Increased serum levels of YKL-40 in patients with inflammatory bowel disease

No abstract is available for this paper.

• Publication year

  2003

• Venue

  International Journal of Colorectal Disease

• Publication date

  2003-05-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1007/s00384-002-0446-zPMID 12673492
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Effect of ulcerative colitis activity on plasma concentration of transforming growth factor beta1.

  2001cited by this paper
• [Observations on the increased serum levels of YKL-40 in patients with rheumatoid arthritis and osteoarthritis].

  2001cited by this paper
• Serum YKL-40 in patients with inflammatory bowel disease

  2001cited by this paper
• Can we influence fibrosis in Crohn's disease?

  2001cited by this paper
• YKL-40 (cartilage gp-39) induces proliferative events in cultured chondrocytes and synoviocytes and increases glycosaminoglycan synthesis in chondrocytes.

  2001cited by this paper
• Altered Response of Intestinal Mucosal Fibroblasts to Profibrogenic Cytokines in Inflammatory Bowel Disease

  2001cited by this paper
• Inflammation Location, But Not Type, Determines the Increase in TGF-&bgr;1 and IGF-1 Expression and Collagen Deposition in IBD Intestine

  2001cited by this paper
• IGF-I and procollagen alpha1(I) are coexpressed in a subset of mesenchymal cells in active Crohn's disease.

  2000cited by this paper
• Chondrex (YKL‐40), a potential new serum fibrosis marker in patients with alcoholic liver disease

  2000cited by this paper
• Strictures in Crohn’s disease are characterised by an accumulation of mast cells colocalised with laminin but not with fibronectin or vitronectin

  1999cited by this paper
• Myofibroblasts. II. Intestinal subepithelial myofibroblasts.

  1999cited by this paper
• YKL-40, a mammalian member of the chitinase family, is a matrix protein of specific granules in human neutrophils.

  1998cited by this paper
• A simple clinical colitis activity index

  1998cited by this paper
• Chitotriosidase, a chitinase, and the 39-kDa human cartilage glycoprotein, a chitin-binding lectin, are homologues of family 18 glycosyl hydrolases secreted by human macrophages.

  1998cited by this paper
• Human cartilage glycoprotein-39 as a candidate autoantigen in rheumatoid arthritis.

  1997cited by this paper
• Plasma YKL-40: a new potential marker of fibrosis in patients with alcoholic cirrhosis?

  1997cited by this paper
• Serum YKL-40 levels in healthy children and adults. Comparison with serum and synovial fluid levels of YKL-40 in patients with osteoarthritis or trauma of the knee joint.

  1996cited by this paper
• Effect of nicotine on rectal mucus and mucosal eicosanoids.

  1994cited by this paper
• Human cartilage gp-39, a major secretory product of articular chondrocytes and synovial cells, is a mammalian member of a chitinase protein family.

  1993cited by this paper
• Identification of proteins secreted by human osteoblastic cells in culture

  1992cited by this paper
• Human synovial cells secrete a 39 kDa protein similar to a bovine mammary protein expressed during the non-lactating period.

  1990cited by this paper
• Classification of inflammatory bowel disease.

  1989cited by this paper
• Lectin histochemistry in ulcerative colitis and Crohn's disease.

  1989cited by this paper
• Chitin and chitosan : sources, chemistry, biochemistry, physical properties, and applications

  1989cited by this paper
• Isolation and characterization of a novel 39 kilodalton whey protein from bovine mammary secretions collected during the nonlactating period.

  1988cited by this paper
• Development of a Crohn's disease activity index. National Cooperative Crohn's Disease Study.

  1976cited by this paper

• A Simplified Method for Evaluating Chitin-Binding Activity Applied to YKL-40 (HC-gp39, CHI3L1) and Chitotriosidase

  2024cites this paper
• Evolutionary insights into sequence modifications governing chitin recognition and chitinase inactivity in YKL-40 (HC-gp39, CHI3L1)

  2024cites this paper
• Multimodal single-cell analyses reveal mechanisms of perianal fistula in diverse patients with Crohn's disease.

  2024cites this paper
• Recently Updated Role of Chitinase 3-like 1 on Various Cell Types as a Major Influencer of Chronic Inflammation

  2024cites this paper
• Machine learning-based B cell-related diagnostic biomarker signature and molecular subtypes characteristic of ulcerative colitis

  2024cites this paper
• Irreversible evolutionary loss of chitin‐degrading ability in the chitinase‐like protein Ym1 under positive selection in rodents

  2023cites this paper
• Predictive value of serum YKL-40, interleukin-37, and cancer antigen 125 panel in noninvasive staging of endometriosis

  2023cites this paper
• Urinary chitinase 3-like 1 and intestinal fatty-acid binding proteins are not elevated in children with inflammatory bowel disease

  2022cites this paper
• The role of YKL-40 in the pathogenesis of autoimmune diseases: a comprehensive review

  2022influential citation
• A novel biomarker in acute cholecystitis: YKL-40.

  2022cites this paper
• Chitinase-3-like Protein 1 (YKL-40): A New Biomarker of Inflammation in Pyoderma Gangrenosum

  2021cites this paper
• Neurochemical biomarkers to study CNS effects of COVID‐19: A narrative review and synthesis

  2021cites this paper
• A Review of Selected IBD Biomarkers: From Animal Models to Bedside

  2021cites this paper
• Chitinases and Chitinase-Like Proteins as Therapeutic Targets in Inflammatory Diseases, with a Special Focus on Inflammatory Bowel Diseases

  2021cites this paper
• Serum biomarkers of fibrostenotic Crohn's disease: Where are we now?

  2020cites this paper
• Chitinase 3-Like 1, Nestin, and Testin Proteins as Novel Biomarkers of Potential Clinical Use in Colorectal Cancer: A Review.

  2020cites this paper
• The Ulcerative Colitis Response Index for Detection of Mucosal Healing in Patients Treated With Anti-tumour Necrosis Factor.

  2020cites this paper
• CSF levels of HoxB3 and YKL-40 may predict conversion from clinically isolated syndrome to relapsing remitting multiple sclerosis.

  2020cites this paper
• Serum Biomarkers for Inflammatory Bowel Disease

  2020cites this paper
• Cerebrospinal fluid levels of glial marker YKL-40 strongly associated with axonal injury in HIV infection

  2019cites this paper
• Cerebrospinal fluid chitinase-3-like protein 1 level is not an independent predictive factor for the risk of clinical conversion in radiologically isolated syndrome

  2019cites this paper
• Determination of serum YKL-40 levels in patients with brucellosis

  2019cites this paper
• Evaluation of serum chitinase-3-like protein 1, pentraxin-3, and neutrophil gelatinase-associated lipocalin levels in diabetic foot cases

  2019cites this paper
• Fibrosis and Stricturing Disease in Crohn’s Disease

  2019cites this paper
• Identification of Chitinase-3-Like Protein 1 as a Novel Neutrophil Antigenic Target in Crohn’s Disease

  2019cites this paper
• Alteration in Uterine Protease-Activated Receptor 2 Expression in Preterm Birth Induced Experimentally in Brp-39 Null Mutant Mice

  2018cites this paper
• Clinical, Cellular and Serologic Biomarkers of Intestinal Fibrosis

  2018cites this paper
• Lessons to be learned from serum biomarkers in psoriasis and IBD – the potential role in SpA

  2017cites this paper
• Clinical Utility of YKL-40 in Polymyositis/dermatomyositis-associated Interstitial Lung Disease

  2017cites this paper
• European Crohn's and Colitis Organisation Topical Review on Prediction, Diagnosis and Management of Fibrostenosing Crohn's Disease.

  2016cites this paper
• Urinary markers in the early stage of nephropathy in patients with childhood-onset type 1 diabetes

  2016cites this paper
• Biomarkers of intestinal fibrosis – one step towards clinical trials for stricturing inflammatory bowel disease

  2016cites this paper
• Novel biomarkers of fibrosis in Crohn's disease.

  2016cites this paper
• Towards new measures of inflammation in spondyloarthritis

  2016cites this paper
• Chitinase 3-like proteins as diagnostic and prognostic biomarkers of multiple sclerosis

  2015cites this paper
• YKL-40 level in gingival crevicular fluid from patients with periodontitis and type 2 diabetes.

  2015cites this paper
• Quantitative Real-Time PCR Analysis of YKL-40 and Its Comparison with Mammalian Chitinase mRNAs in Normal Human Tissues Using a Single Standard DNA

  2015cites this paper
• Molecular Analysis of Inflammatory Bowel Disease: Clinically Useful Tools for Diagnosis, Response Prediction, and Monitoring of Targeted Therapy

  2015cites this paper
• Increased expression and possible role of chitinase 3-like-1 in a colitis-associated carcinoma model.

  2014cites this paper
• Circulating YKL-40 in patients with essential thrombocythemia and polycythemia vera treated with the novel histone deacetylase inhibitor vorinostat.

  2014cites this paper
• Establishment of a quantitative PCR system for discriminating chitinase-like proteins: catalytically inactive breast regression protein-39 and Ym1 are constitutive genes in mouse lung

  2014cites this paper
• Mechanisms of Cigarette Smoke-Induced Inflammation and the Exacerbated Response to Bacteria in Mice

  2014cites this paper
• New treatment and markers of prognosis for idiopathic pulmonary fibrosis: lessons learned from translational research

  2013cites this paper
• YKL-40 in induced sputum after allergen bronchial provocation in atopic asthma.

  2012cites this paper
• Provisional chapter Fibrosis in Crohn ’ s Disease

  2012cites this paper
• A phase 1 open‐label trial shows that smad7 antisense oligonucleotide (GED0301) does not increase the risk of small bowel strictures in Crohn's disease

  2012cites this paper
• Significant Association of Elevated Concentration of Plasma YKL‐40 with Disease Severity in Patients With Pelvic Inflammatory Disease

  2012cites this paper
• Can YKL-40 be a new inflammatory biomarker in cardiovascular disease?

  2012cites this paper
• Exacerbation of Experimental Autoimmune Encephalomyelitis in the Absence of Breast Regression Protein 39/Chitinase 3-Like 1

  2012cites this paper
• Fibrosis in Crohn’s Disease

  2012cites this paper
• Chitinase 3-like-1 expression in colonic epithelial cells as a potentially novel marker for colitis-associated neoplasia.

  2011influential citation
• Predictors of fibrostenotic Crohn's disease

  2011cites this paper
• Serum and BALF YKL-40 levels are predictors of survival in idiopathic pulmonary fibrosis.

  2011cites this paper
• Chitinase effects on immune cell response in neuromyelitis optica and multiple sclerosis

  2011cites this paper
• Promoter polymorphisms in the chitinase 3-like 1 gene influence the serum concentration of YKL-40 in Danish patients with rheumatoid arthritis and in healthy subjects

  2011cites this paper
• Differential expression and function of breast regression protein 39 (BRP-39) in murine models of subacute cigarette smoke exposure and allergic airway inflammation

  2011cites this paper
• The Chitinase-like Protein YKL-40 Is Secreted by Airway Epithelial Cells at Base Line and in Response to Compressive Mechanical Stress*

  2010cites this paper
• Cerebrospinal fluid chitinase 3-like 1 levels are associated with conversion to multiple sclerosis.

  2010cites this paper
• YKL-40—A Protein in the Field of Translational Medicine: A Role as a Biomarker in Cancer Patients?

  2010cites this paper
• Increased YKL-40 expression in patients with carotid atherosclerosis.

  2010cites this paper
• YKL-40: a new biomarker in cardiovascular disease?

  2010cites this paper
• Potential role of chitinase 3-like-1 in inflammation-associated carcinogenic changes of epithelial cells.

  2009cites this paper
• Plasma YKL-40: a potential new cancer biomarker?

  2009cites this paper
• YKL-40: a novel marker shared by chronic inflammation and oncogenic transformation.

  2009cites this paper
• Chitinase 3-Like-1 (CHI3L1): A Putative Disease Marker at the Interface of Proteomics and Glycomics

  2008cites this paper
• Elevated cerebrospinal fluid and serum YKL-40 levels are not associated with symptomatic vasospasm in patients with aneurysmal subarachnoid haemorrhage.

  2008cites this paper
• Serum levels of YKL-40 increases in patients with acute myocardial infarction

  2008cites this paper
• Serum YKL‐40 as a marker of disease activity and stricture formation in patients with Crohn's disease

  2008cites this paper
• Is YKL-40 a new therapeutic target in cancer?

  2007cites this paper
• The contribution of Greek gastroenterologists in the international clinical and basic research of inflammatory bowel disease

  2007cites this paper
• A CHI3L1 gene polymorphism is associated with serum levels of YKL-40, a novel sarcoidosis marker.

  2007cites this paper
• YKL-40 protein expression in normal adult human tissues – an immunohistochemical study

  2007cites this paper
• Noninvasive Tests for Liver Fibrosis

  2006cites this paper
• Noninvasive tests for liver fibrosis.

  2006cites this paper
• Studies on serum YKL-40 as a biomarker in diseases with inflammation, tissue remodelling, fibroses and cancer.

  2006influential citation
• YKL-40, a new inflammatory marker with relation to insulin resistance and with a role in endothelial dysfunction and atherosclerosis

  2006cites this paper
• Serum YKL-40, A New Prognostic Biomarker in Cancer Patients?

  2006influential citation
• High SerumConcentration of YKL-40 Is Associatedwith Short Survival in Patients with AcuteMyeloid Leukemia

  2005cites this paper
• Circulating YKL‐40 ‡ levels during human endotoxaemia

  2005cites this paper
• YKL-40 Expression is Associated with Poorer Response to Radiation and Shorter Overall Survival in Glioblastoma

  2005cites this paper
• Increased serum YKL-40 in patients with pulmonary sarcoidosis--a potential marker of disease activity?

  2005cites this paper
• Human cartilage glycoprotein 39: structure, biological function and application for clinical diagnostics

  2005cites this paper
• High Serum Concentration of YKL-40 Is Associated with Short Survival in Patients with Acute Myeloid Leukemia

  2005cites this paper
• Cross-sectional association of 10 molecular markers of bone, cartilage, and synovium with disease activity and radiological joint damage in patients with hip osteoarthritis: the ECHODIAH cohort.

  2005cites this paper
• Specific targeting of gene expression to a subset of human trabecular meshwork cells using the chitinase 3-like 1 promoter.

  2004cites this paper
• YKL-40 as a marker of joint involvement in inflammatory bowel disease.

  2003cites this paper
• World Journal of Gastroenterology

  year unknowncites this paper