Evaluation of Fetal Central Nervous System Anomalies by Ultrasound and Its Anatomical Co-relation.

INTRODUCTION Central nervous system anomalies are often severe and are the most common indications for therapeutic abortions. Ultrasound examination helps to identify and evaluate them well before birth. OBJECTIVES Present study was undertaken to evaluate the incidence of central nervous system anomalies in utero by ultrasound and to confirm them by autopsy or postnatal examination. METHOD Ultrasound screening of 7485 pregnant women was performed. Pregnancy with ultrasound findings of central nervous system anomalies were followed up. Prenatal ultrasound findings were confirmed by autopsy in cases of therapeutic abortions and fetal losses. In case of live birth postnatal findings were noted. RESULTS Ultrasound detected central nervous system malformations in 24 fetuses. Ultrasound findings were matching in 83% on autopsy. Autopsy and postnatal findings together were matching with ultrasound in 85.7%. Two cases had additional minor findings on autopsy. CONCLUSION The incidence of central nervous system malformations on ultrasound was 0.31%. Autopsy and postnatal examination showed high degree of correlation with ultrasound findings.

• Publication year

  2014

• Venue

  Journal of clinical and diagnostic research : JCDR

• Publication date

  2014-06-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.7860/JCDR/2014/8052.4437PMID 25120962PMCID PMC4129269
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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