Autoimmune Diabetes-Transgenic Nonobese Diabetic Mice from α Class II Molecule That Protects E , the MHCg 7 A Peptide Binding Motif for I-E

No abstract is available for this paper.

• Publication year

  1999

• Venue

  Unknown venue

• Publication date

  Unknown publication date

• Fields of study

  Not labeled

• Identifiers

  No identifiers available.

• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• Prevention of diabetes in NOD mice by a mutated I-Ab transgene.

  1998cited by this paper
• Do heat shock proteins control the balance of T-cell regulation in inflammatory diseases?

  1998cited by this paper
• A Mechanism for the Major Histocompatibility Complex–linked Resistance to Autoimmunity

  1997cited by this paper
• Molecular characterization of the diabetes-associated mouse MHC class II protein, I-Ag7.

  1997cited by this paper
• A Peptide-binding Motif for I-Ag7, the Class II Major Histocompatibility Complex (MHC) Molecule of NOD and Biozzi AB/H Mice

  1997cited by this paper
• Major Histocompatibility Complex–linked Control of Autoimmunity

  1997cited by this paper
• Deviation of pancreas‐infiltrating cells to Th2 by interleukin‐12 antagonist administration inhibits autoimmune diabetes

  1997cited by this paper
• Quantitative thresholds of MHC class II I-E expressed on hemopoietically derived antigen-presenting cells in transgenic NOD/Lt mice determine level of diabetes resistance and indicate mechanism of protection.

  1996cited by this paper
• Structures of an MHC Class II Molecule with Covalently Bound Single Peptides

  1996influential reference
• Natural ligand motifs of H-2E molecules are allele specific and illustrate homology to HLA-DR molecules.

  1995influential reference
• Genetic control of autoimmune diabetes in the NOD mouse.

  1995cited by this paper
• Self peptides isolated from MHC glycoproteins of non-obese diabetic mice.

  1994cited by this paper
• Following a diabetogenic T cell from genesis through pathogenesis.

  1993cited by this paper
• Immune response to glutamic acid decarboxylase correlates with insulitis in non-obese diabetic mice

  1993cited by this paper
• An Abd transgene prevents diabetes in nonobese diabetic mice by inducing regulatory T cells.

  1993cited by this paper
• Determinant capture as a possible mechanism of protection afforded by major histocompatibility complex class II molecules in autoimmune disease

  1993cited by this paper
• The murine autoimmune diabetes model: NOD and related strains.

  1992influential reference
• Functional analysis of DR17(DR3)-restricted mycobacterial T cell epitopes reveals DR17-binding motif and enables the design of allele-specific competitor peptides.

  1992cited by this paper
• MHC class-II molecules and autoimmunity.

  1991cited by this paper
• An explanation for the protective effect of the MHC class II I–E molecule in murine diabetes

  1991cited by this paper
• Characterization of pancreatic islet cell infiltrates in NOD mice: effect of cell transfer and transgene expression

  1991cited by this paper
• MHC-linked protection from diabetes dissociated from clonal deletion of T cells.

  1990influential reference
• Prevention of insulin-dependent diabetes mellitus in non-obese diabetic mice by transgenes encoding modified I-A beta-chain or normal I-E alpha-chain.

  1990cited by this paper
• A Unified Hypothesis for the Complex Genetics of HLA Associations With IDDM

  1990cited by this paper
• Prevention of insulin-dependent diabetes mellitus in non-obese diabetic mice by transgenes encoding modified I-A β-chain or normal I-E α-chain

  1990cited by this paper
• Prevention of diabetes in non-obese diabetic I-Ak transgenic mice

  1990cited by this paper
• Induction and therapy of autoimmune diabetes in the non-obese diabetic (NOD/Lt) mouse by a 65-kDa heat shock protein.

  1990cited by this paper
• Capacity of intact proteins to bind to MHC class II molecules.

  1989cited by this paper
• Development of autoimmune insulitis is prevented in Eαd but not in Aβk NOD transgenic mice

  1989cited by this paper
• Genetic Control of Diabetogenesis in NOD/Lt Mice: Development and Analysis of Congenic Stocks

  1989cited by this paper
• Dr3‐restricted t cells from different hla‐dr3‐positive individuals recognize the same peptide (amino acids 2–12) of the mycobacterial 65‐kda heat‐shock protein

  1989cited by this paper
• Cloning of the mycobacterial epitope recognized by T lymphocytes in adjuvant arthritis

  1988cited by this paper
• Mechanisms influencing the immunodominance of T cell determinants

  1988cited by this paper
• Prevention of autoimmune insulitis by expression of I–E molecules in NOD mice

  1987cited by this paper
• The first external domain of the nonobese diabetic mouse class II I-A beta chain is unique.

  1987cited by this paper
• The NOD mouse: recessive diabetogenic gene in the major histocompatibility complex.

  1986cited by this paper
• Antigen presentation by Ia+ B cell hybridomas to H-2-restricted T cell hybridomas.

  1982cited by this paper
• MONOCLONAL ANTIBODIES TO MOUSE MAJOR HISTOCOMPATIBILITY COMPLEX ANTIGENS: IV. A SERIES OF HYBRIDOMA CLONES PRODUCING ANTI‐H-2d ANTIBODIES AND AN EXAMINATION OF EXPRESSION OF H‐2d ANTIGENS ON THE SURFACE OF THESE CELLS

  1982cited by this paper

• The role of T-lymphocyte repertoire selection in autoimmune diseases

  2009cites this paper
• Toward Prediction of Class II Mouse Major Histocompatibility Complex Peptide Binding Affinity: in Silico Bioinformatic Evaluation Using Partial Least Squares, a Robust Multivariate Statistical Technique

  2006cites this paper
• Structure of celiac disease-associated HLA-DQ8 and non-associated HLA-DQ9 alleles in complex with two disease-specific epitopes.

  2000cites this paper