Mycoplasma Superantigen Is a CDR 3-dependent Ligand for the T Cell Antigen Receptor

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  1998

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• A human endogenous retroviral superantigen as candidate autoimmune gene in type I diabetes.

  1997cited by this paper
• Ligand-specific oligomerization of T-cell receptor molecules

  1997cited by this paper
• Crystal structure of a T-cell receptor β-chain complexed with a superantigen

  1996cited by this paper
• An αβ T Cell Receptor Structure at 2.5 Å and Its Orientation in the TCR-MHC Complex

  1996influential reference
• TCR recognition of the Hb(64-76)/I-Ek determinant: single conservative amino acid changes in the complementarity-determining region 3 dramatically alter antigen fine specificity.

  1996cited by this paper
• The sequence of the Mycoplasma arthritidis superantigen, MAM: identification of functional domains and comparison with microbial superantigens and plant lectin mitogens

  1996cited by this paper
• Allelic variants of human TCR BV17S1 defined by restriction fragment length polymorphism, single strand conformation polymorphism, and amplification refractory mutation system analyses.

  1996cited by this paper
• Spread of clonal T-cell expansions in rheumatoid arthritis patients.

  1996cited by this paper
• Organ-specific disease provoked by systemic autoimmunity.

  1996cited by this paper
• The J beta segment of the T cell receptor contributes to the V beta-specific T cell expansion caused by staphylococcal enterotoxin B and Urtica dioica superantigens.

  1996cited by this paper
• TCR binding differs for a bacterial superantigen (SEE) and a viral superantigen (Mtv-9)

  1996cited by this paper
• Structure of the complex between human T-cell receptor, viral peptide and HLA-A2

  1996influential reference
• Different superantigens interact with distinct sites in the Vbeta domain of a single T cell receptor

  1996cited by this paper
• T-cell-receptor affinity and thymocyte positive selection

  1996cited by this paper
• Selective binding of self peptides to disease-associated major histocompatibility complex (MHC) molecules: a mechanism for MHC-linked susceptibility to human autoimmune diseases

  1995cited by this paper
• Increased peptide promiscuity provides a rationale for the lack of N regions in the neonatal T cell repertoire.

  1995cited by this paper
• Correlation between disease phenotype and genetic heterogeneity in rheumatoid arthritis.

  1995cited by this paper
• BETA CHAIN OF A T CELL ANTIGEN RECEPTOR

  1995cited by this paper
• Persistence of V beta 6+ T cells in Mls-1a mice. A role for the third complementarity-determining region (CDR3) of the T cell receptor beta chain in superantigen recognition.

  1995influential reference
• Selective expansion followed by profound deletion of mature V beta 8.3+ T cells in vivo after exposure to the superantigenic lectin Urtica dioica agglutinin.

  1995cited by this paper
• Efficient immune responses in mice lacking N‐region diversity

  1995cited by this paper
• Superantigens of mouse mammary tumor virus.

  1995cited by this paper
• Subsets of HLA-DR1 molecules defined by SEB and TSST-1 binding.

  1994cited by this paper
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  1994cited by this paper
• The Mycoplasma arthritidis superantigen MAM: purification and identification of an active peptide

  1994cited by this paper
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  1994cited by this paper
• CDR3 sequence motifs shared by oligoclonal rheumatoid arthritis synovial T cells. Evidence for an antigen-driven response.

  1994influential reference
• Human T-cell responses to Mycoplasma arthritidis-derived superantigen

  1994cited by this paper
• Major histocompatibility complex-specific recognition of Mls-1 is mediated by multiple elements of the T cell receptor

  1993cited by this paper
• Mice lacking TdT: mature animals with an immature lymphocyte repertoire.

  1993cited by this paper
• Superantigen-induced immune stimulation amplifies mouse mammary tumor virus infection and allows virus transmission.

  1993cited by this paper
• Production of high-titer helper-free retroviruses by transient transfection.

  1993cited by this paper
• Lack of N regions in antigen receptor variable region genes of TdT-deficient lymphocytes.

  1993cited by this paper
• How do T-cell receptors, MHC molecules and superantigens get together?

  1993cited by this paper
• Skewed T cell receptor V alpha repertoire among superantigen reactive murine T cells.

  1993cited by this paper
• V(D)J recombination: molecular biology and regulation.

  1992cited by this paper
• Mapping T-cell receptor–peptide contacts by variant peptide immunization of single-chain transgenics

  1992cited by this paper
• An experimentally validated panel of subfamily‐specific oligonucleotide primers (Vα1‐w29/Vβ1‐w24) for the study of human T cell receptor variable V gene segment usage by polymerase chain reaction

  1992cited by this paper
• Evidence for a viral superantigen in humans

  1992cited by this paper
• Influence of T cell receptor V alpha expression on Mlsa superantigen- specific T cell responses

  1992cited by this paper
• Transgenic mouse mammary tumor virus superantigen expression prevents viral infection.

  1992cited by this paper
• Human B cell differentiation induced by microbial superantigens: unselected peripheral blood lymphocytes secrete polyclonal immunoglobulin in response to Mycoplasma arthritidis mitogen.

  1992cited by this paper
• A superantigen encoded in the open reading frame of the 3′ long terminal repeat of mouse mammary tumour virus

  1991cited by this paper
• MHC class-II molecules and autoimmunity.

  1991cited by this paper
• The Mycoplasma arthritidis T-cell mitogen, MAM: a model superantigen.

  1991influential reference
• Limited T-cell receptor beta-chain heterogeneity among interleukin 2 receptor-positive synovial T cells suggests a role for superantigen in rheumatoid arthritis.

  1991cited by this paper
• The V beta 17+ T cell repertoire: skewed J beta usage after thymic selection; dissimilar CDR3s in CD4+ versus CD8+ cells

  1991cited by this paper
• A special repertoire of alpha:beta T cells in neonatal mice.

  1991cited by this paper
• Characterization of human T cells reactive with the Mycoplasma arthritidis-derived superantigen (MAM): generation of a monoclonal antibody against V beta 17, the T cell receptor gene product expressed by a large fraction of MAM-reactive human T cells

  1991cited by this paper
• HLA-DR alleles differ in their ability to present staphylococcal enterotoxins to T cells

  1990cited by this paper
• Residues of the variable region of the T-cell-receptor β-chain that interact with S. aureus toxin superantigens

  1990cited by this paper
• Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line.

  1990cited by this paper
• The staphylococcal enterotoxins and their relatives.

  1990cited by this paper
• Identification of the region of T cell receptor β chain that interacts with the self-superantigen MIs-1a

  1990cited by this paper
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  1990cited by this paper
• T‐Cell Responses to Mls and to Bacterial Proteins that Mimic its Behavior #

  1989cited by this paper
• Site-directed mutagenesis by overlap extension using the polymerase chain reaction.

  1989influential reference
• Characterization of a monoclonal antibody which detects all murine alpha beta T cell receptors.

  1989cited by this paper
• The outline structure of the T‐cell alpha beta receptor.

  1988cited by this paper
• Site-directed mutations in the VDJ junctional region of a T cell receptor beta chain cause changes in antigenic peptide recognition.

  1988cited by this paper
• Clonal analysis of human T cell activation by the Mycoplasma arthritidis mitogen (MAS)

  1988cited by this paper
• The shared epitope hypothesis. An approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis.

  1987cited by this paper
• A third rearranged and expressed gene in a clone of cytotoxic T lymphocytes

  1984cited by this paper
• Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays.

  1983cited by this paper

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  2006cites this paper
• Cell adhesion molecules in the pathogenesis of and host defence against microbial infection.

  1999cites this paper