BRCA1/BARD1 E3 Ubiquitin Ligase Can Modify Histones H2A and H2B in the Nucleosome Particle

No abstract is available for this paper.

• Publication year

  2010

• Venue

  Journal of Biomolecular Structure and Dynamics

• Publication date

  2010-02-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1080/07391102.2010.10507326PMID 19916563
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Chemically ubiquitylated histone H2B stimulates hDot1L-mediated intranucleosomal methylation

  2008cited by this paper
• Histone ubiquitination: triggering gene activity.

  2008cited by this paper
• H2B-K123 ubiquitination stimulates RNAPII elongation independent of H3-K4 methylation.

  2007cited by this paper
• H2B ubiquitylation in transcriptional control: a FACT-finding mission.

  2007cited by this paper
• Ubiquitylation of histone H2B controls RNA polymerase II transcription elongation independently of histone H3 methylation.

  2007cited by this paper
• The role of BRCA1 in transcriptional regulation and cell cycle control

  2006cited by this paper
• Histone ubiquitylation and the regulation of transcription.

  2006cited by this paper
• BRCA1-Mediated Ubiquitylation

  2006cited by this paper
• Substrates of the BRCA1-dependent ubiquitin ligase

  2006cited by this paper
• Regulation of histone H2A and H2B ubiquitylation.

  2006cited by this paper
• Histone H2B monoubiquitination functions cooperatively with FACT to regulate elongation by RNA polymerase II.

  2006cited by this paper
• BRCA1 ubiquitylation of CtIP: Just the tIP of the iceberg?

  2006cited by this paper
• Fast, long-range, reversible conformational fluctuations in nucleosomes revealed by single-pair fluorescence resonance energy transfer.

  2005cited by this paper
• Monoubiquitination of human histone H2B: the factors involved and their roles in HOX gene regulation.

  2005cited by this paper
• The human homolog of yeast BRE1 functions as a transcriptional coactivator through direct activator interactions.

  2005cited by this paper
• Role of Bmi-1 and Ring1A in H2A ubiquitylation and Hox gene silencing.

  2005cited by this paper
• BRCA1-dependent ubiquitination of gamma-tubulin regulates centrosome number.

  2004cited by this paper
• Focused Review Series : BRCA 1 at 10 Years Since Discovery

  2004cited by this paper
• BRCA1-Dependent Ubiquitination of γ-Tubulin Regulates Centrosome Number

  2004cited by this paper
• Role of histone H2A ubiquitination in Polycomb silencing

  2004cited by this paper
• The Rtf1 Component of the Paf1 Transcriptional Elongation Complex Is Required for Ubiquitination of Histone H2B*

  2003cited by this paper
• A conserved RING finger protein required for histone H2B monoubiquitination and cell size control.

  2003cited by this paper
• Bre1, an E3 ubiquitin ligase required for recruitment and substrate selection of Rad6 at a promoter.

  2003cited by this paper
• The multiple nuclear functions of BRCA1: transcription, ubiquitination and DNA repair.

  2003cited by this paper
• Ubiquitination of histone H2B regulates H3 methylation and gene silencing in yeast

  2002cited by this paper
• Methylation of Histone H3 by COMPASS Requires Ubiquitination of Histone H2B by Rad6*

  2002cited by this paper
• Gene silencing: Trans-histone regulatory pathway in chromatin

  2002cited by this paper
• Autoubiquitination of the BRCA1·BARD1 RING Ubiquitin Ligase*

  2002cited by this paper
• Activation of the E3 ligase function of the BRCA1/BARD1 complex by polyubiquitin chains

  2002cited by this paper
• The RING Heterodimer BRCA1-BARD1 Is a Ubiquitin Ligase Inactivated by a Breast Cancer-derived Mutation*

  2001cited by this paper
• BRCA1-induced large-scale chromatin unfolding and allele-specific effects of cancer-predisposing mutations

  2001cited by this paper
• Rad6-dependent ubiquitination of histone H2B in yeast.

  2000cited by this paper
• CBP/p300 interact with and function as transcriptional coactivators of BRCA1.

  2000cited by this paper
• BRCA1 is associated with a human SWI/SNF-related complex: linking chromatin remodeling to breast cancer.

  2000cited by this paper
• In search of the tumour-suppressor functions of BRCA1 and BRCA2

  2000cited by this paper
• Expression and purification of recombinant histones and nucleosome reconstitution.

  1999cited by this paper
• BRCA1 interacts with components of the histone deacetylase complex.

  1999cited by this paper
• DNA at the entry-exit of the nucleosome observed by cryoelectron microscopy.

  1995cited by this paper
• Octamer displacement and redistribution in transcription of single nucleosomes.

  1994cited by this paper
• Effects of histone acetylation, ubiquitination and variants on nucleosome stability.

  1993cited by this paper
• Chromatin reconstitution on small DNA rings. III. Histone H5 dependence of DNA supercoiling in the nucleosome.

  1990cited by this paper
• Homogeneous reconstituted oligonucleosomes, evidence for salt-dependent folding in the absence of histone H1.

  1989cited by this paper
• Chromatin reconstituted from tandemly repeated cloned DNA fragments and core histones: a model system for study of higher order structure.

  1985cited by this paper
• Isopeptide linkage between nonhistone and histone 2A polypeptides of chromosomal conjugate-protein A24.

  1977cited by this paper
• Isolation and characterization of protein A24, a "histone-like" non-histone chromosomal protein.

  1975cited by this paper

• Beyond repair: Expanding roles of BRCA1 in RNA processing and cancer.

  2025cites this paper
• Molecular dynamics simulations reveal the effect of mutations in the RING domains of BRCA1-BARD1 complex and its relevance to the prognosis of breast cancer

  2023cites this paper
• BRCA1 promoter methylation & its immunohistochemical correlation in sporadic breast cancer

  2023cites this paper
• In silico investigation on the mutational analysis of BRCA1-BARD1 RING domains and its effect on nucleosome recognition and ubiquitination.

  2023cites this paper
• Differential requirement for BRCA1-BARD1 E3 ubiquitin ligase activity in DNA damage repair and meiosis in the Caenorhabditis elegans germ line

  2022influential citation
• Histone Tail Electrostatics Modulate E2-E3 Enzyme Dynamics: A Gateway to Regulate Ubiquitination Machinery

  2022cites this paper
• Control of Genome through Variative Nature of Histone-Modifying Ubiquitin Ligases

  2021cites this paper
• The fellowship of the RING: BRCA1, its partner BARD1 and their liaison in DNA repair and cancer.

  2021cites this paper
• Homologous recombination in mammalian cells: From molecular mechanisms to pathology

  2021cites this paper
• Expression of BARD1 β Isoform in Selected Pediatric Tumors

  2021cites this paper
• The Effects of Genetic and Epigenetic Alterations of BARD1 on the Development of Non-Breast and Non-Gynecological Cancers

  2020cites this paper
• BRCA1/BARD1 site-specific ubiquitylation of nucleosomal H2A is directed by BARD1

  2020cites this paper
• Histone Monoubiquitination in Chromatin Remodelling: Focus on the Histone H2B Interactome and Cancer

  2020cites this paper
• 1 BARD 1 and breast cancer : the possibility of creating 2 screening tests and new preventive and therapeutic 3 pathways for predisposed women 4

  2020cites this paper
• BRCA1 Mutations in Cancer: Coordinating Deficiencies in Homologous Recombination with Tumorigenesis

  2020cites this paper
• Homologous repair deficiency score for identifying breast cancers with defective DNA damage response

  2020cites this paper
• The association between the methylation frequency of BRCA1/2 gene promoter and occurrence and prognosis of breast carcinoma

  2020cites this paper
• Crosstalk of intracellular post-translational modifications in cancer.

  2019cites this paper
• Writing Histone Monoubiquitination in Human Malignancy—The Role of RING Finger E3 Ubiquitin Ligases

  2019cites this paper
• BRCA1/BARD1-dependent ubiquitination of NF2 regulates Hippo-YAP1 signaling

  2019cites this paper
• LncRNA ODIR1 inhibits osteogenic differentiation of hUC-MSCs through the FBXO25/H2BK120ub/H3K4me3/OSX axis

  2019cites this paper
• BARD1 is necessary for ubiquitylation of nucleosomal histone H2A and for transcriptional regulation of estrogen metabolism genes

  2018cites this paper
• BRCA1-Dependent Transcriptional Regulation: Implication in Tissue-Specific Tumor Suppression

  2018cites this paper
• Hunter College 11-27-2017 mRNA Processing Factor CstF-50 and Ubiquitin Escort Factor p 97 Are BRCA 1 / BARD 1 Cofactors Involved in Chromatin Remodeling during the DNA Damage Response

  2018cites this paper
• mRNA Processing Factor CstF-50 and Ubiquitin Escort Factor p97 Are BRCA1/BARD1 Cofactors Involved in Chromatin Remodeling during the DNA Damage Response

  2017cites this paper
• The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery

  2017cites this paper
• Small-Molecule Inhibitors Targeting DNA Repair and DNA Repair Deficiency in Research and Cancer Therapy.

  2017cites this paper
• New concepts on BARD1: Regulator of BRCA pathways and beyond.

  2016cites this paper
• The RING finger domain E3 ubiquitin ligases BRCA1 and the RNF20/RNF40 complex in global loss of the chromatin mark histone H2B monoubiquitination (H2Bub1) in cell line models and primary high-grade serous ovarian cancer.

  2016cites this paper
• Histone H2B monoubiquitination is a critical epigenetic switch for the regulation of autophagy

  2016cites this paper
• Chemical “Diversity” of Chromatin Through Histone Variants and Histone Modifications

  2015cites this paper
• RNF20-SNF2H Pathway of Chromatin Relaxation in DNA Double-Strand Break Repair

  2015cites this paper
• Chapter 26 – Epigenetics of Cisplatin Resistance

  2015cites this paper
• Histone monoubiquitination by Clock–Bmal1 complex marks Per1 and Per2 genes for circadian feedback

  2015cites this paper
• The Polycomb Repressive Complex 1 Protein BMI1 Is Required for Constitutive Heterochromatin Formation and Silencing in Mammalian Somatic Cells*

  2015cites this paper
• Histone H2B monoubiquitination: roles to play in human malignancy.

  2015influential citation
• Cooperation between BRCA1 and vitamin D is critical for histone acetylation of the p21waf1 promoter and for growth inhibition of breast cancer cells and cancer stem-like cells

  2014cites this paper
• Recent advances in defining the ubiquitylome

  2014cites this paper
• The role of the BARD1 BRCT domains in the DNA damage response

  2014cites this paper
• Cooperation between BRCA 1 and vitamin D is critical for histone acetylation of the p 21 waf 1 promoter and for growth inhibition of breast cancer cells and cancer stem-like cells

  2014cites this paper
• Tyrosine phosphorylation of histone H2A by CK2 regulates transcriptional elongation

  2014cites this paper
• Writing and reading H2B monoubiquitylation.

  2014cites this paper
• UNIVERSITY OF CALIFORNIA, SAN DIEGO Tyrosine phosphorylation of histone H2A by CK2 regulates transcriptional elongation and DNA damage repair A dissertation submitted in partial satisfaction of the requirements for the degree Doctor of Philosophy in Biomedical Sciences by

  2014cites this paper
• Chromatin Dynamics during Lytic Infection with Herpes Simplex Virus 1

  2013influential citation
• Validation of a Gene-Expression Based Assay for BRCA1 Function

  2013cites this paper
• Links between genome integrity and BRCA1 tumor suppression.

  2012influential citation
• Histone H2B ubiquitin ligases RNF20 and RNF40 in androgen signaling and prostate cancer cell growth.

  2012cites this paper
• BARD1: An independent predictor of survival in non‐small cell lung cancer

  2012cites this paper
• Histone ubiquitylation and chromatin dynamics.

  2012cites this paper
• A DNA Repair Protein BRCA1 as a Potentially Molecular Target for the Anticancer Platinum Drug Cisplatin

  2011influential citation
• Tumor and Stem Cell Biology BRCA 1 Counteracts Progesterone Action by Ubiquitination Leading to Progesterone Receptor Degradation and Epigenetic Silencing of Target Promoters

  2011cites this paper
• Characterisation of histone modifications at insulator elements

  2011cites this paper
• Substitution of aspartic acid with glutamic acid at position 67 of the BRCA1 RING domain retains ubiquitin ligase activity and zinc(II) binding with a reduced transition temperature

  2011cites this paper
• DNA damage response: the emerging role of c-Abl as a regulatory switch?

  2011cites this paper
• BRCA1 counteracts progesterone action by ubiquitination leading to progesterone receptor degradation and epigenetic silencing of target promoters.

  2011cites this paper
• Cdk1 and BRCA1 target γ-tubulin to microtubule domains.

  2011cites this paper
• Protein-Protein Interactions: Principles, Techniques, and their Potential Role in New Drug Development

  2011cites this paper
• Predicting Sumoylation Site by Feature Selection Method

  2011cites this paper
• System-Level Analysis of Neuroblastoma Tumor–Initiating Cells Implicates AURKB as a Novel Drug Target for Neuroblastoma

  2010cites this paper
• Analyse de l'expression de BARD1 dans le cancer du poumon et le cancer colorectal

  2010cites this paper