Contribution of the pancreas to circulating somatostatin-like immunoreactivity in the normal dog.

No abstract is available for this paper.

• Publication year

  1984

• Venue

  Journal of Clinical Investigation

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1172/JCI111194PMID 6140271PMCID PMC425002
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Extraction of somatostatin by the pancreas.

  1983cited by this paper
• High somatostatin uptake by the isolated perfused dog pancreas consistent with "insulo-acinar" axis.

  1982cited by this paper
• Somatostatin-14 and -28: clearance and potency on gastric function in dogs.

  1982cited by this paper
• Adrenergic control of somatostatin release.

  1982cited by this paper
• The nature of big plasma somatostatin: implications for the measurement of somatostatin-like immunoreactivity in human plasma.

  1982cited by this paper
• New Perspectives on the Microvasculature of the Islets of Langerhans in the Rat

  1982cited by this paper
• Evidence for the Presence of Somatostatin 28 in Plasma

  1982cited by this paper
• Multiple forms of immunoreactive somatostatin: comparison of distribution in neural and nonneural tissues and portal plasma of the rat.

  1981cited by this paper
• Reversal of Increased Gastric Somatostatin in Streptozotocin-diabetic Rats by Whole Pancreas Transplantation

  1981cited by this paper
• Synthesis of one form of pancreatic islet somatostatin predominates.

  1981cited by this paper
• Concentration and Secretion of Gastric Somatostatin in Streptozotocin-diabetic Rats

  1981cited by this paper
• Radioimmunoassay study of hepatic clearance and disappearance half-time of somatostatin and vasoactive intestinal peptide in dogs.

  1981cited by this paper
• Origin of peripheral venous hypersomatostatinemia in alloxan-diabetic dogs.

  1981cited by this paper
• Hepatic and renal metabolism of somatostatin-like immunoreactivity. Simultaneous assessment in the dog.

  1981cited by this paper
• Abnormalities of Pancreatic Somatostatin Secretion Corrected by In Vivo Insulin Treatment of Streptozotocin-Diabetic Rats

  1981cited by this paper
• Characterisation of the abnormal pancreatic D and A cell function in streptozotocin diabetic dogs: Studies with D-glyceraldehyde, dihydroxyacetone, D-mannoheptulose, D-glucose, and L-arginine

  1981cited by this paper
• Clearance of immunoreactive somatostatin by perfused rat liver.

  1981cited by this paper
• Heterogeneity of somatostatin-like peptides in rat brain, pancreas, and gastrointestinal tract.

  1981cited by this paper
• Somatostatin Release from the Isolated, Perfused Diabetic Rat Pancreas: Inverse Relationship Between Pancreatic Somatostatin and Insulin

  1980cited by this paper
• Blood flow to the rabbit pancreas with special reference to the islets of langerhans

  1980cited by this paper
• Blood flow to the rabbit pancreas with special reference to the islets of Langerhans.

  1980cited by this paper
• Increased blood somatostatin concentration in streptozotocin diabetic rats.

  1980cited by this paper
• Adrenergic modulation of gastric somatostatin release in rats

  1980cited by this paper
• Somatostatin Concentration Responds to Arginine in Portal Plasma: Effects of Fasting, Streptozotocin Diabetes, and Insulin Administration in Diabetic Rats

  1980cited by this paper
• Reversal of the Enhanced Somatostatin Release from the Isolated, Perfused Diabetic Rat Pancreas after the Amelioration of Diabetes by Whole Pancreas Transplantation

  1980cited by this paper
• Adrenergic modulation of pancreatic A, B, and D cells alpha-Adrenergic suppression and beta-adrenergic stimulation of somatostatin secretion, alpha-adrenergic stimulation of glucagon secretion in the perfused dog pancreas.

  1979cited by this paper
• Half-life of somatostatin-like immunoreactivity in canine plasma.

  1979cited by this paper
• Plasma somatostatin-like immunoreactivity in depancreatized dogs.

  1979cited by this paper
• Pancreatic and gastric release of somatostatinlike immunoreactivity during intestinal phase of a meal.

  1979cited by this paper
• Reduction in Portal Vein Blood Flow by Somatostatin

  1979cited by this paper
• Differential effects of somatostatin analogues on alpha- and beta-cells of the pancreas.

  1979cited by this paper
• Regional Distribution and Concentration of Pancreatic Polypeptide in the Human and Canine Pancreas

  1978cited by this paper
• Gastrointestinal somatostatin: extraction and radioimmunoassay in different species.

  1978cited by this paper
• Current concepts of neuro-hormonal control of pancreatic secretion

  1978cited by this paper
• Changes in somatostatin concentration in pancreas and other tissues of streptozotocin diabetic rats.

  1978cited by this paper
• Pancreatic and gastric somatostatin release in response to intragastric and intraduodenal nutrients and HCl in the dog.

  1978cited by this paper
• Characterization of proinsulin-insulin intermediates in human plasma.

  1978cited by this paper
• The effects of gastrin, gastric inhibitory polypeptide, secretin, and the octapeptide of cholecystokinin upon immunoreactive somatostatin release by the perfused canine pancreas.

  1977cited by this paper
• Immunoreactive somatostatin levels in plasma of normal and alloxan diabetic dogs

  1977cited by this paper
• Somatostatin: abundance of immunoreactive hormone in rat stomach and pancreas.

  1975cited by this paper
• Immunoreactive somatostatin is present in discrete cells of the endocrine pancreas.

  1975cited by this paper
• Neural regulation of insulin secretion in the dog.

  1973cited by this paper
• Immunoassay of Insulin: Two Antibody System: Plasma Insulin Levels of Normal, Subdiabetic and Diabetic Rats

  1963cited by this paper

• Pharmacologic inhibition of somatostatin receptor 2 to restore glucagon counterregulation in diabetes

  2024cites this paper
• Islet cilia and glucose homeostasis

  2022cites this paper
• KATP channel blockers control glucagon secretion by distinct mechanisms: A direct stimulation of α-cells involving a [Ca2+]c rise and an indirect inhibition mediated by somatostatin

  2021cites this paper
• Gap junction coupling and islet delta-cell function in health and disease.

  2021cites this paper
• Paracrine regulation of insulin secretion

  2020cites this paper
• Regulation of Pancreatic Exocrine Function by Islet Hormones

  2020cites this paper
• Intra-Pancreatic Insulin Nourishes Cancer Cells: Do Insulin-Receptor Antagonists such as PGG and EGCG Play a Role?

  2020cites this paper
• Regulation of docking and priming in pancreatic α- and β-cells

  2019cites this paper
• The Difference δ-Cells Make in Glucose Control.

  2018cites this paper
• The somatostatin-secreting pancreatic δ-cell in health and disease

  2018cites this paper
• The somatostatin-secreting pancreatic δ-cell in and disease.

  2018cites this paper
• The Difference Delta Cells Make in Glucose Control

  2018cites this paper
• δ-Cells Make in Glucose Control.

  2018cites this paper
• Somatostatin Is Only Partly Required for the Glucagonostatic Effect of Glucose but Is Necessary for the Glucagonostatic Effect of KATP Channel Blockers

  2018cites this paper
• Relations intercellulaires dans les îlots de Langerhans et leur rôle dans la sécrétion du glucagon

  2017cites this paper
• Somatostatin: One of the Rare Multifunctional Inhibitors of Mammalian Species.

  2017influential citation
• Somatostatin Receptor Type 2 Antagonism Improves Glucagon Counterregulation in Biobreeding Diabetic Rats

  2013cites this paper
• A genetic association between ß3-aderenoceptor and cholinergic receptor muscarinic 3 polymorphisms in irritable bowel syndrome.

  2011cites this paper
• Dose-response effect of a beta3-adrenergic receptor agonist, solabegron, on gastrointestinal transit, bowel function, and somatostatin levels in health.

  2008cites this paper
• Function and expression of somatostatin receptors of the endocrine pancreas.

  2008cites this paper
• Dose-response effect of a 3-adrenergic receptor agonist , solabegron , on gastrointestinal transit , bowel function , and somatostatin levels in health April

  2008cites this paper
• Demonstration of functional neuronal beta3-adrenoceptors within the enteric nervous system.

  2007cites this paper
• Somatostatin Response in and Gastrectomized Subjects

  2006cites this paper
• Production, Action, and Degradation of Somatostatin

  2001cites this paper
• Insulin and Glucagon Secretion in vivo and its Neural Control

  2001cites this paper
• Sepsis‐induced Changes in Pancreatic Hormone Secretion

  2001cites this paper
• Antazoline increases insulin secretion and improves glucose tolerance in rats and dogs.

  1997cites this paper
• The islet-acinar axis of the pancreas

  1994cites this paper
• Cholecystokinin type A receptors mediate intestinal fat-induced inhibition of acid secretion through somatostatin-14 in dogs.

  1994cites this paper
• In Vivo and in Vitro Effects of Adenosine‐5′‐0‐(2‐thiodiphosphate) on Pancreatic Hormones in Dogs

  1994cites this paper
• Differential processing of regulatory peptide precursors in pancreas and gut: studies of proglucagon and prosomatostatin processing.

  1994cites this paper
• Differential neural regulation of circulating somatostatin-14 and somatostatin-28 in conscious dogs.

  1993cites this paper
• Role of somatostatin in glucose regulation during endotoxicosis in the rat.

  1993cites this paper
• Regulation of somatostatin-14 and -28 secretion by gastric acid in dogs: differential role of cholecystokinin.

  1993cites this paper
• Sympathoadrenal system in neuroendocrine control of glucose: mechanisms involved in the liver, pancreas, and adrenal gland under hemorrhagic and hypoglycemic stress.

  1992cites this paper
• Influence of gastric acid on circulating somatostatin-14 and -28 released after insulin-induced hypoglycemia in conscious dogs.

  1992cites this paper
• The Physiological Role of Somatostatin in the Regulation of Nutrient Homeostasis

  1992cites this paper
• Effect of diabetes on in vivo and in vitro hypothalamic somatostatin release.

  1992cites this paper
• Effects of cholecystokinin (CCK)-8, CCK-33, and gastric inhibitory polypeptide (GIP) on basal and meal-stimulated pancreatic hormone secretion in man.

  1991cites this paper
• Neural control of islet function by norepinephrine and sympathetic neuropeptides.

  1991cites this paper
• The role of gastric inhibitory polypeptide in the regulation of pancreatic endocrine secretion

  1991cites this paper
• Neuroendocrine mechanisms involved in regulation of body weight, food intake and metabolism.

  1990cites this paper
• Effects of galanin and calcitonin gene-related peptide on insulin and glucagon secretion in man.

  1990cites this paper
• Mechanism of sympathetic neural regulation of insulin, somatostatin, and glucagon secretion.

  1990cites this paper
• Gastrin releasing peptide stimulates the secretion of insulin, but not that of glucagon or somatostatin, from the isolated perfused dog pancreas.

  1990cites this paper
• Hypersensitivity to arginine of both B and D pancreatic cells in adult streptozotocin-diabetic rats.

  1989cites this paper
• Relationship between gastric acid and elevated plasma somatostatinlike immunoreactivity after a mixed meal.

  1989cites this paper
• Biochemistry and physiology of gastrointestinal somatostatin

  1989cites this paper
• Impaired somatostatin response to orally administered glucose in type II diabetes entails both somatostatin-28 and -14 and is associated with deranged metabolic control.

  1989cites this paper
• Circulating prosomatostatin-derived peptides. Differential responses to food ingestion.

  1989cites this paper
• The Role of Dietary Starches and Sugars and Their Digestive End Products on Gastrointestinal Hormone Release

  1989cites this paper
• Circulation of the pancreas and salivary glands

  1989cites this paper
• Differential Responses to Food Ingestion

  1989cites this paper
• Effect of truncated glucagon-like peptide-1 [proglucagon-(78-107) amide] on endocrine secretion from pig pancreas, antrum, and nonantral stomach.

  1988cites this paper
• Modulatory effect of glucose on VIP-induced gastric somatostatin release.

  1988cites this paper
• Somatostatin response to glucose before and after prolonged fasting in lean and obese non-diabetic subjects.

  1988cites this paper
• Effect of vagotomy and atropine on plasma somatostatin response to a meal in conscious dogs.

  1988cites this paper
• The effects of epinephrine on islet hormone secretion in the dog

  1988cites this paper
• Nonadrenergic sympathetic neural influences on basal pancreatic hormone secretion.

  1988cites this paper
• Cholecystokinin (CCK)‐4 and CCK‐8 Stimulate Islet Hormone Secretion in Vivo in the Pig

  1988cites this paper
• Somatostatin-28 does not regulate islet function in the dog.

  1988cites this paper
• Effects of calcitonin gene-related peptide (CGRP) on islet hormone secretion in the pig

  1987cites this paper
• In Vivo Study of Glucose‐Induced Somatostatin Secretion: Comparison in Normal and Alloxan‐Diabetic Dogs

  1987cites this paper
• Sympathetic nerve stimulation versus pancreatic norepinephrine infusion in the dog: 2). Effects on basal release of somatostatin and pancreatic polypeptide.

  1987cites this paper
• Halothane anesthesia does not suppress sympathetic activation produced by neuroglucopenia.

  1987cites this paper
• Role of pancreatic somatostatin in determining glucagon response to arginine and morphine.

  1987cites this paper
• Evidence for Paracrine Function of Somatostatin

  1987cites this paper
• Differential alterations of the circulating prosomatostatin-derived peptides during insulin-induced hypoglycemia in man.

  1987cites this paper
• Calcitonin gene-related peptide: a potent and selective stimulator of gastrointestinal somatostatin secretion.

  1987cites this paper
• The presence and actions of NPY in the canine endocrine pancreas.

  1987cites this paper
• Hypersecretion of Gastric Somatostatin in Spontaneously Diabetic BB Rats

  1987cites this paper
• The mechanism of vagal nerve stimulation of glucagon and insulin secretion in the dog.

  1986cites this paper
• Plasma somatostatin and plasma glucagon in long-term IDDM without residual B-cell function. No effect of different long-term metabolic control.

  1986cites this paper
• [Somatostatin and regulation of the secretion of growth hormone].

  1986cites this paper
• Galanin: a novel pancreatic neuropeptide.

  1986cites this paper
• Plasma somatostatin response in normal and gastrectomized subjects.

  1986cites this paper
• Effects of insulin on fasting and meal-stimulated somatostatin-like immunoreactivity in noninsulin-dependent diabetes mellitus: evidence for more than one mechanism of action.

  1986cites this paper
• Effect of exocrine pancreatic secretagogues on circulating somatostatin in dogs.

  1986cites this paper
• Presence of somatostatin-like immunoreactivity in rat pancreatic juice: a physiological phenomenon.

  1986cites this paper
• Induction and management of diabetes mellitus in the pig.

  1986cites this paper
• Effect and mechanism of vagal nerve stimulation on somatostatin secretion in dogs.

  1986cites this paper
• Endogenous opioid modulation of pancreatic hormone secretion: studies in dogs.

  1986cites this paper
• Regulation of peripheral plasma somatostatin like immunoreactivity in type I diabetes: role of the degree of metabolic control.

  1986cites this paper
• Central Nervous System Control of Nutrient Homeostasis

  1986cites this paper
• Plasma somatostatin-like immunoreactivity responses to a mixed meal and the heterogeneity in healthy and non-insulin-dependent (NIDDM) diabetics.

  1986cites this paper
• Effect of CCK-8 on basal and meal-stimulated somatostatin in the baboon.

  1986cites this paper
• Neuropeptidergic versus cholinergic and adrenergic regulation of islet hormone secretion

  1986cites this paper
• Caerulein and secretin induced pancreatic growth: a possible control by endogenous pancreatic somatostatin.

  1985cites this paper
• Regulation of somatostatin secretion in man: study of the role of free fatty acids and ketone bodies.

  1984cites this paper
• Somatostatin in epithelial cells of intestinal mucosa is present primarily as somatostatin 28.

  1984cites this paper