In vivo interactions between &agr;7 nicotinic acetylcholine receptor and nuclear peroxisome proliferator‐activated receptor‐&agr;: Implication for nicotine dependence

No abstract is available for this paper.

• Publication year

  2017

• Venue

  Neuropharmacology

• Publication date

  2017-05-15

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1016/j.neuropharm.2017.03.005PMID 28279662PMCID PMC5410388
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Effects of K-877, a novel selective PPARα modulator, on small intestine contribute to the amelioration of hyperlipidemia in low-density lipoprotein receptor knockout mice.

  2017cited by this paper
• PPAR Agonists: I. Role of Receptor Subunits in Alcohol Consumption in Male and Female Mice.

  2016cited by this paper
• PPAR Agonists: II. Fenofibrate and Tesaglitazar Alter Behaviors Related to Voluntary Alcohol Consumption.

  2016cited by this paper
• Effects of K-877, a novel selective PPARα modulator (SPPARMα), in dyslipidaemic patients: A randomized, double blind, active- and placebo-controlled, phase 2 trial.

  2016cited by this paper
• Role of the satiety factor oleoylethanolamide in alcoholism

  2016cited by this paper
• Early adolescent nicotine exposure affects later-life cocaine reward in mice.

  2016cited by this paper
• Understanding the Bases of Function and Modulation of α7 Nicotinic Receptors: Implications for Drug Discovery

  2016cited by this paper
• Differential Roles of α6β2* and α4β2* Neuronal Nicotinic Receptors in Nicotine- and Cocaine-Conditioned Reward in Mice

  2015cited by this paper
• Early investigational drugs targeting PPAR-α for the treatment of metabolic disease

  2015cited by this paper
• Transcriptome Analysis of K-877 (a Novel Selective PPARα Modulator (SPPARMα))-Regulated Genes in Primary Human Hepatocytes and the Mouse Liver.

  2015cited by this paper
• Initial Evaluation of Fenofibrate for Efficacy in Aiding Smoking Abstinence.

  2015cited by this paper
• Inhibition of monoacylglycerol lipase reduces nicotine withdrawal

  2015cited by this paper
• Antidepressants and Changes in Concentration of Endocannabinoids and N-Acylethanolamines in Rat Brain Structures

  2014cited by this paper
• Antidepressants and Changes in Concentration of Endocannabinoids and N-Acylethanolamines in Rat Brain Structures

  2014cited by this paper
• Effects of methoxsalen, a CYP2A5/6 inhibitor, on nicotine dependence behaviors in mice.

  2014cited by this paper
• Dissociation of tolerance and nicotine withdrawal-associated deficits in contextual fear.

  2014cited by this paper
• Genetic variation within the Chrna7 gene modulates nicotine reward‐like phenotypes in mice

  2014influential reference
• The role of fatty acid amide hydrolase inhibition in nicotine reward and dependence.

  2013cited by this paper
• PPARα Regulates Cholinergic-Driven Activity of Midbrain Dopamine Neurons via a Novel Mechanism Involving α7 Nicotinic Acetylcholine Receptors

  2013cited by this paper
• The cannabinoid CB2 receptor is necessary for nicotine-conditioned place preference, but not other behavioral effects of nicotine in mice

  2013cited by this paper
• The cannabinoid CB2 receptor is necessary for nicotine-conditioned place preference, but not other behavioral effects of nicotine in mice

  2013cited by this paper
• Selective peroxisome proliferator-activated receptorα modulators (SPPARMα): The next generation of peroxisome proliferator-activated receptor α-agonists

  2013cited by this paper
• Novel Use of a Lipid-Lowering Fibrate Medication to Prevent Nicotine Reward and Relapse: Preclinical Findings

  2012cited by this paper
• Reward, addiction, withdrawal to nicotine.

  2011cited by this paper
• Blockade of nicotine reward and reinstatement by activation of alpha-type peroxisome proliferator-activated receptors.

  2011cited by this paper
• The role of nicotinic acetylcholine receptor (nAChR) α7 subtype in the functional interaction between nicotine and ethanol in mouse cerebellum.

  2011cited by this paper
• Alpha7 Nicotinic Acetylcholine Receptors Modulate Motivation to Self-Administer Nicotine: Implications for Smoking and Schizophrenia

  2011cited by this paper
• Fenofibrate

  2011cited by this paper
• Positive allosteric modulators as an approach to nicotinic acetylcholine receptor-targeted therapeutics: advantages and limitations.

  2011cited by this paper
• Effects of the endogenous PPAR‐α agonist, oleoylethanolamide on MDMA‐induced cognitive deficits in mice

  2010cited by this paper
• Effects of nicotine in experimental animals and humans: an update on addictive properties.

  2009cited by this paper
• beta2-Nicotinic acetylcholine receptor availability during acute and prolonged abstinence from tobacco smoking.

  2009cited by this paper
• Endogenous Fatty Acid Ethanolamides Suppress Nicotine-Induced Activation of Mesolimbic Dopamine Neurons through Nuclear Receptors

  2008cited by this paper
• Differential Role of Nicotinic Acetylcholine Receptor Subunits in Physical and Affective Nicotine Withdrawal Signs

  2008influential reference
• Decreased withdrawal symptoms but normal tolerance to nicotine in mice null for the alpha7 nicotinic acetylcholine receptor subunit.

  2007cited by this paper
• Nicotine Dependence and Reward Differ between Adolescent and Adult Male Mice

  2007cited by this paper
• The β2 but not α7 subunit of the nicotinic acetylcholine receptor is required for nicotine-conditioned place preference in mice

  2006influential reference
• Differential gene expression in mouse primary hepatocytes exposed to the peroxisome proliferator-activated receptor alpha agonists

  2006cited by this paper
• The beta2 but not alpha7 subunit of the nicotinic acetylcholine receptor is required for nicotine-conditioned place preference in mice.

  2006influential reference
• Bupropion for the treatment of nicotine withdrawal and craving

  2006cited by this paper
• Differential gene expression in mouse primary hepatocytes exposed to the peroxisome proliferator-activated receptor α agonists

  2006cited by this paper
• Nicotine place preference in the mouse: influences of prior handling, dose and strain and attenuation by nicotinic receptor antagonists

  2006influential reference
• The selective alpha7 nicotinic acetylcholine receptor agonist PNU-282987 [N-[(3R)-1-Azabicyclo[2.2.2]oct-3-yl]-4-chlorobenzamide hydrochloride] enhances GABAergic synaptic activity in brain slices and restores auditory gating deficits in anesthetized rats.

  2005cited by this paper
• The Selective α7 Nicotinic Acetylcholine Receptor Agonist PNU-282987 [N-[(3R)-1-Azabicyclo[2.2.2]oct-3-yl]-4-chlorobenzamide Hydrochloride] Enhances GABAergic Synaptic Activity in Brain Slices and Restores Auditory Gating Deficits in Anesthetized Rats

  2005cited by this paper
• The nuclear receptor peroxisome proliferator-activated receptor-alpha mediates the anti-inflammatory actions of palmitoylethanolamide.

  2005cited by this paper
• Discovery and structure-activity relationship of quinuclidine benzamides as agonists of alpha7 nicotinic acetylcholine receptors.

  2005cited by this paper
• The Nuclear Receptor Peroxisome Proliferator-Activated Receptor-α Mediates the Anti-Inflammatory Actions of Palmitoylethanolamide

  2005cited by this paper
• Immunolocalization of peroxisome proliferator-activated receptors and retinoid X receptors in the adult rat CNS.

  2004cited by this paper
• Characterization of Spontaneous and Precipitated Nicotine Withdrawal in the Mouse

  2003cited by this paper
• Bupropion for the treatment of nicotine dependence in spit tobacco users: a pilot study.

  2002cited by this paper
• Nicotine Receptor Inactivation Decreases Sensitivity to Cocaine

  2001influential reference
• Isolation and Characterization of Peroxisome Proliferator-activated Receptor (PPAR) Interacting Protein (PRIP) as a Coactivator for PPAR*

  2000cited by this paper
• The PPARs: from orphan receptors to drug discovery.

  2000influential reference
• Dramatic decreases in brain reward function during nicotine withdrawal

  1998cited by this paper
• Acetylcholine receptors containing the β2 subunit are involved in the reinforcing properties of nicotine

  1998cited by this paper
• Mechanism of action of fibrates on lipid and lipoprotein metabolism.

  1998cited by this paper
• Molecular cloning, functional properties, and distribution of rat brain alpha 7: a nicotinic cation channel highly permeable to calcium

  1993cited by this paper

• α7 nicotinic acetylcholine receptor and depression: Mechanistic insights and therapeutic prospects.

  2025cites this paper
• Nicotine and neuronal nicotinic acetylcholine receptors: unraveling the mechanisms of nicotine addiction

  2025cites this paper
• Alcohol-induced liver injury is mediated via α4-containing nicotinic acetylcholine receptors expressed in hepatocytes.

  2025cites this paper
• Docosahexaenoic acid provides a protective effect in amygdala-kindled rats by activating peroxisome proliferator-activated receptor α.

  2025cites this paper
• Neurobiology of Stress-Induced Nicotine Relapse

  2024cites this paper
• A cholinergic circuit that relieves pain despite opioid tolerance.

  2023cites this paper
• Resveratrol inhibits nicotine-induced conditioned place preference in mice

  2023cites this paper
• Roles of Simvastatin and Sildenafil in Modulation of Cranial Irradiation-Induced Bystander Multiple Organs Injury in Rats

  2021cites this paper
• The effects of moxidectin nicotine-conditioned cue on nicotine-seeking behavior in mice

  2021cites this paper
• Rewarding effect of ethanol-induced conditioned place preference in mice: Effect of the monoterpenoid linalool.

  2021cites this paper
• No Correlation between Fagerstrom Test for Nicotine Dependence Scores to Lipopolysaccharide Marker in Thai Smokers

  2021cites this paper
• Roles of the Functional Interaction between Brain Cholinergic and Dopaminergic Systems in the Pathogenesis and Treatment of Schizophrenia and Parkinson’s Disease

  2021cites this paper
• Linalool attenuates acquisition and reinstatement and accelerates the extinction of nicotine-induced conditioned place preference in male mice

  2021influential citation
• N-Oleoylglycine and N-Oleoylalanine Do Not Modify Tolerance to Nociception, Hyperthermia, and Suppression of Activity Produced by Morphine

  2021cites this paper
• Conjugated Linoleic Acid and Brain Metabolism: A Possible Anti-Neuroinflammatory Role Mediated by PPARα Activation

  2021cites this paper
• Repurposing Peroxisome Proliferator-Activated Receptor Agonists in Neurological and Psychiatric Disorders

  2021cites this paper
• Beta-caryophyllene inhibits cocaine addiction-related behavior by activation of PPARα and PPARγ: repurposing a FDA-approved food additive for cocaine use disorder

  2020cites this paper
• Therapeutic Potential of Peroxisome Proliferator-Activated Receptor (PPAR) Agonists in Substance Use Disorders: A Synthesis of Preclinical and Human Evidence

  2020influential citation
• Cholinergic Receptors and Addiction.

  2020cites this paper
• Recent findings in the pharmacology of inhaled nicotine: Preclinical and clinical in vivo studies.

  2020cites this paper
• Regulation of the deleterious effects of binge-like exposure to alcohol during adolescence by α7 nicotinic acetylcholine receptor agents: prevention by pretreatment with a α7 negative allosteric modulator and emulation by a α7 agonist in alcohol-preferring (P) male and female rats

  2020cites this paper
• Advances in smoking cessation pharmacotherapy: Non-nicotinic approaches in animal models.

  2020cites this paper
• Behavioral Pharmacology of the Cholinergic System

  2020cites this paper
• Endocannabinoid-Like Lipid Neuromodulators in the Regulation of Dopamine Signaling: Relevance for Drug Addiction

  2020cites this paper
• N‐Oleoyl‐glycine reduces nicotine reward and withdrawal in mice

  2019influential citation
• Randomized Placebo-Controlled Clinical Trials Testing Gemfibrozil for Smoking Cessation and Melatonin for Alcohol-related Sleeping Problems

  2019cites this paper
• Impact of modulation of the α7 nicotinic acetylcholine receptor on nicotine reward in the mouse conditioned place preference test

  2019cites this paper
• The α7 nicotinic receptor silent agonist R-47 prevents and reverses paclitaxel-induced peripheral neuropathy in mice without tolerance or altering nicotine reward and withdrawal.

  2019cites this paper
• Inhibition of N‐acylethanolamine acid amidase reduces nicotine‐induced dopamine activation and reward

  2019cites this paper
• New insights on the effects of varenicline on nicotine reward, withdrawal and hyperalgesia in mice

  2018cites this paper
• Testing the PPAR hypothesis of tobacco use disorder in humans: A randomized trial of the impact of gemfibrozil (a partial PPARα agonist) in smokers

  2018cites this paper
• Self-administered nicotine increases fat metabolism and suppresses weight gain in male rats

  2018cites this paper
• Validation of Brain Angiotensin System Blockade as a Novel Drug Target in Pharmacological Treatment of Neuropsychiatric Disorders

  2017cites this paper
• Insights into Nicotinic Receptor Signaling in Nicotine Addiction: Implications for Prevention and Treatment

  2017cites this paper
• A Systems Biology Approach to Investigating Sex Differences in Cardiac Hypertrophy

  2017cites this paper