Severe leukopenia in a rheumatoid arthritis patient treated with a methotrexate/leflunomide combination.

P. Toth,R. Bernd

Published 2014 in Revista Brasileira de Reumatologia

ABSTRACT

A rheumatoid arthritis patient was treated for two years with methotrexate and leflunomide combination therapy. The evolution was uneventful until she had clopidogrel, simvastatin, isosorbide, aspirin and omeprazole added to medication due to acute myocardial infarction. Four weeks after this, she was hospitalized with severe leukopenia.

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