Activity of ABCG2 Is Regulated by Its Expression and Localization in DHT and Cyclopamine‐Treated Breast Cancer Cells

No abstract is available for this paper.

• Publication year

  2016

• Venue

  Journal of Cellular Biochemistry

• Publication date

  2016-10-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1002/jcb.25523PMID 26917208
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Mitoxantrone, More than Just Another Topoisomerase II Poison

  2016cited by this paper
• Role of the androgen receptor in triple-negative breast cancer.

  2016cited by this paper
• ABCG2 Localizes to the Nucleus and Modulates CDH1 Expression in Lung Cancer Cells123

  2015influential reference
• Multiple Molecular Subtypes of Triple-Negative Breast Cancer Critically Rely on Androgen Receptor and Respond to Enzalutamide In Vivo

  2015cited by this paper
• Proteasome Failure Promotes Positioning of Lysosomes around the Aggresome via Local Block of Microtubule-Dependent Transport

  2014cited by this paper
• Androgen receptor (AR) expression in 400 breast carcinomas: is routine AR assessment justified?

  2014cited by this paper
• Tackling the cancer stem cells — what challenges do they pose?

  2014cited by this paper
• Cancer drug resistance: an evolving paradigm

  2013influential reference
• The Role of the Androgen Receptor in Triple-Negative Breast Cancer

  2013cited by this paper
• Role of breast cancer resistance protein (BCRP/ABCG2) in cancer drug resistance.

  2012influential reference
• Androgen receptor as a targeted therapy for breast cancer.

  2012cited by this paper
• Xanthines Down-Regulate the Drug Transporter ABCG2 and Reverse Multidrug Resistance

  2012cited by this paper
• Breast cancer resistance protein (BCRP/ABCG2) localises to the nucleus in glioblastoma multiforme cells

  2012cited by this paper
• Hedgehog overexpression is associated with stromal interactions and predicts for poor outcome in breast cancer.

  2011cited by this paper
• Structure and Function of ABCG2-Rich Extracellular Vesicles Mediating Multidrug Resistance

  2011cited by this paper
• GLI1, a crucial mediator of sonic hedgehog signaling in prostate cancer, functions as a negative modulator for androgen receptor.

  2011cited by this paper
• Targeting androgen receptor in estrogen receptor-negative breast cancer.

  2011cited by this paper
• Lysosomal positioning coordinates cellular nutrient responses

  2011cited by this paper
• Hedgehog Signaling Antagonist GDC-0449 (Vismodegib) Inhibits Pancreatic Cancer Stem Cell Characteristics: Molecular Mechanisms

  2011cited by this paper
• Expression of androgen receptors in primary breast cancer.

  2010cited by this paper
• Control of mammary stem cell function by steroid hormone signalling

  2010cited by this paper
• Hedgehog/Gli supports androgen signaling in androgen deprived and androgen independent prostate cancer cells

  2010cited by this paper
• The 44-kDa Pim-1 Kinase Phosphorylates BCRP/ABCG2 and Thereby Promotes Its Multimerization and Drug-resistant Activity in Human Prostate Cancer Cells*

  2008cited by this paper
• Antiproliferative actions of the synthetic androgen, mibolerone, in breast cancer cells are mediated by both androgen and progesterone receptors.

  2008cited by this paper
• MCF7 side population cells with characteristics of cancer stem/progenitor cells express the tumor antigen MUC1.

  2008cited by this paper
• Cancer stem cells in solid tumours: accumulating evidence and unresolved questions

  2008cited by this paper
• Intramolecular Disulfide Bond Is a Critical Check Point Determining Degradative Fates of ATP-binding Cassette (ABC) Transporter ABCG2 Protein*

  2007cited by this paper
• Differential Subcellular Distribution of Mitoxantrone in Relation to Chemosensitization in Two Human Breast Cancer Cell Lines

  2007cited by this paper
• Role of androgens on MCF-7 breast cancer cell growth and on the inhibitory effect of letrozole.

  2006cited by this paper
• Estrogen‐mediated post transcriptional down‐regulation of P‐glycoprotein in MDR1‐transduced human breast cancer cells

  2006cited by this paper
• EGFR Regulates the Side Population in Head and Neck Squamous Cell Carcinoma

  2006cited by this paper
• Novel extracellular vesicles mediate an ABCG2-dependent anticancer drug sequestration and resistance.

  2005cited by this paper
• Side population is enriched in tumorigenic, stem-like cancer cells, whereas ABCG2+ and ABCG2- cancer cells are similarly tumorigenic.

  2005cited by this paper
• Inhibition of MCF-7 breast cancer cell proliferation by 5alpha-dihydrotestosterone; a role for p21(Cip1/Waf1).

  2004cited by this paper
• Hedgehog Signaling Pathway is a New Therapeutic Target for Patients with Breast Cancer

  2004cited by this paper
• Inhibition of MCF-7 breast cancer cell proliferation by 5-dihydrotestosterone; a role for p21 Cip1/Waf1

  2004cited by this paper
• Repeated observation of breast tumor subtypes in independent gene expression data sets

  2003cited by this paper
• Prospective identification of tumorigenic breast cancer cells

  2003cited by this paper
• Hassles with Taking Out the Garbage: Aggravating Aggresomes

  2002cited by this paper
• The multidrug resistance transporter ABCG2 (breast cancer resistance protein 1) effluxes Hoechst 33342 and is overexpressed in hematopoietic stem cells.

  2002cited by this paper
• A new mathematical model for relative quantification in real-time RT-PCR.

  2001cited by this paper
• Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications

  2001cited by this paper
• The multidrug-resistant phenotype associated with overexpression of the new ABC half-transporter, MXR (ABCG2).

  2000cited by this paper
• Androgens induce divergent proliferative responses in human breast cancer cell lines.

  1995cited by this paper

• Regulation of ABC transporters by sex steroids may explain differences in drug resistance between sexes

  2023cites this paper
• IMAGGS: a radiogenomic framework for identifying multi-way associations in breast cancer subtypes.

  2023cites this paper
• Molecular Docking Insights of Newly Synthesized Schiff Base Monomers and Evaluating the Anticancer Activity of Their Polymers

  2023cites this paper
• In silico screening of alkaloids as potential inhibitors of HER2 protein for breast cancer treatment

  2023cites this paper
• Benzoyl indoles with metabolic stability as reversal agents for ABCG2-mediated multidrug resistance.

  2019cites this paper
• Role of cancer stem cells in breast and prostate cancer

  2016cites this paper
• Research Resources for Nuclear Receptor Signaling Pathways

  2016cites this paper