Characterization of endothelin-binding sites in human skin and their regulation in primary Raynaud's phenomenon and systemic sclerosis.

No abstract is available for this paper.

• Publication year

  1993

• Venue

  Journal of Investigative Dermatology

• Publication date

  1993-07-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1111/1523-1747.EP12360103PMID 8331298
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Biological profiles of highly potent novel endothelin antagonists selective for the ETA receptor.

  1992cited by this paper
• The selective endothelin ETA receptor antagonist BQ123 antagonizes endothelin-1-mediated mitogenesis.

  1992cited by this paper
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  1992cited by this paper
• Venous smooth muscle contains vasoconstrictor ETB-like receptors.

  1992cited by this paper
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  1992cited by this paper
• Structure-activity relationships of monocyclic endothelin analogs

  1991cited by this paper
• Endothelins produced by endothelial cells promote collagen gel contraction by fibroblasts

  1991cited by this paper
• Elevated plasma levels of endothelin-1 in systemic sclerosis.

  1991cited by this paper
• Increased plasma endothelin levels in patients with Raynaud's phenomenon.

  1991cited by this paper
• Sarafotoxin S6c: an agonist which distinguishes between endothelin receptor subtypes.

  1991cited by this paper
• Down-regulation of endothelin receptors in the ventrolateral medulla of spontaneously hypertensive rats.

  1991cited by this paper
• Endothelins activate Na+/H+ exchange in brain capillary endothelial cells via a high affinity endothelin-3 receptor that is not coupled to phospholipase C.

  1991cited by this paper
• Endothelin, an endothelial-dependent vasoconstrictor in scleroderma. Enhanced production and profibrotic action.

  1991cited by this paper
• Endothelin-1 in human skin: immunolocalization, receptor binding, mRNA expression, and effects on cutaneous microvascular endothelial cells.

  1991cited by this paper
• Image analysis quantification of peptide‐immunoreactive nerves in the skin of patients with Raynaud's phenomenon and systemic sclerosis

  1991cited by this paper
• Endothelins inhibit adenylate cyclase in brain capillary endothelial cells.

  1991cited by this paper
• Endothelin and Raynaud's phenomenon.

  1991cited by this paper
• Digital cutaneous vascular responses to histamine and neuropeptides in Raynaud's phenomenon.

  1991cited by this paper
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  1991cited by this paper
• Presence of non‐selective type of endothelin receptor on vascular endothelium and its linkage to vasodilation

  1991cited by this paper
• Cloning and functional expression of a vascular smooth muscle endothelin 1 receptor.

  1991cited by this paper
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  1990cited by this paper
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  1990cited by this paper
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  1990cited by this paper
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  1990cited by this paper
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  1990cited by this paper
• Pro‐inflammatory mediators induce sustained release of prostaglandin E2 from human dermal microvascular endothelial cells

  1990cited by this paper
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  1990cited by this paper
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  1989cited by this paper
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  1981cited by this paper
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  1981cited by this paper
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  1980cited by this paper
• RAYNAUD'S DISEASE: A CRITICAL REVIEW OF MINIMAL REQUISITES FOR DIAGNOSIS.*

  1932cited by this paper

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• The role of the epidermis in pathogenesis of systemic sclerosis

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  2007cites this paper
• Raynaud-Phänomen in der Dermatologie

  2006cites this paper
• [Raynaud phenomenon in dermatology. Part 1: Pathophysiology and diagnostic approach].

  2006cites this paper
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  2006cites this paper
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• [Physiopathology of Raynaud phenomenon: current data].

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• [Kidney involvement in progressive scleroderma].

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• Raynaud-Phänomen und Sklerodermie

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• [Raynaud phenomenon and scleroderma].

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• Raynaud's phenomenon.

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• Raynaud's Phenomenon.

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• United States Patent ( 10 ) Patent No . : US 9 , 290 , 489 B 2

  year unknowncites this paper