Dissociation of the 47‐Kilodalton Protein Phosphorylation From Degranulation and Superoxide Production in Neutrophils

No abstract is available for this paper.

• Publication year

  1988

• Venue

  Journal of Leukocyte Biology

• Publication date

  1988-01-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1002/jlb.43.1.18PMID 2826626
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  1986cited by this paper
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  1986cited by this paper
• Studies and perspectives of protein kinase C.

  1986influential reference
• Reversal by protein kinase C inhibitor of suppressive actions of phorbol-12-myristate-13-acetate on polyphosphoinositide metabolism and cytosolic Ca2+ mobilization in thrombin-stimulated human platelets.

  1986cited by this paper
• Co-activation of protein kinase C and NADPH oxidase in the plasma membrane of neutrophil cytoplasts.

  1986influential reference
• The inhibition of neutrophil responsiveness caused by phorbol esters is blocked by the protein kinase C inhibitor H7.

  1986cited by this paper
• Protein kinase C phosphorylates human platelet inositol trisphosphate 5'-phosphomonoesterase, increasing the phosphatase activity.

  1986cited by this paper
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  1985cited by this paper
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  1985influential reference
• Calcium-mobilizing receptors, polyphosphoinositides, and the generation of second messengers.

  1985cited by this paper
• The molecular basis of communication within the cell.

  1985cited by this paper
• Serotonin secretion from human platelets may be modified by Ca2+-activated, phospholipid-dependent myosin phosphorylation.

  1984cited by this paper
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  1984cited by this paper
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  1984cited by this paper
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  1984cited by this paper
• The NADPH oxidase of human polymorphonuclear leukocytes. Evidence for regulation by multiple signals.

  1984cited by this paper
• Phorbol 12-myristate 13-acetate activates rabbit neutrophils without an apparent rise in the level of intracellular free calcium.

  1983cited by this paper
• Phorbol diester receptor copurifies with protein kinase C.

  1983cited by this paper
• Endogenous protein phosphorylation by resting and activated human neutrophils.

  1983influential reference
• Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters.

  1982cited by this paper
• Chemotactic factor enhancement of superoxide release from fluoride and phorbol myristate acetate stimulated neutrophils.

  1981influential reference
• Enhancement of neutrophils function as a result of prior exposure to chemotactic factor.

  1980cited by this paper
• Increased production of superoxide anion by macrophages exposed in vitro to muramyl dipeptide or lipopolysaccharide

  1980cited by this paper
• Desensitization and deactivation of the secretory responsiveness of rabbit neutrophils induced by the chemotactic peptide, formyl-methionyl-leucyl-phenylalanine.

  1979cited by this paper
• In vitro responses of human neutrophils to N-formyl-methionyl-leucyl-phenylalanine: correlation with effects of acute bacterial infection.

  1979cited by this paper
• Superoxide generation by digitonin-stimulated guinea pig granulocytes. A basis for a continuous assay for monitoring superoxide production and for the study of the activation of the generating system.

  1978cited by this paper
• Single-step separation of red blood cells. Granulocytes and mononuclear leukocytes on discontinuous density gradients of Ficoll-Hypaque.

  1974cited by this paper
• The microestimation of succinate and the extinction coefficient of cytochrome c.

  1959cited by this paper

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  1995cites this paper
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  1995cites this paper
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  1994cites this paper
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  1994cites this paper
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  1993cites this paper
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