Ethnomedicine, Phytochemistry and Pharmacology of Smilax glabra: An Important Traditional Chinese Medicine.

No abstract is available for this paper.

• Publication year

  2018

• Venue

  The American Journal of Chinese Medicine

• Publication date

  2018-03-15

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1142/S0192415X18500143PMID 29433390
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Ferulic acid promoting apoptosis in human osteosarcoma cell lines

  2017cited by this paper
• Anticancer Properties and Pharmaceutical Applications of Plumbagin: A Review.

  2017cited by this paper
• Pyranocoumarin Tissue Distribution, Plasma Metabolome and Prostate Transcriptome Impacts of Sub-Chronic Exposure to Korean Angelica Supplement in Mice.

  2016cited by this paper
• Astilbin inhibits Th17 cell differentiation and ameliorates imiquimod-induced psoriasis-like skin lesions in BALB/c mice via Jak3/Stat3 signaling pathway.

  2016influential reference
• Epigallocatechin-3-gallate Prevents Triptolide-Induced Hepatic Injury by Restoring the Th17/Treg Balance in Mice.

  2016cited by this paper
• Effects of 5,6-Dihydroxy-2,4-Dimethoxy-9,10-Dihydrophenanthrene on G2/M Cell Cycle Arrest and Apoptosis in Human Lung Carcinoma Cells.

  2016cited by this paper
• The Anti-Oxidant and Antitumor Properties of Plant Polysaccharides.

  2016cited by this paper
• Effects of American Ginseng on Preimplantation Development and Pregnancy in Mice.

  2016cited by this paper
• Punicalagin Prevents Hypoxic Pulmonary Hypertension via Anti-Oxidant Effects in Rats.

  2016cited by this paper
• Baicalein Reduces Liver Injury Induced by Myocardial Ischemia and Reperfusion.

  2016cited by this paper
• Smilax glabra Roxb targets Aktp-Thr308 and inhibits Akt-mediated signaling pathways in SGC7901 cells

  2016influential reference
• Polysaccharides from Smilax glabra inhibit the pro-inflammatory mediators via ERK1/2 and JNK pathways in LPS-induced RAW264.7 cells.

  2015influential reference
• Sarsaparilla (Smilax Glabra Rhizome) Extract Inhibits Cancer Cell Growth by S Phase Arrest, Apoptosis, and Autophagy via Redox-Dependent ERK1/2 Pathway

  2015influential reference
• Inhibitory Effects of Chemical Compounds Isolated from the Rhizome of Smilax glabra on Nitric Oxide and Tumor Necrosis Factor-α Production in Lipopolysaccharide-Induced RAW264.7 Cell

  2015influential reference
• Sarsaparilla (Smilax Glabra Rhizome) Extract Inhibits Migration and Invasion of Cancer Cells by Suppressing TGF-β1 Pathway

  2015influential reference
• Optimization of Astilbin Extraction from the Rhizome of Smilax glabra, and Evaluation of Its Anti-Inflammatory Effect and Probable Underlying Mechanism in Lipopolysaccharide-Induced RAW264.7 Macrophages

  2015cited by this paper
• Anti-Allergic Activities of Smilax glabra Rhizome Extracts and Its Isolated Compounds.

  2015cited by this paper
• Medicinal effect and its JP2/RyR2-based mechanism of Smilax glabra flavonoids on angiotensin II-induced hypertrophy model of cardiomyocytes.

  2015cited by this paper
• Evaluation of Acute Toxicity Effect of Smilax Glabra Extract on White Albino Rats

  2015influential reference
• Antioxidant and Anti-Inflammatory Activities of Phenolic-Enriched Extracts of Smilax glabra

  2014influential reference
• The protective effect of Smilax glabra extract on advanced glycation end products-induced endothelial dysfunction in HUVECs via RAGE-ERK1/2-NF-κB pathway.

  2014cited by this paper
• Effect of Compound Rhizoma Smilacis Glabrae Granules on Inflammatory Factors and mi-RNA in Synovial Cells of Rats

  2014cited by this paper
• Modulation effect of Smilax glabra flavonoids on ryanodine receptor mediated intracellular Ca2+ release in cardiomyoblast cells.

  2013cited by this paper
• Chemical Constituents from the Rhizomes of Smilax glabra and Their Antimicrobial Activity

  2013influential reference
• Chemistry and Biological Activities of Flavonoids: An Overview

  2013cited by this paper
• Protective Effects of the Flavonoid-Rich Fraction from Rhizomes of Smilax glabra Roxb. on Carbon Tetrachloride-Induced Hepatotoxicity in Rats

  2013influential reference
• Modulation of apoptosis in human hepatocellular carcinoma (HepG2 cells) by a standardized herbal decoction of Nigella sativa seeds, Hemidesmus indicus roots and Smilax glabra rhizomes with anti- hepatocarcinogenic effects

  2012cited by this paper
• Mitochondrial apoptosis contributes to the anti-cancer effect of Smilax glabra Roxb.

  2011influential reference
• Protective effect of Smilax glabra extract against lead-induced oxidative stress in rats.

  2010influential reference
• A comparison of the cytotoxic potential of standardized aqueous and ethanolic extracts of a polyherbal mixture comprised of Nigella sativa (seeds), Hemidesmus indicus (roots) and Smilax glabra (rhizome)

  2010cited by this paper
• Hepatoprotective effect of syringic acid and vanillic acid on CCl4-induced liver injury.

  2010cited by this paper
• Antioxidant activity of Rhizoma Smilacis Glabrae extracts and its key constituent-astilbin

  2009influential reference
• Hepatoprotective effect of syringic acid and vanillic acid on concanavalin a-induced liver injury.

  2009cited by this paper
• Effect of Astilbin on Experimental Diabetic Nephropathy in vivo and in vitro

  2009cited by this paper
• Astilbin inhibits the adhesion of T lymphocytes via decreasing TNF-alpha and its associated MMP-9 activity and CD44 expression.

  2008influential reference
• Determination of yam in Rhizoma smilacis glabrae. by HPLC

  2008influential reference
• Anti-proliferative and pro-apoptotic effect of Smilax glabra Roxb. extract on hepatoma cell lines.

  2008influential reference
• Antiviral and anti-proliferative glycoproteins from the rhizome of Smilax glabra Roxb (Liliaceae).

  2008influential reference
• Herbal formulation, Yukmi-jihang-tang-Jahage, regulates bone resorption by inhibition of phosphorylation mediated by tyrosine kinase Src and cyclooxygenase expression.

  2006cited by this paper
• A long-term investigation of the anti-hepatocarcinogenic potential of an indigenous medicine comprised of Nigella sativa, Hemidesmus indicus and Smilax glabra

  2006cited by this paper
• Anti-HIV-1 protease- and HIV-1 integrase activities of Thai medicinal plants known as Hua-Khao-Yen.

  2006influential reference
• Smilaxin, a novel protein with immunostimulatory, antiproliferative, and HIV-1-reverse transcriptase inhibitory activities from fresh Smilax glabra rhizomes.

  2006influential reference
• Determination of Chemical Constituents of the Essential Oil from Smilax glabra Roxb.

  2006cited by this paper
• Cardiovascular protective effects of resveratrol.

  2006cited by this paper
• Astilbin inhibits contact hypersensitivity through negative cytokine regulation distinct from cyclosporin A.

  2005influential reference
• Cytotoxic effects of a decoction of Nigella sativa, Hemidesmus indicus and Smilax glabra on human hepatoma HepG2 cells.

  2005influential reference
• New mannose-binding lectin isolated from the rhizome of Sarsaparilla Smilax glabra Roxb. (Liliaceae).

  2004cited by this paper
• In vitro cytotoxic activity of Thai medicinal plants used traditionally to treat cancer.

  2004cited by this paper
• Isolation,identification of the chemical constituents from Smilax glabra Roxb.

  2004cited by this paper
• Phenolic glycosides from rhizome of Smilax glabra

  2004cited by this paper
• Astilbin prevents concanavalin A‐induced liver injury by reducing TNF‐α production and T lymphocyte adhesion

  2004cited by this paper
• [Studies on dihydroflavonol glycosides from rhizome of Smilax glabra].

  2004cited by this paper
• Astilbin prevents concanavalin A-induced liver injury by reducing TNF-alpha production and T lymphocytes adhesion.

  2004cited by this paper
• Protection against diethylnitrosoamine-induced hepatocarcinogenesis by an indigenous medicine comprised of Nigella sativa, Hemidesmus indicus and Smilax glabra: a preliminary study

  2003influential reference
• Immunomodulatory activity of the aqueous extract from rhizome of Smilax glabra in the later phase of adjuvant-induced arthritis in rats.

  2003cited by this paper
• Astilbin suppresses collagen-induced arthritis via the dysfunction of lymphocytes

  2003cited by this paper
• Phenolic composition of champagnes from Chardonnay and Pinot Noir vintages.

  2003cited by this paper
• Determination of the contents of inorganic element in Smilax Glabra

  2003cited by this paper
• Flavonoid antioxidants: chemistry, metabolism and structure-activity relationships.

  2002cited by this paper
• Inhibitory effect of a Korean traditional medicine, Honghwain-Jahage (water extracts of Carthamus tinctorius L. seed and Hominis placenta) on interleukin-1-mediated bone resorption.

  2002cited by this paper
• Biological activity of astilbin from Dimorphandra mollis against Anticarsia gemmatalis and Spodoptera frugiperda.

  2002cited by this paper
• Astilbin selectively facilitates the apoptosis of interleukin-2-dependent phytohemagglutinin-activated Jurkat cells.

  2001cited by this paper
• Isolation of a novel heterodimeric agglutinin from rhizomes of Smilax glabra, the Chinese medicinal material tufuling.

  2001cited by this paper
• Phenylpropanoid glycosides from Smilax glabra.

  2000cited by this paper
• Syphilis: Review with Emphasis on Clinical, Epidemiologic, and Some Biologic Features

  1999cited by this paper
• Rehmannia glutinosa inhibits tumour necrosis factor-alpha and interleukin-1 secretion from mouse astrocytes.

  1999cited by this paper
• A new flavanone isolated from rhizoma smilacis glabrae and the structural requirements of its derivatives for preventing immunological hepatocyte damage.

  1999cited by this paper
• Astilbin selectively induces dysfunction of liver-infiltrating cells--novel protection from liver damage.

  1999cited by this paper
• [Studies on the chemical constituents of Smilax glabra].

  1998cited by this paper
• The Chemistry and Biological Effects of Flavonoids and Phenolic Acids a

  1998cited by this paper
• A New Isoflavone from Smilax glabra

  1998cited by this paper
• Hypoglycemic effect of the rhizomes of Smilax glabra in normal and diabetic mice.

  1997cited by this paper
• Anti-inflammatory activity of the aqueous extract from Rhizoma smilacis glabrae.

  1997influential reference
• [Flavanonol glucosides of Smilax glabra Roxb].

  1996cited by this paper
• Structure-antioxidant activity relationships of flavonoids and phenolic acids.

  1996cited by this paper
• CHEMICAL STUDIES OF SMILAX GLABRA (III). ISOLATION AND IDENTIFICATION OF SMIGLANIN FROM SMILAX GLABLA

  1995cited by this paper
• A NEW CHROME GLYCOSIDE FROM SMILAX GLABRA ROXB

  1995cited by this paper

• The genus Smilax L.: A comprehensive review of traditional uses, phytochemistry, pharmacological activities, and toxicity

  2026cites this paper
• Flavonoid biosynthesis in Smilax glabra Roxb: Insights from integrated transcriptomic and metabolomic approach

  2026cites this paper
• Protective Role and Mechanism of Flavonoids from Smilax glabra Roxb. against Lead-Induced Neurotoxicity and Hematotoxicity in Danio rerio.

  2026cites this paper
• Smilax glabra roxb. alleviates cisplatin-induced acute kidney injury in mice by activating the Nrf2/HO-1 Signalling Pathway.

  2025cites this paper
• Bibliometric analysis of global research trends and development prospects of Smilax glabra Roxb using CiteSpace

  2025cites this paper
• Colloidal self-assembly of astilbin with smilax glabra polysaccharides enables carrier-free delivery and improved anti-inflammatory performance.

  2025cites this paper
• Identification of chemical constituents of Smilax glabra Roxb. and comparative study on pharmacokinetics of 12 main bioactive components in normal and hyperuricemia rats by UPLC-Q-Exactive Orbitrap-HRMS method.

  2025cites this paper
• Component characterization of Smilax glabra Roxb., and its inhibitory activity against Helicobacter pylori through targeted suppression of its secreted urease

  2025cites this paper
• Comprehensive characterisation of the active ingredients of Smilax glabra Roxb based on chemical fingerprinting, metabolic fingerprinting and pharmacodynamic fingerprinting

  2025cites this paper
• Lipase-catalyzed synthesis of astilbin fatty acid esters: effect of key reaction factors on catalysis and physicochemical properties of target products

  2025cites this paper
• Integrating larval zebrafish model and network pharmacology for screening and identification of edible herbs with therapeutic potential for MAFLD: A promising drug Smilax glabra Roxb.

  2024cites this paper
• Astilbin improves the therapeutic effects of mesenchymal stem cells in AKI-CKD mice by regulating macrophage polarization through PTGS2-mediated pathway

  2024cites this paper
• Therapeutic Effect of Smilax glabra Roxb. on Weaning Rats Against Pb-Induced Nephrotoxicity Based on Network Pharmacology

  2024cites this paper
• Rapid evaluation of the quality of Smilax glabra Roxb. using QADS based on FT-NIR combined with multiple intelligent algorithms.

  2024cites this paper
• Exploring the Phytochemical Diversity and Antioxidant Potential of the Vietnamese Smilax glabra Roxb: Insights from UPLC-QTOF-MS/MS and Zebrafish Model Studies

  2024cites this paper
• Ethnopharmacology of five flowers herbal tea, a popular traditional beverage in Hong Kong and South China

  2024cites this paper
• Integrated network pharmacological analysis revealed that Smilax glabra Roxb. alleviates IMQ-induced psoriatic skin inflammation through regulating T cell immune response.

  2024cites this paper
• Therapeutic effects of traditional Chinese medicine on gouty nephropathy: Based on NF-κB signalingpathways.

  2023cites this paper
• Preparation and characterization of zein–lecithin–total flavonoids from Smilax glabra complex nanoparticles and the study of their antioxidant activity on HepG2 cells

  2023cites this paper
• Flavonoids from Smilax china L. Rhizome improve chronic pelvic inflammatory disease by promoting macrophage reprogramming via the NLRP3 inflammasome-autophagy pathway

  2023cites this paper
• Structural characterization and anti-inflammatory activity of a novel neutral polysaccharide isolated from Smilax glabra Roxb.

  2023cites this paper
• Antimicrobial Activity of Some Medicinal Herbs to the Treatment of Cutaneous and Mucocutaneous Infections: Preliminary Research

  2023cites this paper
• Astilbin Attenuates Cadmium-Induced Adipose Tissue Damage by Inhibiting NF-κB Pathways and Regulating the Expression of HSPs in Chicken

  2022cites this paper
• Integrating network pharmacology and experimental validation to decipher the mechanism of the Chinese herbal prescription JieZe-1 in protecting against HSV-2 infection

  2022cites this paper
• A Short Review on Synthetic Methodologies of Flavonoids

  2022cites this paper
• Smilax glabra Roxb. flavonoids protect against pathological cardiac hypertrophy by inhibiting the Raf/MEK/ERK pathway: In vivo and in vitro studies.

  2022cites this paper
• Astilbin improves pregnancy outcome in rats with recurrent spontaneous abortion by regulating Th1/Th2 balance

  2022cites this paper
• Jiu-Wei-Yong-An Formula suppresses JAK1/STAT3 and MAPK signaling alleviates atopic dermatitis-like skin lesions.

  2022cites this paper
• Flavonoid Group of Smilax glabra Roxb. Regulates the Anti-Tumor Immune Response Through the STAT3/HIF-1 Signaling Pathway

  2022cites this paper
• Traditional Chinese herbs and natural products in hyperuricemia-induced chronic kidney disease

  2022cites this paper
• Influence of heat processing on the anti-inflammatory activity of fresh Smilax glabra based on PDE4 inhibition

  2022cites this paper
• Ethnomedicinal plants of Kuki-Chin tribes in Kaihlam wildlife sanctuary of Manipur, India

  2022cites this paper
• Ganoderma lucidum Spore Polysaccharide Inhibits the Growth of Hepatocellular Carcinoma Cells by Altering Macrophage Polarity and Induction of Apoptosis

  2021cites this paper
• Network Pharmacology Interpretation of Fuzheng–Jiedu Decoction against Colorectal Cancer

  2021cites this paper
• Protective Effects of Smilax glabra Roxb on Carbon Tetrachloride Induced Rat Acute Liver Injury by Inhibiting the Activation of the Nucleotide-Binding Domain Leucine-Rich Repeat Containing Pyrin Domain containing 3 Inflammasome

  2021cites this paper
• Ethnomedicinal study of medicinal plants used by Mizo tribes in Champhai district of Mizoram, India

  2021cites this paper
• Kaempferia galanga L.: Progresses in Phytochemistry, Pharmacology, Toxicology and Ethnomedicinal Uses

  2021cites this paper
• The interaction between gut microbiota and flavonoid extract from Smilax glabra Roxb. and its potent alleviation of fatty liver.

  2021cites this paper
• Protective Effects of Smilax glabra Roxb on Carbon Tetrachloride Induced Rat Acute Liver Injury by Inhibiting the Activation of the NLRP3 Inflammasome

  2021cites this paper
• Partial response to Chinese patent medicine Kangliu pill for adult glioblastoma: A case report and review of the literature

  2021cites this paper
• Vitamin B3-based protic ionic liquids as green solvents for the isolation of astilbin from rhizoma smilacis glabrae

  2020cites this paper
• Transcriptome profiling reveals multiple pathways responsible for the beneficial metabolic effects of Smilax glabra flavonoids in mouse 3T3-L1 adipocytes.

  2020cites this paper
• A Mass Spectrometry Based Metabolite Profiling Workflow for Selecting Abundant Specific Markers and Their Structurally Related Multi-Component Signatures in Traditional Chinese Medicine Multi‐Herb Formulae

  2020cites this paper
• Antioxidant and Anti-Inflammatory Activities of Six Flavonoids from Smilax glabra Roxb

  2020influential citation
• Antibacterial Activity of Four Plant Extracts Extracted from Traditional Chinese Medicinal Plants against Listeria monocytogenes, Escherichia coli, and Salmonella enterica subsp. enterica serovar Enteritidis

  2020cites this paper
• Lei-gong-gen formula granule attenuates hyperlipidemia in rats via cGMP-PKG signaling pathway.

  2020cites this paper
• Ethnobotany, Phytochemistry and Pharmacological Properties of Eucommia ulmoides: A Review.

  2019cites this paper
• Study of pro-angiogenic activity of astilbin on human umbilical vein endothelial cells in vitro and zebrafish in vivo

  2019cites this paper
• Effects of Flavonoids and Its Derivatives on Immune Cell Responses.

  2019cites this paper
• Analysis of Case Studies of Treating Atopic Dermatitis

  2019cites this paper
• Antiviral effect of Chinese herbal prescription JieZe-1 on adhesion and penetration of VK2/E6E7 with herpes simplex viruses type 2

  2019cites this paper
• Traditional Thai herbal medicine as an alternative treatment for refractory chronic eczema.

  2019cites this paper
• Discovering the Combined In-vitro Antiinflammatory Effects of Smilax glabra Standardized Rhizome Extract and Berberis aristata Standardized Root Extract

  2018cites this paper
• Clinical Relevance of Medicinal Plants and Foods of Vegetal Origin on the Activity of Cytochrome P450

  2018cites this paper