Structure, expression and chromosomal mapping of TKT from man and mouse: a new subclass of receptor tyrosine kinases with a factor VIII-like domain.

No abstract is available for this paper.

• Publication year

  1993

• Venue

  Oncogene

• Publication date

  1993-12-01

• Fields of study

  Biology, Medicine

• Identifiers
  PMID 8247548
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Progressive sequence alignment as a prerequisitetto correct phylogenetic trees

  2007cited by this paper
• The endothelial-specific receptor tyrosine kinase, tek, is a member of a new subfamily of receptors.

  1993cited by this paper
• Molecular cloning and characterization of a novel receptor protein tyrosine kinase from human placenta.

  1993cited by this paper
• cDNA cloning of mouse ret proto-oncogene and its sequence similarity to the cadherin superfamily.

  1993cited by this paper
• A novel endothelial cell surface receptor tyrosine kinase with extracellular epidermal growth factor homology domains

  1992cited by this paper
• A putative receptor tyrosine kinase with unique structural topology.

  1991cited by this paper
• Localization of the TRK proto-oncogene to human chromosome bands 1q23-1q24.

  1991cited by this paper
• axl, a transforming gene isolated from primary human myeloid leukemia cells, encodes a novel receptor tyrosine kinase

  1991cited by this paper
• trkB, a neural receptor protein-tyrosine kinase: evidence for a full-length and two truncated receptors

  1991cited by this paper
• Two additional protein-tyrosine kinases expressed in human lung: fourth member of the fibroblast growth factor receptor family and an intracellular protein-tyrosine kinase.

  1991cited by this paper
• The A5 antigen, a candidate for the neuronal recognition molecule, has homologies to complement components and coagulation factors.

  1991cited by this paper
• cDNA cloning and characterization of eck, an epithelial cell receptor protein-tyrosine kinase in the eph/elk family of protein kinases

  1990cited by this paper
• cDNA cloning of a mouse mammary epithelial cell surface protein reveals the existence of epidermal growth factor-like domains linked to factor VIII-like sequences.

  1990cited by this paper
• Six genes of the human connexin gene family coding for gap junctional proteins are assigned to four different human chromosomes.

  1990cited by this paper
• The structure and insertion of integral proteins in membranes.

  1990cited by this paper
• trkB, a novel tyrosine protein kinase receptor expressed during mouse neural development.

  1989cited by this paper
• Two putative protein-tyrosine kinases identified by application of the polymerase chain reaction.

  1989cited by this paper
• Purification and complementary DNA cloning of a receptor for basic fibroblast growth factor.

  1989cited by this paper
• cDNA cloning and expression of the human A-type platelet-derived growth factor (PDGF) receptor establishes structural similarity to the B-type PDGF receptor.

  1989cited by this paper
• Molecular and biochemical characterization of the human trk proto-oncogene

  1989cited by this paper
• Primary structure of a putative receptor for a ligand of the insulin family.

  1989cited by this paper
• The protein kinase family: conserved features and deduced phylogeny of the catalytic domains.

  1988cited by this paper
• Growth factor receptor tyrosine kinases.

  1988cited by this paper
• ret transforming gene encodes a fusion protein homologous to tyrosine kinases

  1987cited by this paper
• A novel putative tyrosine kinase receptor encoded by the eph gene.

  1987cited by this paper
• Complete cDNA and derived amino acid sequence of human factor V.

  1987cited by this paper
• Insulin‐like growth factor I receptor primary structure: comparison with insulin receptor suggests structural determinants that define functional specificity.

  1986cited by this paper
• Structure of the receptor for platelet-derived growth factor helps define a family of closely related growth factor receptors

  1986cited by this paper
• The human insulin receptor cDNA: the structural basis for hormone-activated transmembrane signalling.

  1985cited by this paper
• Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes

  1985cited by this paper
• Characterization of the human factor VIII gene

  1984cited by this paper
• Compilation and analysis of sequences upstream from the translational start site in eukaryotic mRNAs.

  1984cited by this paper
• Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells

  1984cited by this paper
• Structure of human factor VIII

  1984cited by this paper

• Discoid Domain Receptors Signaling in Macrophages-Mediated Diseases

  2025cites this paper
• Identification and In Silico Characterization of an Alternatively Spliced Novel Transcript of Human DDR2 Gene.

  2025cites this paper
• Discoidin Domain Receptors in Tumor Biology and Immunology: Progression and Challenge

  2025cites this paper
• Extracellular matrix-induced signaling pathways in mesenchymal stem/stromal cells

  2023cites this paper
• Multifaceted collagen-DDR1 signaling in cancer.

  2023cites this paper
• Discoidin domain receptor inhibitors as anticancer agents: A systematic review on recent development of DDRs inhibitors, their resistance and structure activity relationship.

  2022cites this paper
• Complex roles of discoidin domain receptor tyrosine kinases in cancer

  2021cites this paper
• The role of basement membranes in cardiac biology and disease

  2021cites this paper
• Discoidin domain receptors (DDRs): Potential implications in periodontitis

  2021cites this paper
• A molecular cascade underlying articular cartilage degeneration.

  2020cites this paper
• Insulin/IGF signaling and discoidin domain receptors: An emerging functional connection.

  2019cites this paper
• Discoidin domain receptor 2: An emerging pharmacological drug target for prospective therapy against osteoarthritis

  2019cites this paper
• From academic research to founding a company: the story of AiCuris

  2019cites this paper
• Protective effects of the pericellular matrix of chondrocyte on articular cartilage against the development of osteoarthritis.

  2018cites this paper
• Myosin Phosphatase Rho-interacting Protein Regulates DDR1-mediated Collagen Tractional Remodeling

  2017cites this paper
• Activation of Discoidin Domain Receptors by collagen VI and collagen I fibrils

  2017cites this paper
• Investigating the activation mechanism of discoidin domain receptor 1 using advanced microscopy techniques

  2017cites this paper
• Inhibition of Discoidin Domain Receptor 1 Reduces Collagen-mediated Tumorigenicity in Pancreatic Ductal Adenocarcinoma

  2017cites this paper
• Le récepteur à domaine discoïdine de type 1 : un acteur majeur des pathologies rénales chroniques et aiguës

  2016cites this paper
• Discoidin Domain Receptor 2 in Development of Osteoarthritis

  2016cites this paper
• Small molecule discoidin domain receptor kinase inhibitors and potential medical applications.

  2015cites this paper
• Genetic Analysis Identifies DDR2 as a Novel Gene Affecting Bone Mineral Density and Osteoporotic Fractures in Chinese Population

  2015cites this paper
• DDRs: receptors that mediate adhesion, migration and invasion in breast cancer cells

  2015cites this paper
• The DDR Receptor Family

  2015cites this paper
• Experimental Evaluation of Discoid Domain Receptor 2 as an Ideal Target for Development of Disease-Modifying Osteoarthritis Drugs

  2015cites this paper
• Discoidin domain receptor functions in physiological and pathological conditions.

  2014cites this paper
• A tale of two collagen receptors, integrin β1 and discoidin domain receptor 1, in epithelial cell differentiation.

  2012cites this paper
• Structure of the Discoidin Domain Receptor 1 Extracellular Region Bound to an Inhibitory Fab Fragment Reveals Features Important for Signaling

  2012cites this paper
• R-Type Lectin Families

  2012cites this paper
• Discoidin domain receptor tyrosine kinases: new players in cancer progression

  2012cites this paper
• Gene expression profiling of luminal B breast cancers reveals NHERF1 as a new marker of endocrine resistance

  2011cites this paper
• Gene expression profiling of luminal B breast cancers reveals NHERF1 as a new marker of endocrine resistance

  2011cites this paper
• Discoidin Domain Receptors role in human diseases.

  2011cites this paper
• DDR1 regulates the stabilization of cell surface E‐cadherin and E‐cadherin‐mediated cell aggregation

  2010cites this paper
• Inhibition of collagen fibrillogenesis by cells expressing soluble extracellular domains of DDR1 and DDR2.

  2010cites this paper
• Regulation of collagen fibrillogenesis by cell-surface expression of kinase dead DDR2.

  2009cites this paper
• A novel dwarfism with gonadal dysfunction due to loss-of-function allele of the collagen receptor gene, Ddr2, in the mouse.

  2008cites this paper
• New therapeutic approaches to liver fibrosis: a practicable route?

  2008cites this paper
• Lessons from genetic forms of osteoarthritis for the pathogenesis of the disease.

  2007cites this paper
• Discoidin domain receptor 2 inhibits fibrillogenesis of collagen type 1.

  2006cites this paper
• Isolation and Characterization of an Epithelial-specific Receptor Tyrosine Kinase from an Ovarian Cancer Cell Line 1

  2005cites this paper
• Activation of the Discoidin Domain Receptor 2 Induces Expression of Matrix Metalloproteinase 13 Associated with Osteoarthritis in Mice*♦

  2005cites this paper
• Expression profiles of tyrosine kinases in cultured follicular papilla cells versus dermal fibroblasts.

  2004cites this paper
• Liver Fibrosis and DDR2 Signaling

  2003cites this paper
• New insights into binding interfaces of coagulation factors V and VIII and their homologues lessons from high resolution crystal structures.

  2002cites this paper
• Formation of the Heart and Its Regulation

  2001cites this paper
• Discoidin domain receptors and their ligand, collagen, are temporally regulated in fetal rat fibroblasts in vitro.

  2001cites this paper
• cDNA Array Analysis of Altered Gene Expression in Human Endothelial Cells in Response to Chlamydia pneumoniae Infection

  2001cites this paper
• DDR2 receptor promotes MMP-2-mediated proliferation and invasion by hepatic stellate cells.

  2001cites this paper
• The Role of the Extracellular Matrix and Its Receptors in Modulating Cardiac Development

  2001cites this paper
• Collagen-receptor signaling in health and disease.

  2001cites this paper
• DDR 2 receptor promotes MMP-2 – mediated proliferation and invasion by hepatic stellate cells

  2001cites this paper
• Consistent and Selective Expression of the Discoidin Domain Receptor-1 Tyrosine Kinase in Human Brain Tumors

  2000cites this paper
• Upregulation of Tyrosine Kinase TKT by the Epstein-Barr Virus Transactivator Zta

  2000cites this paper
• Discoidin domain receptor 1 (DDR1) signaling in PC12 cells: activation of juxtamembrane domains in PDGFR/DDR/TrkA chimeric receptors

  2000cites this paper
• Growth Factor Receptor Tyrosine Kinases: Cell Adhesion Kinase Family Suggests a Novel Signaling Mechanism in Cancer

  2000cites this paper
• Discoidin domain receptors: structural relations and functional implications

  1999cites this paper
• Comparative tyrosine‐kinase profiles in colorectal cancers: Enhanced arg expression in carcinoma as compared with adenoma and normal mucosa

  1999cites this paper
• The mouse X-linked juvenile retinoschisis cDNA: expression in photoreceptors.

  1999cites this paper
• Expression of human F8B, a gene nested within the coagulation factor VIII gene, produces multiple eye defects and developmental alterations in chimeric and transgenic mice.

  1999cites this paper
• Genetic and physical mapping of the dreher locus on mouse chromosome 1.

  1999cites this paper
• The discoidin domain family revisited: New members from prokaryotes and a homology‐based fold prediction

  1998cites this paper
• Nef proteins of distinct HIV-1 or -2 isolates differ in their binding properties for HCK: isolation of a novel Nef binding factor with characteristics of an adaptor protein.

  1998cites this paper
• Tyrosine-614, the major autophosphorylation site of the receptor tyrosine kinase HEK2, functions as multi-docking site for SH2-domain mediated interactions

  1998cites this paper
• Molecular approaches to diagnosis and management of ovarian cancer

  1997cites this paper
• The discoidin domain receptor tyrosine kinases are activated by collagen.

  1997cites this paper
• Localization of the mouse gene encoding tyrosine kinase receptor type 10 on distal Chromosome 1

  1997cites this paper
• Identification of a novel contactin‐associated transmembrane receptor with multiple domains implicated in protein–protein interactions

  1997cites this paper
• Human SAK related to the PLK/polo family of cell cycle kinases shows high mRNA expression in testis.

  1997cites this paper
• An orphan receptor tyrosine kinase family whose members serve as nonintegrin collagen receptors.

  1997cites this paper
• Prognostic significance of polo-like kinase (PLK) expression in non-small cell lung cancer

  1997cites this paper
• Growth factor receptor tyrosine kinases

  1997cites this paper
• The genomic structure of discoidin receptor tyrosine kinase.

  1996cites this paper
• A tyrosine kinase profile of prostate carcinoma.

  1996cites this paper
• Pediatric brain tumors express multiple receptor tyrosine kinases including novel cell adhesion kinases.

  1996cites this paper
• Kinetics of the interaction between the human factor VIIIa subunits: effects of pH, ionic strength, Ca2+ concentration, heparin, and activated protein C-catalyzed proteolysis.

  1995cites this paper
• Molecular cloning of tyrosine kinases in the early Xenopus embryo: Identification of eck‐related genes expressed in cranial neural crest cells of the second (Hyoid) Arch

  1995cites this paper
• Localization of an epithelial-specific receptor kinase (EDDR1) to chromosome 6q16.

  1995cites this paper
• Tumorinvasion — die Rolle der Rezeptoren

  1995cites this paper
• Expression patterns of the novel receptor-like tyrosine kinase, DDR, in human breast tumours.

  1995cites this paper
• Mapping of the receptor protein-tyrosine kinase 10 to human chromosome 1q21-q23 and mouse chromosome 1H1-5 by fluorescence in situ hybridization.

  1995cites this paper
• Radiation induction of the receptor tyrosine kinase gene Ptk-3 in normal rat astrocytes.

  1995cites this paper
• Five Trk receptors in the zebrafish.

  1995cites this paper
• The eukaryotic protein kinase superfamily: kinase (catalytic) domain structure and classification 1

  1995cites this paper
• Distinct structural characteristics of discoidin I subfamily receptor tyrosine kinases and complementary expression in human cancer.

  1995cites this paper
• Tyrosine protein kinase expression in long‐term quiescent WI‐38 cells following growth factor simulation

  1995cites this paper
• Cck-2, recepteur a tyrosine-kinase

  1994cites this paper
• Induction and down-regulation of PLK, a human serine/threonine kinase expressed in proliferating cells and tumors.

  1994cites this paper
• Receptor protein-tyrosine kinases and their signal transduction pathways.

  1994cites this paper
• Human and Xenopus mo15 messenger-RNA are highly conserved but show different patterns of expression in adult tissues.

  1994cites this paper
• Isolation and characterization of an epithelial-specific receptor tyrosine kinase from an ovarian cancer cell line.

  1994cites this paper
• Gene Expression Profiling for Molecular Identification of

  year unknowncites this paper