The imprecision of heterozygosity‐fitness correlations hinders the detection of inbreeding and inbreeding depression in a threatened species

No abstract is available for this paper.

• Publication year

  2011

• Venue

  Molecular Ecology

• Publication date

  2011-01-01

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1111/j.1365-294X.2010.04930.xPMID 21087447
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Chelex 100 as a medium for simple extraction of DNA for PCR-based typing from forensic material.

  2013cited by this paper
• Perspective: conservation genetics enters the genomics era

  2010cited by this paper
• Simple means to improve the interpretability of regression coefficients

  2010cited by this paper
• Molecular marker‐based pedigrees for animal conservation biologists

  2010cited by this paper
• Inbreeding Depression Accumulation across Life‐History Stages of the Endangered Takahe

  2010influential reference
• The use (or misuse) of microsatellite allelic distances in the context of inbreeding and conservation genetics

  2010cited by this paper
• Do microsatellites reflect genome‐wide genetic diversity in natural populations? A comment on Väli et al. (2008)

  2010cited by this paper
• HETEROZYGOSITY‐FITNESS CORRELATIONS: A TIME FOR REAPPRAISAL

  2010influential reference
• Genome mapping in intensively studied wild vertebrate populations.

  2010cited by this paper
• On the use of large marker panels to estimate inbreeding and relatedness: empirical and simulation studies of a pedigreed zebra finch population typed at 771 SNPs

  2010cited by this paper
• genhet: an easy‐to‐use R function to estimate individual heterozygosity

  2010cited by this paper
• A new test for genotype–fitness associations reveals a single microsatellite allele that strongly predicts the nature of tuberculosis infections in wild boar

  2009cited by this paper
• Pedigrees and microsatellites among endangered ungulates: what do they tell us?

  2009cited by this paper
• HETEROZYGOSITY-FITNESS CORRELATIONS REVEALED BY NEUTRAL AND CANDIDATE GENE MARKERS IN ROE DEER FROM A LONG-TERM STUDY

  2009cited by this paper
• A quantitative review of heterozygosity–fitness correlations in animal populations

  2009influential reference
• MuMIn : multi-model inference, R package version 0.12.0

  2009cited by this paper
• Parentage and Sibship Inference From Multilocus Genotype Data Under Polygamy

  2009cited by this paper
• Genetic diversity of dog breeds: within-breed diversity comparing genealogical and molecular data.

  2009cited by this paper
• Multilocus heterozygosity and inbreeding in the Siberian jay

  2009cited by this paper
• Heterozygosity-fitness correlations within inbreeding classes: local or genome-wide effects?

  2008cited by this paper
• Heterozygosity–fitness correlations and their relevance to studies on inbreeding depression in threatened species

  2008cited by this paper
• Quantifying and managing the loss of genetic variation in a free-ranging population of takahe through the use of pedigrees

  2008influential reference
• genepop’007: a complete re‐implementation of the genepop software for Windows and Linux

  2008cited by this paper
• Isolation and characterization of microsatellite loci from the endangered New Zealand takahe (Gruiformes; Rallidae; Porphyrio hochstetteri)

  2008cited by this paper
• Scaling regression inputs by dividing by two standard deviations

  2008cited by this paper
• Wild pedigrees: the way forward

  2008cited by this paper
• Triadic IBD coefficients and applications to estimating pairwise relatedness.

  2007cited by this paper
• Reliable selfing rate estimates from imperfect population genetic data

  2007cited by this paper
• Multilocus heterozygosity and inbreeding depression in an insular house sparrow metapopulation

  2007cited by this paper
• Effect size, confidence interval and statistical significance: a practical guide for biologists

  2007influential reference
• Towards unbiased parentage assignment: combining genetic, behavioural and spatial data in a Bayesian framework

  2006cited by this paper
• Reduced heterozygosity depresses sperm quality in wild rabbits, Oryctolagus cuniculus.

  2006cited by this paper
• Can a simple algebraic analysis predict markers-genome heterozygosity correlations?

  2006cited by this paper
• What should we weigh to estimate heterozygosity, alleles or loci?

  2006influential reference
• genalex 6: genetic analysis in Excel. Population genetic software for teaching and research

  2006influential reference
• On the estimation of genome-wide heterozygosity using molecular markers.

  2005cited by this paper
• Genetic resistance to bovine tuberculosis in the Iberian wild boar

  2005cited by this paper
• Information theory and hypothesis testing: a call for pluralism

  2005cited by this paper
• Heterozygosity, inbreeding and neonatal traits in Soay sheep on St Kilda

  2005cited by this paper
• A population founded by a single pair of individuals: establishment, expansion, and evolution

  2004cited by this paper
• Does heterozygosity estimate inbreeding in real populations?

  2004influential reference
• Understanding the relationship between the inbreeding coefficient and multilocus heterozygosity: theoretical expectations and empirical data

  2004influential reference
• Measuring inbreeding depression in the wild: the old ways are the best.

  2004influential reference
• Monitoring and managing genetic variation in group breeding populations without individual pedigrees

  2004cited by this paper
• Model selection and multimodel inference : a practical information-theoretic approach

  2003cited by this paper
• Introduction to Conservation Genetics

  2003cited by this paper
• Inbreeding, microsatellite heterozygosity, and morphological traits in Lipizzan horses.

  2003cited by this paper
• Rescue of a severely bottlenecked wolf (Canis lupus) population by a single immigrant

  2003cited by this paper
• Sex‐Specific Consequences of Recent Inbreeding in an Ancestrally Inbred Population of New Zealand Takahe

  2003influential reference
• DNA-based methods for pedigree reconstruction and kinship analysis in natural populations

  2003cited by this paper
• ENVIRONMENTAL CONDITIONS AFFECT THE MAGNITUDE OF INBREEDING DEPRESSION IN SURVIVAL OF DARWIN'S FINCHES

  2002cited by this paper
• Isolation and characterization of microsatellite loci in the globally endangered Corncrake, Crex crex Linné

  2002cited by this paper
• Comparing molecular measures for detecting inbreeding depression

  2002cited by this paper
• On the correlation between heterozygosity and fitness in natural populations

  2002cited by this paper
• Estimating the prevalence of inbreeding from incomplete pedigrees

  2002cited by this paper
• Severe inbreeding depression in collared flycatchers (Ficedula albicollis)

  2002cited by this paper
• Mating system and genetic variation in the endangered New Zealand takahe

  2002influential reference
• The Takahe: Fifty Years of Conservation Management and Research

  2002cited by this paper
• EVALUATION OF d2, A MICROSATELLITE MEASURE OF INBREEDING AND OUTBREEDING, IN WOLVES WITH A KNOWN PEDIGREE

  2001cited by this paper
• The influence of parental relatedness on reproductive success

  2001cited by this paper
• The development of microsatellite loci in the song sparrow, Melospiza melodia (Aves) and genotyping errors associated with good quality DNA

  2001cited by this paper
• EVALUATION OF d 2, A MICROSATELLITE MEASURE OF INBREEDING AND OUTBREEDING, IN WOLVES WITH A KNOWN PEDIGREE

  2001cited by this paper
• Simultaneous inbreeding and outbreeding depression in reintroduced Arabian oryx

  2000cited by this paper
• Sexual selection resulting from extrapair paternity in collared flycatchers.

  1999cited by this paper
• PARASITE‐MEDIATED SELECTION AGAINST INBRED SOAY SHEEP IN A FREE‐LIVING ISLAND POPULATON

  1999cited by this paper
• Statistical confidence for likelihood‐based paternity inference in natural populations

  1998cited by this paper
• Microsatellites reveal heterosis in red deer

  1998cited by this paper
• Microsatellite primers from Geospiza fortis and cross‐species amplification in Darwin's finches

  1998cited by this paper
• Heterozygosity–fitness correlations: new perspectives on old problems

  1998cited by this paper
• INBREEDING AND ITS FITNESS EFFECTS IN AN INSULAR POPULATION OF SONG SPARROWS (MELOSPIZA MELODIA)

  1998cited by this paper
• Estimators for pairwise relatedness and individual inbreeding coefficients

  1996influential reference
• Regression and time series model selection in small samples

  1989cited by this paper
• Loss of Genetic Diversity from Managed Populations: Interacting Effects of Drift, Mutation, Immigration, Selection, and Population Subdivision

  1987cited by this paper

• Estimation of Inbreeding Depression From Overdominant Loci Using Molecular Markers

  2025cites this paper
• Genetics and Analysis of Quantitative Traits

  2025cites this paper
• Inbreeding reduces fitness in spatially structured populations of a threatened rattlesnake

  2025cites this paper
• Long runs of homozygosity are reliable genomic markers of inbreeding depression.

  2025cites this paper
• Ancient mitochondrial genomes unveil the origins and evolutionary history of New Zealand's enigmatic takahē and moho

  2023cites this paper
• The difficulty of detecting inbreeding depression and its effect on conservation decisions.

  2023cites this paper
• Multiple life-stage inbreeding depression impacts demography and extinction risk in an extinct-in-the-wild species

  2021cites this paper
• An evaluation of inbreeding measures using a whole-genome sequenced cattle pedigree

  2020cites this paper
• Studbook and molecular analyses for the endangered black-lion-tamarin; an integrative approach for assessing genetic diversity and driving management in captivity

  2020cites this paper
• On the estimation of inbreeding depression using different measures of inbreeding from molecular markers

  2020cites this paper
• Heterozygosity-fitness correlations in a continental island population of Thorn-tailed Rayadito.

  2020cites this paper
• Comparison of diversity parameters from SNP, microsatellites and pedigree records in the Lidia cattle breed

  2019cites this paper
• Thirty years of conservation genetics in New Zealand: what have we learnt?

  2019cites this paper
• Taxonomy and genetic management of New Zealand's Leiopelma frogs

  2018cites this paper
• Age‐dependent, negative heterozygosity–fitness correlations and local effects in an endangered Caribbean reptile, Iguana delicatissima

  2018cites this paper
• GENOMIC DIVERSITY OF THE CRITICALLY-ENDANGERED ‘ALALĀ (CORVUS HAWAIIENSIS) EARLY AND LATE-BOTTLENECK PRESENTED TO THE FACULTY OF THE TROPICAL CONSERVATION BIOLOGY AND ENVIRONMENTAL SCIENCE PROGRAM IN PARTIAL FULFILEMENT OF THE DEGREE OF MASTERS OF SCIENCE IN TROPICAL BIOLOGY AND ENVIRONMENTAL SCIEN

  2018cites this paper
• A high‐quality pedigree and genetic markers both reveal inbreeding depression for quality but not survival in a cooperative mammal

  2018cites this paper
• Assessing adaptive genetic variation for conservation and management of the European grayling (Thymallus thymallus)

  2017cites this paper
• GENETIC STRUCTURE OF CHINESE CARPS IN PUNJAB AS REVEALED BY DNA MARKERS

  2017cites this paper
• Revisiting Adaptive Potential, Population Size, and Conservation.

  2017cites this paper
• No Compensatory Relationship between the Innate and Adaptive Immune System in Wild-Living European Badgers

  2016cites this paper
• CAPTIVE BREEDING IN ENDANGERED WILDLIFE: A REVIEW

  2016cites this paper
• Genetic Evidence of a Population Bottleneck and Inbreeding in the Endangered New Zealand Sea Lion, Phocarctos hookeri.

  2016cites this paper
• Inbreeding depression across the lifespan in a wild mammal population

  2016cites this paper
• Can multilocus heterozygosity reveal inbreeding depression?

  2016cites this paper
• From the bare minimum: genetics and selection in populations founded by only a few parents

  2016influential citation
• Inbreeding depression by environment interactions in a free-living mammal population

  2016cites this paper
• Valid estimates of individual inbreeding coefficients from marker-based pedigrees are not feasible in wild populations with low allelic diversity

  2015cites this paper
• Direct and indirect causal effects of heterozygosity on fitness-related traits in Alpine ibex

  2015cites this paper
• Context-dependent associations between heterozygosity and immune variation in a wild carnivore

  2015cites this paper
• Toll-like receptor diversity in 10 threatened bird species: relationship with microsatellite heterozygosity

  2015cites this paper
• Local effects drive heterozygosity–fitness correlations in an outcrossing long-lived tree

  2015cites this paper
• GENETIC DIVERSITY AND POPULATION STRUCTURE OF MANDAR BESAR ( Porphyrio porphyrio ) iNHABITING JAVA WETLANDS

  2015influential citation
• Evidence of inbreeding depression in the critically endangered parrot, the kakapo

  2015cites this paper
• Heterozygosity at a single locus explains a large proportion of variation in two fitness‐related traits in great tits: a general or a local effect?

  2014cites this paper
• Survival to metamorphosis is positively related to genetic variability in a critically endangered amphibian species

  2014cites this paper
• Assessment of identity disequilibrium and its relation to empirical heterozygosity fitness correlations: a meta‐analysis

  2014influential citation
• Evaluating the role of inbreeding depression in heterozygosity‐fitness correlations: how useful are tests for identity disequilibrium?

  2014influential citation
• Sex‐Biased Inbreeding Effects on Reproductive Success and Home Range Size of the Critically Endangered Black Rhinoceros

  2014cites this paper
• Pedigree analysis and genetic management of the Kaki

  2014influential citation
• Inbreeding and inbreeding depression in endangered red wolves (Canis rufus)

  2014cites this paper
• Rapid Range Expansion Is Not Restricted by Inbreeding in a Sexually Cannibalistic Spider

  2014cites this paper
• Heterozygosity–fitness correlations in a wild mammal population: accounting for parental and environmental effects

  2014cites this paper
• Testing the effects of genetic crossing distance on embryo survival within a metapopulation of brown trout (Salmo trutta)

  2014cites this paper
• Neighbouring-group composition and within-group relatedness drive extra-group paternity rate in the European badger (Meles meles)

  2014cites this paper
• The genetic basis of fitness: Detecting inbreeding depression and selective sweeps in bighorn sheep

  2013cites this paper
• No correlation between multi‐locus heterozygosity and fitness in the common buzzard despite heterozygote advantage for plumage colour

  2013cites this paper
• Estimating genome-wide heterozygosity: effects of demographic history and marker type

  2013cites this paper
• Reproductive success depends on the quality of helpers in the endangered, cooperative El Oro parakeet (Pyrrhura orcesi)

  2013influential citation
• The role of inbreeding in the reproductive fitness of kakapo (Strigops habroptilus)

  2013influential citation
• Effects of inbreeding on fitness-related traits in a small isolated moose population

  2013influential citation
• Estimating relatedness and inbreeding using molecular markers and pedigrees: the effect of demographic history

  2013cites this paper
• Editorial 2012

  2012cites this paper
• Evidence of inbreeding depression but not inbreeding avoidance in a natural house sparrow population

  2012cites this paper
• Immigration prevents inbreeding in a growing colony of a long‐lived and philopatric seabird

  2012cites this paper
• Variability of individual genetic load: consequences for the detection of inbreeding depression

  2012cites this paper
• A core set of microsatellite markers identified for use in population genetic studies of Purple Swamphen (Porphyrio porphyrio)

  2012cites this paper
• Heterozygosity‐Fitness Correlations and Inbreeding Depression in Two Critically Endangered Mammals

  2012cites this paper
• Inbreeding, body condition, and heterozygosity-fitness correlations in isolated populations of the endangered eastern massasauga rattlesnake (Sistrurus c. catenatus)

  2012influential citation
• Immunity, life history and conservation in the Galapagos sea lion

  2012cites this paper
• Conservation genetic management of a critically endangered New Zealand endemic bird: minimizing inbreeding in the Black Stilt Himantopus novaezelandiae

  2011influential citation
• Heterozygosity is unrelated to adult fitness measures in a large, noninbred population of great tits (Parus major)

  2011influential citation
• Applications and Implications of Neutral versus Non-neutral Markers in Molecular Ecology

  2011cites this paper
• Assessment of genetic variation in the threatened New Zealand sea lion, Phocarctos hookeri, and its association with fitness

  2011cites this paper