Binding modes of the initiator and inhibitor forms of the replication protein pi to the gamma ori iteron of plasmid R6K.

No abstract is available for this paper.

• Publication year

  2004

• Venue

  Journal of Biological Chemistry

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  PMID 15247259
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Isomerization and apparent DNA bending by pi, the replication protein of plasmid R6K.

  2004cited by this paper
• Plasmid P1 RepA Is Homologous to the F Plasmid RepE Class of Initiators*

  2004cited by this paper
• Biochemical Investigations of Control of Replication Initiation of Plasmid R6K*

  2004cited by this paper
• A conformational switch between transcriptional repression and replication initiation in the RepA dimerization domain

  2003cited by this paper
• Remodeling of replication initiator proteins

  2003cited by this paper
• High resolution contact probing of the Lrp‐like DNA‐binding protein Ss‐Lrp from the hyperthermoacidophilic crenarchaeote Sulfolobus solfataricus P2

  2002cited by this paper
• Long CTG·CAG Repeats from Myotonic Dystrophy Are Preferred Sites for Intermolecular Recombination*

  2002cited by this paper
• Strong minor groove base conservation in sequence logos implies DNA distortion or base flipping during replication and transcription initiation.

  2001cited by this paper
• Monomer/dimer ratios of replication protein modulate the DNA strand-opening in a replication origin.

  2001cited by this paper
• Dimers of π Protein Bind the A+T-Rich Region of the R6K γ Origin near the Leading-Strand Synthesis Start Sites: Regulatory Implications

  2000cited by this paper
• Hexahistidine (His6)-tag dependent protein dimerization: a cautionary tale.

  1999cited by this paper
• Crystal structure of a prokaryotic replication initiator protein bound to DNA at 2.6 Å resolution

  1999cited by this paper
• Regulatory implications of protein assemblies at the gamma origin of plasmid R6K - a review.

  1998cited by this paper
• Assemblies of replication initiator protein on symmetric and asymmetric DNA sequences depend on multiple protein oligomerization surfaces.

  1998cited by this paper
• DNA strand breaking by the hydroxyl radical is governed by the accessible surface areas of the hydrogen atoms of the DNA backbone.

  1998cited by this paper
• Two forms of replication initiator protein: positive and negative controls.

  1997cited by this paper
• Replication control of plasmid P1 and its host chromosome: the common ground.

  1997cited by this paper
• Preponderance of Fis-binding sites in the R6K gamma origin and the curious effect of the penicillin resistance marker on replication of this origin in the absence of Fis

  1996cited by this paper
• Initiator protein pi can bind independently to two domains of the gamma origin core of plasmid R6K: the direct repeats and the A+T-rich segment.

  1996cited by this paper
• The interaction of RepC initiator with iterons in the replication of the broad host-range plasmid RSF1010.

  1995cited by this paper
• Cooperative binding of initiator protein to replication origin conferred by single amino acid substitution.

  1994cited by this paper
• Information analysis of sequences that bind the replication initiator RepA.

  1993cited by this paper
• DnaJ, DnaK, and GrpE heat shock proteins are required in oriP1 DNA replication solely at the RepA monomerization step.

  1992cited by this paper
• Activation of distant replication origins in vivo by DNA looping as revealed by a novel mutant form of an initiator protein defective in cooperativity at a distance.

  1992cited by this paper
• Function of DnaJ and DnaK as chaperones in origin-specific DNA binding by RepA

  1991cited by this paper
• Negative control of plasmid R6K replication: possible role of intermolecular coupling of replication origins.

  1989cited by this paper
• Hydroxyl radical footprinting: a high-resolution method for mapping protein-DNA contacts.

  1987cited by this paper
• Effect of non-contacted bases on the affinity of 434 operator for 434 repressor and Cro

  1987cited by this paper
• Missing contact probing of DNA-protein interactions.

  1987cited by this paper
• Binding of purified wild-type and mutant pi initiation proteins to a replication origin region of plasmid R6K.

  1986cited by this paper
• Conformational changes in a replication origin induced by an initiator protein.

  1985cited by this paper
• Mutations in direct repeat sequences and in a conserved sequence adjacent to the repeats result in a defective replication origin in plasmid R6K.

  1985cited by this paper
• Autorepressor properties of the pi-initiation protein encoded by plasmid R6K

  1985cited by this paper
• The replication initiator protein of plasmid R6K tagged with beta-galactosidase shows sequence-specific DNA-binding.

  1983cited by this paper
• Plasmid R6K DNA replication. II. Direct nucleotide sequence repeats are required for an active gamma-origin.

  1982cited by this paper
• Sequencing end-labeled DNA with base-specific chemical cleavages.

  1980cited by this paper
• Requirement of a plasmid-encoded protein for replication in vitro of plasmid R6K.

  1978cited by this paper
• Plasmid incompatibility.

  1978cited by this paper

• Molecular analysis of the replication functions of the bifidobacterial conjugative megaplasmid pMP7017

  2021cites this paper
• Molecular Dissection of the Essential Features of the Origin of Replication of the Second Vibrio cholerae Chromosome

  2015cites this paper
• Characterization of a replication locus and formation of a higher-order complex between RepA protein and two inverted repeats in Streptomyces plasmid pSV1.

  2013cites this paper
• Plasmid R6K replication control.

  2013cites this paper
• AT-rich region and repeated sequences - the essential elements of replication origins of bacterial replicons.

  2012influential citation
• Replication regulation of Vibrio cholerae chromosome II involves initiator binding to the origin both as monomer and as dimer

  2012cites this paper
• Investigations of π Initiator Protein-mediated Interaction between Replication Origins α and γ of the Plasmid R6K*

  2009cites this paper
• Nucleotide sequence of pOLA52: a conjugative IncX1 plasmid from Escherichia coli which enables biofilm formation and multidrug efflux.

  2008cites this paper
• Cooperative binding mode of the inhibitors of R6K replication, pi dimers.

  2008cites this paper
• Fluorescence studies of the replication initiator protein RepA in complex with operator and iteron sequences and free in solution

  2008cites this paper
• The ColE2-P9 Rep protein binds to the origin DNA as a monomer.

  2007cites this paper
• Structure-Based Functional Analysis of the Replication Protein of Plasmid R6K: Key Amino Acids at the π/DNA Interface

  2007cites this paper
• Conjugal Transfer of Plasmid R6K γ ori Minireplicon Derivatives from Escherichia coli to Various Genera of Pathogenic Bacteria

  2007cites this paper
• Mechanism of origin activation by monomers of R6K-encoded pi protein.

  2007cites this paper
• Structure-based functional analysis of plasmid R 6 K ’ s replication protein : 1 Key amino acids at the π / DNA interface 2 3

  2007cites this paper
• Small deletion variants of the replication protein, pi, and their potential for over-replication-based antimicrobial activity.

  2006cites this paper
• Early events in the binding of the pPS10 replication protein RepA to single iteron and operator DNA sequences.

  2006cites this paper
• Role of pi dimers in coupling ("handcuffing") of plasmid R6K's gamma ori iterons.

  2005cites this paper