Nerve growth factor-induced neuronal differentiation of PC12 pheochromocytoma cells: lack of inhibition by a tumor promoter.

No abstract is available for this paper.

• Publication year

  1982

• Venue

  Brain Research

• Publication date

  1982-09-09

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/0006-8993(82)91033-2PMID 7127107
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Variation with embryonic development and regional localization of specific [3H]phorbol 12,13-dibutyrate binding to brain.

  1981cited by this paper
• Tumor promoter modulation of epidermal growth factor‐ and nerve growth factor‐induced adhesion and growth factor binding of PC‐12 pheochromocytoma cells

  1980cited by this paper
• Characterization of specific binding of [3H]phorbol 12,13-dibutyrate and [3H]phorbol 12-myristate 13-acetate to mouse brain.

  1980cited by this paper
• Tumor promoters inhibit morphological differentiation in cultured mouse neuroblastoma cells.

  1978cited by this paper
• Nerve growth factor.

  1978cited by this paper
• Epidermal growth factor, like phorbol esters, induces plasminogen activator in HeLa cells

  1978cited by this paper
• Stimulation of DNA synthesis by tumour promoter and pure mitogenic factors

  1978cited by this paper
• Effect of tumor promoters on the response of cultured embryonic chick ganglia to nerve growth factor.

  1978cited by this paper
• Morphologic and cytochemical properties of a clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor.

  1978cited by this paper
• Evidence for RNA synthesis-dependent and -independent pathways in stimulation of neurite outgrowth by nerve growth factor.

  1978cited by this paper
• A quantitative bioassay for nerve growth factor (NGF) activity employing a clonal pheochromocytoma cell line.

  1977cited by this paper
• Characterization and isolation of proteolytically modified nerve growth factor.

  1976cited by this paper
• Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor.

  1976cited by this paper
• Mechanisms of lysosomal enzyme release from human polymorphonuclear leukocytes. Effects of phorbol myristate acetate

  1975cited by this paper
• Nerve growth factor.

  1975cited by this paper
• Phorbolesters--the irritants and cocarcinogens of Croton Tiglium L.

  1974cited by this paper
• Nerve growth factor.

  1968cited by this paper
• Reconstituted rattail collagen used as substrate for tissue cultures on coverslips in Maximow slides and roller tubes.

  1958cited by this paper

• Eerdun Wurile protects neuron and promotes neurite outgrowth through regulation of apoptotic gene expression in PC-12 cells

  2020cites this paper
• Image-derived models of cell organization changes during differentiation and drug treatments

  2019cites this paper
• Protein kinases: master regulators of neuritogenesis and therapeutic targets for axon regeneration

  2019cites this paper
• Image-derived Models of Cell Organization Changes During Differentiation of PC12 Cells

  2019cites this paper
• Systems Biology of Transcription Regulation

  2016cites this paper
• Boolean Modeling Reveals the Necessity of Transcriptional Regulation for Bistability in PC12 Cell Differentiation

  2016cites this paper
• Gene Interference with Morpholinos in a Gold Nanoparticle-Based Delivery Platform in Rat PC12 Cells.

  2015cites this paper
• Using Mouse Mammary Tumor Cells to Teach Core Biology Concepts: A Simple Lab Module.

  2015cites this paper
• The Extraction of Simple Relationships in Growth Factor-Specific Multiple-Input and Multiple-Output Systems in Cell-Fate Decisions by Backward Elimination PLS Regression

  2013cites this paper
• Latent process genes for cell differentiation are common decoders of neurite extension length

  2012cites this paper
• Induction of neurite outgrowth by α-phenyl-N-tert-butylnitrone through nitric oxide release and Ras-ERK pathway in PC12 cells

  2010cites this paper
• Timing-Dependent Actions of NGF Required for Cell Differentiation

  2010cites this paper
• PrPc activation induces neurite outgrowth and differentiation in PC12 cells: role for caveolin‐1 in the signal transduction pathway

  2009cites this paper
• Effect of Tremella fuciformis on the neurite outgrowth of PC12h cells and the improvement of memory in rats.

  2007cites this paper
• Nerve growth factor-induced differentiation of PC12 cells employs the PMA-insensitive protein kinase C-ζ isoform

  2007cites this paper
• Identification and Characterization of Compounds That Potentiate NT-3-Mediated Trk Receptor Activity

  2006influential citation
• Fundamental role of nitric oxide in neuritogenesis of PC12h cells

  2005cites this paper
• Pro-NGF isolated from the human brain affected by Alzheimer's disease induces neuronal apoptosis mediated by p75NTR.

  2005cites this paper
• In Vivo Evaluation of Pharmacologically Active Microcarriers Releasing Nerve Growth Factor and Conveying PC12 Cells

  2004cites this paper
• Activation of protein kinase C inhibits retrograde transport of neurotrophins in mice

  2003cites this paper
• Differential roles of ERK and JNK in early and late stages of neuritogenesis: a study in a novel PC12 model system

  2003cites this paper
• Inhibition by Wnt-1 or Wnt-3a of nerve growth factor-induced differentiation of PC12 cells is reversed by bisindolylmaleimide-I but not by several other PKC inhibitors

  2002cites this paper
• The Basic Region and Leucine Zipper Transcription Factor MafK Is a New Nerve Growth Factor-Responsive Immediate Early Gene That Regulates Neurite Outgrowth

  2002cites this paper
• Induction of Neurite Outgrowth in PC12 Cells by α-Phenyl-N-tert-butylnitron through Activation of Protein Kinase C and the Ras-Extracellular Signal-regulated Kinase Pathway*

  2001cites this paper
• Protein kinase C-epsilon plays a role in neurite outgrowth in response to epidermal growth factor and nerve growth factor in PC12 cells.

  1999cites this paper
• PKC activators (phorbol ester or bryostatin) stimulate outgrowth of NGF‐dependent neurites in a subline of PC12 cells

  1998cites this paper
• Mediation of NGF signaling by post-translational inhibition of HES-1, a basic helix-loop-helix repressor of neuronal differentiation.

  1997cites this paper
• Involvement of protein kinase C in nerve growth factor‐ and K‐252a‐stimulated calcium uptake into PC12 cells

  1997cites this paper
• Src, ras, and rac mediate the migratory response elicited by NGF and PMA in PC12 cells

  1996cites this paper
• Role of Protein Kinase C α in Nerve Growth Factor‐Induced Arachidonic Acid Release from PC12 Cells

  1996cites this paper
• Protein kinase- and staurosporine-dependent induction of neurite outgrowth and plasminogen activator activity in PC12 cells.

  1996cites this paper
• Selective Translocation ofProtein Kinase C-6 inPC12Cells during NerveGrowth Factor-induced Neuritogenesis

  1995cites this paper
• Selective translocation of protein kinase C-delta in PC12 cells during nerve growth factor-induced neuritogenesis.

  1995cites this paper
• Nerve growth factor-induced differentiation of PC12 cells employs the PMA-insensitive protein kinase C-zeta isoform.

  1994cites this paper
• Neurite Outgrowth Stimulated by the Tyrosine Kinase Inhibitor Herbimycin A Requires Activation of Tyrosine Kinases and Protein Kinase C

  1994cites this paper
• Protein Kinase Inhibitor H‐7 Differentially Affects Early and Delayed Nerve Growth Factor Responses in PC12 Cells

  1994cites this paper
• Differentiation of PC12 cells in response to a cAMP analogue is accompanied by sustained activation of mitogen‐activated protein kinase

  1994cites this paper
• Growth factors protect PC12 cells against ischemia by a mechanism that is independent of PKA, PKC, and protein synthesis

  1993cites this paper
• Increased Neurite Outgrowth Induced by Inhibition of Protein Tyrosine Kinase Activity in PC12 Pheochromocytoma Cells

  1993cites this paper
• Protein kinase C isozymes that mediate enhancement of neurite outgrowth by ethanol and phorbol esters in PC12 cells.

  1993cites this paper
• 5 – Nerve Growth Factor and Related Substances: Structure and Mechanism of Action

  1993cites this paper
• The 38-amino acid form of pituitary adenylate cyclase-activating polypeptide stimulates dual signaling cascades in PC12 cells and promotes neurite outgrowth.

  1992cites this paper
• Testing the in vivo role of protein kinase C and c-fos in neurite outgrowth by microinjection of antibodies into PC12 cells.

  1992cites this paper
• Phosphorylation of translation initiation factor eIF-4E is induced in a ras-dependent manner during nerve growth factor-mediated PC12 cell differentiation

  1992cites this paper
• Differential induction of primary-response (TIS) genes in PC12 pheochromocytoma cells and the unresponsive variant PC12nnr5.

  1991cites this paper
• Chapter 5: Expression of the growth- and plasticity-associated

  1991cites this paper
• Chronic exposure to an activator of protein kinase C mimics early effects of NGF in chromaffin cells.

  1991cites this paper
• Effect of nerve growth factor and fibroblast growth factor on SCG10 and c-fos expression and neurite outgrowth in protein kinase C-depleted PC12 cells.

  1990cites this paper
• Potentiation of oncogenic N‐ras‐induced neurite outgrowth and ornithine decarboxylase activity by phorbol dibutyrate and protein kinase inhibitor H‐8

  1990cites this paper
• Effect of protein kinase modulators on the induction of morphological differentiation of pheochromocytoma PC12 cells by nerve and fibroblast growth factors

  1990cites this paper
• Role of the cAMP‐dependent protein kinase and protein kinase C in regulating the morphological differentiation of PC12 cells

  1990cites this paper
• Nerve growth factor regulates gene expression by several distinct mechanisms

  1989cites this paper
• The lack of a role for protein kinase C in neurite extension and in the induction of ornithine decarboxylase by nerve growth factor in PC12 cells.

  1989cites this paper
• Suppression of nerve growth factor-directed neurite outgrowth in PC12 cells by sphingosine, an inhibitor of protein kinase C.

  1988cites this paper
• Protein Kinase C and its Role in Cell Growth

  1987cites this paper
• Neuritic growth from a new subline of PC12 pheochromocytoma cells: Cyclic AMP mimics the action of nerve growth factor

  1987cites this paper
• Cholinergic neurons of fetal rat telencephalon in aggregating cell culture respond to NGF as well as to protein kinase C-activating tumor promoters.

  1986cites this paper
• Nerve growth factor induces mast cell degranulation without changing intracellular calcium levels

  1986cites this paper
• Phorbol diesters and cellular differentiation.

  1984cites this paper
• PC12 Pheochromocytoma Cultures in Neurobiological Research

  1982cites this paper