Neomycin Is an Agonist at a Polyamine Site on the N‐Methyl‐D‐Aspartate Receptor

No abstract is available for this paper.

• Publication year

  1992

• Venue

  Journal of Neurochemistry

• Publication date

  1992-12-01

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1111/j.1471-4159.1992.tb10099.xPMID 1359015
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The inhibition of [125I]ω-conotoxin GVIA binding to neuronal membranes by neomycin may be mediated by a GTP-binding protein

  1991cited by this paper
• Ifenprodil blocks N-methyl-D-aspartate receptors by a two-component mechanism.

  1991cited by this paper
• Spermine reciprocally changes the affinity of NMDA receptor agonists and antagonists.

  1991cited by this paper
• Modulation of the NMDA receptor by polyamines.

  1991cited by this paper
• Competitive inhibition of magnesium-induced [3H]N-(1-[thienyl] cyclohexyl)piperidine binding by arcaine: evidence for a shared spermidine-magnesium binding site.

  1990cited by this paper
• Arcaine uncovers dual interactions of polyamines with the N-methyl-D-aspartate receptor.

  1990cited by this paper
• A family of glutamate receptor genes: evidence for the formation of heteromultimeric receptors with distinct channel properties.

  1990cited by this paper
• Characterization of the stimulatory and inhibitory effects of polyamines on [3H]N-(1-[thienyl]cyclohexyl) piperidine binding to the N-methyl-D-aspartate receptor ionophore complex.

  1990cited by this paper
• Stereoselectivity for the (R)‐Enantiomer of HA‐966 (l‐Hydroxy‐3‐Aminopyrrolidone‐2) at the Glycine Site of the N‐Methyl‐d‐Aspartate Receptor Complex

  1990cited by this paper
• Arcaine is a competitive antagonist of the polyamine site on the NMDA receptor.

  1990cited by this paper
• Stereoselective enhancement by (R)-HA-966 of the binding of [3H]CPP to the NMDA receptor complex.

  1990cited by this paper
• Effects of polyamines on the binding of [3H]MK-801 to the N-methyl-D-aspartate receptor: pharmacological evidence for the existence of a polyamine recognition site.

  1989cited by this paper
• Ifenprodil is a novel type of N-methyl-D-aspartate receptor antagonist: interaction with polyamines.

  1989cited by this paper
• Ifenprodil and SL 82.0715 are antagonists at the polyamine site of the N-methyl-D-aspartate (NMDA) receptor.

  1989influential reference
• Cooperative Modulation of [3H]MK‐801 Binding to the N‐Methyl‐d‐Aspartate Receptor‐Ion Channel Complex by l‐Glutamate, Glycine, and Polyamines

  1988cited by this paper
• Multiple sites for the regulation of the N-methyl-D-aspartate receptor.

  1988cited by this paper

• Pasireotide prevents nuclear factor of activated T cells nuclear translocation and acts as a protective agent in aminoglycoside‐induced auditory hair cell loss

  2016cites this paper
• On the Interaction of Neomycin with the Slow Vacuolar Channel of Arabidopsis thaliana

  2006cites this paper
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  2005cites this paper
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  2004cites this paper
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  2004cites this paper
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• [Aminoglycoside- and cisplatin-ototoxicity: from basic science to clinics].

  2004cites this paper
• Evidence for the involvement of GABA(A) receptor blockade in convulsions induced by cephalosporins.

  2003cites this paper
• A new aspect of aminoglycoside ototoxicity: impairment of cochlear dopamine release

  2001cites this paper
• Cell and Molecular Biology of the Ear

  2000cites this paper
• Are vestibular hair cells excited to death by aminoglycoside antibiotics?

  2000cites this paper
• The antibacterial and NMDA receptor activating properties of aminoglycosides are dissociable.

  2000cites this paper
• Complementary roles of neurotrophin 3 and a N-methyl-D-aspartate antagonist in the protection of noise and aminoglycoside-induced ototoxicity.

  2000cites this paper
• Mechanism and Prevention of Aminoglycoside-Induced Hearing Loss

  2000cites this paper
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  1999cites this paper
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  1999cites this paper
• Aminoglycoside neurotoxicity involves NMDA receptor activation.

  1999cites this paper
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  1999cites this paper
• Increase in glutamate-aspartate transporter (GLAST) mRNA during kanamycin-induced cochlear insult in rats.

  1999cites this paper
• Dizocilpine attenuates streptomycin-induced vestibulotoxicity in rats.

  1999cites this paper
• Attenuation of aminoglycoside-induced cochlear damage with the metabolic antioxidant alpha-lipoic acid.

  1999cites this paper
• Polyamine-like actions of aminoglycosides at recombinant N-methyl-D-aspartate receptors.

  1999cites this paper
• Polyamine-like actions of aminoglycosides and aminoglycoside derivatives at NMDA receptors.

  1998cites this paper
• Sodium and Ionic Strength Sensing by the Calcium Receptor*

  1998cites this paper
• Neomycin inhibition of intestinal putrescine uptake.

  1998cites this paper
• Loss of spiral ganglion cells as primary manifestation of aminoglycoside ototoxicity.

  1998cites this paper
• Multiple sites of action of neomycin, Mg2+ and spermine on the NMDA receptors of rat hippocampal CA1 pyramidal neurones

  1998cites this paper
• Prevention of aminoglycoside-induced hearing loss.

  1997cites this paper
• The Ca2+-sensing receptor: a target for polyamines.

  1997cites this paper
• Deficient cation channel regulation in neurons from mice with targeted disruption of the extracellular Ca2+-sensing receptor gene.

  1997cites this paper
• The Ca 2 -sensing receptor: a target for polyamines

  1997influential citation
• Aminoglycoside excitement silences hearing

  1996cites this paper
• Aminoglycosides and polyamines: targets and effects in the mammalian organism of two important groups of natural aliphatic polycations.

  1996cites this paper
• Polyamine deprivation provokes an antalgic effect.

  1996cites this paper
• Progress in Drug Research/Fortschritte der Arzneimittelforschung/Progrès des recherches pharmaceutiques

  1996cites this paper
• N–Methyl–D–aspartate antagonists limit aminoglycoside antibiotic–induced hearing loss

  1996cites this paper
• Acute mechanical hyperalgesia in the rat can be produced by coactivation of spinal ionotropic AMPA and metabotropic glutamate receptors, activation of phospholipase A2 and generation of cyclooxygenase products.

  1996cites this paper
• Polyamine regulation of N-methyl-D-aspartate receptor channels.

  1995cites this paper
• Characterization of the effects of polyamines on the modulation of the N-methyl-D-aspartate receptor by glycine.

  1995cites this paper
• A photoaffinity probe for the polyamine site regulating the NMDA receptor.

  1995cites this paper
• Effects of Systematically Administered Polyamines on Imipramine Immobility Action in Rats

  1995cites this paper
• Modulation of N-methyl-D-aspartate (NMDA) antagonist-induced darting behaviour by the peptidomimetic PAMTA.

  1995cites this paper
• Mechanisms influencing stimulatory effects of spermine at recombinant N-methyl-D-aspartate receptors.

  1994cites this paper
• Further characterization of [3H]ifenprodil binding in rat brain.

  1994cites this paper
• [3H]Dizocilpine Association Kinetics Distinguish Stimulatory and Inhibitory Polyamine Sites of N‐Methyl‐d‐Aspartate Receptors

  1994cites this paper
• Autoradiographic Distribution and Characteristics of High‐ and Low‐Affinity Polyamine‐Sensitive [3H]Ifenprodil Sites in the Rat Brain: Possible Relationship to NMDAR2B Receptors and Calmodulin

  1994cites this paper
• Polyamine-like actions of peptides derived from conantokin-G, an N-methyl-D-aspartate (NMDA) antagonist.

  1993cites this paper