MAPT haplotype H1G is associated with increased risk of dementia with Lewy bodies

No abstract is available for this paper.

• Publication year

  2016

• Venue

  Alzheimer's & Dementia

• Publication date

  2016-12-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1016/j.jalz.2016.05.002PMID 27287057PMCID PMC5143206
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Genome-wide association study of corticobasal degeneration identifies risk variants shared with progressive supranuclear palsy

  2015cited by this paper
• Role for the microtubule-associated protein tau variant p.A152T in risk of α-synucleinopathies

  2015cited by this paper
• A NOVEL ALZHEIMER DISEASE LOCUS LOCATED NEAR THE GENE ENCODING TAU PROTEIN

  2015cited by this paper
• Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson’s disease

  2014cited by this paper
• Association of MAPT haplotypes with Alzheimer’s disease risk and MAPT brain gene expression levels

  2014influential reference
• Genetic analysis implicates APOE, SNCA and suggests lysosomal dysfunction in the etiology of dementia with Lewy bodies

  2014influential reference
• Differential clinicopathologic and genetic features of late-onset amnestic dementias

  2014cited by this paper
• Alpha-synuclein and tau: teammates in neurodegeneration?

  2014cited by this paper
• Apolipoprotein E ε2 genotype delays onset of dementia with Lewy bodies in a Norwegian cohort

  2014cited by this paper
• MAPT H1 haplotype is associated with enhanced α-synuclein deposition in dementia with Lewy bodies.

  2013cited by this paper
• Investigating the role of FUS exonic variants in essential tremor.

  2013cited by this paper
• A multicenter study of glucocerebrosidase mutations in dementia with Lewy bodies.

  2013cited by this paper
• Incidence of dementia with Lewy bodies and Parkinson disease dementia.

  2013cited by this paper
• Variation in tau isoform expression in different brain regions and disease states.

  2013cited by this paper
• DLB and PDD: a role for mutations in dementia and Parkinson disease genes?

  2012cited by this paper
• Common inversion polymorphism at 17q21.31 affects expression of multiple genes in tissue-specific manner

  2012cited by this paper
• GBA mutations increase risk for Lewy body disease with and without Alzheimer disease pathology

  2012cited by this paper
• Apolipoprotein E4 Frequencies in a Japanese Population with Alzheimer's Disease and Dementia with Lewy Bodies

  2011cited by this paper
• Dementia risk in Parkinson disease: disentangling the role of MAPT haplotypes.

  2011cited by this paper
• Different MAPT haplotypes are associated with Parkinson's disease and progressive supranuclear palsy.

  2011cited by this paper
• Identification of common variants influencing risk of the tauopathy Progressive Supranuclear Palsy

  2011influential reference
• Association of glucocerebrosidase mutations with dementia with lewy bodies.

  2009cited by this paper
• Genome-Wide Association Study reveals genetic risk underlying Parkinson’s disease

  2009cited by this paper
• The MAPT H1c risk haplotype is associated with increased expression of tau and especially of 4 repeat containing transcripts.

  2007cited by this paper
• Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB): Report of the Consortium on DLB International Workshop

  2006cited by this paper
• A common inversion under selection in Europeans

  2005cited by this paper
• Linkage disequilibrium fine mapping and haplotype association analysis of the tau gene in progressive supranuclear palsy and corticobasal degeneration

  2005influential reference
• Diagnosis and management of dementia with Lewy bodies

  2005cited by this paper
• The H1c haplotype at the MAPT locus is associated with Alzheimer's disease.

  2005cited by this paper
• Estimation and Tests of Haplotype-Environment Interaction when Linkage Phase Is Ambiguous

  2003cited by this paper
• Is Dementia with Lewy Bodies the Second Most Common Cause of Dementia?

  2002cited by this paper
• Score tests for association between traits and haplotypes when linkage phase is ambiguous.

  2002cited by this paper
• [Apolipoprotein E4 and Alzheimer's disease].

  2001cited by this paper
• Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB)

  1996cited by this paper
• Apolipoprotein E4 and Alzheimer's disease pathology in Lewy body disease and in other beta-amyloid-forming diseases.

  1994cited by this paper
• Apolipoprotein E4 and Alzheimer's disease pathology in Lewy body disease and in other β-amyloid-forming diseases

  1994cited by this paper
• Senile dementia of the Lewy body type has an apolipoprotein E epsilon 4 allele frequency intermediate between controls and Alzheimer's disease.

  1994cited by this paper

• Shared genetic architecture of psychiatric disorders and ocular diseases: Evidence from genome-wide analyses

  2026cites this paper
• Heritability and shared environmental effects of brain diseases in 12,040 extended families

  2025cites this paper
• A structural haplotype in the 17q21.31 MAPT region is associated with increased risk for chronic traumatic encephalopathy endophenotypes

  2025cites this paper
• Chr:17q21.31 locus risk haplotype H1 susceptibility to ferroptosis is mediated by endolysosomal pathway

  2025cites this paper
• Exploring MAPT-containing H1 and H2 haplotypes in Parkinson’s disease across diverse populations

  2025cites this paper
• APOE4 genotype and MAPT haplotype modify repetitive head impact biomarkers in retired professional fighters

  2025cites this paper
• Neuropathology of Lewy body dementia: Lewy-related pathology, α-synuclein oligomers, and comorbid pathologies

  2025cites this paper
• Dementia with Lewy Bodies: Genomics, Transcriptomics, and Its Future with Data Science

  2024cites this paper
• CNV-Finder: Streamlining Copy Number Variation Discovery

  2024cites this paper
• The genetic basis of multiple system atrophy

  2023cites this paper
• Total recall: the role of PIDDosome components in neurodegeneration.

  2023cites this paper
• Elucidating distinct molecular signatures of Lewy body dementias.

  2023cites this paper
• Association between the LRP1B and APOE loci and the development of Parkinson’s disease dementia

  2022cites this paper
• Retrotransposon insertions associated with risk of neurologic and psychiatric diseases

  2022cites this paper
• Mitochondrial genomic variation in dementia with Lewy bodies: association with disease risk and neuropathological measures

  2022cites this paper
• Pinpointing novel risk loci for Lewy body dementia and the shared genetic etiology with Alzheimer’s disease and Parkinson’s disease: a large-scale multi-trait association analysis

  2022cites this paper
• Parkinson's disease

  2021cites this paper
• Tau and MAPT genetics in tauopathies and synucleinopathies.

  2021cites this paper
• Genetic Architecture and Molecular, Imaging and Prodromic Markers in Dementia with Lewy Bodies: State of the Art, Opportunities and Challenges

  2021cites this paper
• Association of MAPT subhaplotypes with clinical and demographic features in Parkinson’s disease

  2020cites this paper
• Pathological Influences on Clinical Heterogeneity in Lewy Body Diseases

  2020cites this paper
• Systematic review of genetic association studies in people with Lewy body dementia

  2020cites this paper
• Epigenetic Regulation in the pathophysiology of Lewy Body Dementia.

  2020cites this paper
• MAPT subhaplotypes in corticobasal degeneration: assessing associations with disease risk, severity of tau pathology, and clinical features

  2020cites this paper
• Title: Systematic review of genetic association studies in people with Lewy body dementia Short running title: Genetics of Lewy body dementia

  2020cites this paper
• Genetics of REM Sleep Behavior Disorder

  2019cites this paper
• A comprehensive screening of copy number variability in dementia with Lewy bodies.

  2019cites this paper
• Parkinson's Disease Dementia and Lewy Body Disease

  2019cites this paper
• Association of MAPT Subhaplotypes With Risk of Progressive Supranuclear Palsy and Severity of Tau Pathology.

  2019cites this paper
• Association of MAPT H1 subhaplotypes with neuropathology of lewy body disease

  2019cites this paper
• Dementia with Lewy bodies: an update and outlook

  2019cites this paper
• A soluble tau fragment generated by caspase-2 is associated with dementia in Lewy body disease

  2019cites this paper
• Investigating the genetic architecture of dementia with Lewy bodies: a two-stage genome-wide association study.

  2018cites this paper
• Dementia with Lewy bodies and Parkinson’s disease-dementia: current concepts and controversies

  2018cites this paper
• Are dementia with Lewy bodies and Parkinson’s disease dementia the same disease?

  2018cites this paper
• Investigating the genetic architecture of Dementia with Lewy bodies: a genome-wide association study

  2018cites this paper
• Synaptogyrin-3 Mediates Presynaptic Dysfunction Induced by Tau.

  2018cites this paper
• Living with Lewy body dementia. Treatment, survival & quality of life.

  2018cites this paper
• Cognitive and Pathological Influences of Tau Pathology in Lewy Body Disorders

  2018cites this paper
• The Contribution of Tau, Amyloid-Beta and Alpha-Synuclein Pathology to Dementia in Lewy Body Disorders

  2018cites this paper
• The Genetics of Dementia with Lewy Bodies: Current Understanding and Future Directions

  2018cites this paper
• Full sequencing and haplotype analysis of MAPT in Parkinson's disease and rapid eye movement sleep behavior disorder

  2018cites this paper
• An update on the genetics of dementia with Lewy bodies.

  2017cites this paper