32P-postlabeling of a DNA adduct derived from 4,4'-methylenedianiline, in the olfactory epithelium of rats exposed by inhalation to 4,4'-methylenediphenyl diisocyanate.

No abstract is available for this paper.

• Publication year

  1996

• Venue

  Carcinogenesis

• Publication date

  1996-05-01

• Fields of study

  Medicine, Chemistry, Environmental Science

• Identifiers
  DOI 10.1093/CARCIN/17.5.1069PMID 8640915
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Formation and removal of DNA adducts in Fischer-344 rats exposed to 2,4-diaminotoluene

  2009cited by this paper
• Comparative Pulmonary Toxicities and Carcinogenicities of Chronically Inhaled Diesel Exhaust and Carbon Black in F344 Rats

  1995cited by this paper
• Hemoglobin adducts and urine metabolites of 4,4'-methylenedianiline after 4,4'-methylenediphenyl diisocyanate exposure of rats.

  1995cited by this paper
• 32P-postlabeling analysis of DNA adducts formed in vitro and in rat skin by methylenediphenyl-4,4'-diisocyanate (MDI).

  1995cited by this paper
• Comparative Pulmonary Toxicities and Carcinogenicities of Chronically Inhaled Diesel Exhaust and Carban Black in F344 Rats

  1995cited by this paper
• Formation and Removal of DNA Adducts in the Liver of Rats Chronically Fed the Food‐borne Carcinogen, 2‐Amino‐3,8‐dimethylimidazo[4,5‐f]quinoxaline

  1995cited by this paper
• Chronic inhalation toxicity and carcinogenicity study of respirable polymeric methylene diphenyl diisocyanate (polymeric MDI) aerosol in rats.

  1994cited by this paper
• Evidence supporting the role of DNA pyridyloxobutylation in rat nasal carcinogenesis by tobacco-specific nitrosamines.

  1994cited by this paper
• DNA adducts of carcinogenic aromatic amines.

  1994cited by this paper
• Tobacco-specific nitrosamine adducts: studies in laboratory animals and humans.

  1993cited by this paper
• Hypersensitivity pneumonitis-like reaction among workers exposed to diphenylmethane [correction to piphenylmethane] diisocyanate (MDI).

  1993cited by this paper
• Cytotoxicity and DNA-protein crosslink formation in rat nasal tissues exposed to vinyl acetate are carboxylesterase-mediated.

  1993cited by this paper
• The low prevalence of occupational asthma and antibody-dependent sensitization to diphenylmethane diisocyanate in a plant engineered for minimal exposure to diisocyanates.

  1993cited by this paper
• Hypersensitivity pneumonitis-like reaction among workers exposed to piphenylmethane diisocyanate (MDI)

  1993cited by this paper
• CHAPTER 2 – XENOBIOTIC METABOLISM BY ISOLATED PULMONARY BRONCHIOLAR AND ALVEOLAR CELLS

  1993cited by this paper
• Human biomonitoring and the 32P-postlabeling assay.

  1992cited by this paper
• Normal histology of the nasal cavity and application of special techniques.

  1990cited by this paper
• Regional Deposition of Inhaled Monodisperse Coarse and Fine Aerosol Particles in Small Laboratory Animals

  1988cited by this paper
• Occupational medicine: principles and practical applications.

  1988cited by this paper
• Distribution of DNA adducts in the respiratory tract of rats exposed to diesel exhaust.

  1988cited by this paper
• Salmonella mutagenicity tests: III. Results from the testing of 255 chemicals.

  1987cited by this paper
• Molecular dosimetry of DNA adduct formation and cell toxicity in rat nasal mucosa following exposure to the tobacco specific nitrosamine 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone and their relationship to induction of neoplasia.

  1987cited by this paper
• 4,4'-Methylenedianiline and its dihydrochloride.

  1986cited by this paper
• Respiratory effects of inhaled isocyanates.

  1986cited by this paper
• The results of microbial mutation test for forty-three industrial chemicals.

  1985cited by this paper
• Enhanced sensitivity of 32P-postlabeling analysis of aromatic carcinogen:DNA adducts.

  1985cited by this paper
• The relevance of covalent binding to mouse liver DNA to the carcinogenic action of hexachlorocyclohexane isomers.

  1983cited by this paper
• Comparative morphometry of the nasal cavity in rats and mice.

  1982cited by this paper
• Mutagenic action of isocyanates used in the production of polyurethanes.

  1980cited by this paper

• Review of theOccupational MechanismsExposure to Isocyanates : of Action

  2018cites this paper
• Assessment of dermal uptake of diphenylmethane-4,4’-diisocyanate using tape stripping and biological monitoring

  2018cites this paper
• Synthesis of minoxidil conjugates and their evaluation as HL-60 differentiation agents.

  2016cites this paper
• Determination of albumin adducts of 4,4′-methylenediphenyl diisocyanate in workers of a 4,4′-methylenedianiline factory

  2016cites this paper
• Methylene Diphenyl Diisocyanate Reference Exposure Levels ( Monomer and Polymeric Forms ) Technical Support Document for the Derivation of Noncancer Reference Exposure Levels Appendix D 1 SRP Review Draft Prepared by the Office of Environmental Health Hazard Assessment

  2015cites this paper
• Evaluation for a Mutagenicity of 4,4′-Methylenedianiline on Hematopoietic Cells by a Pig-a Gene Mutation Assay in Rats

  2014cites this paper
• Aromatic Amino and Nitro–Amino Compounds and Their Halogenated Derivatives

  2012cites this paper
• Determination of a new biomarker in subjects exposed to 4,4′-methylenediphenyl diisocyanate

  2010cites this paper
• New isocyanate-specific albumin adducts of 4,4'-methylenediphenyl diisocyanate (MDI) in rats.

  2009cites this paper
• Metylenodifenylodiizocyjan - mieszanina izomerów

  2009cites this paper
• Determination of isocyanate biomarkers in construction site workers

  2007cites this paper
• DNA strand breaks in the lymphocytes of workers exposed to diisocyanates: indications of individual differences in susceptibility after low-dose and short-term exposure

  2005cites this paper
• Percutaneous penetration and genotoxicity of 4,4'-methylenedianiline through rat and human skin in vitro.

  2004cites this paper
• Changes in low molecular weight DNA fragmentation in white blood cells after diisocyanate exposure of workers

  2003cites this paper
• DNA damage induced by 4,4'-methylenedianiline in primary cultures of hepatocytes and thyreocytes from rats and humans.

  2002cites this paper
• Review of the occupational exposure to isocyanates: Mechanisms of action

  2002cites this paper
• LACK OF DNA BINDING IN THE RAT NASAL MUCOSA AND OTHER TISSUES OF THE NASAL TOXICANTS ROFLUMILAST, A PHOSPHODIESTERASE 4 INHIBITOR, AND A METABOLITE, 4-AMINO-3,5-DICHLOROPYRIDINE, IN CONTRAST TO THE NASAL CARCINOGEN 2,6-DIMETHYLANILINE*

  2002cites this paper
• Carcinogenic Risk of Toluene Diisocyanate and 4,4′-Methylenediphenyl Diisocyanate: Epidemiological and Experimental Evidence

  2001cites this paper
• Differentiation of the mechanism of micronuclei induced by cysteine and glutathione conjugates of methylenedi-p-phenyl diisocyanate from that of 4,4'-methylenedianiline.

  2001cites this paper
• MDI and TDI: Safety, Health and the Environment: A Source Book and Practical Guide

  2001cites this paper
• Scientific Basis for Swedish Occupational Standards XXII

  2001cites this paper
• Chronic pulmonary effects of respirable methylene diphenyl diisocyanate (MDI) aerosol in rats: combination of findings from two bioassays

  2001cites this paper
• Induction of micronuclei following exposure to methylene di-phenyl diisocyanate: potential genotoxic metabolites.

  2000cites this paper
• Isocyanate-specific hemoglobin adduct in rats exposed to 4, 4'-methylenediphenyl diisocyanate.

  2000cites this paper
• 4,4'-Methylenediphenyl diisocyanate and polymeric 4,4'-methylenediphenyl diisocyanate.

  1999cites this paper
• Toxicological profile for methylenedianiline

  1998cites this paper
• Pathomechanisms and pathophysiology of isocyanate-induced diseases--summary of present knowledge.

  1998cites this paper
• Investigation of the induction of DNA double-strand breaks by methylenediphenyl-4-4'-diisocyanate in cultured human lung epithelial cells.

  1998cites this paper
• Characterization of hemoglobin adducts from a 4, 4'-methylenedianiline metabolite evidently produced by peroxidative oxidation in vivo.

  1998cites this paper
• Distribution and DNA adduct formation of radiolabeled methylenediphenyl-4,4'-diisocyanate (MDI) in the rat after topical treatment.

  1997cites this paper
• Determination of bulky DNA adducts in biomonitoring of carcinogenic chemical exposures: features and comparison of current techniques.

  1997cites this paper
• Determination of bulky DNA adducts in biomonitoring of carcinogenic chemical exposures: features and comparison of current techniques

  1997cites this paper