Hierarchical glucocorticoid-endocannabinoid interplay regulates the activation of the nucleus accumbens by insulin.

No abstract is available for this paper.

• Publication year

  2016

• Venue

  Brain Research Bulletin

• Publication date

  2016-06-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1016/j.brainresbull.2016.05.009PMID 27208730PMCID PMC8041101
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Separate Circuitries Encode the Hedonic and Nutritional Values of Sugar

  2016cited by this paper
• CB1 antagonism produces behaviors more consistent with satiety than reduced reward value in food-maintained responding in rats

  2016cited by this paper
• Stress-induced mechanisms in mental illness: A role for glucocorticoid signalling.

  2016cited by this paper
• Minireview: Food for thought: regulation of synaptic function by metabolic hormones.

  2015cited by this paper
• Lack of presynaptic interaction between glucocorticoid and CB1 cannabinoid receptors in GABA- and glutamatergic terminals in the frontal cortex of laboratory rodents.

  2015cited by this paper
• Direct neuronal glucose uptake heralds activity-dependent increases in cerebral metabolism

  2015cited by this paper
• Multiple Forms of Endocannabinoid and Endovanilloid Signaling Regulate the Tonic Control of GABA Release

  2015cited by this paper
• Presynaptic adenosine A2A receptors dampen cannabinoid CB1 receptor‐mediated inhibition of corticostriatal glutamatergic transmission

  2015cited by this paper
• Insulin enhances striatal dopamine release by activating cholinergic interneurons and thereby signals reward

  2015cited by this paper
• Experimental design and analysis and their reporting: new guidance for publication in BJP

  2015influential reference
• Insulin Action in the Human Brain: Evidence from Neuroimaging Studies

  2015cited by this paper
• Cannabinoid modulation of drug reward and the implications of marijuana legalization.

  2015cited by this paper
• Adenosine A2B receptor activation stimulates glucose uptake in the mouse forebrain

  2015cited by this paper
• Direct evidence for activity-dependent glucose phosphorylation in neurons with implications for the astrocyte-to-neuron lactate shuttle

  2014cited by this paper
• Parsing the players: 2‐arachidonoylglycerol synthesis and degradation in the CNS

  2014cited by this paper
• Enhanced nicotine self‐administration and suppressed dopaminergic systems in a rat model of diabetes

  2014cited by this paper
• GABAergic Neurogliaform Cells Represent Local Sources of Insulin in the Cerebral Cortex

  2014cited by this paper
• Feelings about food: the ventral tegmental area in food reward and emotional eating.

  2014cited by this paper
• A peripheral endocannabinoid mechanism contributes to glucocorticoid-mediated metabolic syndrome

  2014cited by this paper
• Insulin Action in Brain Regulates Systemic Metabolism and Brain Function

  2014influential reference
• CRMP2 Tethers Kainate Receptor Activity to Cytoskeleton Dynamics during Neuronal Maturation

  2013cited by this paper
• Neutral antagonism at the cannabinoid 1 receptor: a safer treatment for obesity

  2013cited by this paper
• Presynaptic TRPV1 vanilloid receptor function is age- but not CB1 cannabinoid receptor-dependent in the rodent forebrain.

  2013cited by this paper
• Insulin induces long-term depression of VTA dopamine neurons via an endocannabinoid-mediated mechanism

  2013cited by this paper
• Presynaptic TRPV1 vanilloid receptor function is age- but not CB1 cannabinoid receptor- dependent in the rodent forebrain

  2013cited by this paper
• Insulin in the Brain: Sources, Localization and Functions

  2013cited by this paper
• Endocannabinoid system and drug addiction: new insights from mutant mice approaches.

  2013cited by this paper
• Effect of insulin on excitatory synaptic transmission onto dopamine neurons of the ventral tegmental area in a mouse model of hyperinsulinemia

  2013cited by this paper
• [Volume changes of cortical and subcortical reward circuitry in the brain of patients with type 2 diabetes mellitus].

  2013cited by this paper
• Impaired hippocampal glucoregulation in the cannabinoid CB1 receptor knockout mice as revealed by an optimized in vitro experimental approach.

  2012cited by this paper
• Insulin in Central Nervous System: More than Just a Peripheral Hormone

  2012cited by this paper
• Cannabinoid CB1 receptors transactivate multiple receptor tyrosine kinases and regulate serine/threonine kinases to activate ERK in neuronal cells

  2012influential reference
• Cannabinoids Induce Pancreatic β-Cell Death by Directly Inhibiting Insulin Receptor Activation

  2012influential reference
• Leptin and insulin pathways in POMC and AgRP neurons that modulate energy balance and glucose homeostasis

  2012cited by this paper
• Multiple functions of endocannabinoid signaling in the brain.

  2012cited by this paper
• Cannabinoid receptor 1-expressing neurons in the nucleus accumbens

  2012cited by this paper
• Brain Deletion of Insulin Receptor Substrate 2 Disrupts Hippocampal Synaptic Plasticity and Metaplasticity

  2012cited by this paper
• Diabetes induces early transient changes in the content of vesicular transporters and no major effects in neurotransmitter release in hippocampus and retina.

  2011cited by this paper
• Common cellular and molecular mechanisms in obesity and drug addiction

  2011influential reference
• Alterations in corticolimbic dendritic morphology and emotional behavior in cannabinoid CB1 receptor-deficient mice parallel the effects of chronic stress.

  2011influential reference
• Insulin signaling and addiction.

  2011cited by this paper
• Effects of Insulin on Brain Glucose Metabolism in Impaired Glucose Tolerance

  2011cited by this paper
• Hippocampal memory processes are modulated by insulin and high-fat-induced insulin resistance.

  2010cited by this paper
• Guidelines for reporting experiments involving animals: the ARRIVE guidelines

  2010cited by this paper
• Animal Research: Reporting In Vivo Experiments: The ARRIVE Guidelines

  2010influential reference
• Endocannabinoids: The silent partner of glucocorticoids in the synapse

  2009cited by this paper
• Neurochemical evidence that stimulation of CB1 cannabinoid receptors on GABAergic nerve terminals activates the dopaminergic reward system by increasing dopamine release in the rat nucleus accumbens.

  2009influential reference
• Regulation of CB1 cannabinoid receptor trafficking by the adaptor protein AP‐3

  2008cited by this paper
• Overlapping neuronal circuits in addiction and obesity: evidence of systems pathology

  2008influential reference
• Stress and glucocorticoid footprints in the brain-the path from depression to Alzheimer's disease.

  2008cited by this paper
• Endocannabinoids in Energy Homeostasis and Metabolic Disorders

  2008cited by this paper
• A novel, rapid, inhibitory effect of insulin on alpha1beta2gamma2s gamma-aminobutyric acid type A receptors.

  2008cited by this paper
• Visualization of 2‐arachidonoylglycerol accumulation and cannabinoid CB1 receptor activity in rat brain cryosections by functional autoradiography

  2007cited by this paper
• Pituitary–adrenocortical axis, serum serotonin and biochemical response after halothane or isoflurane anaesthesia in rabbits

  2007cited by this paper
• Subcellular localization of type 1 cannabinoid receptors in the rat basal ganglia.

  2006cited by this paper
• The unfolding cannabinoid story on energy homeostasis: central or peripheral site of action?

  2006cited by this paper
• Attenuation of Insulin-Evoked Responses in Brain Networks Controlling Appetite and Reward in Insulin Resistance

  2006influential reference
• Targeting dopamine D2 and cannabinoid‐1 (CB1) receptors in rat nucleus accumbens

  2006cited by this paper
• Insulin regulates neuronal glucose uptake by promoting translocation of glucose transporter GLUT3.

  2006cited by this paper
• Insulin and leptin induce Glut4 plasma membrane translocation and glucose uptake in a human neuronal cell line by a phosphatidylinositol 3-kinase- dependent mechanism.

  2006cited by this paper
• Role of brain insulin receptor in control of body weight and reproduction.

  2006cited by this paper
• Inverse agonism and neutral antagonism at cannabinoid CB1 receptors.

  2005cited by this paper
• Involvement of Cannabinoid Receptors in the Regulation of Neurotransmitter Release in the Rodent Striatum: A Combined Immunochemical and Pharmacological Analysis

  2005cited by this paper
• Fast food, central nervous system insulin resistance, and obesity.

  2005cited by this paper
• Rapid glucocorticoid-mediated endocannabinoid release and opposing regulation of glutamate and gamma-aminobutyric acid inputs to hypothalamic magnocellular neurons.

  2005cited by this paper
• An investigation into signal transduction mechanisms involved in insulin‐induced long‐term depression in the CA1 region of the hippocampus

  2004cited by this paper
• Nongenomic Glucocorticoid Inhibition via Endocannabinoid Release in the Hypothalamus: A Fast Feedback Mechanism

  2003influential reference
• Exogenous and Endogenous Cannabinoids Control Synaptic Transmission in Mice Nucleus Accumbens

  2003cited by this paper
• Signaling Effects of Demethylasterriquinone B1, a Selective Insulin Receptor Modulator

  2003cited by this paper
• The role of insulin in human brain glucose metabolism: an 18fluoro-deoxyglucose positron emission tomography study.

  2002cited by this paper
• Corticosteroids and cognition.

  2001cited by this paper
• Dexamethasone-induced insulin resistance and pancreatic adaptive response in aging rats are not modified by oral vanadyl sulfate treatment.

  2001cited by this paper
• Insulin receptors and insulin action in the brain: review and clinical implications.

  2000cited by this paper
• Glucocorticoids and insulin resistance: old hormones, new targets.

  1999influential reference
• The Insulin Receptor Tyrosine Kinase Substrate p58/53 and the Insulin Receptor Are Components of CNS Synapses

  1999cited by this paper
• Insulin affects dopamine overflow in the nucleus accumbens and the striatum.

  1998cited by this paper
• Mineralocorticoid receptors in the central nervous system.

  1996cited by this paper
• Glutamate uptake into astrocytes stimulates aerobic glycolysis: a mechanism coupling neuronal activity to glucose utilization.

  1994influential reference
• Insulin gene expression and insulin synthesis in mammalian neuronal cells.

  1994cited by this paper
• Insulin receptor substrate-1 (IRS-1) distribution in the rat central nervous system

  1994cited by this paper
• Effect of insulin of glucose and glycogen metabolism and leucine incorporation into protein in cultured mouse astrocytes

  1992cited by this paper
• Refinement of the Kinetic Model of the 2-[14C]Deoxyglucose Method to Incorporate Effects of Intracellular Compartmentation in Brain

  1989influential reference
• Localization and Characterization of Insulin‐Like Growth Factor‐I Receptors in Rat Brain and Pituitary Gland Using in vitro Autoradiography and Computerized Densitometry * A Distinct Distribution from Insulin Receptors

  1989influential reference
• Regulation of rat brain/HepG2 glucose transporter gene expression by insulin and insulin-like growth factor-I in primary cultures of neuronal and glial cells.

  1989cited by this paper
• Local cerebral glucose utilization is increased in acutely adrenalectomized rats.

  1988cited by this paper
• Localization and characterization of insulin receptors in rat brain and pituitary gland using in vitro autoradiography and computerized densitometry.

  1987influential reference
• Insulin Is Released from Rat Brain Neuronal Cells in Culture

  1986cited by this paper
• Effect of L-DOPA on glucose oxidation and incorporation into glycogen in discrete brain regions of the rat.

  1985cited by this paper
• Insulin binds to specific receptors and stimulates 2-deoxy-D-glucose uptake in cultured glial cells from rat brain.

  1984cited by this paper
• Increased glucose metabolism during long-duration recurrent inhibition of hippocampal pyramidal cells

  1984cited by this paper
• Central nervous system insulin receptors in normal and diabetic rats.

  1979cited by this paper
• Central nervous system insulin receptors in normal and diabetic rats.

  1979cited by this paper
• Identification of insulin in rat brain.

  1978cited by this paper
• Serveur Académique Lausannois SERVAL serval.unil.ch

  year unknowncited by this paper

• Loss of brain energy metabolism control as a driver for memory impairment upon insulin resistance.

  2023cites this paper
• Multiplexed Membrane Signaling by Glucocorticoids.

  2022cites this paper
• Glucocorticoids, metabolism and brain activity.

  2021cites this paper
• Transient Gain of Function of Cannabinoid CB1 Receptors in the Control of Frontocortical Glucose Consumption in a Rat Model of Type-1 Diabetes.

  2020cites this paper
• Chronic insulinopenia/hyperglycemia decreases cannabinoid CB1 receptor density and impairs glucose uptake in the mouse forebrain.

  2019cites this paper
• El Sistema de Endocannabinoides como regulador de la lipogénesis y su posible modulación por la mangiferina

  2019influential citation
• Anandamide Effects in a Streptozotocin-Induced Alzheimer’s Disease-Like Sporadic Dementia in Rats

  2018cites this paper
• Novel mechanisms of glucocorticoid-induced insulin resistance in human adipose tissue

  2018cites this paper
• Brain endocannabinoid signaling exhibits remarkable complexity.

  2018cites this paper
• Endocannabinoids: Effectors of glucocorticoid signaling.

  2017influential citation
• Cannabis: A Treasure Trove or Pandora's Box?

  2017cites this paper
• Effects of tetrahydrocannabinol on glucose uptake in the rat brain

  2017cites this paper
• Role of cannabinoid receptor 1 in human adipose tissue for lipolysis regulation and insulin resistance

  2016cites this paper