A common missense variant in the neuregulin 1 gene is associated with both schizophrenia and sudden cardiac death.

No abstract is available for this paper.

• Publication year

  2013

• Venue

  Heart Rhythm

• Publication date

  2013-07-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1016/j.hrthm.2013.03.020PMID 23524320PMCID PMC3692570
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Epilepsy Is a Risk Factor for Sudden Cardiac Arrest in the General Population

  2012cited by this paper
• Genetic associations between neuregulin-1 SNPs and neurocognitive function in multigenerational, multiplex schizophrenia families

  2012cited by this paper
• Neuregulin 1 regulates excitability of fast-spiking neurons through Kv1.1 and acts in epilepsy

  2011cited by this paper
• Sudden deaths in psychiatric patients.

  2011cited by this paper
• Identification of a Sudden Cardiac Death Susceptibility Locus at 2q24.2 through Genome-Wide Association in European Ancestry Individuals

  2011cited by this paper
• Genome-wide association study identifies a susceptibility locus at 21q21 for ventricular fibrillation in acute myocardial infarction

  2010cited by this paper
• Common Variants in Cardiac Ion Channel Genes Are Associated With Sudden Cardiac Death

  2010cited by this paper
• Etiology of sudden death in the community: results of anatomical, metabolic, and genetic evaluation.

  2010cited by this paper
• Gene variants associated with schizophrenia in a Norwegian genome-wide study are replicated in a large European cohort.

  2010cited by this paper
• CACNA1C (rs1006737) is associated with schizophrenia

  2010cited by this paper
• Genome-Wide Association Study Identifies GPC5 as a Novel Genetic Locus Protective against Sudden Cardiac Arrest

  2010cited by this paper
• Sudden Cardiac Death Prediction and Prevention: Report From a National Heart, Lung, and Blood Institute and Heart Rhythm Society Workshop

  2010cited by this paper
• Biological validation of increased schizophrenia risk with NRG1, ERBB4, and AKT1 epistasis via functional neuroimaging in healthy controls.

  2010cited by this paper
• Three-cohort targeted gene screening reveals a non-synonymous TRKA polymorphism associated with schizophrenia.

  2009cited by this paper
• DISC1 splice variants are upregulated in schizophrenia and associated with risk polymorphisms

  2009cited by this paper
• Determinants of Prolonged QT Interval and Their Contribution to Sudden Death Risk in Coronary Artery Disease: The Oregon Sudden Unexpected Death Study

  2009cited by this paper
• Identification of a possible pathogenic link between congenital long QT syndrome and epilepsy

  2009cited by this paper
• Atypical antipsychotic drugs and the risk of sudden cardiac death.

  2009cited by this paper
• Epidemiology of sudden cardiac death: clinical and research implications.

  2008cited by this paper
• KCNQ2 and KCNQ3 mutations contribute to different idiopathic epilepsy syndromes

  2008cited by this paper
• PLINK: a tool set for whole-genome association and population-based linkage analyses.

  2007cited by this paper
• Population-based analysis of sudden cardiac death with and without left ventricular systolic dysfunction: two-year findings from the Oregon Sudden Unexpected Death Study.

  2006cited by this paper
• Family History and the Risk of Sudden Cardiac Death as a Manifestation of an Acute Coronary Event

  2006cited by this paper
• Supportive evidence for an allelic association of the human KCNJ10 potassium channel gene with idiopathic generalized epilepsy.

  2005cited by this paper
• Prospective Study of Sudden Cardiac Death Among Women in the United States

  2003cited by this paper
• Neuregulin 1 and susceptibility to schizophrenia.

  2002cited by this paper
• Sudden death and myocardial infarction in first degree relatives as predictors of primary cardiac arrest.

  2002cited by this paper
• Predictive Identification of Exonic Splicing Enhancers in Human Genes

  2002cited by this paper
• Predicting sudden death in the population: the Paris Prospective Study I.

  1999cited by this paper
• Sudden death in psychiatric patients

  1998cited by this paper
• Release of the Neuregulin Functional Polypeptide Requires Its Cytoplasmic Tail*

  1998cited by this paper
• Aberrant neural and cardiac development in mice lacking the ErbB4 neuregulin receptor

  1995cited by this paper
• Multiple essential functions of neuregulin in development

  1995cited by this paper
• [Sudden death in psychiatric patients].

  1990cited by this paper
• Meta-analysis of controlled clinical trials.

  1989cited by this paper
• Clinical Classification of Cardiac Deaths

  1982cited by this paper
• Predictive Identification of Exonic Splicing Enhancers in Human Genes

  year unknowncited by this paper

• A Study of Sudden Cardiac Death in Schizophrenia.

  2025cites this paper
• Sudden cardiac death in young adults and the role of antipsychotic drugs: a multicenter autopsy study.

  2025cites this paper
• Sudden Cardiac Death in People With Schizophrenia: Higher Risk, Poorer Resuscitation Profiles, and Differing Pathologies.

  2023cites this paper
• Sudden Cardiac Death in Schizophrenia During Hospitalization: An Autopsy-Based Study

  2022cites this paper
• Sudden cardiac arrest in patients with schizophrenia: A population-based study of resuscitation outcomes and pre-existing cardiovascular disease

  2022cites this paper
• Genetic investigations of 100 inherited cardiac disease-related genes in deceased individuals with schizophrenia

  2021cites this paper
• Witnessed and unwitnessed sudden cardiac death: a nationwide study of persons aged 1-35 years.

  2021cites this paper
• Sudden Cardiac Death in Schizophrenia: A Review.

  2020cites this paper
• A systematic review of single nucleotide polymorphisms in sudden cardiac death

  2020cites this paper
• [Electrocardiographic and hemodynamic profile of patients with psychotic disorder].

  2019cites this paper
• Pretreatment with neuregulin-1 improves cardiac electrophysiological properties in a rat model of myocardial infarction

  2019cites this paper
• Usefulness of Single Nucleotide Polymorphisms as Predictors of Sudden Cardiac Death.

  2019cites this paper
• Causes of Sudden Unexpected Death in Schizophrenia Patients: A Forensic Autopsy Population Study.

  2019cites this paper
• A critical review of zebrafish schizophrenia models: time for validation?

  2019cites this paper
• Sudden death in schizophrenia

  2018cites this paper
• Assessing Nurses' Demographic Cardiovascular Risk Factors and Pharmacogenetic Testing Knowledge and Acceptance

  2017cites this paper
• A Common Variant in SCN5A and the Risk of Ventricular Fibrillation Caused by First ST-Segment Elevation Myocardial Infarction

  2017cites this paper
• Syddansk Universitet A Common Variant in SCN 5 A and the Risk of Ventricular Fibrillation Caused by First ST-Segment Elevation Myocardial Infarction

  2017cites this paper
• Therapeutic Potential of Neuregulin in Cardiovascular System: Can we Ignore the Effects of Neuregulin on Electrophysiology?

  2016cites this paper
• Effects of prolonged antipsychotic administration on neuregulin-1/ErbB signaling in rat prefrontal cortex and myocardium: implications for the therapeutic action and cardiac adverse effect.

  2016cites this paper
• ErbB4 Gene Polymorphism Is Associated With the Risk and Prognosis of Congestive Heart Failure in a Northern Han Chinese Population.

  2016cites this paper
• Genetic variations involved in sudden cardiac death and their associations and interactions

  2016cites this paper
• Clinical Investigation ErbB4 Gene Polymorphism Is Associated With the Risk and Prognosis of Congestive Heart Failure in a Northern Han Chinese Population

  2016cites this paper
• A specified therapeutic window for neuregulin-1 to regenerate neonatal heart muscle.

  2015cites this paper
• Genetic markers of repolarization and arrhythmic events after acute coronary syndromes.

  2015cites this paper
• The Roles of Neuregulin-1 in Cardiac Development, Homeostasis, and Disease

  2015cites this paper
• Etiology of cardiovascular disease in patients with schizophrenia: current perspectives

  2015cites this paper
• PHYSICAL HEALTH CHECKS IN SERIOUS MENTAL ILLNESS: A PROGRAMME OF RESEARCH IN SECONDARY CARE

  2015cites this paper
• Cumulative effects of common genetic variants on risk of sudden cardiac death

  2015cites this paper
• Neuregulin-1/erbB activities with focus on the susceptibility of the heart to anthracyclines.

  2014cites this paper
• Brugada Syndrome ECG Is Highly Prevalent in Schizophrenia

  2014cites this paper
• Genetic Variants and Risk in Sudden Cardiac Death Syndromes

  2014cites this paper
• The role of the Neuregulin-1/Erbb signaling pathway in cardiac morphogenesis and remodeling

  2014cites this paper
• Neuregulin as a Heart Failure Therapy and Mediator of Reverse Remodeling

  2014cites this paper
• Genetics of sudden cardiac death caused by ventricular arrhythmias

  2014cites this paper
• QT Is Longer in Drug-Free Patients with Schizophrenia Compared with Age-Matched Healthy Subjects

  2014cites this paper
• Postmortem analysis of cardiovascular deaths in schizophrenia: a 10-year review.

  2013cites this paper
• Heart, brain, and the risk of sudden death.

  2013cites this paper