Do adjuvants add to the efficacy and tolerance of bowel preparations? A meta-analysis of randomized trials

No abstract is available for this paper.

• Publication year

  2017

• Venue

  Endoscopy

• Publication date

  2017-10-24

• Fields of study

  Medicine

• Identifiers
  DOI 10.1055/s-0043-119638PMID 29065439
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Simethicone residue remains inside gastrointestinal endoscopes despite reprocessing.

  2016cited by this paper
• Bowel cleansing before colonoscopy: Balancing efficacy, safety, cost and patient tolerance.

  2016cited by this paper
• Split-Dose Preparations Are Superior to Day-Before Bowel Cleansing Regimens: A Meta-analysis.

  2015influential reference
• Does Polyethylene Glycol (PEG) Plus Ascorbic Acid Induce More Mucosal Injuries than Split-Dose 4-L PEG during Bowel Preparation?

  2015cited by this paper
• Lubiprostone Plus PEG Electrolytes Versus Placebo Plus PEG Electrolytes for Outpatient Colonoscopy Preparation: A Randomized, Double-Blind Placebo-Controlled Trial

  2015cited by this paper
• Electrolyte changes after bowel preparation for colonoscopy: A randomized controlled multicenter trial.

  2015influential reference
• A randomized controlled trial comparing polyethylene glycol + ascorbic acid with sodium picosulphate + magnesium citrate solution for bowel cleansing prior to colonoscopy

  2015influential reference
• Randomized controlled trial of low-volume bowel preparation agents for colonic bowel preparation: 2-L polyethylene glycol with ascorbic acid versus sodium picosulfate with magnesium citrate

  2015influential reference
• Split-dose menthol-enhanced PEG vs PEG-ascorbic acid for colonoscopy preparation.

  2015cited by this paper
• A randomized, prospective trial on efficacy and tolerability of low-volume bowel preparation methods for colonoscopy.

  2015influential reference
• Randomized controlled trial comparing Moviprep® and Phosphoral® as bowel cleansing agents in patients undergoing colonoscopy

  2014cited by this paper
• Randomized, controlled trial of 2 L polyethylene glycol plus ascorbate components versus sodium phosphate for bowel cleansing prior to colonoscopy for cancer screening

  2014influential reference
• Optimizing Adequacy of Bowel Cleansing for Colonoscopy: Recommendations From the US Multi-Society Task Force on Colorectal Cancer

  2014cited by this paper
• Randomized trial of 2‐L polyethylene glycol + ascorbic acid versus 4‐L polyethylene glycol as bowel cleansing for colonoscopy in an optimal setting

  2014cited by this paper
• Efficacy of morning-only 4 liter sulfa free polyethylene glycol vs 2 liter polyethylene glycol with ascorbic acid for afternoon colonoscopy.

  2014influential reference
• Sodium Picosulfate with Magnesium Citrate (SPMC) Plus Laxative Is a Good Alternative to Conventional Large Volume Polyethylene Glycol in Bowel Preparation: A Multicenter Randomized Single-Blinded Trial

  2014influential reference
• A Meta-Analysis of Randomized Controlled Trials of Low-Volume Polyethylene Glycol plus Ascorbic Acid versus Standard-Volume Polyethylene Glycol Solution as Bowel Preparations for Colonoscopy

  2014cited by this paper
• A low-volume polyethylene glycol plus ascorbate solution for bowel cleansing prior to colonoscopy: the NORMO randomised clinical trial.

  2013cited by this paper
• Bowel preparation for colonoscopy: European Society of Gastrointestinal Endoscopy (ESGE) Guideline

  2013influential reference
• Validation of the Harefield Cleansing Scale: a tool for the evaluation of bowel cleansing quality in both research and clinical practice.

  2013cited by this paper
• Ascorbic acid and low-volume polyethylene glycol for bowel preparation prior to colonoscopy: A meta-analysis

  2013cited by this paper
• A new low-volume isosmotic polyethylene glycol solution plus bisacodyl versus split-dose 4 L polyethylene glycol for bowel cleansing prior to colonoscopy: a randomised controlled trial.

  2013influential reference
• A Dual-Action, Low-Volume Bowel Cleanser Administered the Day Before Colonoscopy: Results From the SEE CLEAR II Study

  2013influential reference
• Safety, Patient’s Tolerance, and Efficacy of a 2-Liter Vitamin C-Enriched Macrogol Bowel Preparation: A Randomized, Endoscopist-Blinded Prospective Comparison With a 4-Liter Macrogol Solution

  2013cited by this paper
• Same-day 2-L PEG-citrate-simethicone plus bisacodyl vs split 4-L PEG: Bowel cleansing for late-morning colonoscopy.

  2013influential reference
• Split-dose administration of a dual-action, low-volume bowel cleanser for colonoscopy: the SEE CLEAR I study.

  2013influential reference
• Low-volume polyethylene glycol and bisacodyl for bowel preparation prior to colonoscopy: a meta-analysis

  2013cited by this paper
• Can mosapride citrate reduce the volume of lavage solution for colonoscopy preparation?

  2013cited by this paper
• Randomized Trial of Gatorade/Polyethylene Glycol With or Without Bisacodyl and NuLYTELY for Colonoscopy Preparation

  2012influential reference
• Efficacy of Prokinetics with a Split-Dose of Polyethylene Glycol in Bowel Preparation for Morning Colonoscopy: A Randomized Controlled Trial

  2012influential reference
• Split-Dosed MiraLAX/Gatorade Is an Effective, Safe, and Tolerable Option for Bowel Preparation in Low-Risk Patients: A Randomized Controlled Study

  2012influential reference
• A randomized controlled trial evaluating a new 2-L PEG solution plus ascorbic acid vs 4-L PEG for bowel cleansing prior to colonoscopy.

  2012influential reference
• Meta‐analysis: the relative efficacy of oral bowel preparations for colonoscopy 1985–2010

  2012cited by this paper
• Colonoscopy Preparation: Polyethylene Glycol with Gatorade Is as Safe and Efficacious as Four Liters of Polyethylene Glycol with Balanced Electrolytes

  2012cited by this paper
• Consensus guidelines for the safe prescription and administration of oral bowel-cleansing agents

  2012cited by this paper
• Low-volume bowel preparation is inferior to standard 4 l polyethylene glycol

  2011influential reference
• Preparation before colonoscopy: a randomized controlled trial comparing different regimes

  2011cited by this paper
• Systematic review and meta-analysis of randomized controlled trials of Simethicone for gastrointestinal endoscopic visibility

  2011cited by this paper
• A randomized controlled trial of four precolonoscopy bowel cleansing regimens.

  2011cited by this paper
• Randomised clinical trial: MiraLAX vs. Golytely – a controlled study of efficacy and patient tolerability in bowel preparation for colonoscopy

  2011cited by this paper
• Acceptability and side-effects of colonoscopy and sigmoidoscopy in a screening setting

  2011cited by this paper
• A randomized, controlled, double-blind trial of the adjunct use of Clebopride in polyethylene glycol electrolyte (PEG) solution for colonoscopy preparation.

  2010influential reference
• Low-volume PEG plus ascorbic acid versus high-volume PEG as bowel preparation for colonoscopy

  2010influential reference
• Effective bowel cleansing before colonoscopy: a randomized study of split-dosage versus non-split dosage regimens of high-volume versus low-volume polyethylene glycol solutions.

  2010influential reference
• Lubiprostone used with polyethylene glycol in diabetic patients enhances colonoscopy preparation quality.

  2010influential reference
• Efficacy and Tolerability of Split-Dose Magnesium Citrate: Low-Volume (2 Liters) Polyethylene Glycol vs. Single- or Split-Dose Polyethylene Glycol Bowel Preparation for Morning Colonoscopy

  2010cited by this paper
• A Feasibility Study of Probiotics Pretreatment as a Bowel Preparation for Colonoscopy in Constipated Patients

  2010influential reference
• Administration of olive oil followed by a low volume of polyethylene glycol-electrolyte lavage solution improves patient satisfaction with right-side colonic cleansing over administration of the conventional volume of polyethylene glycol-electrolyte lavage solution for colonoscopy preparation.

  2009cited by this paper
• Improving quality of colonoscopy by adding simethicone to sodium phosphate bowel preparation.

  2009cited by this paper
• Randomized Study Comparing Two Regimens of Oral Sodium Phosphates Solution Versus Low-Dose Polyethylene Glycol and Bisacodyl

  2009influential reference
• A Randomized Clinical Study Evaluating the Safety and Efficacy of a New, Reduced-Volume, Oral Sulfate Colon-Cleansing Preparation for Colonoscopy

  2009influential reference
• Comprehensive validation of the Boston Bowel Preparation Scale.

  2009influential reference
• Pico-Salax Plus Two-Day Bisacodyl Is Superior to Pico-Salax Alone or Oral Sodium Phosphate for Colon Cleansing Before Colonoscopy

  2009influential reference
• Bowel Preparation for Colonoscopy with Sodium Phosphate Solution versus Polyethylene Glycol-Based Lavage: A Multicenter Trial

  2008influential reference
• Single-Dose Lubiprostone Along With Split-Dose PEG Solution Without Dietary Restrictions for Bowel Cleansing Prior to Colonoscopy: A Randomized, Double-Blind, Placebo-Controlled Trial

  2008cited by this paper
• Randomized Trial of Low-Volume PEG Solution Versus Standard PEG + Electrolytes for Bowel Cleansing Before Colonoscopy

  2008cited by this paper
• A randomised controlled trial of a new 2 litre polyethylene glycol solution versus sodium picosulphate + magnesium citrate solution for bowel cleansing prior to colonoscopy.

  2008influential reference
• Alverine citrate plus simethicone reduces cecal intubation time in colonoscopy - a randomized study.

  2008cited by this paper
• A Randomized, Multicenter Study Comparing the Safety and Efficacy of Sodium Phosphate Tablets With 2L Polyethylene Glycol Solution Plus Bisacodyl Tablets for Colon Cleansing

  2007influential reference
• The Boston bowel preparation scale: a valid and reliable instrument for colonoscopy-oriented research.

  2007influential reference
• Comparison of Reduced Volume versus Four-Liter Electrolyte Lavage Solutions for Colon Cleansing

  2006cited by this paper
• Results of a prospective randomised multicentre controlled trial comparing a new 2‐L ascorbic acid plus polyethylene glycol and electrolyte solution vs. sodium phosphate solution in patients undergoing elective colonoscopy

  2006influential reference
• Combined low volume polyethylene glycol solution plus stimulant laxatives versus standard volume polyethylene glycol solution: a prospective, randomized study of colon cleansing before colonoscopy.

  2006influential reference
• A consensus document on bowel preparation before colonoscopy: prepared by a task force from the American Society of Colon and Rectal Surgeons (ASCRS), the American Society for Gastrointestinal Endoscopy (ASGE), and the Society of American Gastrointestinal and Endoscopic Surgeons (SAGES)

  2006cited by this paper
• Use of tegaserod along with polyethylene glycol electrolyte solution for colonoscopy bowel preparation: a prospective, randomized, double‐blind, placebo‐controlled study

  2006cited by this paper
• Polyethylene Glycol versus Sodium Phosphate in Bowel Cleansing for Colonoscopy: a Randomized Trial

  2005influential reference
• The administration of cisapride as an adjuvant to PEG-electrolyte solution for colonic cleansing: a double-blind randomized study.

  2005cited by this paper
• A Prospective Randomized Trial Comparing Low-Dose Oral Sodium Phosphate Plus Stimulant Laxatives with Large Volume Polyethylene Glycol Solution for Colon Cleansing

  2004influential reference
• Validation of a new scale for the assessment of bowel preparation quality.

  2004cited by this paper
• A randomized single-blind trial of whole versus split-dose polyethylene glycol-electrolyte solution for colonoscopy preparation.

  2003influential reference
• Bowel cleansing for diagnostic colonoscopy: which method is preferable? Istanbul experience

  2003influential reference
• Comparison of reduced volume versus four liters sulfate-free electrolyte lavage solutions for colonoscopy colon cleansing

  2003cited by this paper
• The safety profile of oral sodium phosphate for colonic cleansing before colonoscopy in adults.

  2002cited by this paper
• Cisapride does not improve precolonoscopy bowel preparation with either sodium phosphate or polyethylene glycol electrolyte lavage.

  2001influential reference
• Oral sodium phosphate solution is a superior colonoscopy preparation to polyethylene glycol with bisacodyl

  2000influential reference
• Prospective, randomized, controlled comparison of the use of polyethylene glycol electrolyte lavage solution in four-liter versus two-liter volumes and pretreatment with either magnesium citrate or bisacodyl for colonoscopy preparation.

  1998cited by this paper
• The quest for a more acceptable bowel preparation: comparison of a polyethylene glycol/electrolyte solution and a mannitol/Picolax mixture for colonoscopy.

  1995influential reference
• Identifying relevant studies for systematic reviews

  1995cited by this paper
• Prospective, randomized trial comparing a new sodium phosphate-bisacodyl regimen with conventional PEG-ES lavage for outpatient colonoscopy preparation.

  1995influential reference
• The effectiveness of simethicone in improving visibility during colonoscopy when given with a sodium phosphate solution: a double-bind randomized study.

  1995cited by this paper
• The effects of cisapride on the quality and tolerance of colonic lavage: a double-blind randomized study.

  1995cited by this paper
• Bisacodyl reduces the volume of polyethylene glycol solution required for bowel preparation

  1994influential reference
• Prospective, randomized trial comparing sodium phosphate solution with polyethylene glycol-electrolyte lavage for colonoscopy preparation.

  1993cited by this paper
• The use of GoLYTELY and Dulcolax in combination in outpatient colonoscopy.

  1993cited by this paper
• Efficacy and tolerability of polyethylene glycol‐electrolyte lavage solution with and without simethicone in the preparation of patients with inflammatory bowel disease for colonoscopy

  1993cited by this paper
• Addition of enemas to oral lavage preparation for colonoscopy is not necessary.

  1992cited by this paper
• A randomised blinded study in colonic lavage for colonoscopy.

  1991cited by this paper
• Practical statistics for medical research

  1990cited by this paper
• Comparison of Three Colon Cleansing Methods: Evaluation of A Randomized Clinical Trial with 300 Ambulatory Patients

  1989influential reference
• The effect of simethicone on colonic visibility after night-prior colonic lavage. A double-blind randomized study.

  1989cited by this paper
• Improvement of oral colonic lavage with supplemental simethicone

  1988cited by this paper
• The effectiveness of simethicone in improving visibility during colonoscopy: a double-blind randomized study.

  1988cited by this paper
• Effect of bisacodyl on gut lavage cleansing for colonoscopy.

  1987cited by this paper
• Golytely lavage--is metoclopramide necessary?

  1985cited by this paper

• Optimizing Bowel Preparation Quality for Colonoscopy: Consensus Recommendations by the US Multi-Society Task Force on Colorectal Cancer.

  2025cites this paper
• A Retrospective Study of the Real-World Effectiveness of 8-L Polyethylene Glycol-Electrolyte Lavage Solution (PEG-ELS) Prep After Failure of Standard Prep.

  2025cites this paper
• Efficacy and safety of polyethylene glycol in combination with linaclotide versus polyethylene glycol alone for colonoscopy: a grade-assessed systematic review and meta-analysis

  2025cites this paper
• Optimizing bowel preparation quality for colonoscopy: consensus recommendations by the US Multi-Society Task Force on Colorectal Cancer.

  2025cites this paper
• Optimizing Bowel Preparation Quality for Colonoscopy: Consensus Recommendations by the US Multi-Society Task Force on Colorectal Cancer.

  2025cites this paper
• Colon Bowel Preparation in the Era of Artificial Intelligence: Is There Potential for Enhancing Colon Bowel Cleansing?

  2023cites this paper
• 3 L split-dose polyethylene glycol is superior to 2 L polyethylene glycol in colonoscopic bowel preparation in relatively high-BMI (≥ 24 kg/m2) individuals: a multicenter randomized controlled trial

  2023cites this paper
• The Efficacy of Senna Bowel Preparation for Colonoscopy

  2022influential citation
• Comparison of 1L Adjuvant Auxiliary Preparations with 2L Solely Polyethylene Glycol plus Ascorbic Acid Regime for Bowel Cleaning: A Meta-analysis of Randomized, Controlled Trials

  2021cites this paper
• Can adjuncts to bowel preparation for colonoscopy improve patient experience and result in superior bowel cleanliness? A systematic review and meta-analysis

  2020cites this paper
• Strategies to Improve Inadequate Bowel Preparation for Colonoscopy

  2019influential citation
• Strategies to optimise the quality of bowel cleansing

  2019cites this paper
• Strategies to optimise the quality of bowel cleansing.

  2019cites this paper
• Gum chewing for bowel preparation

  2018cites this paper
• Systematic review and meta-analysis of colon cleansing preparations in patients with inflammatory bowel disease

  2017cites this paper