AMPA‐mediated excitotoxicity in oligodendrocytes: role for Na+–K+–Cl− co‐transport and reversal of Na+/Ca2+ exchanger

No abstract is available for this paper.

• Publication year

  2007

• Venue

  Journal of Neurochemistry

• Publication date

  2007-09-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1111/j.1471-4159.2007.04638.xPMID 17490438
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2006influential reference
• General mechanisms of axonal damage and its prevention.

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• NMDA receptors are expressed in developing oligodendrocyte processes and mediate injury

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• Pharmacology of Brain Na+/Ca2+ Exchanger: From Molecular Biology to Therapeutic Perspectives

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  2000influential reference
• Rapid Ischemic Cell Death in Immature Oligodendrocytes: A Fatal Glutamate Release Feedback Loop

  2000cited by this paper
• Sodium-potassium-chloride cotransport.

  2000cited by this paper
• Na+-K+-2Cl- cotransporter in immature cortical neurons: A role in intracellular Cl- regulation.

  1999cited by this paper
• Sodium/calcium exchange: its physiological implications.

  1999cited by this paper
• Expression of the Na(+)-K(+)-2Cl- cotransporter BSC2 in the nervous system.

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  1997influential reference
• Tissue specificity and alternative splicing of the Na+/Ca2+ exchanger isoforms NCX1, NCX2, and NCX3 in rat.

  1997cited by this paper
• Role of NMDA and Non-NMDA Ionotropic Glutamate Receptors in Traumatic Spinal Cord Axonal Injury

  1997cited by this paper
• Pathophysiology of oligodendroglial excitotoxicity

  1996cited by this paper
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  1995cited by this paper
• Cloned glutamate receptors.

  1994cited by this paper
• Chloride transport blockers prevent N-methyl-D-aspartate receptor-channel complex activation.

  1992cited by this paper
• Role of Na/K/Cl cotransport in astrocytes.

  1992cited by this paper
• Identification of a site in glutamate receptor subunits that controls calcium permeability

  1991cited by this paper
• A new generation of Ca2+ indicators with greatly improved fluorescence properties.

  1985cited by this paper
• Pharmacology of the brain.

  1967cited by this paper

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  2022cites this paper
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  2022cites this paper
• GluA2 overexpression in oligodendrocyte progenitors promotes postinjury oligodendrocyte regeneration

  2021cites this paper
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  2021cites this paper
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  2020cites this paper
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