A phase I multicenter study of antroquinonol in patients with metastatic non-small-cell lung cancer who have received at least two prior systemic treatment regimens, including one platinum-based chemotherapy regimen.

No abstract is available for this paper.

• Publication year

  2015

• Venue

  Molecular and clinical oncology

• Publication date

  2015-11-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.3892/MCO.2015.642PMID 26807250PMCID PMC4665158
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Antroquinonol, a natural ubiquinone derivative, induces a cross talk between apoptosis, autophagy and senescence in human pancreatic carcinoma cells.

  2012cited by this paper
• Antroquinonol inhibits NSCLC proliferation by altering PI3K/mTOR proteins and miRNA expression profiles.

  2011cited by this paper
• An Extract of Antrodia camphorata Mycelia Attenuates the Progression of Nephritis in Systemic Lupus Erythematosus-Prone NZB/W F1 Mice

  2011cited by this paper
• A Preclinical Evaluation of Antrodia camphorata Alcohol Extracts in the Treatment of Non-Small Cell Lung Cancer Using Non-Invasive Molecular Imaging

  2011cited by this paper
• Antroquinonol displays anticancer potential against human hepatocellular carcinoma cells: a crucial role of AMPK and mTOR pathways.

  2010cited by this paper
• New response evaluation criteria in solid tumours: revised RECIST guideline (version 1.1).

  2009cited by this paper
• [New response evaluation criteria in solid tumours-revised RECIST guideline (version 1.1)].

  2009influential reference
• A New Cytotoxic Agent from Solid-State Fermented Mycelium of Antrodia camphorata

  2007cited by this paper
• Neuroprotective diterpenes from the fruiting body of Antrodia camphorata.

  2006cited by this paper
• American Society of Clinical Oncology treatment of unresectable non-small-cell lung cancer guideline: update 2003.

  2004cited by this paper
• Protective effects of fermented filtrate from Antrodia camphorata in submerged culture against CCl4-induced hepatic toxicity in rats.

  2003cited by this paper
• Protection of oxidative damage by aqueous extract from Antrodia camphorata mycelia in normal human erythrocytes.

  2002cited by this paper

• The Inclusion of Dietary and Medicinal Mushrooms into Translational Oncology: Pros and Cons at the Molecular Level

  2026cites this paper
• Current and further outlook on the protective potential of Antrodia camphorata against neurological disorders

  2024cites this paper
• Antrodia salmonea suppresses epithelial-mesenchymal transition/metastasis and Warburg effects by inhibiting Twist and HIF-1α expression in Twist-overexpressing head and neck squamous cell carcinoma cells.

  2023cites this paper
• In vitro and in vivo anti-tumor activity of Antrodia salmonea against twist-overexpressing HNSCC cells: Induction of ROS-mediated autophagic and apoptotic cell death.

  2022cites this paper
• Enhancement of antroquinonol production via the overexpression of 4-hydroxybenzoate polyprenyltransferase biosynthesis-related genes in Antrodia cinnamomea.

  2021cites this paper
• Terpenoids from the medicinal mushroom Antrodia camphorata: chemistry and medicinal potential.

  2020cites this paper
• An increase in cell membrane permeability in the in situ extractive fermentation improves the production of antroquinonol from Antrodia camphorata S-29

  2020cites this paper
• Role of coenzymes in cancer metabolism.

  2020cites this paper
• 12-25-2018 Targeted Therapies for Advanced Non-Small Cell Lung Cancer

  2019cites this paper
• Pharmacological activities of antroquinonol- Mini review.

  2019cites this paper
• Diversity of potentially exploitable pharmacological activities of the highly prized edible medicinal fungus Antrodia camphorata

  2019cites this paper
• Renoprotective Effects of Antroquinonol in Rats with Nω-Nitro-l-Arginine Methyl Ester-Induced Hypertension

  2018cites this paper
• Hypermethylation of CCND2 in Lung and Breast Cancer Is a Potential Biomarker and Drug Target

  2018cites this paper
• Targeted therapies for advanced non-small cell lung cancer

  2018cites this paper
• Antroquinonol, a Ubiquinone Derivative from the Mushroom Antrodia camphorata, Inhibits Colon Cancer Stem Cell-like Properties: Insights into the Molecular Mechanism and Inhibitory Targets.

  2017cites this paper
• Current Advances on the Structure, Bioactivity, Synthesis, and Metabolic Regulation of Novel Ubiquinone Derivatives in the Edible and Medicinal Mushroom Antrodia cinnamomea.

  2017cites this paper
• Correction: Molecular Heterogeneity of Ewing Sarcoma as Detected by Ion Torrent Sequencing

  2016cites this paper
• Genotoxicity, Acute and Sub-Chronic Toxicity Studies of Solid-State Cultivated Mycelial Powder of Antrodia cinnamomea

  2016cites this paper
• Molecular Heterogeneity of Ewing Sarcoma as Detected by Ion Torrent Sequencing

  2016cites this paper