Exposure evaluation of adult male Japanese smokers switched to a heated cigarette in a controlled clinical setting.

No abstract is available for this paper.

• Publication year

  2014

• Venue

  Regulatory toxicology and pharmacology : RTP

• Publication date

  2014-08-01

• Fields of study

  Medicine, Chemistry, Environmental Science

• Identifiers
  DOI 10.1016/j.yrtph.2014.04.016PMID 24819671
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• International Organization for Standardization

  2014cited by this paper
• Estimation of mouth level exposure to smoke constituents of cigarettes with different tar levels using filter analysis.

  2013cited by this paper
• Reduced exposure evaluation of an Electrically Heated Cigarette Smoking System. Part 3: Eight-day randomized clinical trial in the UK.

  2012cited by this paper
• Reduced exposure evaluation of an Electrically Heated Cigarette Smoking System. Part 5: 8-Day randomized clinical trial in Japan.

  2012cited by this paper
• The intractable cigarette ‘filter problem’

  2011cited by this paper
• Existing technologies to reduce specific toxicant emissions in cigarette smoke

  2008cited by this paper
• Short‐Term Clinical Exposure Evaluation of a Second‐Generation Electrically Heated Cigarette Smoking System

  2007cited by this paper
• Short‐Term Exposure Evaluation of Adult Smokers Switching From Conventional to First‐Generation Electrically Heated Cigarettes During Controlled Smoking

  2005cited by this paper
• Biomonitoring of inhaled complex mixtures--ambient air, diesel exhaust and cigarette smoke.

  2005cited by this paper
• Mainstream smoke constituent yields and predicting relationships from a worldwide market sample of cigarette brands: ISO smoking conditions.

  2004cited by this paper
• Clearing the smoke: the science base for tobacco harm reduction--executive summary.

  2001cited by this paper
• Quantitation of urinary metabolites of a tobacco-specific lung carcinogen after smoking cessation.

  1999cited by this paper
• A safer method for the measurement of plasma thiocyanate.

  1999cited by this paper
• Chemical and biological studies of a new cigarette that primarily heats tobacco. Part 3. In vitro toxicity of whole smoke.

  1998cited by this paper
• Chemical and biological studies of a new cigarette that primarily heats tobacco. Part 2. In vitro toxicology of mainstream smoke condensate.

  1998cited by this paper
• Chemical and biological studies of a new cigarette that primarily heats tobacco. Part 1. Chemical composition of mainstream smoke.

  1998cited by this paper
• Chemical and biological studies of a new cigarette that primarily heats tobacco. Part 1. Chemical composition of mainstream smoke.

  1998cited by this paper
• Chemical and biological studies of a newCigarette that primarily heats tobacco. Part 2. In vitro toxicology of mainstreamsmoke condensate

  1998cited by this paper
• Human urine mutagenicity study comparing cigarettes which burn or primarily heat tobacco.

  1996cited by this paper
• Comparative studies on the genotoxic activity of mainstream smoke condensate from cigarettes which burn or only heat tobacco

  1990cited by this paper
• Human urine mutagenicity study comparing cigarettes which burn or only heat tobacco.

  1989cited by this paper
• Ninety-Day Inhalation Study in Rats, Comparing Smoke from Cigarettes That Heat Tobacco with Those That Burn Tobacco1

  1989cited by this paper
• The kinetics of mutagen excretion in the urine of cigarette smokers.

  1985cited by this paper
• Changes in serum thiocyanate concentration on stopping smoking.

  1985cited by this paper
• A simple modification of the Salmonella liquid-incubation assay. Increased sensitivity for detecting mutagens in human urine.

  1983cited by this paper
• Concentration of mutagens from urine by absorption with the nonpolar resin XAD-2: cigarette smokers have mutagenic urine.

  1977cited by this paper
• Smoking and health.

  1970cited by this paper

• Heated Tobacco Products: Emerging Health Outcomes and Insights into Oxidative Stress and Pro-Inflammatory-Driving Mechanisms

  2025cites this paper
• Assessing the comparability of toxic emissions reduction from heated tobacco aerosols relative to cigarette smoke: a scientific approach to bridging datasets

  2025cites this paper
• Assessing biomarkers of exposure to carcinogens associated with combustible cigarettes, electronic cigarettes, and heated tobacco products: a systematic review and meta-analysis

  2025cites this paper
• The chemical memory of smoking tobacco.

  2024cites this paper
• Biomarkers of Exposure to Nicotine and Selected Toxicants in Individuals Who Use Alternative Tobacco Products Sold in Japan and Canada from 2018 to 2019

  2024cites this paper
• SYSTEMATIC REVIEW OF THE RELATIONSHIP BETWEEN TOBACCO SMOKE AND CARBON MONOXIDE: IMPACT ON HEALTH AND DISEASE

  2023cites this paper
• Biomarkers of exposure in urine of active smokers, non-smokers, and vapers

  2023cites this paper
• Oxidative stress‐mediated epidermal growth factor receptor activation by cigarette smoke or heated tobacco aerosol in human primary bronchial epithelial cells from multiple donors

  2023cites this paper
• A Systematic Review and Meta-Analysis on Human Biomarkers of Exposure from Heated Tobacco Products Compared to Conventional Cigarettes among Adult Smokers

  2022cites this paper
• Multiple endpoint in vitro toxicity assessment of a prototype heated tobacco product indicates substantially reduced effects compared to those of combustible cigarette.

  2022cites this paper
• Compounds in cigarette smoke induce EGR1 expression via the AHR, resulting in apoptosis and COPD.

  2022cites this paper
• Use of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes to Predict the Cardiotoxicity Potential of Next Generation Nicotine Products

  2022influential citation
• Clinical Assessment of ENDPs

  2021cites this paper
• Systematic review of biomarker findings from clinical studies of electronic cigarettes and heated tobacco products

  2021cites this paper
• Resolution and quantitation of mercapturic acids derived from crotonaldehyde, methacrolein, and methyl vinyl ketone in the urine of smokers and non-smokers.

  2020influential citation
• Human Biomarker Exposure from Cigarettes versus Novel Heat-Not-Burn Devices: A Systematic Review and Meta-Analysis.

  2020cites this paper
• A review of the analysis of biomarkers of exposure to tobacco and vaping products.

  2020cites this paper
• Harms and benefits of e-cigarettes and heat-not-burn tobacco products: a literature map.

  2020cites this paper
• Cigarette smoke, but not novel tobacco vapor products, causes epigenetic disruption and cell apoptosis

  2020cites this paper
• [Systematic analysis of the scientific literature on heated tobacco].

  2019cites this paper
• A combined analytical method for biological monitoring of arsenic, benzene and polycyclic aromatic hydrocarbons in human urine by liquid chromatography tandem mass spectrometry.

  2019cites this paper
• Le tabac chauffé : revue systématique de la littérature

  2019cites this paper
• Favorable Changes in Biomarkers of Potential Harm to Reduce the Adverse Health Effects of Smoking in Smokers Switching to the Menthol Tobacco Heating System 2.2 for 3 Months (Part 2)

  2019cites this paper
• Chemical analysis and in vitro toxicological evaluation of aerosol from a novel tobacco vapor product: A comparison with cigarette smoke

  2018cites this paper
• Assessment of the exposure to harmful and potentially harmful constituents in healthy Japanese smokers using a novel tobacco vapor product compared with conventional cigarettes and smoking abstinence

  2018cites this paper
• Oxidative stress responses in human bronchial epithelial cells exposed to cigarette smoke and vapor from tobacco‐ and nicotine‐containing products

  2018cites this paper
• Carbon monoxide levels after inhalation from new generation heated tobacco products

  2018cites this paper
• Effects of Switching to the Tobacco Heating System 2.2 Menthol, Smoking Abstinence, or Continued Cigarette Smoking on Biomarkers of Exposure: A Randomized, Controlled, Open-Label, Multicenter Study in Sequential Confinement and Ambulatory Settings (Part 1)

  2017cites this paper
• Tobacco papers and tobacco industry ties in regulatory toxicology and pharmacology

  2017cites this paper
• Pharmacokinetics of nicotine following the controlled use of a prototype novel tobacco vapor product

  2017cites this paper
• Effects of Switching to the Menthol Tobacco Heating System 2.2, Smoking Abstinence, or Continued Cigarette Smoking on Clinically Relevant Risk Markers: A Randomized, Controlled, Open-Label, Multicenter Study in Sequential Confinement and Ambulatory Settings (Part 2)

  2017cites this paper
• A randomised, controlled, two-Centre open-label study in healthy Japanese subjects to evaluate the effect on biomarkers of exposure of switching from a conventional cigarette to a tobacco heating product

  2017cites this paper
• ssessing the mutagenic activities of smoke from different cigarettes n direct exposure experiments using the modified Ames Salmonella ssay

  2016cites this paper
• Evaluation of the Tobacco Heating System 2.2. Part 8: 5-Day randomized reduced exposure clinical study in Poland.

  2016cites this paper
• Evaluation of the tobacco heating system 2.2. Part 9: Application of systems pharmacology to identify exposure response markers in peripheral blood of smokers switching to THS2.2.

  2016cites this paper
• Acrolein inhalation alters arterial blood gases and triggers carotid body-mediated cardiovascular responses in hypertensive rats

  2015influential citation
• A study to investigate changes in the levels of biomarkers of exposure to selected cigarette smoke constituents in Japanese adult male smokers who switched to a non-combustion inhaler type of tobacco product.

  2015cites this paper
• Biological responses in rats exposed to mainstream smoke from a heated cigarette compared to a conventional reference cigarette

  2015cites this paper