Sro7p, a Saccharomyces cerevisiae counterpart of the tumor suppressor l(2)gl protein, is related to myosins in function.

No abstract is available for this paper.

• Publication year

  1998

• Venue

  Genetics

• Publication date

  1998-08-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1093/GENETICS/149.4.1717PMID 9691031PMCID PMC1460282
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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• Myosins in yeast.

  1997cited by this paper
• High Rates of Actin Filament Turnover in Budding Yeast and Roles for Actin in Establishment and Maintenance of Cell Polarity Revealed Using the Actin Inhibitor Latrunculin-A

  1997influential reference
• SRO9, a multicopy suppressor of the bud growth defect in the Saccharomyces cerevisiae rho3-deficient cells, shows strong genetic interactions with tropomyosin genes, suggesting its role in organization of the actin cytoskeleton.

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• Genetic analysis of the Saccharomyces cerevisiae RHO3 gene, encoding a rho-type small GTPase, provides evidence for a role in bud formation.

  1996cited by this paper
• The human homologue of the murine Llglh gene (LLGL) maps within the Smith-Magenis syndrome region in 17p11.2.

  1996cited by this paper
• Yeast src homology region 3 domain-binding proteins involved in bud formation

  1996cited by this paper
• A human homologue of the Drosophila tumour suppressor gene l(2)gl maps to 17p11.2-12 and codes for a cytoskeletal protein that associates with nonmuscle myosin II heavy chain.

  1995cited by this paper
• Sec6, Sec8, and Sec15 are components of a multisubunit complex which localizes to small bud tips in Saccharomyces cerevisiae

  1995cited by this paper
• The Drosophila lethal(2)giant larvae tumor suppressor protein is a component of the cytoskeleton

  1994cited by this paper
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  1994cited by this paper
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  1994influential reference
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  1994cited by this paper
• The yeast TEM1 gene, which encodes a GTP-binding protein, is involved in termination of M phase

  1994cited by this paper
• A mouse homologue of the Drosophila tumour-suppressor gene l(2)gl controlled by Hox-C8 in vivo

  1993cited by this paper
• Cytokinesis.

  1992cited by this paper
• Yeast RHO3 and RHO4 ras superfamily genes are necessary for bud growth, and their defect is suppressed by a high dose of bud formation genes CDC42 and BEM1

  1992influential reference
• Isolation and characterization of two novel ras superfamily genes in Saccharomyces cerevisiae.

  1992influential reference
• A yeast gene (BEM1) necessary for cell polarization whose product contains two SH3 domains

  1992cited by this paper
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  1991influential reference
• Yeast CAL1 is a structural and functional homologue to the DPR1 (RAM) gene involved in ras processing.

  1991cited by this paper
• CDC42 and CDC43, two additional genes involved in budding and the establishment of cell polarity in the yeast Saccharomyces cerevisiae

  1990cited by this paper
• Yeast myosin heavy chain mutant: maintenance of the cell type specific budding pattern and the normal deposition of chitin and cell wall components requires an intact myosin heavy chain gene.

  1990cited by this paper
• Fluorescence microscopy methods for yeast.

  1989cited by this paper
• A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae.

  1989influential reference
• New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites.

  1988cited by this paper
• The yeast MYO1 gene encoding a myosin‐like protein required for cell division.

  1987influential reference
• A ras-like protein is required for a post-Golgi event in yeast secretion.

  1987cited by this paper
• Production of single-stranded plasmid DNA.

  1987cited by this paper
• Identification of myosin heavy chain in Saccharomyces cerevisiae

  1985cited by this paper
• Transformation of intact yeast cells treated with alkali cations.

  1984cited by this paper
• Transformation of intact yeast cells treated with alkali cations

  1983cited by this paper
• Localized secretion of acid phosphatase reflects the pattern of cell surface growth in saccharomyces cerevisiae

  1980cited by this paper
• Methods in yeast genetics

  1979cited by this paper
• Malignant neoplasms of genetic origin in Drosophila melanogaster.

  1978cited by this paper
• Wall replication in saccharomyces species: use of fluorescein-conjugated concanavalin A to reveal the site of mannan insertion.

  1972cited by this paper

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  2020cites this paper
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  2019cites this paper
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  2017cites this paper
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  2016cites this paper
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  2015cites this paper
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  2015cites this paper
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  2015cites this paper
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  2015cites this paper
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  2015cites this paper
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  2011cites this paper
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  2011cites this paper
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  2011cites this paper
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  2011cites this paper
• Establishing cell polarity by the Lgl family proteins

  2010cites this paper
• Functional characterisation of the yeast tumour suppressor homologue Sro7p

  2009influential citation
• Friends and foes in synaptic transmission: the role of tomosyn in vesicle priming.

  2009cites this paper
• Phylogeny of the SNARE vesicle fusion machinery yields insights into the conservation of the secretory pathway in fungi

  2009cites this paper
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  2009cites this paper
• Cloning and characterization of the promoter of Hugl-2, the human homologue of Drosophila lethal giant larvae (lgl) polarity gene.

  2008cites this paper
• Signaling networks during development: the case of asymmetric cell division in the Drosophila nervous system.

  2008cites this paper
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  2008cites this paper
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• Spatial regulation of exocytosis and cell polarity: Yeast as a model for animal cells

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  2001cites this paper
• Cell polarity: squaring the circle.

  2001cites this paper
• A protein interaction map for cell polarity development

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  2001influential citation
• Epithelial cell polarity and cell junctions in Drosophila.

  2001cites this paper
• PDZ proteins and polarity: functions from the fly.

  2001cites this paper
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  1999influential citation
• Yeast Stress Responses

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