Direct modification of somatotrope function by long-term leptin treatment of primary cultured ovine pituitary cells.

No abstract is available for this paper.

• Publication year

  2001

• Venue

  Endocrinology

• Publication date

  2001-12-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1210/ENDO.142.12.8559PMID 11713211
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The in vitro effect of leptin on growth hormone secretion from primary cultured ovine somatotrophs

  2007cited by this paper
• Circulating ghrelin levels are decreased in human obesity.

  2001cited by this paper
• Localization of leptin receptor-like immunoreactivity in the corticotropes, somatotropes, and gonadotropes in the ovine anterior pituitary.

  2000cited by this paper
• The human growth hormone-releasing hormone transgenic mouse as a model of modest obesity: differential changes in leptin receptor (OBR) gene expression in the anterior pituitary and hypothalamus after fasting and OBR localization in somatotrophs.

  1999cited by this paper
• Construction and application of a multispecific competitor to quantify mRNA of matrix metalloproteinases and their tissue inhibitors in small human biopsies.

  1999cited by this paper
• Ghrelin is a growth-hormone-releasing acylated peptide from stomach

  1999cited by this paper
• Human fetal pituitary expresses functional growth hormone-releasing peptide receptors.

  1998cited by this paper
• A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction

  1998cited by this paper
• Evidence for a Leptin-Neuropeptide Y Axis for the Regulation of Growth Hormone Secretion in the Rat

  1998cited by this paper
• The in vitro Effect of Leptin onBasal and Growth Hormone-Releasing Hormone-StimulatedGrowth Hormone Secretion from theOvine Pituitary Gland

  1998cited by this paper
• Upregulation of leptin receptor gene expression in the anterior pituitary of human growth hormone-releasing hormone transgenic mice.

  1998cited by this paper
• Circadian rhythm of plasma leptin levels in upper and lower body obese women: influence of body fat distribution and weight loss.

  1998cited by this paper
• Expression and localization of the leptin receptor in endocrine and neuroendocrine tissues of the rat.

  1997cited by this paper
• Leptin receptor mRNA is expressed in ewe anterior pituitary and adipose tissues and is differentially expressed in hypothalamic regions of well-fed and feed-restricted ewes.

  1997cited by this paper
• Hyperleptinaemia: the Missing Link in the Metabolic Syndrome?

  1997cited by this paper
• Nitric oxide mediates leptin-induced luteinizing hormone-releasing hormone (LHRH) and LHRH and leptin-induced LH release from the pituitary gland.

  1997cited by this paper
• Role of leptin in hypothalamic-pituitary function.

  1997cited by this paper
• Influence of endogenous leptin tone on the estrous cycle and luteinizing hormone pulsatility in female rats.

  1997cited by this paper
• Serum leptin concentration, obesity, and insulin resistance in Western Samoans: cross sectional study

  1996cited by this paper
• A Receptor in Pituitary and Hypothalamus That Functions in Growth Hormone Release

  1996cited by this paper
• Differential impact of age, sex steroid hormones, and obesity on basal versus pulsatile growth hormone secretion in men as assessed in an ultrasensitive chemiluminescence assay.

  1995cited by this paper
• Positional cloning of the mouse obese gene and its human homologue

  1994cited by this paper
• Voltage-dependent potassium currents in ovine somatotrophs and their function in growth hormone secretion.

  1994cited by this paper
• Dual defects in pulsatile growth hormone secretion and clearance subserve the hyposomatotropism of obesity in man.

  1991cited by this paper
• Effect of restricted feeding on the concentrations of growth hormone (GH), gonadotropins, and prolactin (PRL) in plasma, and on the amounts of messenger ribonucleic acid for GH, gonadotropin subunits, and PRL in the pituitary glands of adult ovariectomized ewes.

  1990cited by this paper
• IMPAIRED GROWTH HORMONE RESPONSE TO INSULIN‐INDUCED HYPOGLYCAEMIA IN OBESE PATIENTS: RESTORATION BLOCKED BY RITANSERIN AFTER FENFLURAMINE ADMINISTRATION

  1990cited by this paper
• Enhanced growth hormone (GH) responsiveness to GH-releasing hormone after dietary manipulation in obese and nonobese subjects.

  1988cited by this paper
• Impaired growth hormone responses to growth hormone-releasing factor in obesity. A pituitary defect reversed with weight reduction.

  1984cited by this paper
• Journal of Clinical Endocrinology and Metabolism Printed in U.S.A. Copyright © 1998 by The Endocrine Society Human Fetal Pituitary Expresses Functional Growth Hormone-Releasing Peptide Receptors*

  year unknowncited by this paper
• The Journal of Clinical Endocrinology & Metabolism Printed in U.S.A. Copyright © 1999 by The Endocrine Society Leptin and Leptin Receptor Expression in Normal and Neoplastic Human Pituitary: Evidence of a Regulatory Role for Leptin on Pituitary Cell Proli

  year unknowncited by this paper
• Printed in U.S.A. Copyright © 1998 by The Endocrine Society Leptin Is a Potent Stimulator of Spontaneous Pulsatile Growth Hormone (GH) Secretion and the GH Response to GH-Releasing Hormone*

  year unknowncited by this paper

• Influence of Leptin on the Secretion of Growth Hormone in Ewes under Different Photoperiodic Conditions

  2023cites this paper
• Effects of Leptin, Growth Hormone and Photoperiod on Pituitary SOCS-3 Expression in Sheep

  2022cites this paper
• Neuroendocrine and Metabolic Regulation of Plasma Growth Hormone Secretory Profiles

  2020cites this paper
• The effects of leptin on plasma concentrations of prolactin, growth hormone, and melatonin vary depending on the stage of pregnancy in sheep.

  2018cites this paper
• Neuroendocrine Regulation of Growth Hormone Secretion.

  2016cites this paper
• Physiological Roles of Adipokines, Hepatokines, and Myokines in Ruminants

  2015cites this paper
• Adipocyte versus pituitary leptin in the regulation of pituitary hormones: somatotropes develop normally in the absence of circulating leptin.

  2014cites this paper
• Ghrelin restoration of function in vitro in somatotropes from male mice lacking the Janus kinase (JAK)-binding site of the leptin receptor.

  2013cites this paper
• Genetic polymorphisms and protein structures in growth hormone, growth hormone receptor, ghrelin, insulin-like growth factor 1 and leptin in Mehraban sheep.

  2013cites this paper
• Pituitary leptin-A paracrine regulator of gonadotropes: A review

  2011cites this paper
• The somatotrope as a metabolic sensor: deletion of leptin receptors causes obesity.

  2010cites this paper
• Resistin regulates pituitary somatotrope cell function through the activation of multiple signaling pathways.

  2009cites this paper
• Adiponectin Regulate Growth Hormone Secretion Via Adiponectin Receptor Mediated Ca2+ Signalling in Rat Somatotrophs In Vitro

  2009cites this paper
• Fasting and Glucose Effects on Pituitary Leptin Expression

  2007cites this paper
• Regulation of pituitary cell function by adiponectin.

  2007cites this paper
• Paracrinicity: The Story of 30 Years of Cellular Pituitary Crosstalk

  2007cites this paper
• La leptine : rôle physiologique dans la fonction somatotrope, transduction du signal et mécanismes d'internalisation

  2007cites this paper
• Differential regulation of GHRH-receptor and GHS-receptor expression by long-term in vitro treatment of ovine pituitary cells with GHRP-2 and GHRH

  2006cites this paper
• Development of leptin antagonists and their potential use in experimental biology and medicine.

  2006cites this paper
• Leptin and Other Endocrine Systems

  2006cites this paper
• Reduction in voltage-gated K+ currents in primary cultured rat pancreatic beta-cells by linoleic acids.

  2006cites this paper
• Growth hormone and ghrelin receptor genes are differentially expressed between genetically lean and fat selection lines of sheep.

  2006cites this paper
• Regulation and Mechanism of Growth Hormone and Insulin-like Growth Factor-I Biosynthesis and Secretion

  2005cites this paper
• Changes in Expression of the Genes for the Leptin Receptor and the Growth Hormone‐Releasing Peptide/Ghrelin Receptor in the Hypothalamic Arcuate Nucleus with Long‐Term Manipulation of Adiposity by Dietary Means

  2005cites this paper
• Physiological and Pathological Growth Hormone Secretion

  2005cites this paper
• Effect of GHRH and GHRP-2 treatment in vitro on GH secretion and levels of GH, pituitary transcription factor-1, GHRH-receptor, GH-secretagogue-receptor and somatostatin receptor mRNAs in ovine pituitary cells.

  2004influential citation
• Effects of Leptin on Intracellular Calcium Concentrations in Isolated Porcine Somatotropes

  2004cites this paper
• Leptin signaling.

  2004cites this paper
• Regulation of Leptin mRNA and Protein Expression in Pituitary Somatotropes

  2004cites this paper
• Leptin Stimulates Growth Hormone Secretion via a Direct Pituitary Effect Combined with a Decreased Somatostatin Tone in a Median Eminence-Pituitary Perifusion Study

  2004cites this paper
• The role of ghrelin and growth hormone secretagogues receptor on rat adipogenesis.

  2003cites this paper
• Effects of leptin on basal and GHRH-stimulated GH secretion from the bovine adenohypophysis are dependent upon nutritional status.

  2003cites this paper
• Association Study between Porcine LEPR-derived Microsatellite Polymorphisms and Economic Traits

  2003cites this paper
• Differential Expression of the Nonmuscle-type Cofilin Gene between Subcutaneous and Visceral Adipose Tissue

  2003cites this paper
• Characteristics of Individual Growth Curve by Porcine LEPR-derived Microsatellite Polymorphisms

  2003cites this paper
• Growth hormone releasing factor decreases long form leptin receptor expression in porcine anterior pituitary cells.

  2003cites this paper
• Interactions of Leptin, GH, and Cortisol in Normal Children

  2003cites this paper
• The Role of Phosphatidylinositol 3-kinase and Mitogenic Activated Protein Kinase on the Differentiation of Ovine Preadipocytes

  2003cites this paper
• Evaluation of the Role of Melanocortin 3 and 4 Receptors in Leptin-Stimulated and Spontaneous Growth Hormone Secretion in Rats

  2003cites this paper
• Subcloning, Expression, Purification, and Characterization of Recombinant Human Leptin-binding Domain*

  2002cites this paper
• Increase in expression of growth hormone secretagogues receptor on differentiation of ovine preadipocytes

  2002cites this paper
• Leptin Regulates Growth Hormone-Releasing Factor, Somatostatin, and α-Melanocyte-Stimulating Hormone But Not Neuropeptide Y Release in Rat Hypothalamus In Vivo: Relation with Growth Hormone Secretion

  2002cites this paper
• Growth Hormone Releasing Hormone (GHRH) and the GHRH Receptor

  2002cites this paper
• The Somatotrope as a Metabolic Sensor: Deletion of Leptin Receptors Causes Obesity Endocrinology. First Published Ahead of Print Materials and Methods Production of Deletion Mutant Mice Detection of Growth and Pubertal Changes Pituitary Cell Dispersion and Leptin Stimulation Immunolabeling Protocols

  year unknowncites this paper