mAngiogenin-3, a target gene of oncoprotein E2a-Pbx1, encodes a new angiogenic member of the angiogenin family.

No abstract is available for this paper.

• Publication year

  1999

• Venue

  Growth Factors

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.3109/08977199909103521PMID 10595312
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Effect of Basic Fibroblast Growth Factor, Vascular Endothelial Growth Factor/Vascular Permeability Factor, and Host Microenvironment

  2007cited by this paper
• Structural features that determine the enzymatic potency and specificity of human angiogenin: threonine-80 and residues 58-70 and 116-123.

  1998cited by this paper
• Meis1 and pKnox1 bind DNA cooperatively with Pbx1 utilizing an interaction surface disrupted in oncoprotein E2a-Pbx1.

  1997cited by this paper
• Neovasculature induced by vascular endothelial growth factor is fenestrated.

  1997cited by this paper
• Heterodimerization of Hox proteins with Pbx1 and oncoprotein E2a-Pbx1 generates unique DNA-binding specificities at nucleotides predicted to contact the N-terminal arm of the Hox homeodomain – demonstration of Hox-dependent targeting of E2a-Pbx1 in vivo

  1997cited by this paper
• E2a-Pbx1 induces aberrant expression of tissue-specific and developmentally regulated genes when expressed in NIH 3T3 fibroblasts

  1997cited by this paper
• A putative angiogenin receptor in angiogenin-responsive human endothelial cells.

  1997cited by this paper
• An angiogenic protein from bovine serum and milk--purification and primary structure of angiogenin-2.

  1997cited by this paper
• Characterization of mouse angiogenin-related protein: implications for functional studies on angiogenin.

  1996cited by this paper
• Crystal structure of bovine angiogenin at 1.5-A resolution.

  1995cited by this paper
• Angiogenin antagonists prevent tumor growth in vivo.

  1995cited by this paper
• Modulation by bovine angiogenin of tubular morphogenesis and expression of plasminogen activator in bovine endothelial cells.

  1995cited by this paper
• Hox gene products modulate the DNA binding activity of Pbx1 and Pbx2.

  1995cited by this paper
• The mouse angiogenin gene family: structures of an angiogenin-related protein gene and two pseudogenes.

  1995cited by this paper
• Increased microvascular permeability and endothelial fenestration induced by vascular endothelial growth factor.

  1995cited by this paper
• A monoclonal antibody to human angiogenin suppresses tumor growth in athymic mice.

  1994cited by this paper
• Fusion with E2A converts the Pbx1 homeodomain protein into a constitutive transcriptional activator in human leukemias carrying the t(1;19) translocation

  1994cited by this paper
• The widespread expression of angiogenin in different human cells suggests a biological function not only related to angiogenesis.

  1994cited by this paper
• Role of glutamine-117 in the ribonucleolytic activity of human angiogenin.

  1994cited by this paper
• YY1 represses rat serum amyloid A1 gene transcription and is antagonized by NF-kappa B during acute-phase response

  1994cited by this paper
• Crystal structure of human angiogenin reveals the structural basis for its functional divergence from ribonuclease.

  1994cited by this paper
• Angiogenin promotes invasiveness of cultured endothelial cells by stimulation of cell-associated proteolytic activities.

  1994cited by this paper
• Nuclear translocation of angiogenin in proliferating endothelial cells is essential to its angiogenic activity.

  1994cited by this paper
• Oncoprotein E2A-Pbx1 immortalizes a myeloid progenitor in primary marrow cultures without abrogating its factor-dependence.

  1994cited by this paper
• Angiogenin enhances actin acceleration of plasminogen activation.

  1993cited by this paper
• Chimeric homeobox gene E2A-PBX1 induces proliferation, apoptosis, and malignant lymphomas in transgenic mice.

  1993cited by this paper
• Actin is a binding protein for angiogenin.

  1993cited by this paper
• Characterization and sequencing of rabbit, pig and mouse angiogenins: discernment of functionally important residues and regions.

  1993cited by this paper
• Alteration of the enzymatic specificity of human angiogenin by site-directed mutagenesis.

  1993cited by this paper
• Actin is a surface component of calf pulmonary artery endothelial cells in culture.

  1993cited by this paper
• E2A-Pbx1, the t(1;19) translocation protein of human pre-B-cell acute lymphocytic leukemia, causes acute myeloid leukemia in mice

  1993cited by this paper
• Pbx1 is converted into a transcriptional activator upon acquiring the N-terminal region of E2A in pre-B-cell acute lymphoblastoid leukemia.

  1993cited by this paper
• Importance of asparagine-61 and asparagine-109 to the angiogenic activity of human angiogenin.

  1992cited by this paper
• Identification of functional arginines in human angiogenin by site-directed mutagenesis.

  1992cited by this paper
• PBX2 and PBX3, new homeobox genes with extensive homology to the human proto-oncogene PBX1

  1991cited by this paper
• The human t(1;19) translocation in pre-B ALL produces multiple nuclear E2A-Pbx1 fusion proteins with differing transforming potentials.

  1991cited by this paper
• Dual site model for the organogenic activity of angiogenin.

  1991cited by this paper
• Chromosomal translocation t(1;19) results in synthesis of a homeobox fusion mRNA that codes for a potential chimeric transcription factor.

  1990cited by this paper
• Isolation and sequencing of mouse angiogenin DNA.

  1990cited by this paper
• A new homeobox gene contributes the DNA binding domain of the t(1;19) translocation protein in pre-B ALL.

  1990cited by this paper
• Mutagenesis of residues flanking Lys-40 enhances the enzymatic activity and reduces the angiogenic potency of angiogenin.

  1990cited by this paper
• A covalent angiogenin/ribonuclease hybrid with a fourth disulfide bond generated by regional mutagenesis.

  1989cited by this paper
• A covalent angiogenin/ribonuclease hybrid with a fourth disulfide bond generated by regional mutagenesis.

  1989cited by this paper
• Site-directed mutagenesis of histidine-13 and histidine-114 of human angiogenin. Alanine derivatives inhibit angiogenin-induced angiogenesis.

  1989cited by this paper
• Role of lysines in human angiogenin: chemical modification and site-directed mutagenesis.

  1989cited by this paper
• Angiogenin activates endothelial cell phospholipase C.

  1988cited by this paper
• Mutagenesis of aspartic acid-116 enhances the ribonucleolytic activity and angiogenic potency of angiogenin.

  1988cited by this paper
• Expression of Met-(-1) angiogenin in Escherichia coli: conversion to the authentic less than Glu-1 protein.

  1988cited by this paper
• The complete amino acid sequence of bovine milk angiogenin

  1988cited by this paper
• Angiogenin mRNA in human tumor and normal cells.

  1987cited by this paper
• Isolation of angiogenin from normal human plasma.

  1987cited by this paper
• Characteristic ribonucleolytic activity of human angiogenin.

  1986cited by this paper
• Isolation and characterization of angiogenin, an angiogenic protein from human carcinoma cells.

  1985cited by this paper
• Amino acid sequence of human tumor derived angiogenin.

  1985cited by this paper
• The angiogenic activity of the fibroblast and epidermal growth factor.

  1979cited by this paper
• Fenestrations in regenerating skeletal muscle capillaries.

  1977cited by this paper
• Avascular and vascular phases of tumour growth in the chick embryo.

  1977cited by this paper
• Studies on inflammation

  1963cited by this paper

• Ribonucleases of Mice and Men: Unveiling the Roles of the RNase A Superfamily in Host Defence

  2025cites this paper
• Comprehensive summary: the role of PBX1 in development and cancers

  2024cites this paper
• Human and mouse angiogenins: Emerging insights and potential opportunities

  2022cites this paper
• Gut microbiota - architects of small intestinal capillaries.

  2018cites this paper
• Roles of Id3 and IL-13 in a Mouse Model of Autoimmune Exocrinopathy

  2015cites this paper
• Relationship of angiogenin to pathophysiology of diseases

  2015cites this paper
• E proteins in lymphocyte development and lymphoid diseases.

  2014influential citation
• Crystal structures of murine angiogenin-2 and -3 – probing ‘structure – function’ relationships amongst angiogenin homologues

  2012cites this paper
• Antiangiogenesis in myelodysplastic syndrome.

  2011cites this paper
• 24B-Cell Acute Lymphoblastic Leukemia

  2010cites this paper
• Precursor B-Cell Acute Lymphoblastic Leukemia

  2010cites this paper
• Mutational dynamics of murine angiogenin duplicates

  2010cites this paper
• DNA Micro-Array Gene Expression Profiling of Angiogenesis in Collagen Gel Culture

  2008cites this paper
• Biological and structural features of murine angiogenin-4, an angiogenic protein.

  2007cites this paper
• Immunreaktivität von VEGF und Gravin in humanen Astrozytomen unterschiedlichen WHO-Grads

  2006cites this paper
• Immunreaktivität von VEGF und Gravin in humanen Astrozytomen unterschiedlichen WHO-Grads

  2006cites this paper
• Poor outcome of adult acute lymphoblastic leukemia patients carrying the (1;19)(q23;p13) translocation

  2006influential citation
• Structure of murine angiogenin: features of the substrate- and cell-binding regions and prospects for inhibitor-binding studies.

  2005cites this paper
• Endogenous angiogenin in endothelial cells is a general requirement for cell proliferation and angiogenesis

  2005cites this paper
• The ribonuclease A superfamily of mammals and birds: identifying new members and tracing evolutionary histories.

  2005cites this paper
• Angiogenin is translocated to the nucleus of HeLa cells and is involved in ribosomal RNA transcription and cell proliferation.

  2005cites this paper
• Cellular transformation of NIH3T3 fibroblasts by CIZ/NMP4 fusions

  2005cites this paper
• Oncogenes and tumor angiogenesis: the question of vascular "supply" and vascular "demand".

  2004cites this paper
• Oncogenes and Tumor Angiogenesis

  2004cites this paper
• Regeneration in MRL mice: further genetic loci controlling the ear hole closure trait using MRL and M.m. Castaneus mice

  2004cites this paper
• Angiogenins: a new class of microbicidal proteins involved in innate immunity

  2003cites this paper
• Pseudogenization of the tumor-growth promoter angiogenin in a leaf-eating monkey.

  2003cites this paper
• Pharmacological characterization of CP-547,632, a novel vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor for cancer therapy.

  2003cites this paper
• Activating Signal Cointegrator 2 Required for Liver Lipid Metabolism Mediated by Liver X Receptors in Mice

  2003cites this paper
• Clinical translation of angiogenesis inhibitors

  2002cites this paper
• Diversifying selection of the tumor-growth promoter angiogenin in primate evolution.

  2002influential citation
• Molecular analysis of commensal host-microbial relationships in the intestine.

  2001cites this paper
• The role of E2A-PBX1 in leukemogenesis

  2001cites this paper
• The leukemogenic transcription factor E2a-Pbx1 induces expression of the putative N-myc and p53 target gene NDRG1 in Ba/F3 cells

  2001cites this paper
• High-level expression of three members of the murine angiogenin family in Escherichia coli and purification of the recombinant proteins.

  2001cites this paper
• Oncogenes and angiogenesis: signaling three-dimensional tumor growth.

  2000cites this paper
• Influence of host microvascular environment on tumour vascular endothelium

  1999cites this paper