Oxytocin receptors: ligand binding, signalling and cholesterol dependence.

No abstract is available for this paper.

• Publication year

  2008

• Venue

  Progress in Brain Research

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1016/S0079-6123(08)00417-2PMID 18655883
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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• The NK1 Receptor Localizes to the Plasma Membrane Microdomains, and Its Activation Is Dependent on Lipid Raft Integrity*

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• Imaging of receptor trafficking by using alpha-bungarotoxin-binding-site-tagged receptors.

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• G-protein coupled receptors in lipid rafts and caveolae: how, when and why do they go there?

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• Real-time detection of interactions between the human oxytocin receptor and G protein-coupled receptor kinase-2.

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• Inhibitory Effect of Barusiban and Atosiban on Oxytocin-Induced Contractions of Myometrium From Preterm and Term Pregnant Women

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• Identification of dimeric and oligomeric complexes of the human oxytocin receptor by co-immunoprecipitation and bioluminescence resonance energy transfer.

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• Oxytocin and vasopressin V1a and V2 receptors form constitutive homo- and heterodimers during biosynthesis.

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• The oxytocin receptor.

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• Identification of an extracellular segment of the oxytocin receptor providing agonist-specific binding epitopes.

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• Human oxytocin receptors in cholesterol-rich vs. cholesterol-poor microdomains of the plasma membrane.

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• Receptor binding of oxytocin and vasopressin antagonists and inhibitory effects on isolated myometrium from preterm and term pregnant women

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• Activation mechanism of human oxytocin receptor: a combined study of experimental and computer-simulated mutagenesis.

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• Membrane cholesterol modulates galanin-GalR2 interaction.

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• The proximal portion of the COOH terminus of the oxytocin receptor is required for coupling to g(q), but not g(i). Independent mechanisms for elevating intracellular calcium concentrations from intracellular stores.

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• A serine cluster prevents recycling of the V2 vasopressin receptor.

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• Oxytocin receptor binding and uterotonic activity of carbetocin and its metabolites following enzymatic degradation.

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• Cholesterol as modulator of receptor function.

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• Coupling of oxytocin receptor to G proteins in rat myometrium during labor: Gi receptor interaction.

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• The role of N-terminal glycosylation in the human oxytocin receptor.

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• Separate Agonist and Peptide Antagonist Binding Sites of the Oxytocin Receptor Defined by Their Transfer into the V2 Vasopressin Receptor*

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• Oxytocin is required for nursing but is not essential for parturition or reproductive behavior.

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• Alteration of the myometrial plasma membrane cholesterol content with beta-cyclodextrin modulates the binding affinity of the oxytocin receptor.

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• Advances in the design of selective antagonists, potential tocolytics, and radioiodinated ligands for oxytocin receptors.

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