Apomorphine is a potent radical scavenger and protects cultured pheochromocytoma cells from 6-OHDA and H2O2-induced cell death.

No abstract is available for this paper.

• Publication year

  1998

• Venue

  Advances in Pharmacology

• Publication date

  Unknown publication date

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1016/S1054-3589(08)60754-1PMID 9327905
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Apomorphine is a highly potent free radical scavenger in rat brain mitochondrial fraction.

  1996cited by this paper
• Cytotoxic effects of an oxidative stress on neuronal-like pheochromocytoma cells (PC12).

  1996cited by this paper
• Apomorphine infusional therapy in parkinson's disease: Clinical utility and lack of tolerance

  1995cited by this paper
• Oxidation of free amino acids and amino acid residues in proteins by radiolysis and by metal-catalyzed reactions.

  1993cited by this paper
• PC12 pheochromocytoma cells: culture, nerve growth factor treatment, and experimental exploitation.

  1987cited by this paper

• Hormetic approaches to the treatment of Parkinson's disease: Perspectives and possibilities

  2018cites this paper
• S[+] Apomorphine is a CNS penetrating activator of the Nrf2-ARE pathway with activity in mouse and patient fibroblast models of amyotrophic lateral sclerosis☆

  2013cites this paper
• Lithium and oxidative stress lessons from the MPTP model of Parkinson's disease.

  2012cites this paper
• Dopamine D3 Receptors

  2012cites this paper
• Transcribe to Survive: Transcriptional Control of Antioxidant Defense Programs for Neuroprotection in Parkinson’s Disease

  2009cites this paper
• The putative neuroprotective role of dopamine agonists in parkinson’s disease

  2009cites this paper
• The seed extract of Cassia obtusifolia offers neuroprotection to mouse hippocampal cultures.

  2008cites this paper
• Novel multifunctional neuroprotective iron chelator‐monoamine oxidase inhibitor drugs for neurodegenerative diseases: in vitro studies on antioxidant activity, prevention of lipid peroxide formation and monoamine oxidase inhibition

  2005influential citation
• Multifunctional Activities of Green Tea Catechins in Neuroprotection

  2005cites this paper
• The Essentiality of Iron Chelation in Neuroprotection: A Potential Role of Green Tea Catechins

  2005cites this paper
• Concentration-Dependent Gene and Protein Expressions of Neuroprotective and Neurotoxic Activities of Antioxidants, Including Nutrients

  2005cites this paper
• Gene and Protein Expression Profiles of Anti‐ and Pro‐apoptotic Actions of Dopamine, R‐Apomorphine, Green Tea Polyphenol (−)‐Epigallocatechine‐3‐gallate, and Melatonin

  2003cites this paper
• Using cDNA microarray to assess Parkinson's disease models and the effects of neuroprotective drugs.

  2003cites this paper
• Involvement of Protein Kinase C Activation and Cell Survival/ Cell Cycle Genes in Green Tea Polyphenol (−)-Epigallocatechin 3-Gallate Neuroprotective Action*

  2002cites this paper
• Pramipexole attenuates the dopaminergic cell loss induced by intraventricular 6-hydroxydopamine

  2000cites this paper
• Therapeutic advances in idiopathic Parkinsonism.

  1999cites this paper
• Apomorphine protects against MPTP‐induced neurotoxicity in mice

  1999cites this paper
• Potent neuroprotective and antioxidant activity of apomorphine in MPTP and 6-hydroxydopamine induced neurotoxicity.

  1999cites this paper
• The Pivotal Role of Iron in NF‐κB Activation and Nigrostriatal Dopaminergic Neurodegeneration: Prospects for Neuroprotection in Parkinson's Disease with Iron Chelators

  1999cites this paper
• Dopamine agonists and neuroprotection in parkinson's disease

  1998cites this paper