Fatal outbreak of an emerging clone of extensively drug-resistant Acinetobacter baumannii with enhanced virulence.

No abstract is available for this paper.

• Publication year

  2015

• Venue

  Clinical Infectious Diseases

• Publication date

  2015-03-29

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1093/cid/civ225PMID 25824815
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Host fate is rapidly determined by innate effector-microbial interactions during Acinetobacter baumannii bacteremia.

  2014cited by this paper
• The antimicrobial resistance monitoring and research (ARMoR) program: the US Department of Defense response to escalating antimicrobial resistance.

  2014cited by this paper
• AB5075, a Highly Virulent Isolate of Acinetobacter baumannii, as a Model Strain for the Evaluation of Pathogenesis and Antimicrobial Treatments

  2014cited by this paper
• The structure of the polysaccharide isolated from Acinetobacter baumannii strain LAC-4.

  2014cited by this paper
• Amplification of Aminoglycoside Resistance Gene aphA1 in Acinetobacter baumannii Results in Tobramycin Therapy Failure

  2014cited by this paper
• Infectious diseases specialty intervention is associated with decreased mortality and lower healthcare costs.

  2014cited by this paper
• Genomic and Functional Analysis of the Type VI Secretion System in Acinetobacter

  2013cited by this paper
• Acinetobacter baumannii: human infections, factors contributing to pathogenesis and animal models.

  2013cited by this paper
• Acinetobacter baumannii Utilizes a Type VI Secretion System for Bacterial Competition

  2013cited by this paper
• A Mouse Model of Acinetobacter baumannii-Associated Pneumonia Using a Clinically Isolated Hypervirulent Strain

  2013cited by this paper
• Diversity in the Major Polysaccharide Antigen of Acinetobacter Baumannii Assessed by DNA Sequencing, and Development of a Molecular Serotyping Scheme

  2013cited by this paper
• Emergence of colistin-resistance in extremely drug-resistant Acinetobacter baumannii containing a novel pmrCAB operon during colistin therapy of wound infections.

  2013cited by this paper
• Deadly syringes: type VI secretion system activities in pathogenicity and interbacterial competition.

  2013cited by this paper
• Complete genome sequence of Acinetobacter baumannii MDR-TJ and insights into its mechanism of antibiotic resistance.

  2012cited by this paper
• Detection of Bacterial 16S rRNA and Identification of Four Clinically Important Bacteria by Real-Time PCR

  2012cited by this paper
• Inhibition of LpxC Protects Mice from Resistant Acinetobacter baumannii by Modulating Inflammation and Enhancing Phagocytosis

  2012cited by this paper
• Differences in Acinetobacter baumannii Strains and Host Innate Immune Response Determine Morbidity and Mortality in Experimental Pneumonia

  2012cited by this paper
• Dosing Regimen Matters: the Importance of Early Intervention and Rapid Attainment of the Pharmacokinetic/Pharmacodynamic Target

  2012cited by this paper
• Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: an international expert proposal for interim standard definitions for acquired resistance.

  2012cited by this paper
• Diabetic murine models for Acinetobacter baumannii infection.

  2012cited by this paper
• Recurrent Bacteremia Caused by the Acinetobacter calcoaceticus-Acinetobacter baumannii Complex

  2012cited by this paper
• Influence of genospecies of Acinetobacter baumannii complex on clinical outcomes of patients with acinetobacter bacteremia.

  2011cited by this paper
• Growth of Acinetobacter baumannii in Pellicle Enhanced the Expression of Potential Virulence Factors

  2011cited by this paper
• Updating and validating the Charlson comorbidity index and score for risk adjustment in hospital discharge abstracts using data from 6 countries.

  2011cited by this paper
• VFDB 2012 update: toward the genetic diversity and molecular evolution of bacterial virulence factors

  2011cited by this paper
• Genome-wide recombination drives diversification of epidemic strains of Acinetobacter baumannii

  2011cited by this paper
• Clonal Diversity of Nosocomial Epidemic Acinetobacter baumannii Strains Isolated in Spain

  2010cited by this paper
• Diversity and Clinical Impact of Acinetobacter baumannii Colonization and Infection at a Military Medical Center

  2010cited by this paper
• Inflammatory Biomarkers in Combat Wound Healing

  2009cited by this paper
• Bad bugs, no drugs: no ESKAPE! An update from the Infectious Diseases Society of America.

  2009cited by this paper
• SCORING SYSTEMS FOR PREDICTION OF MORTALITY IN PATIENTS WITH INTENSIVE CARE UNIT-ACQUIRED SEPSIS: A COMPARISON OF THE PITT BACTEREMIA SCORE AND THE ACUTE PHYSIOLOGY AND CHRONIC HEALTH EVALUATION II SCORING SYSTEMS

  2009cited by this paper
• Phenotypic and Molecular Characterization of Acinetobacter baumannii Clinical Isolates from Nosocomial Outbreaks in Los Angeles County, California

  2008cited by this paper
• Multidrug-resistant Acinetobacter Infection Mortality Rate and Length of Hospitalization

  2007cited by this paper
• Clinical and Economic Impact of Multidrug Resistance in Nosocomial Acinetobacter baumannii Bacteremia

  2007cited by this paper
• Identification of Acinetobacter Species and Genotyping of Acinetobacter baumannii by Multilocus PCR and Mass Spectrometry

  2006cited by this paper
• Attributable mortality of Acinetobacter baumannii infection among critically ill patients.

  2006cited by this paper
• Reply to Falagas et al

  2006cited by this paper
• Clinical impact of pneumonia caused by Acinetobacter baumannii in intubated patients: A matched cohort study*

  2003cited by this paper
• Nosocomial bacteremia involving Acinetobacter baumannii in critically ill patients: a matched cohort study

  2003cited by this paper
• Use of a new mouse model of Acinetobacter baumannii pneumonia to evaluate the postantibiotic effect of imipenem

  1997cited by this paper
• A new Simplified Acute Physiology Score (SAPS II) based on a European/North American multicenter study

  1993cited by this paper
• A new Simplified Acute Physiology Score (SAPS II) based on a European/North American multicenter study.

  1993cited by this paper

• Secondary bacterial infections of Carbapenem-Resistant Acinetobacter baumannii in patients with COVID-19 admitted to Chinese ICUs

  2025cites this paper
• Emerging virulent clones of community-onset Acinetobacter baumannii in Taiwan

  2025cites this paper
• High-quality Acinetobacter genomes recovered from combat wounds via metagenomic sequencing resemble cultured isolate genomes

  2025cites this paper
• Structure of the K49 capsular polysaccharide produced by the Acinetobacter baumannii ST10 carriage isolate, NL6.

  2025cites this paper
• Virulence factors are preserved within carbapenem-resistant Acinetobacter baumannii clades

  2025cites this paper
• Genomic insights into biofilm-associated virulence in extensively drug-resistant Acinetobacter baumannii

  2025cites this paper
• Contribution of RND superfamily multidrug efflux pumps AdeABC, AdeFGH, and AdeIJK to antimicrobial resistance and virulence factors in multidrug-resistant Acinetobacter baumannii AYE

  2025cites this paper
• Risk factors and genetic characteristics of the carriage of hypervirulent and carbapenem-resistant Acinetobacter baumannii among pregnant women

  2024cites this paper
• Infection Prevention and Control Strategies According to the Type of Multidrug-Resistant Bacteria and Candida auris in Intensive Care Units: A Pragmatic Resume including Pathogens R0 and a Cost-Effectiveness Analysis

  2024cites this paper
• Comparison of Hypervirulent and Non-Hypervirulent Carbapenem-Resistant Acinetobacter baumannii Isolated from Bloodstream Infections: Mortality, Potential Virulence Factors, and Combination Therapy In Vitro

  2024cites this paper
• Tracing Acinetobacter baumannii’s Journey from Hospitals to Aquatic Ecosystems

  2024cites this paper
• A series of vectors for inducible gene expression in multidrug-resistant Acinetobacter baumannii

  2024cites this paper
• Characteristics of the Genetic Spread of Carbapenem-Resistant Acinetobacter baumannii in a Tertiary Greek Hospital

  2024cites this paper
• First detection of a cefiderocol-resistant and extensively drug-resistant Acinetobacter baumannii clinical isolate in Bulgaria.

  2024cites this paper
• Deciphering the virulence factors, regulation, and immune response to Acinetobacter baumannii infection

  2023cites this paper
• Molecular and virulence characteristics of carbapenem-resistant Acinetobacter baumannii isolates: a prospective cohort study

  2023cites this paper
• Multidrug-Resistant and Extensively Drug-Resistant Acinetobacter baumannii Causing Nosocomial Meningitis in the Neurological Intensive Care Unit

  2023cites this paper
• Effect of Photodynamic Therapy on Multidrug-resistant Acinetobacter baumannii: A scoping review.

  2023cites this paper
• In Vitro Activity of Cefiderocol against a Global Collection of Carbapenem-Resistant Acinetobacter baumannii Isolates

  2023cites this paper
• An Explorative Review on Advanced Approaches to Overcome Bacterial Resistance by Curbing Bacterial Biofilm Formation

  2023cites this paper
• Infections Due to Acinetobacter baumannii-calcoaceticus Complex: Escalation of Antimicrobial Resistance and Evolving Treatment Options.

  2022cites this paper
• Acinetobacter baumannii from the one health perspective in Nigeria: A systematic review of literature in the last decade (2011-2021)

  2022cites this paper
• Correlation analysis between drug resistance and virulence genes of carbapenem-resistant Acinetobacter baumannii In Western Guilin

  2022cites this paper
• Risk factors for early mortality in patients with carbapenem-resistant Acinetobacter baumannii bacteremia.

  2022cites this paper
• Incidence of an Intracellular Multiplication Niche among Acinetobacter baumannii Clinical Isolates

  2022cites this paper
• Acinetobacter stercoris sp. nov. isolated from output source of a mesophilic german biogas plant with anaerobic operating conditions

  2021cites this paper
• Clinical Efficacy and Nephrotoxicity of the Loading Dose Colistin for the Treatment of Carbapenem-Resistant Acinetobacter baumannii in Critically Ill Patients

  2021cites this paper
• Association of capsular polysaccharide locus 2 with prognosis of Acinetobacter baumannii bacteraemia

  2021cites this paper
• Adverse clinical outcomes associated with carbapenem-resistant Acinetobacter (CRA) infections: a systematic review and meta-analysis

  2021cites this paper
• A five-component infection control bundle to permanently eliminate a carbapenem-resistant Acinetobacter baumannii spreading in an intensive care unit

  2021cites this paper
• Acinetobacter defence mechanisms against biological aggressors and their use as alternative therapeutic applications

  2021cites this paper
• Does Enhanced Environmental Cleaning Reduce Carbapenem-Resistant Acinetobacter baumannii Colonization in the Intensive Care Unit?

  2021cites this paper
• Incidence of an intracellular multiplication niche amongst Acinetobacter baumannii clinical isolates

  2021cites this paper
• Genomic surveillance, characterization and intervention of a polymicrobial multidrug-resistant outbreak in critical care

  2021cites this paper
• What is the optimal antibiotic treatment strategy for carbapenem-resistant Acinetobacter baumannii (CRAB)? A multicenter study in Korea.

  2021cites this paper
• Novel Subclone of Carbapenem-Resistant Klebsiella pneumoniae Sequence Type 11 with Enhanced Virulence and Transmissibility, China

  2020cites this paper
• Using comparative genomics to understand molecular features of carbapenem-resistant Acinetobacter baumannii from South Korea causing invasive infections and their clinical implications

  2020cites this paper
• Spatio-Temporal Distribution of Acinetobacter baumannii in Germany—A Comprehensive Systematic Review of Studies on Resistance Development in Humans (2000–2018)

  2020cites this paper
• Acquisition of plasmids conferring carbapenem and aminoglycoside resistance and loss of surface-exposed macromolecule structures as strategies for the adaptation of Acinetobacter baumannii CC104O/CC15P strains to the clinical setting

  2020cites this paper
• Acinetobacter baumannii NCIMB8209: a Rare Environmental Strain Displaying Extensive Insertion Sequence-Mediated Genome Remodeling Resulting in the Loss of Exposed Cell Structures and Defensive Mechanisms

  2020cites this paper
• In vitro activity of sulbactam/durlobactam against global isolates of carbapenem-resistant Acinetobacter baumannii.

  2020cites this paper
• Genomic characterization of the virulence-associated pyomelanin biosynthetic pathway in pigment-producer strains from the pandemic Acinetobacter baumannii IC-5

  2020cites this paper
• Genomic surveillance, characterisation and intervention of a carbapenem-resistant Acinetobacter baumannii outbreak in critical care

  2020cites this paper
• Characterization of carbapenem-resistant hypervirulent Acinetobacter baumannii strains isolated from hospitalized patients in the mid-south region of China

  2020cites this paper
• Pyomelanin biosynthetic pathway in pigment-producer strains from the pandemic Acinetobacter baumannii IC-5

  2020cites this paper
• Rapid Identification of KL49 Acinetobacter baumannii Associated with Clinical Mortality

  2020cites this paper
• Transmission of Hypervirulent Acinetobacter baumannii Between General and Intensive Care Unit

  2020cites this paper
• Protein Export and Secretion Among Bacterial Pathogens

  2020cites this paper
• Genomic epidemiology of severe community-onset Acinetobacter baumannii infection

  2019influential citation
• Skin and Soft Tissue Models for Acinetobacter baumannii Infection.

  2019cites this paper
• A Porcine Wound Model of Acinetobacter baumannii Infection

  2019cites this paper
• A lethal pneumonia model of Acinetobacter baumannii: an investigation in immunocompetent mice.

  2019cites this paper
• Wza gene knockout decreases Acinetobacter baumannii virulence and affects Wzy-dependent capsular polysaccharide synthesis

  2019cites this paper
• The Slow-Motion Catastrophe of Antimicrobial Resistance and Practical Interventions for All Prescribers.

  2019cites this paper
• Bioinformatic Analysis of the Type VI Secretion System and Its Potential Toxins in the Acinetobacter Genus

  2019influential citation
• Evolution of Acinetobacter baumannii infections and antimicrobial resistance. A review

  2019cites this paper
• Aminoglycoside-modifying enzyme and 16S ribosomal RNA methyltransferase genes among a global collection of Gram-negative isolates.

  2019cites this paper
• In-vitro activity of the novel fluorocycline TP-6076 against carbapenem-resistant Acinetobacter baumannii.

  2019cites this paper
• Microbiological and clinical characteristics of Acinetobacter baumannii bacteremia: Implications of sequence type for prognosis.

  2019cites this paper
• Moderate Genetic Diversity with Extensive Antimicrobial Resistance Among Multidrug-Resistant Acinetobacter baumannii in a Referral Hospital in Northeast Iran

  2018cites this paper
• Comparative analysis of the pathogenicity between multidrug-resistant Acinetobacter baumannii clinical isolates: isolation of highly pathogenic multidrug-resistant A. baumannii and experimental therapeutics with fourth-generation cephalosporin cefozopran

  2018cites this paper
• Natural prognosis of carbapenem-resistant Acinetobacter baumannii bacteremia in patients who did not receive appropriate antibiotic treatment

  2018cites this paper
• Risk factors for mortality in ICU patients with Acinetobacter baumannii ventilator-associated pneumonia: impact of bacterial cytotoxicity.

  2018cites this paper
• The Fight Against Antimicrobial Resistance Is Confounded by a Global Increase in Antibiotic Usage.

  2018cites this paper
• Simultaneous emergence and rapid spread of three OXA-23 producing Acinetobacter baumannii ST208 strains in intensive care units confirmed by whole genome sequencing.

  2018cites this paper
• Infecciones por bacilos Gram negativos no fermentadores: Pseudomonas aeruginosa, Acinetobacter spp. y Stenotrophomonas maltophilia

  2018cites this paper
• In-vitro activity of the novel fluorocycline eravacycline against carbapenem non-susceptible Acinetobacter baumannii.

  2018cites this paper
• Intensive Patient Treatment

  2018cites this paper
• Evolution Underway in Prokaryotes

  2018cites this paper
• A Rapidly Fatal Infection With Haemophilus influenzae Serotype E Harboring blaROB-1: The Dilemma of Safe De-escalation in the Setting of Potential Extended-Spectrum β-Lactamase Production

  2018cites this paper
• An intervention to control an ICU outbreak of carbapenem-resistant Acinetobacter baumannii: long-term impact for the ICU and hospital

  2018cites this paper
• An Emerging Clone (ST457) of Acinetobacter baumannii Clonal Complex 92 With Enhanced Virulence and Increasing Endemicity in South China.

  2018cites this paper
• Mouse model of colonization of the digestive tract with Acinetobacter baumannii and subsequent pneumonia.

  2017cites this paper
• Biology of Acinetobacter baumannii: Pathogenesis, Antibiotic Resistance Mechanisms, and Prospective Treatment Options

  2017cites this paper
• Targeting the Type II Secretion System: Development, Optimization, and Validation of a High-Throughput Screen for the Identification of Small Molecule Inhibitors

  2017cites this paper
• Prevalence of Acinetobacter baumannii strains expressing the Type 6 secretion system in patients with bacteremia

  2017cites this paper
• Infections Due to Acinetobacter baumannii in the ICU: Treatment Options

  2017cites this paper
• Exposure to dairy manure leads to greater antibiotic resistance and increased mass-specific respiration in soil microbial communities

  2017cites this paper
• Interplay Between Antibiotic Resistance and Virulence During Disease Promoted by Multidrug-Resistant Bacteria

  2017cites this paper
• Towards the complete proteinaceous regulome of Acinetobacter baumannii

  2017cites this paper
• Main conclusions and options for response

  2017cites this paper
• In vivo development of tigecycline resistance in Klebsiella pneumoniae owing to deletion of the ramR ribosomal binding site.

  2017cites this paper
• Pharmacodynamics of minocycline against Acinetobacter baumannii studied in a pharmacokinetic model of infection.

  2017cites this paper
• Evolution of Acinetobacter baumannii In Vivo: International Clone II, More Resistance to Ceftazidime, Mutation in ptk

  2017cites this paper
• Estudio de la trascendencia clínica de la colonización por Acinetobacter baumannii en una Unidad de Cuidados Intensivos (UCI) médica. Utilidad de los programas de cribado semanal y medidas de vigilancia y control de la infección nosocomial

  2017cites this paper
• The Type II Secretion System in Acinetobacter baumannii: Its Role in Pathogenesis and Translational Implications

  2017cites this paper
• Analysis of drug resistance in 1,861 strains of Acinetobacter baumannii.

  2016cites this paper
• Clinical and Pathophysiological Overview of Acinetobacter Infections: a Century of Challenges

  2016cites this paper
• Structural Diversity in the Type IV Pili of Multidrug-resistant Acinetobacter*

  2016cites this paper
• A glimpse into evolution and dissemination of multidrug-resistant Acinetobacter baumannii isolates in East Asia: a comparative genomics study

  2016cites this paper
• Terms of use : Click here Costs and Mortality Associated With Multidrug-Resistant Healthcare-Associated Acinetobacter Infections

  2016cites this paper
• Immunoprotective potential of in silico predicted Acinetobacter baumannii outer membrane nuclease, NucAb.

  2016cites this paper
• Emergence of antimicrobial resistance among Acinetobacter species: a global threat

  2016cites this paper
• Costs and Mortality Associated With Multidrug-Resistant Healthcare-Associated Acinetobacter Infections

  2016cites this paper
• The First Cut Is the Deepest

  2016cites this paper
• Antimicrobial Resistance and Drug Efflux Pumps in Acinetobacter

  2016cites this paper
• Editorial commentary: the new Acinetobacter equation: hypervirulence plus antibiotic resistance equals big trouble.

  2015influential citation
• Differential Role of the T6SS in Acinetobacter baumannii Virulence

  2015cites this paper
• Acinetobater baumannii: A Superbug

  2015cites this paper
• Next-Generation Sequencing and Comparative Analysis of Sequential Outbreaks Caused by Multidrug-Resistant Acinetobacter baumannii at a Large Academic Burn Center

  2015cites this paper