Kinetics of arsenic methylation by freshly isolated B6C3F1 mouse hepatocytes.

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Chemico-Biological Interactions

• Publication date

  2006-06-10

• Fields of study

  Medicine, Chemistry, Environmental Science

• Identifiers
  DOI 10.1016/J.CBI.2006.04.001PMID 16725132
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Arsenic toxicology: five questions.

  2006cited by this paper
• The glycolytic enzyme glyceraldehyde-3-phosphate dehydrogenase works as an arsenate reductase in human red blood cells and rat liver cytosol.

  2005cited by this paper
• A new metabolic pathway of arsenite: arsenic–glutathione complexes are substrates for human arsenic methyltransferase Cyt19

  2005cited by this paper
• Arsenic (+3 oxidation state) methyltransferase and the inorganic arsenic methylation phenotype.

  2005cited by this paper
• Comparison of Tissue Dosimetry in the Mouse Following Chronic Exposure to Arsenic Compounds

  2005cited by this paper
• A review of the enzymology of arsenic metabolism and a new potential role of hydrogen peroxide in the detoxication of the trivalent arsenic species.

  2004cited by this paper
• Interindividual variation in the metabolism of arsenic in cultured primary human hepatocytes.

  2004cited by this paper
• Physiologically Based Pharmacokinetic Modeling of Arsenic in the Mouse

  2004cited by this paper
• Polymorphisms in the human monomethylarsonic acid (MMA V) reductase/hGSTO1 gene and changes in urinary arsenic profiles.

  2003cited by this paper
• Induction of oxidative DNA damage by arsenite and its trivalent and pentavalent methylated metabolites in cultured human cells and isolated DNA.

  2003cited by this paper
• Dose-dependent biotransformation of arsenite in rats--not S-adenosylmethionine depletion impairs arsenic methylation at high dose.

  2003cited by this paper
• A NovelS-Adenosyl-l-methionine:Arsenic(III) Methyltransferase from Rat Liver Cytosol*

  2002cited by this paper
• S‐Adenosylmethionine: a control switch that regulates liver function

  2002cited by this paper
• Pharmacokinetic Modeling of Arsenite Uptake and Metabolism in Hepatocytes—Mechanistic Insights and Implications for Further Experiments

  2002cited by this paper
• Arsenite transport by mammalian aquaglyceroporins AQP7 and AQP9

  2002cited by this paper
• Human monomethylarsonic acid (MMA(V)) reductase is a member of the glutathione-S-transferase superfamily.

  2001cited by this paper
• Effect of phosphate transporter and methylation inhibitor drugs on the disposition of arsenate and arsenite in rats.

  2001cited by this paper
• The cellular metabolism and systemic toxicity of arsenic.

  2001cited by this paper
• S‐Adenosylmethionine regulates MAT1A and MAT2A gene expression in cultured rat hepatocytes: a new role for S‐adenosylmethionine in the maintenance of the differentiated status of the liver

  2000cited by this paper
• Comparative toxicity of trivalent and pentavalent inorganic and methylated arsenicals in rat and human cells

  2000cited by this paper
• Enzymatic methylation of arsenic compounds. VII. Monomethylarsonous acid (MMAIII) is the substrate for MMA methyltransferase of rabbit liver and human hepatocytes.

  1999cited by this paper
• Metabolism of arsenic in primary cultures of human and rat hepatocytes.

  1999cited by this paper
• Arsenite uptake and metabolism by rat hepatocyte primary cultures in comparison with kidney- and hepatocyte-derived rat cell lines.

  1999cited by this paper
• In vivo regulation by glutathione of methionine adenosyltransferase S-nitrosylation in rat liver.

  1999cited by this paper
• Enzymatic reduction of arsenic compounds in mammalian systems: the rate-limiting enzyme of rabbit liver arsenic biotransformation is MMA(V) reductase.

  1999cited by this paper
• Arsenic : exposure and health effects

  1997cited by this paper
• Extrapolation of in vitro enzyme induction data to humans in vivo.

  1997cited by this paper
• In vitro methylation of inorganic arsenic in mouse intestinal cecum.

  1997cited by this paper
• Mono- and dimethylation of arsenic in rat liver cytosol in vitro.

  1996cited by this paper
• Cellular uptake of trivalent arsenite and pentavalent arsenate in KB cells cultured in phosphate-free medium.

  1996cited by this paper
• Prediction of furan pharmacokinetics from hepatocyte studies: comparison of bioactivation and hepatic dosimetry in rats, mice, and humans.

  1996cited by this paper
• Enzymatic methylation of arsenic compounds: assay, partial purification, and properties of arsenite methyltransferase and monomethylarsonic acid methyltransferase of rabbit liver.

  1995cited by this paper
• Utility of in vitro drug metabolism data in predicting in vivo metabolic clearance.

  1994cited by this paper
• Kinetic analysis of furan biotransformation by F-344 rats in vivo and in vitro.

  1993cited by this paper
• Phospholipid methylation in brain membrane preparations: kinetic mechanism.

  1993cited by this paper
• Modulation of rat liver S-adenosylmethionine synthetase activity by glutathione.

  1992cited by this paper
• Kinetic mechanism of the EcoRI DNA methyltransferase.

  1991cited by this paper
• Changes in expression of mRNA coding for glutathione S-transferase subunits 1-2 and 7 in cultured rat hepatocytes.

  1990cited by this paper
• Phosphatidylethanolamine N-methyltransferase in human red blood cell membrane preparations. Kinetic mechanism.

  1989cited by this paper
• Cellular uptake and metabolic reduction of pentavalent to trivalent arsenic as determinants of cytotoxicity and morphological transformation.

  1987cited by this paper
• Culture duration alters the glutathione content and sensitivity to ethacrynic acid of rat hepatocyte monolayer cultures

  1986cited by this paper
• The activity of UDP-glucuronyltransferase, sulphotransferase and glutathione-S-transferase in primary cultures of rat hepatocytes.

  1986cited by this paper
• Purification and Kinetic Mechanism of Human Brain Soluble Catechol‐O‐Methyltransferase

  1985cited by this paper
• Changes in the concentration of seven forms of cytochrome P-450 in primary cultures of adult rat hepatocytes.

  1985cited by this paper
• Activities of several phase I and phase II xenobiotic biotransformation enzymes in cultured hepatocytes from male and female rats.

  1985cited by this paper
• Arsenic uptake and metabolism by liver cells is dependent on arsenic oxidation state.

  1983cited by this paper
• Kinetic studies on the O-methylation of dopamine by human brain membrane-bound catechol O-methyltransferase.

  1982cited by this paper
• Kinetic studies on the O-methylation of dopamine by human brain membrane-bound catechol O-methyltransferase.

  1982cited by this paper
• The kinetic properties and reaction mechanism of histamine methyltransferase from human skin.

  1980cited by this paper
• Drug metabolism and effects of carcinogens in cultured hepatic cells.

  1979cited by this paper
• 1 Steady State Kinetics

  1970cited by this paper

• Arsenic

  2022cites this paper
• The processes and mechanism of antimony sequestered by red blood cells and its metabolic conjugation with hemoglobin in rats.

  2018cites this paper
• Chapter 28 – Arsenic

  2015cites this paper
• Mathematical modeling of the effects of glutathione on arsenic methylation

  2014cites this paper
• Mutational analysis of residues in human arsenic (III) methyltransferase (hAS3MT) belonging to 5 Å around S-adenosylmethionine (SAM).

  2014cites this paper
• Residues in Human Arsenic (+3 Oxidation State) Methyltransferase Forming Potential Hydrogen Bond Network around S-adenosylmethionine

  2013cites this paper
• Identification of the Third Binding Site of Arsenic in Human Arsenic (III) Methyltransferase

  2013cites this paper
• Arsenic Binding to Proteins

  2013cites this paper
• Utilizing toxicogenomic data to understand chemical mechanism of action in risk assessment.

  2013cites this paper
• Investigations on arsenite induced premature senescence in human vascular endothelial cells

  2013influential citation
• Arsenic: An Overview of Applications, Health, and Environmental Concerns and Removal Processes

  2011cites this paper
• Functional and structural evaluation of cysteine residues in the human arsenic (+3 oxidation state) methyltransferase (hAS3MT).

  2011cites this paper
• Mathematical model insights into arsenic detoxification

  2011cites this paper
• New insights into the mechanism of arsenite methylation with the recombinant human arsenic (+3) methyltransferase (hAS3MT).

  2010cites this paper
• Structure-function roles of four cysteine residues in the human arsenic (+3 oxidation state) methyltransferase (hAS3MT) by site-directed mutagenesis.

  2009cites this paper
• Development of a human physiologically based pharmacokinetic (PBPK) model for inorganic arsenic and its mono- and di-methylated metabolites

  2008cites this paper
• CHAPTER 19 – Arsenic

  2007cites this paper
• Research toward the development of a biologically based dose response assessment for inorganic arsenic carcinogenicity: a progress report.

  2007cites this paper