Transcriptional downregulation of tight junction protein ZO-1 in active coeliac disease is reversed after a gluten-free diet.

No abstract is available for this paper.

• Publication year

  2004

• Venue

  Digestive and Liver Disease

• Publication date

  2004-05-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/J.DLD.2004.01.013PMID 15191203
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2002cited by this paper
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  2000cited by this paper
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  2000cited by this paper
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  1999cited by this paper
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  1999cited by this paper
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  1998cited by this paper
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  1998cited by this paper
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  1998cited by this paper
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  1998cited by this paper
• Molecular architecture of tight junctions.

  1998cited by this paper
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  1997cited by this paper
• Screening for celiac disease: a prospective study on the value of noninvasive tests.

  1995cited by this paper
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  1995cited by this paper
• Revised criteria for diagnosis of coeliac disease. Report of Working Group of European Society of Paediatric Gastroenterology and Nutrition.

  1990cited by this paper
• The immunopathology of the small intestinal reaction in gluten-sensitivity.

  1989cited by this paper
• Interferon-gamma directly affects barrier function of cultured intestinal epithelial monolayers.

  1989cited by this paper
• Lactulose/mannitol test: an ideal screen for celiac disease.

  1989cited by this paper
• Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction.

  1987cited by this paper
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  1986cited by this paper

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  2014cites this paper
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  2014cites this paper
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  2014cites this paper
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