Probucol attenuates overt pain-like behavior and carrageenan-induced inflammatory hyperalgesia and leukocyte recruitment by inhibiting NF-кB activation and cytokine production without antioxidant effects

No abstract is available for this paper.

• Publication year

  2017

• Venue

  Inflammation Research

• Publication date

  2017-04-06

• Fields of study

  Medicine

• Identifiers
  DOI 10.1007/s00011-017-1040-8PMID 28386622
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Inflammatory

  2020cited by this paper
• Naringenin reduces inflammatory pain in mice.

  2016cited by this paper
• An Analysis of the Number of Medical Malpractice Claims and Their Amounts

  2016cited by this paper
• Naringenin Inhibits Superoxide Anion-Induced Inflammatory Pain: Role of Oxidative Stress, Cytokines, Nrf-2 and the NO−cGMP−PKG−KATPChannel Signaling Pathway

  2016cited by this paper
• Pimaradienoic Acid Inhibits Carrageenan-Induced Inflammatory Leukocyte Recruitment and Edema in Mice: Inhibition of Oxidative Stress, Nitric Oxide and Cytokine Production

  2016cited by this paper
• Spinal cord oligodendrocyte‐derived alarmin IL‐33 mediates neuropathic pain

  2016cited by this paper
• Neuroimmunity: Physiology and Pathology.

  2016cited by this paper
• The citrus flavonone naringenin reduces lipopolysaccharide-induced inflammatory pain and leukocyte recruitment by inhibiting NF-κB activation.

  2016cited by this paper
• Curcumin inhibits superoxide anion-induced pain-like behavior and leukocyte recruitment by increasing Nrf2 expression and reducing NF-κB activation

  2015cited by this paper
• Vinpocetine Reduces Carrageenan-Induced Inflammatory Hyperalgesia in Mice by Inhibiting Oxidative Stress, Cytokine Production and NF-κB Activation in the Paw and Spinal Cord

  2015cited by this paper
• Probucol Prevents Atrial Remodeling by Inhibiting Oxidative Stress and TNF‐α/NF‐κB/TGF‐β Signal Transduction Pathway in Alloxan‐Induced Diabetic Rabbits

  2015cited by this paper
• Vinpocetine reduces lipopolysaccharide-induced inflammatory pain and neutrophil recruitment in mice by targeting oxidative stress, cytokines and NF-κB.

  2015cited by this paper
• Circulating microRNAs in Sera Correlate with Soluble Biomarkers of Immune Activation but Do Not Predict Mortality in ART Treated Individuals with HIV-1 Infection: A Case Control Study

  2015cited by this paper
• The superoxide anion donor, potassium superoxide, induces pain and inflammation in mice through production of reactive oxygen species and cyclooxygenase-2

  2015cited by this paper
• Probucol suppresses macrophage infiltration and MMP expression in atherosclerotic plaques of WHHL rabbits.

  2014cited by this paper
• Differential regulation of peripheral IL‐1&bgr;‐induced mechanical allodynia and thermal hyperalgesia in rats

  2014cited by this paper
• Effects of probucol on angiotensin II-induced BMP-2 expression in human umbilical vein endothelial cells.

  2013cited by this paper
• Probucol Increases Striatal Glutathione Peroxidase Activity and Protects against 3-Nitropropionic Acid-Induced Pro-Oxidative Damage in Rats

  2013cited by this paper
• Analgesic activity of piracetam: effect on cytokine production and oxidative stress.

  2013cited by this paper
• Probucol inhibits the initiation of atherosclerosis in cholesterol-fed rabbits

  2013cited by this paper
• Involvement of toll-like receptor 2 and 4 in association between dyslipidemia and osteoclast differentiation in apolipoprotein E deficient rat periodontium

  2013cited by this paper
• αB-crystallin/HspB5 regulates endothelial–leukocyte interactions by enhancing NF-κB-induced up-regulation of adhesion molecules ICAM-1, VCAM-1 and E-selectin

  2013cited by this paper
• IL‐33/ST2 signalling contributes to carrageenin‐induced innate inflammation and inflammatory pain: role of cytokines, endothelin‐1 and prostaglandin E2

  2013cited by this paper
• Active Video Games and Health Indicators in Children and Youth: A Systematic Review

  2013cited by this paper
• Netrin-1 regulates the inflammatory response of neutrophils and macrophages, and suppresses ischemic acute kidney injury by inhibiting COX-2 mediated PGE2 production

  2012cited by this paper
• 11 b-Hydroxysteroid dehydrogenase type 1 : potential therapeutic target for metabolic syndrome

  2012cited by this paper
• Kaurenoic acid from Sphagneticola trilobata Inhibits Inflammatory Pain: effect on cytokine production and activation of the NO-cyclic GMP-protein kinase G-ATP-sensitive potassium channel signaling pathway.

  2012cited by this paper
• Prostaglandin E2 and pain--an update.

  2011cited by this paper
• Acetaldehyde-Mediated Neurotoxicity: Relevance to Fetal Alcohol Spectrum Disorders

  2011cited by this paper
• Probucol Attenuates Oxidative Stress, Energy Starvation, and Nitric Acid Production Following Transient Forebrain Ischemia in the Rat Hippocampus

  2011cited by this paper
• Probucol attenuates inflammation and increases stability of vulnerable atherosclerotic plaques in rabbits.

  2011cited by this paper
• Small-molecule screen identifies reactive oxygen species as key regulators of neutrophil chemotaxis

  2010cited by this paper
• Chlorogenic acid attenuates adhesion molecules upregulation in IL-1β-treated endothelial cells

  2010influential reference
• The cumulative burden of oral corticosteroid side effects and the economic implications of steroid use.

  2009cited by this paper
• Effects of probucol on hepatic tumor necrosis factor‐α, interleukin‐6 and adiponectin receptor‐2 expression in diabetic rats

  2009cited by this paper
• New regulators of NF-κB in inflammation

  2008cited by this paper
• Neutrophil Migration Induced by IL-1β Depends upon LTB4 Released by Macrophages and upon TNF-α and IL-1β Released by Mast Cells

  2008influential reference
• Role of IL-18 in overt pain-like behaviour in mice.

  2008cited by this paper
• Neutrophil migration induced by IL-1beta depends upon LTB4 released by macrophages and upon TNF-alpha and IL-1beta released by mast cells.

  2008cited by this paper
• Origin and physiological roles of inflammation

  2008cited by this paper
• Nociceptors Are Interleukin-1β Sensors

  2008cited by this paper
• Phosphorylation of Sodium Channel Nav1.8 by p38 Mitogen-Activated Protein Kinase Increases Current Density in Dorsal Root Ganglion Neurons

  2008cited by this paper
• Anti-inflammatory and side effects of cyclooxygenase inhibitors.

  2007cited by this paper
• Beneficial synergistic effects of concurrent treatment with cilostazol and probucol against focal cerebral ischemic injury in rats.

  2007cited by this paper
• Hypernociceptive role of cytokines and chemokines: targets for analgesic drug development?

  2006cited by this paper
• Cryopyrin activates the inflammasome in response to toxins and ATP

  2006cited by this paper
• Toll-like receptors and innate immunity

  2006cited by this paper
• NF-kappaB regulates phagocytic NADPH oxidase by inducing the expression of gp91phox.

  2006cited by this paper
• Acute p38-mediated modulation of tetrodotoxin-resistant sodium channels in mouse sensory neurons by tumor necrosis factor-alpha.

  2006cited by this paper
• NF-κB Regulates Phagocytic NADPH Oxidase by Inducing the Expression of gp91phox*

  2006influential reference
• Acute p38-Mediated Modulation of Tetrodotoxin-Resistant Sodium Channels in Mouse Sensory Neurons by Tumor Necrosis Factor-α

  2006cited by this paper
• Impaired inflammatory angiogenesis, but not leukocyte influx, in mice lacking TNFR1

  2005cited by this paper
• A cascade of cytokines mediates mechanical inflammatory hypernociception in mice.

  2005cited by this paper
• An electronic pressure-meter nociception paw test for mice.

  2004cited by this paper
• Buprenorphine: a unique drug with complex pharmacology.

  2004cited by this paper
• An electronic pressure-meter nociception paw test for rats.

  2004cited by this paper
• Discovery of novel phenolic antioxidants as inhibitors of vascular cell adhesion molecule-1 expression for use in chronic inflammatory diseases.

  2004cited by this paper
• Ginkgo biloba Extract Inhibits Tumor Necrosis Factor-&agr;–Induced Reactive Oxygen Species Generation, Transcription Factor Activation, and Cell Adhesion Molecule Expression in Human Aortic Endothelial Cells

  2003cited by this paper
• Ginkgo biloba Extract Inhibits Tumor Necrosis Factor-α–Induced Reactive Oxygen Species Generation, Transcription Factor Activation, and Cell Adhesion Molecule Expression in Human Aortic Endothelial Cells

  2003influential reference
• Probucol restores the defective leukocyte-endothelial interaction in experimental diabetes.

  2003cited by this paper
• Ginkgo biloba extract inhibits tumor necrosis factor-alpha-induced reactive oxygen species generation, transcription factor activation, and cell adhesion molecule expression in human aortic endothelial cells.

  2003cited by this paper
• Endothelial Apoptosis Induced by Oxidative Stress Through Activation of NF-&kgr;B: Antiapoptotic Effect of Antioxidant Agents on Endothelial Cells

  2001cited by this paper
• Interleukin-1β-mediated induction of Cox-2 in the CNS contributes to inflammatory pain hypersensitivity

  2001cited by this paper
• Toll-like receptors and innate immunity

  2001cited by this paper
• Probucol inhibits lipid peroxidation of macrophage and affects its secretory properties.

  2000cited by this paper
• Selective inhibition by alpha-tocopherol of vascular cell adhesion molecule-1 expression in human vascular endothelial cells.

  2000influential reference
• Selective Inhibition by α-Tocopherol of Vascular Cell Adhesion Molecule-1 Expression in Human Vascular Endothelial Cells

  2000cited by this paper
• Phospholipase A2 activity in ox-LDL-stimulated mesangial cells and modulation by α-tocopherol

  1999cited by this paper
• Phospholipase A2 activity in ox-LDL-stimulated mesangial cells and modulation by alpha-tocopherol.

  1999cited by this paper
• Probucol Inhibits Neointimal Formation in Carotid Arteries of Normocholesterolemic Rabbits and the Proliferation of Cultured Rabbit Vascular Smooth Muscle Cells

  1998cited by this paper
• Antinociceptive effect of meloxicam, in neurogenic and inflammatory nociceptive models in mice

  1998cited by this paper
• TNF-alpha and IL-1 upregulate membrane-bound and soluble E-selectin through a common pathway.

  1997influential reference
• TNF-α and IL-1 Upregulate Membrane-Bound and Soluble E-Selectin through a Common Pathway

  1997cited by this paper
• Probucol downregulates E-selectin expression on cultured human vascular endothelial cells.

  1996cited by this paper
• Probucol promotes endogenous antioxidants and provides protection against adriamycin-induced cardiomyopathy in rats.

  1994cited by this paper
• Probucol inhibits mononuclear cell adhesion to vascular endothelium in the cholesterol-fed rabbit.

  1993cited by this paper
• Inhibition of IL-1 beta expression in THP-1 cells by probucol and tocopherol.

  1991cited by this paper
• Probucol, a superoxide free radical scavenger in vitro.

  1991cited by this paper
• Inhibition of IL-1β expression in THP-1 cells by probucol and tocopherol

  1991cited by this paper
• Ex vivo lipopolysaccharide‐induced interleukiri‐1 secretion from murine peritoneal macrophages inhibited by probucol, a hypocholesterolemic agent with antioxidant properties

  1990cited by this paper
• Inhibition by probucol of interleukin 1 secretion and its implication in atherosclerosis.

  1988cited by this paper
• Cellular and extracellular myeloperoxidase in pyogenic inflammation

  1982cited by this paper
• Cellular and extracellular myeloperoxidase in pyogenic inflammation.

  1982cited by this paper
• International Journal of Molecular Sciences the Emergence of the Dose–response Concept in Biology and Medicine

  year unknowncited by this paper

• Astaxanthin attenuates carrageenan-induced oxidative stress and inflammation in mice brain: possible role of the wnt/β-catenin signaling pathway

  2025cites this paper
• A new semi-synthetic carboximidamide mitigates sickness behavior in mice.

  2025cites this paper
• SARM1 in the pathogenesis of immune-related disease.

  2024cites this paper
• Probucol is anti-hyperalgesic in a mouse peripheral nerve injury model of neuropathic pain

  2023cites this paper
• Fermented (By Monascus purpureus or Aspergillus oryzae) and Non-Fermented Defatted Soybean Flour Extracts: Biological Insight and Mechanism Differences in Inflammatory Pain and Peritonitis

  2023cites this paper
• From Initiation to Maintenance: HIV-1 Gp120-induced Neuropathic Pain Exhibits Different Molecular Mechanisms in the Mouse Spinal Cord Via Bioinformatics Analysis Based on RNA Sequencing

  2022cites this paper
• Effect of nanostructured lipid carriers on transdermal delivery of tenoxicam in irradiated rats

  2020cites this paper
• VF-13, a chimeric peptide of VD-hemopressin(α) and neuropeptide VF, produces potent antinociception with reduced cannabinoid-related side effects.

  2020cites this paper
• Probucol Ameliorates Complete Freund’s Adjuvant-Induced Hyperalgesia by Targeting Peripheral and Spinal Cord Inflammation

  2019cites this paper
• Celastrol attenuates incision‐induced inflammation and pain associated with inhibition of the NF‐&kgr;B signalling pathway via SARM

  2018cites this paper