Synthesizing Risk from Summary Evidence Across Multiple Risk Factors.

Although meta-analyses provide summary effect estimates that help advise patient care, patients often want to compare their overall health to the general population. The Harvard Cancer Risk Index was published in 2004 and uses risk ratio estimates and prevalence estimates from original studies across many risk factors to provide an answer to this question. However, the published version of the formula only uses dichotomous risk factors and its derivation was not provided. The objective of this brief report was to provide the derivation of a more general form of the equation that allows the incorporation of risk factors with three or more levels.

• Publication year

  2018

• Venue

  Epidemiology

• Publication date

  2018-07-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1097/EDE.0000000000000820PMID 29537993
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• A Cluster Randomized Trial of a Personalized Multi-Condition Risk Assessment in Primary Care.

  2017cited by this paper
• A Simple Tool for Communicating the Benefits and Harms of Health Interventions

  2016cited by this paper
• Validation of a risk prediction tool for coronary heart disease in middle-aged women

  2015cited by this paper
• [The Dutch Cancer Society Cancer Risk Test].

  2012cited by this paper
• Validation of the Harvard Cancer Risk Index: a prediction tool for individual cancer risk.

  2004cited by this paper

• No citing papers are available for this paper.