Treatment of relapsing–remitting multiple sclerosis with natural interferon beta: a multicenter, randomized clinical trial

Ó. Fernández,A. Antiquëdad,T. Arbizu,A. Capdevila,P. D. Castro,J. Sà,JA García-Merino,G. Izquierdo,A. Magalhães,X. Montalbán,JJ Zarranz

Published 1995 in Multiple Sclerosis

ABSTRACT

Preliminary results of a multicenter, randomized study on the effect of natural interferon beta (n-INFN-β) in relapsing-remitting MS are reported. Sixty patients received either no treatment or n-IFN-β) (9 MIU three times a week, subcutaneously). After 6 months, the n-IFN-β-treated group showed a 58% median reduction in the number of active lesions detected on monthly magnetic resonance imaging scans as well as a 38% reduction in the exacerbation rate as compared with the control group. Side-effects were mild and self-limiting. The study continues according to the protocol.

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