Contributions of epsinR and gadkin to clathrin-mediated intracellular trafficking

Jennifer Hirst,J. Edgar,Georg H. H. Borner,Sam Li,D. Sahlender,R. Antrobus,M. Robinson

Published 2015 in Molecular Biology of the Cell

ABSTRACT

EpsinR and gadkin are two components of intracellular clathrin-coated vesicles whose precise functions are unclear. Rapid depletion of each protein from the available pool using the knocksideways method strongly inhibited the production of intracellular clathrin-coated vesicles, providing new insights into the functions of both proteins.

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