Pulmonary surfactant protein SP‐B promotes exocytosis of lamellar bodies in alveolar type II cells

No abstract is available for this paper.

• Publication year

  2018

• Venue

  The FASEB Journal

• Publication date

  2018-03-15

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1096/fj.201701462RRPMID 29543530
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• ATP is stored in lamellar bodies to activate vesicular P2X4 in an autocrine fashion upon exocytosis

  2018cited by this paper
• Pulmonary surfactant metabolism in the alveolar airspace: Biogenesis, extracellular conversions, recycling.

  2017cited by this paper
• A small key unlocks a heavy door: The essential function of the small hydrophobic proteins SP-B and SP-C to trigger adsorption of pulmonary surfactant lamellar bodies.

  2016cited by this paper
• An improved method for isolating type II cells in high yield and purity.

  2015cited by this paper
• Composition, structure and mechanical properties define performance of pulmonary surfactant membranes and films.

  2015cited by this paper
• A model for the structure and mechanism of action of pulmonary surfactant protein B

  2015cited by this paper
• Structure-function relationships in pulmonary surfactant membranes: from biophysics to therapy.

  2014cited by this paper
• Role of Pannexin-1 hemichannels and purinergic receptors in the pathogenesis of human diseases

  2014cited by this paper
• A new role for P2X4 receptors as modulators of lung surfactant secretion

  2013cited by this paper
• Segregated ordered lipid phases and protein-promoted membrane cohesivity are required for pulmonary surfactant films to stabilize and protect the respiratory surface.

  2013cited by this paper
• Topology and lipid selectivity of pulmonary surfactant protein SP-B in membranes: Answers from fluorescence.

  2012cited by this paper
• Fiji: an open-source platform for biological-image analysis

  2012influential reference
• Spatio-temporal aspects, pathways and actions of Ca(2+) in surfactant secreting pulmonary alveolar type II pneumocytes.

  2012cited by this paper
• ATP released from cardiac fibroblasts via connexin hemichannels activates profibrotic P2Y2 receptors

  2012cited by this paper
• Interfacial sensing by alveolar type II cells: a new concept in lung physiology?

  2011cited by this paper
• Rho Signaling Regulates Pannexin 1-mediated ATP Release from Airway Epithelia*

  2011cited by this paper
• Lung Surfactant Protein A (SP-A) Interactions with Model Lung Surfactant Lipids and an SP-B Fragment

  2011cited by this paper
• Extracellular ATP acts on P2Y2 purinergic receptors to facilitate HIV-1 infection

  2011cited by this paper
• Cell deformation at the air-liquid interface induces Ca2+-dependent ATP release from lung epithelial cells.

  2011cited by this paper
• Combined and independent action of proteins SP-B and SP-C in the surface behavior and mechanical stability of pulmonary surfactant films.

  2010cited by this paper
• Pulmonary surfactant layers accelerate O(2) diffusion through the air-water interface.

  2010cited by this paper
• Existence of exocytotic hemifusion intermediates with a lifetime of up to seconds in type II pneumocytes.

  2009cited by this paper
• Surfactant protein SP-B strongly modifies surface collapse of phospholipid vesicles: insights from a quartz crystal microbalance with dissipation.

  2009cited by this paper
• Structure of pulmonary surfactant membranes and films: the role of proteins and lipid-protein interactions.

  2008cited by this paper
• Mapping and analysis of the lytic and fusogenic domains of surfactant protein B.

  2005cited by this paper
• Paracrine stimulation of surfactant secretion by extracellular ATP in response to mechanical deformation.

  2005cited by this paper
• Inactivation of pulmonary surfactant due to serum-inhibited adsorption and reversal by hydrophilic polymers: experimental.

  2005cited by this paper
• Tracing surfactant transformation from cellular release to insertion into an air-liquid interface.

  2004cited by this paper
• Ca2+ entry is essential for cell strain-induced lamellar body fusion in isolated rat type II pneumocytes.

  2004cited by this paper
• Biogenesis of lamellar bodies, lysosome-related organelles involved in storage and secretion of pulmonary surfactant.

  2002cited by this paper
• Regulation of surfactant secretion.

  2001cited by this paper
• Secretion in alveolar type II cells at the interface of constitutive and regulated exocytosis.

  2001cited by this paper
• [Ca(2+)](i) oscillations regulate type II cell exocytosis in the pulmonary alveolus.

  2000cited by this paper
• Differential effects of surfactant protein A on regional organization of phospholipid monolayers containing surfactant protein B or C.

  2000cited by this paper
• Surfactant protein A regulates pulmonary surfactant secretion via activation of phosphatidylinositol 3-kinase in type II alveolar cells.

  2000cited by this paper
• Microstructure and dynamic surface properties of surfactant protein SP-B/dipalmitoylphosphatidylcholine interfacial films spread from lipid-protein bilayers

  2000cited by this paper
• Threshold calcium levels for lamellar body exocytosis in type II pneumocytes.

  1999cited by this paper
• Threshold calcium levels for lamellar body exocytosis in type II pneumocytes.

  1999cited by this paper
• Surfactant subtype conversion is related to loss of surfactant apoprotein B and surface activity in large surfactant aggregates. Experimental and clinical studies.

  1999cited by this paper
• Depth profiles of pulmonary surfactant protein B in phosphatidylcholine bilayers, studied by fluorescence and electron spin resonance spectroscopy.

  1998cited by this paper
• Dynamics of surfactant release in alveolar type II cells.

  1998cited by this paper
• Surface properties, morphology and protein composition of pulmonary surfactant subtypes.

  1996cited by this paper
• Interactions of hydrophobic lung surfactant proteins SP-B and SP-C with dipalmitoylphosphatidylcholine and dipalmitoylphosphatidylglycerol bilayers studied by electron spin resonance spectroscopy.

  1995cited by this paper
• Surfactant subtypes. In vitro conversion, in vivo function, and effects of serum proteins.

  1994cited by this paper
• Degradation of surfactant-associated protein B (SP-B) during in vitro conversion of large to small surfactant aggregates.

  1993cited by this paper
• Solubility of hydrophobic surfactant proteins in organic solvent/water mixtures. Structural studies on SP-B and SP-C in aqueous organic solvents and lipids.

  1993cited by this paper
• Surfactant protein A-binding proteins. Characterization and structures.

  1993cited by this paper
• Pulmonary surfactant-associated protein SP-B has little effect on acyl chains in dipalmitoylphosphatidylcholine dispersions.

  1993cited by this paper
• Secondary structure and orientation of the surfactant protein SP-B in a lipid environment. A Fourier transform infrared spectroscopy study.

  1992cited by this paper
• Calcium mobilization and exocytosis after one mechanical stretch of lung epithelial cells.

  1990cited by this paper
• Pulmonary surfactant and its components inhibit secretion of phosphatidylcholine from cultured rat alveolar type II cells.

  1987cited by this paper
• Surfactant-associated protein inhibits phospholipid secretion from type II cells.

  1987cited by this paper
• The pulmonary consequences of a deep breath.

  1982cited by this paper
• A rapid method of total lipid extraction and purification.

  1959cited by this paper

• Protein biomarkers of interstitial lung abnormalities in relatives of patients with pulmonary fibrosis

  2025cites this paper
• Immunological and regenerative properties of lung stem cells.

  2025cites this paper
• Pulmonary surfactant in asthma.

  2025cites this paper
• Surfactant protein SP-B: one ring to rule the molecular and biophysical mechanisms of the pulmonary surfactant system

  2025cites this paper
• Surfactant protein B-derived peptides as endosomal escape enhancers for pulmonary delivery of siRNA.

  2025cites this paper
• LRRK2 is involved in heat exposure-induced acute lung injury and alveolar type II epithelial cell dysfunction.

  2024cites this paper
• Activated DRP1 promotes mitochondrial fission and induces glycolysis in ATII cells under hyperoxia

  2024cites this paper
• Factors influencing airway smooth muscle tone: A comprehensive review with a special emphasis on pulmonary surfactant.

  2024cites this paper
• Evaluating Novel SP-B and SP-C Synthetic Analogues for Pulmonary Surfactant Efficacy

  2024cites this paper
• Molecular Impact of Conventional and Electronic Cigarettes on Pulmonary Surfactant

  2023cites this paper
• Pulmonary Surfactant: A Mighty Thin Film.

  2023cites this paper
• Fluid Interfaces as Models for the Study of Lipid-Based Films with Biophysical Relevance

  2023cites this paper
• Serum metabolic signatures for acute pulmonary embolism identified by untargeted metabolomics

  2023cites this paper
• The interaction and orientation of Peptide KL4 in model membranes.

  2022cites this paper
• The Proteomic Profile of Interstitial Lung Abnormalities.

  2022cites this paper
• Changes in CSF Surface Tension in Relation to Surfactant Proteins in Children with Intraventricular Hemorrhage

  2022cites this paper
• Molecular Pathogenesis of Fibrosis, Thrombosis and Surfactant Dysfunction in the Lungs of Severe COVID-19 Patients

  2022cites this paper
• Pannexin-1 channel opening is critical for COVID-19 pathogenesis

  2021cites this paper
• Pulmonary surfactant: a unique biomaterial with life-saving therapeutic applications.

  2021cites this paper
• Simulated Breathing: Application of Molecular Dynamics Simulations to Pulmonary Lung Surfactant

  2021cites this paper
• The Significance of KL-6 as Prognosis Monitoring Biomarker in Patients With Severe COVID-19 From Stabilized Stage Toward Convalescence

  2021cites this paper
• Increased Alveolar Heparan Sulphate and Reduced Pulmonary Surfactant Amount and Function in the Mucopolysaccharidosis IIIA Mouse

  2021cites this paper
• Structural hallmarks of lung surfactant: Lipid-protein interactions, membrane structure and future challenges.

  2021cites this paper
• Surfactant Protein B Promotes Cytosolic SiRNA Delivery by Adopting a Virus-like Mechanism of Action.

  2021cites this paper
• Potential Therapeutic Applications of Pulmonary Surfactant Lipids in the Host Defence Against Respiratory Viral Infections

  2021cites this paper
• Compositional, structural and functional properties of discrete coexisting complexes within bronchoalveolar pulmonary surfactant.

  2021cites this paper
• Pulmonary Surfactant Lipid Reorganization Induced by the Adsorption of the Oligomeric Surfactant Protein B Complex.

  2020influential citation
• Pulmonary siRNA delivery for lung disease: Review of recent progress and challenges.

  2020cites this paper
• Lipid–Protein and Protein–Protein Interactions in the Pulmonary Surfactant System and Their Role in Lung Homeostasis

  2020influential citation
• Pulmonary surfactant protein SP-B nanorings induce the multilamellar organization of surfactant complexes.

  2020cites this paper
• Hydroxychloroquine can potentially interfere with immune function in COVID-19 patients: Mechanisms and insights

  2020cites this paper
• Mechanism of IL-8-induced acute lung injury through pulmonary surfactant proteins A and B

  2019cites this paper
• Native supramolecular protein complexes in pulmonary surfactant: Evidences for SP-A/SP-B interactions.

  2019cites this paper
• Pulmonary surfactant and drug delivery: Focusing on the role of surfactant proteins

  2018cites this paper