Deep Sequencing Analysis of Aptazyme Variants Based on a Pistol Ribozyme.

No abstract is available for this paper.

• Publication year

  2017

• Venue

  ACS Synthetic Biology

• Publication date

  2017-04-14

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1021/acssynbio.7b00057PMID 28398719
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Ligand‐dependent ribozymes

  2017cited by this paper
• Pistol ribozyme adopts a pseudoknot fold facilitating site-specific in-line cleavage

  2016cited by this paper
• Crystal structure of Pistol, a class of self-cleaving ribozyme

  2016cited by this paper
• Rational design of aptazyme riboswitches for efficient control of gene expression in mammalian cells

  2016cited by this paper
• Twister ribozymes as highly versatile expression platforms for artificial riboswitches

  2016cited by this paper
• High‐Throughput Mutational Analysis of a Twister Ribozyme

  2016cited by this paper
• Conditional control of mammalian gene expression by tetracycline-dependent hammerhead ribozymes.

  2015cited by this paper
• High-throughput assay and engineering of self-cleaving ribozymes by sequencing

  2015cited by this paper
• New classes of self-cleaving ribozymes revealed by comparative genomics analysis

  2015cited by this paper
• Biochemical analysis of pistol self-cleaving ribozymes

  2015cited by this paper
• Synthetic riboswitches - A tool comes of age.

  2014cited by this paper
• Controlling Mammalian Gene Expression by Allosteric Hepatitis Delta Virus Ribozymes

  2013cited by this paper
• NGS QC Toolkit: A Toolkit for Quality Control of Next Generation Sequencing Data

  2012cited by this paper
• Synthetic mammalian riboswitches based on guanine aptazyme.

  2012cited by this paper
• Kinetic analysis of aptazyme-regulated gene expression in a cell-free translation system: modeling of ligand-dependent and -independent expression.

  2012cited by this paper
• Riboswitches: structures and mechanisms.

  2011cited by this paper
• ViennaRNA Package 2.0

  2011cited by this paper
• Artificial ribozyme switches containing natural riboswitch aptamer domains.

  2009cited by this paper
• Biologically inspired synthetic enzymes made from DNA.

  2009cited by this paper
• Conditional RNA interference mediated by allosteric ribozyme.

  2009cited by this paper
• Improved aptazyme design and in vivo screening enable riboswitching in bacteria.

  2008cited by this paper
• An Artificial Aptazyme‐Based Riboswitch and its Cascading System in E. coli

  2008cited by this paper
• A modular and extensible RNA-based gene-regulatory platform for engineering cellular function

  2007cited by this paper
• WebLogo: a sequence logo generator.

  2004cited by this paper
• Riboswitches control fundamental biochemical pathways in Bacillus subtilis and other bacteria.

  2003cited by this paper
• A mechanistic framework for co-transcriptional folding of the HDV genomic ribozyme in the presence of downstream sequence.

  2002cited by this paper
• Reverse transcriptase template switching: a SMART approach for full-length cDNA library construction.

  2001cited by this paper
• A role for upstream RNA structure in facilitating the catalytic fold of the genomic hepatitis delta virus ribozyme.

  2000cited by this paper

• RNAGym: Large-scale Benchmarks for RNA Fitness and Structure Prediction

  2025cites this paper
• De Novo Development of Fluorogenic RNA-Based Biosensors Using Capture-SELEX in Tandem with Droplet Microfluidics.

  2025cites this paper
• NABench: Large-Scale Benchmarks of Nucleotide Foundation Models for Fitness Prediction

  2025cites this paper
• Deep generative model of RNAs based on variational autoencoder with context-free grammar

  2025cites this paper
• Identification of HDV-like theta ribozymes involved in tRNA-based recoding of gut bacteriophages

  2024cites this paper
• Development of an RNA virus-based episomal vector with artificial aptazyme for gene silencing

  2024cites this paper
• Fitness Landscapes and Evolution of Catalytic RNA.

  2024cites this paper
• Discovery of Theta Ribozymes in Gut Phages–Implications for tRNA and Alternative Genetic Coding

  2023cites this paper
• Method for Identifying Sequence Motifs in Pre-miRNAs for Small-Molecule Binding

  2022cites this paper
• High content design of riboswitch biosensors: All-around rational module-by-module design.

  2022cites this paper
• RNA sequence to structure analysis from comprehensive pairwise mutagenesis of multiple self-cleaving ribozymes

  2022cites this paper
• Chemical Modifications in Natural and Engineered Ribozymes

  2021cites this paper
• Computer-Aided Design of Active Pseudoknotted Hammerhead Ribozymes.

  2021cites this paper
• Aptazyme-Based Riboswitches and Logic Gates in Mammalian Cells.

  2021cites this paper
• Single-round deoxyribozyme discovery

  2021cites this paper
• Riboswitches for Controlled Expression of Therapeutic Transgenes Delivered by Adeno-Associated Viral Vectors

  2021cites this paper
• Circularly-Permuted Pistol Ribozyme: A Synthetic Ribozyme Scaffold for Mammalian Riboswitches.

  2021cites this paper
• Self-cleaving ribozymes: substrate specificity and synthetic biology applications

  2021cites this paper
• Elucidation of Ribozyme Mechanisms at the Example of the Pistol Ribozyme

  2021cites this paper
• Aptazyme-Based and in

  2021cites this paper
• USING FUNCTIONAL LINKS BETWEEN DISTINCT RNA ENZYMES TO GUIDE COMPUTATIONAL STUDIES AND UNCOVER BIOCATALYTIC STRATEGIES

  2021cites this paper
• High-Throughput Analysis and Engineering of Ribozymes and Deoxyribozymes by Sequencing.

  2020cites this paper
• Comprehensive sequence-to-function mapping of cofactor-dependent RNA catalysis in the glmS ribozyme

  2020cites this paper
• Phased nucleotide inserts for sequencing low-diversity RNA samples from in vitro selection experiments

  2020cites this paper
• High-throughput identification of synthetic riboswitches by barcode-free amplicon-sequencing in human cells

  2020cites this paper
• Aptamers in RNA-based switches of gene expression.

  2019cites this paper
• Molecular simulations of the pistol ribozyme: unifying the interpretation of experimental data and establishing functional links with the hammerhead ribozyme

  2019cites this paper
• Aptamer-based and aptazyme-based riboswitches in mammalian cells

  2019cites this paper
• Detection of Low-Abundance Metabolites in Live Cells Using an RNA Integrator.

  2019cites this paper
• Applications of high-throughput sequencing to analyze and engineer ribozymes.

  2019cites this paper
• Design of Mammalian ON-Riboswitches Based on Tandemly Fused Aptamer and Ribozyme.

  2019cites this paper
• Catalytic Nucleic Acids for Bioanalysis.

  2019cites this paper
• Using machine learning to predict quantitative phenotypes from protein and nucleic acid sequences

  2019influential citation
• Catalytic RNA, ribozyme, and its applications in synthetic biology.

  2019cites this paper
• Systematic minimization of RNA ligase ribozyme through large-scale design-synthesis-sequence cycles

  2019cites this paper
• Empirical Investigations OF RNA Fitness Landscapes: Harnessing the Power of High-Throughput Sequencing and Evolutionary Simulations

  2018cites this paper
• Analyzing and Tuning Ribozyme Activity by Deep Sequencing To Modulate Gene Expression Level in Mammalian Cells.

  2018cites this paper
• Direct screening for ribozyme activity in mammalian cells.

  2017cites this paper
• RNA-based dynamic genetic controllers: development strategies and applications

  2017cites this paper
• Large Scale Mutational and Kinetic Analysis of a Self-Hydrolyzing Deoxyribozyme.

  2017cites this paper
• RNAG YM : B ENCHMARKS FOR RNA F ITNESS AND S TRUCTURE P REDICTION

  year unknowncites this paper