023cites this paper
• Anti-Osteoporotic Mechanisms of Polyphenols Elucidated Based on In Vivo Studies Using Ovariectomized Animals

  2022influential citation
• Anti-osteoporosis Effect of Fisetin against Ovariectomy Induced Osteoporosis in Rats: In silico, in vitro and in vivo Activity.

  2022cites this paper
• Association between NF-κB Signal Pathway-Related Gene Polymorphisms and Response to Alendronate Treatment in Postmenopausal Chinese Women with Low Bone Mineral Density

  2022cites this paper
• Benefits and Implications of Resveratrol Supplementation on Microbiota Modulations: A Systematic Review of the Literature

  2022cites this paper
• A neuronal action of sirtuin 1 suppresses bone mass in young and aging mice

  2022cites this paper
• Age and gender differences in vertebral bone marrow adipose tissue and bone mineral density, based on MRI and quantitative CT.

  2022cites this paper
• The sirtuin family in health and disease

  2022cites this paper
• Resveratrol induces proliferation in preosteoblast cell MC3T3-E1 via GATA-1 activating autophagy.

  2021cites this paper
• A Novel Role of Dapagliflozin in Mitigation of Acetic Acid-Induced Ulcerative Colitis by Modulation of Monocyte Chemoattractant Protein 1 (MCP-1)/Nuclear Factor-Kappa B (NF-κB)/Interleukin-18 (IL-18)

  2021cites this paper
• New Generation of Meso and Antiprogestins (SPRMs) into the Osteoporosis Approach

  2021cites this paper
• Sirtuins as Interesting Players in the Course of HIV Infection and Comorbidities

  2021cites this paper
• Role of sirtuins in bone biology: Potential implications for novel therapeutic strategies for osteoporosis

  2021cites this paper
• SIRT1, a promising regulator of bone homeostasis.

  2021cites this paper
• The Roles of Epigenetics Regulation in Bone Metabolism and Osteoporosis

  2021cites this paper
• Effect of resveratrol and mesenchymal stem cell monotherapy and combined treatment in management of osteoporosis in ovariectomized rats: Role of SIRT1/FOXO3a and Wnt/β-catenin pathways.

  2021cites this paper
• Overexpression of circ_0021739 in Peripheral Blood Mononuclear Cells in Women with Postmenopausal Osteoporosis Is Associated with Reduced Expression of microRNA-194-5p in Osteoclasts

  2021cites this paper
• Use of Network Pharmacology and Molecular Docking Technology to Analyze the Mechanism of Action of Velvet Antler in the Treatment of Postmenopausal Osteoporosis

  2021cites this paper
• Antiosteoporotic effect of hesperidin against ovariectomy‐induced osteoporosis in rats via reduction of oxidative stress and inflammation

  2021cites this paper
• An emerging role of Prevotella histicola on estrogen deficiency-induced bone loss through the gut microbiota-bone axis in postmenopausal women and in ovariectomized mice.

  2021cites this paper
• Effects of resveratrol supplementation on bone quality: a systematic review and meta-analysis of randomized controlled trials

  2021cites this paper
• Use Machine Learning Methods to Explore the Associated Risk Factors of Osteoporosis or Bone Loss in Chinese People with Type 2 Diabetes a Clinical Prediction Model

  2020cites this paper
• Shikonin mitigates ovariectomy-induced bone loss and RANKL-induced osteoclastogenesis via TRAF6-mediated signaling pathways.

  2020cites this paper
• 17β-Estradiol improves osteoblastic cell function through the Sirt1/NF-κB/MMP-8 pathway

  2020cites this paper
• Selective dietary polyphenols induce differentiation of human osteoblasts by adiponectin receptor 1-mediated reprogramming of mitochondrial energy metabolism.

  2020cites this paper
• Resveratrol promotes osteogenesis and alleviates osteoporosis by inhibiting p53

  2020cites this paper
• Potential antiosteoporotic effect of ginkgo biloba extract via regulation of SIRT1-NF-kB signaling pathway

  2020cites this paper
• Medicinal natural products in osteoporosis

  2020cites this paper
• An emerging role of Prevotella histicola on estrogen-deficiency induced bone loss through the gut microbiota-bone axis

  2020cites this paper
• Activation of FoxO1/SIRT1/RANKL/OPG pathway may underlie the therapeutic effects of resveratrol on aging-dependent male osteoporosis

  2020cites this paper
• Betulinic Acid Protects From Bone Loss in Ovariectomized Mice and Suppresses RANKL-Associated Osteoclastogenesis by Inhibiting the MAPK and NFATc1 Pathways

  2020cites this paper
• Role of histone deacetylases in bone development and skeletal disorders.

  2020cites this paper
• Tai Chi on bone mineral density of postmenopausal osteoporosis

  2020cites this paper
• SIRT1/FOXO3a axis plays an important role in the prevention of mandibular bone loss induced by 1,25(OH)2D deficiency

  2020cites this paper
• Tetrandrine Attenuates Cartilage Degeneration, Osteoclast Proliferation, and Macrophage Transformation through Inhibiting P65 Phosphorylation in Ovariectomy-induced Osteoporosis

  2020influential citation
• Dental Pulp Stem Cell Transplantation with 2,3,5,4′‐Tetrahydroxystilbene‐2‐O‐&bgr;‐D‐glucoside Accelerates Alveolar Bone Regeneration in Rats

  2019cites this paper
• Drugs targeting SIRT1, a new generation of therapeutics for osteoporosis and other bone related disorders?

  2019cites this paper
• Up‐regulated CST5 inhibits bone resorption and activation of osteoclasts in rat models of osteoporosis via suppression of the NF‐κB pathway

  2019cites this paper
• Mechanisms of Nontraditional and Lifestyle Interventions for Bone Health

  2019cites this paper
• Increase of Hspa1a and Hspa1b genes in the resting B cells of Sirt1 knockout mice

  2019cites this paper
• Increase of Hspa 1 a and Hspa 1 b genes in the resting B cells of Sirt 1 knockout mice

  2019cites this paper
• Exercise and resveratrol increase fracture resistance in the 3xTg-AD mouse model of Alzheimer’s disease

  2019cites this paper
• Resveratrol counteracts bone loss via mitofilin-mediated osteogenic improvement of mesenchymal stem cells in senescence-accelerated mice

  2018cites this paper
• Nutraceuticals for better management of osteoporosis: An overview

  2018cites this paper
• Decreased microRNA-182-5p helps alendronate promote osteoblast proliferation and differentiation in osteoporosis via the Rap1/MAPK pathway

  2018cites this paper
• Resveratrol restores the level of key inflammatory cytokines and RANKL/OPG ratio in the femur of rat osteoporosis model

  2018cites this paper
• Chikusetsusaponin V Inhibits LPS-Activated Inflammatory Responses via SIRT1/NF-κB Signaling Pathway in RAW264.7 Cells

  2018cites this paper
• Adiponectin signaling and its role in bone metabolism

  2018cites this paper
• Resveratrol reduces senescence‐associated secretory phenotype by SIRT1/NF‐&kgr;B pathway in gut of the annual fish Nothobranchius guentheri

  2018cites this paper
• Beneficial Effects of Concentrated Growth Factors and Resveratrol on Human Osteoblasts In Vitro Treated with Bisphosphonates

  2018cites this paper
• Synergistic Phytochemicals Fail to Protect Against Ovariectomy Induced Bone Loss in Rats

  2018cites this paper
• A Matrine Derivative M54 Suppresses Osteoclastogenesis and Prevents Ovariectomy-Induced Bone Loss by Targeting Ribosomal Protein S5

  2018cites this paper
• Molecular signaling mechanisms behind polyphenol-induced bone anabolism

  2017cites this paper
• Identifying dysregulated pathways in postmenopausal osteoporosis through investigation of crosstalk between pathways.

  2017cites this paper
• Sirtuins as Markers of Bone Disease: A Focus on Osteoarthritis and Osteoporosis

  2016cites this paper
• Identification of crucial genes related to postmenopausal osteoporosis using gene expression profiling

  2016cites this paper
• Osteogenic actions of metoprolol in an ovariectomized rat model of menopause

  2016cites this paper
• Effects of Administration of Amlodipine and Lacidipine on Inflammation-Induced Bone Loss in the Ovariectomized Rat

  2016cites this paper
• Sirtuin1 promotes osteogenic differentiation through downregulation of peroxisome proliferator-activated receptor γ in MC3T3-E1 cells.

  2016cites this paper
• Epigenetic Mechanisms in Bone Biology and Osteoporosis: Can They Drive Therapeutic Choices?

  2016cites this paper
• Appearance of osteoporosis in rat experimental autoimmune encephalomyelitis

  2016cites this paper