Duox1 is the main source of hydrogen peroxide in the rat thyroid cell line PCCl3.

No abstract is available for this paper.

• Publication year

  2007

• Venue

  Experimental Cell Research

• Publication date

  2007-11-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/J.YEXCR.2007.06.011PMID 17643428
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• A novel host defense system of airways is defective in cystic fibrosis.

  2007cited by this paper
• Airway Epithelial Cell Migration and Wound Repair by ATP-mediated Activation of Dual Oxidase 1*

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• Three mutations (p.Q36H, p.G418fsX482, and g.IVS19-2A>C) in the dual oxidase 2 gene responsible for congenital goiter and iodide organification defect.

  2006cited by this paper
• Faculty Opinions recommendation of Identification of the maturation factor for dual oxidase. Evolution of an eukaryotic operon equivalent.

  2006cited by this paper
• Identification of the Maturation Factor for Dual Oxidase

  2006cited by this paper
• Identification of a Novel Partner of Duox

  2005cited by this paper
• Differential regulation of dual NADPH oxidases/peroxidases, Duox1 and Duox2, by Th1 and Th2 cytokines in respiratory tract epithelium

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• Identification of a Novel Partner of Duox EFP1, A THIOREDOXIN-RELATED PROTEIN*

  2005cited by this paper
• The phylogeny, ontogeny, anatomy and regulation of the iodine metabolizing thyroid

  2005cited by this paper
• Dual oxidase2 is expressed all along the digestive tract.

  2005cited by this paper
• Dual Oxidase-2 Has an Intrinsic Ca2+-dependent H2O2-generating Activity*

  2005cited by this paper
• A Direct Role for Dual Oxidase in Drosophila Gut Immunity

  2005cited by this paper
• Regulated hydrogen peroxide production by Duox in human airway epithelial cells.

  2005cited by this paper
• Persistent mild hypothyroidism associated with novel sequence variants of the DUOX2 gene in two siblings

  2005cited by this paper
• Structural and functional characterization of the two human ThOX/Duox genes and their 5′-flanking regions

  2004cited by this paper
• Correlation between the loss of thyroglobulin iodination and the expression of thyroid-specific proteins involved in iodine metabolism in thyroid carcinomas.

  2003cited by this paper
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  2003cited by this paper
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  2003cited by this paper
• Structural changes in the angiofollicular units between active and hypofunctioning follicles align with differences in the epithelial expression of newly discovered proteins involved in iodine transport and organification.

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• Characterization of ThOX proteins as components of the thyroid H(2)O(2)-generating system.

  2002cited by this paper
• Regulation of thyroid cell proliferation by TSH and other factors: a critical evaluation of in vitro models.

  2001cited by this paper
• Expression of Nicotinamide Adenine Dinucleotide Phosphate Oxidase Flavoprotein DUOX Genes and Proteins in Human Papillary and Follicular Thyroid Carcinomas

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• Cloning of tissue-specific genes using serial analysis of gene expression and a novel computational substraction approach.

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• Expression of reduced nicotinamide adenine dinucleotide phosphate oxidase (ThoX, LNOX, Duox) genes and proteins in human thyroid tissues.

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  2000cited by this paper
• Cloning of Two Human Thyroid cDNAs Encoding New Members of the NADPH Oxidase Family*

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• Conservation of histone H2A/H2B intergene regions: a role for the H2B specific element in divergent transcription.

  1988cited by this paper
• One- and two-step transformations of rat thyroid epithelial cells by retroviral oncogenes

  1987cited by this paper
• Purification of bovine thyroid peroxidase.

  1977influential reference
• [Production of peroxide in the thyroid].

  1971cited by this paper

• Bisphenol A interferes with TTF-1 and PAX8 modulation of dual oxidase 2 human thyroid promoter activity

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• Bisphenol A increases hydrogen peroxide generation by thyrocytes both in vivo and in vitro

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• NKX2.5 is expressed in papillary thyroid carcinomas and regulates differentiation in thyroid cells

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• [Transient congenital hypothyroidism due to biallelic defects of DUOX2 gene. Two clinical cases].

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  2015cites this paper
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  2014cites this paper
• Roles of DUOX-Mediated Hydrogen Peroxide in Metabolism, Host Defense, and Signaling

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• Diabetes mellitus increases reactive oxygen species production in the thyroid of male rats.

  2013influential citation
• Maneb causes pro-oxidant effects in the hippocampus of Nrf2 knockout mice.

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  2012cites this paper
• Superoxide dismutase 3-mediated cell survival and proliferation

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• Cell biology of H2O2 generation in the thyroid: investigation of the control of dual oxidases (DUOX) activity in intact ex vivo thyroid tissue and cell lines.

  2011cites this paper
• Identification and functional analysis of novel dual oxidase 2 (DUOX2) mutations in children with congenital or subclinical hypothyroidism.

  2011cites this paper
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  2010cites this paper
• Compound heterozygosity for a novel hemizygous missense mutation and a partial deletion affecting the catalytic core of the H2O2‐generating enzyme DUOX2 associated with transient congenital hypothyroidism

  2010cites this paper
• Extracellular superoxide dismutase is a thyroid differentiation marker down-regulated in cancer.

  2010cites this paper
• All-trans retinoic acid mediates DUOX2 expression and function in respiratory tract epithelium.

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