RNA fusions involving CD28 are rare in peripheral T-cell lymphomas and concentrate mainly in those derived from follicular helper T cells

D. Vallois,A. Dupuy,F. Lemonnier,G. Allen,E. Missiaglia,V. Fataccioli,N. Ortonne,A. Clavert,R. Delarue,M. Rousselet,B. Fabiani,F. Llamas‐Gutierrez,S. Ogawa,M. Thome,Y. Ko,K. Kataoka,P. Gaulard,L. de Leval

Published 2018 in Haematologica

ABSTRACT

Peripheral T-cell lymphomas (PTCL) comprise usually aggressive neoplasms of mature T cells with a heterogeneous molecular background. Over the past years, several genomic studies stemming from different research groups have shown evidence that mutation-induced activation of the T-cell receptor (TCR

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