Triplet Repeat Instability and DNA Topology: An Expansion Model Based on Statistical Mechanics*

No abstract is available for this paper.

• Publication year

  1997

• Venue

  Journal of Biological Chemistry

• Publication date

  1997-07-04

• Fields of study

  Biology, Medicine, Physics

• Identifiers
  DOI 10.1074/jbc.272.27.16793PMID 9201984
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Flexible DNA: Genetically Unstable CTG·CAG and CGG·CCG from Human Hereditary Neuromuscular Disease Genes*

  1997cited by this paper
• Hairpin Formation during DNA Synthesis Primer Realignmentin Vitro in Triplet Repeat Sequences from Human Hereditary Disease Genes*

  1997cited by this paper
• Alternative structures in duplex DNA formed within the trinucleotide repeats of the myotonic dystrophy and fragile X loci.

  1996cited by this paper
• Cloning, characterization and properties of plasmids containing CGG triplet repeats from the FMR-1 gene.

  1996cited by this paper
• Trinucleotide repeats in neurogenetic disorders.

  1996cited by this paper
• Friedreich's Ataxia: Autosomal Recessive Disease Caused by an Intronic GAA Triplet Repeat Expansion

  1996cited by this paper
• DNA topoisomerases.

  1996cited by this paper
• Triplet repeat expansion mutations: the example of fragile X syndrome.

  1995cited by this paper
• Pausing of DNA Synthesis in Vitro at Specific Loci in CTG and CGG Triplet Repeats from Human Hereditary Disease Genes (*)

  1995cited by this paper
• Trinucleotide repeat expansion and human disease.

  1995cited by this paper
• Expansion and deletion of CTG repeats from human disease genes are determined by the direction of replication in E. coli

  1995cited by this paper
• Determination of DNA persistence length by cryo-electron microscopy. Separation of the static and dynamic contributions to the apparent persistence length of DNA.

  1995cited by this paper
• Investigation of the Influence of Cytosine Methylation on DNA Flexibility (*)

  1995cited by this paper
• Error-prone replication of repeated DNA sequences by T7 DNA polymerase in the absence of its processivity subunit.

  1994cited by this paper
• Detection of localized DNA flexibility

  1994cited by this paper
• DNA methylation represses FMR-1 transcription in fragile X syndrome.

  1992cited by this paper
• Direct evidence for the effect of transcription on local DNA supercoiling in vivo.

  1992cited by this paper
• Absence of expression of the FMR-1 gene in fragile X syndrome.

  1991cited by this paper
• Application of the method of phage T4 DNA ligase-catalyzed ring-closure to the study of DNA structure. II. NaCl-dependence of DNA flexibility and helical repeat.

  1990cited by this paper
• Application of the method of phage T4 DNA ligase-catalyzed ring-closure to the study of DNA structure. I. Computational analysis.

  1990cited by this paper
• DNA topology and its biological effects

  1990influential reference
• Flexibility of DNA.

  1988cited by this paper
• Supercoiling of the DNA template during transcription.

  1987cited by this paper
• Ring closure probabilities for DNA fragments by Monte Carlo simulation.

  1986cited by this paper
• Topological distributions and the torsional rigidity of DNA. A Monte Carlo study of DNA circles.

  1986cited by this paper
• Analysis of the ring‐closure probabilities of isotropic wormlike chains: Application to duplex DNA

  1985cited by this paper
• Statistical mechanics of DNA topoisomers. The helical worm-like chain.

  1985cited by this paper
• Ring-closure probabilities for twisted wormlike chains: application to DNA

  1984cited by this paper
• Torsional rigidity of DNA and length dependence of the free energy of DNA supercoiling.

  1984cited by this paper
• Energetics of DNA twisting. I. Relation between twist and cyclization probability.

  1983cited by this paper
• Energetics of DNA twisting. II. Topoisomer analysis.

  1983cited by this paper
• Orientation relaxation of DNA restriction fragments and the internal mobility of the double helix.

  1982cited by this paper
• Monte carlo computation of the supercoiling energy, the sedimentation constant, and the radius of gyration of unknotted and knotted circular DNA

  1980cited by this paper
• Action of nicking-closing enzyme on supercoiled and nonsupercoiled closed circular DNA: formation of a Boltzmann distribution of topological isomers.

  1975cited by this paper
• Conformational fluctuations of DNA helix.

  1975cited by this paper
• Effect of incubation conditions on the nucleotide sequence of DNA products of unprimed DNA polymerase reactions.

  1970cited by this paper

• Unique sequence-dependent properties of trinucleotide repeat monolayers: electrochemical, electrical, and topographic characterization.

  2020cites this paper
• Effects of DNA supercoiling on chromatin architecture

  2016cites this paper
• Effects of DNA supercoiling on chromatin architecture

  2016cites this paper
• Modelling and inference reveal nonlinear length-dependent suppression of somatic instability for small disease associated alleles in myotonic dystrophy type 1 and Huntington disease

  2013cites this paper
• Role of the closing base pair for d(GCA) hairpin stability: free energy analysis and folding simulations

  2011cites this paper
• PHOTO-INDUCED CHARGE FLOW THROUGH CANONICAL DNA/RNA AND NON-CANONICAL DNA CONTAINING TRINUCLEOTIDE REPEATS

  2010cites this paper
• The common fragile site genes CNTLN and LINGO2 are associated with increased genomic instability in different tumors

  2010cites this paper
• Transcription destabilizes triplet repeats

  2009cites this paper
• Sequence determinants of human microsatellite variability

  2009cites this paper
• Human chromosome fragility.

  2008influential citation
• Genome-wide analysis of microsatellite polymorphism in chicken circumventing the ascertainment bias.

  2008cites this paper
• NMR proton chemical shift prediction of T·T mismatches in B-DNA duplexes.

  2007cites this paper
• Folding of a DNA hairpin loop structure in explicit solvent using replica-exchange molecular dynamics simulations.

  2007cites this paper
• Proton chemical shift prediction of A.A mismatches in B-DNA duplexes.

  2007cites this paper
• Fragile X repeats are potent inducers of complex, multiple site rearrangements in flanking sequences in Escherichia coli.

  2007cites this paper
• Structural and dynamic basis of a supercoiling-responsive DNA element

  2006cites this paper
• The molecular basis of common and rare fragile sites.

  2006cites this paper
• Misregulation of alternative splicing causes pathogenesis in myotonic dystrophy.

  2006cites this paper
• Increased Negative Superhelical Density in Vivo Enhances the Genetic Instability of Triplet Repeat Sequences*

  2005cites this paper
• The influence of sequence context and length on the kinetics of DNA duplex formation from complementary hairpins possessing (CNG) repeats.

  2005cites this paper
• Structural roles of CTG repeats in slippage expansion during DNA replication

  2005cites this paper
• Structural roles of CTG repeats in slippage expansion during DNA replication

  2005cites this paper
• Structural roles of CTG repeats in slippage expansion during DNA replication

  2005cites this paper
• Influence of sequence context and length on the structure and stability of triplet repeat DNA oligomers.

  2004cites this paper
• Brohede, J. 2003. Rates and Patterns of Mutation in Microsatellite DNA. Acta Universitatis Upsaliensis. Comprehensive Summaries of Uppsala Dissertations from the Faculty of Science and Technology 803. 51 pp. Uppsala. ISBN 91-554-5524-7

  2003cites this paper
• Trinucleotide repeat instability: a hairpin curve at the crossroads of replication, recombination, and repair

  2003cites this paper
• Molecular Basis for Expression of Common and Rare Fragile Sites

  2003cites this paper
• Long CTG·CAG Repeats from Myotonic Dystrophy Are Preferred Sites for Intermolecular Recombination*

  2002cites this paper
• Molecular mechanisms of TRS instability.

  2002cites this paper
• Roles of recombination in trinucleotide repeat instability in E.coli

  2002cites this paper
• Developmental Timing and the Role of Cis and Trans Acting Modifiers on CTG Repeat Instability in Murine Models

  2001cites this paper
• Structural features of trinucleotide repeats associated with DNA expansion.

  2001cites this paper
• Recombinant Human DNA (Cytosine-5) Methyltransferase

  2001cites this paper
• DNA interstrand crosslink formation by mechlorethamine at a cytosine-cytosine mismatch pair: kinetics and sequence dependence.

  2001cites this paper
• Base Stacking and Even/Odd Behavior of Hairpin Loops in DNA Triplet Repeat Slippage and Expansion with DNA Polymerase*

  2000cites this paper
• Myotonic Muscular Dystrophy Genetics and Cardiac Sequelae

  2000cites this paper
• Tandem Duplication

  2000cites this paper
• Nucleotide excision repair affects the stability of long transcribed (CTG*CAG) tracts in an orientation-dependent manner in Escherichia coli.

  1999cites this paper
• Expansion and Deletion of Triplet Repeat Sequences inEscherichia coli Occur on the Leading Strand of DNA Replication*

  1999cites this paper
• Genetic Instabilities in (CTG·CAG) Repeats Occur by Recombination*

  1999cites this paper
• Analysis of Strand Slippage in DNA Polymerase Expansions of CAG/CTG Triplet Repeats Associated with Neurodegenerative Disease*

  1998cites this paper
• Small Slipped Register Genetic Instabilities in Escherichia coli in Triplet Repeat Sequences Associated with Hereditary Neurological Diseases*

  1998cites this paper
• Molecular Evolution: Towards the Origin of Metazoa

  1998cites this paper
• DMPK and myotonic dystrophy : effects of CTG trinucleotide expansion upon DMPK and their contribution to DM pathogenesis

  1998cites this paper
• The Influence of a Human Repetitive Dna on Genome Stability

  1998cites this paper
• Instabilities of triplet repeats: factors and mechanisms.

  1998cites this paper
• Hairpin Formation during DNA Synthesis Primer Realignmentin Vitro in Triplet Repeat Sequences from Human Hereditary Disease Genes*

  1997cites this paper
• Flexible DNA: Genetically Unstable CTG·CAG and CGG·CCG from Human Hereditary Neuromuscular Disease Genes*

  1997cites this paper
• List of Thesis Papers Papers I-iv Are Available in Appendix 1 Individual Variation in Microsatellite Mutation Rate in Barn Swallows. (manuscript) Summaries of Papers including Discussion.. 26

  year unknowncites this paper