Hmx1 is required for the normal development of somatosensory neurons in the geniculate ganglion.

No abstract is available for this paper.

• Publication year

  2012

• Venue

  Developmental Biology

• Publication date

  2012-05-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/J.YDBIO.2012.02.022PMID 22586713PMCID PMC3710741
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Brn3a and Islet1 Act Epistatically to Regulate the Gene Expression Program of Sensory Differentiation

  2011cited by this paper
• Retinal Dystrophy In The Oculo-auricular Syndrome Due to HMX1 Mutation

  2011cited by this paper
• Epibranchial placode‐derived neurons produce BDNF required for early sensory neuron development

  2011cited by this paper
• Epibranchial ganglia orchestrate the development of the cranial neurogenic crest

  2010influential reference
• A symphony of inner ear developmental control genes

  2010cited by this paper
• Genetic analyses of fancy rat-derived mutations.

  2010cited by this paper
• A robust and high-throughput Cre reporting and characterization system for the whole mouse brain

  2009influential reference
• Schwann cell precursors from nerve innervation are a cellular origin of melanocytes in skin.

  2009influential reference
• Mouse H6 Homeobox 1 (Hmx1) mutations cause cranial abnormalities and reduced body mass

  2009influential reference
• Altered neuronal lineages in the facial ganglia of Hoxa2 mutant mice.

  2008cited by this paper
• Mutation in the human homeobox gene NKX5-3 causes an oculo-auricular syndrome.

  2008influential reference
• Cell lineage in mammalian craniofacial mesenchyme.

  2008cited by this paper
• A central role for Islet1 in sensory neuron development linking sensory and spinal gene regulatory programs

  2008cited by this paper
• Embryonic origin of gustatory cranial sensory neurons.

  2007cited by this paper
• Brn3a target gene recognition in embryonic sensory neurons.

  2007cited by this paper
• DNAse I pre-treatment markedly enhances detection of nuclear cyclin-dependent kinase inhibitor p57Kip2 and BrdU double immunostaining in embryonic rat brain

  2007cited by this paper
• Regulation of cell fate in the sensory epithelia of the inner ear

  2007cited by this paper
• Specification and connectivity of neuronal subtypes in the sensory lineage

  2007influential reference
• Brn3a and Klf7 cooperate to control TrkA expression in sensory neurons.

  2006cited by this paper
• The molecular basis of neurosensory cell formation in ear development: a blueprint for hair cell and sensory neuron regeneration?

  2006cited by this paper
• Random mutagenesis of proximal mouse chromosome 5 uncovers predominantly embryonic lethal mutations.

  2005cited by this paper
• Hmx homeobox gene function in inner ear and nervous system cell-type specification and development.

  2005cited by this paper
• Brn3a-Expressing Retinal Ganglion Cells Project Specifically to Thalamocortical and Collicular Visual Pathways

  2005cited by this paper
• Vax genes ventralize the embryonic eye.

  2005cited by this paper
• Identification of Sox8 as a modifier gene in a mouse model of Hirschsprung disease reveals underlying molecular defect.

  2005cited by this paper
• Neurotrophic Factor Receptor Expression and in vitro Nerve Growth of Geniculate Ganglion Neurons That Supply Divergent Nerves

  2005influential reference
• Coordinated regulation of gene expression by Brn3a in developing sensory ganglia

  2004cited by this paper
• Building sensory receptors on the tongue

  2004cited by this paper
• Sonic hedgehog regulates the position of the trigeminal ganglia.

  2003cited by this paper
• Direct autoregulation and gene dosage compensation by POU-domain transcription factor Brn3a

  2003cited by this paper
• Hoxb1 neural crest preferentially form glia of the PNS

  2003cited by this paper
• Phox2b controls the development of peripheral chemoreceptors and afferent visceral pathways

  2003influential reference
• Optical Projection Tomography as a Tool for 3D Microscopy and Gene Expression Studies

  2002influential reference
• Defects in Sensory Axon Growth Precede Neuronal Death in Brn3a-Deficient Mice

  2001cited by this paper
• Vertebrate cranial placodes I. Embryonic induction.

  2001cited by this paper
• Contribution of cranial nerve ganglia to innervation of the walls of the rat external acoustic meatus

  2001cited by this paper
• Two homeobox genes define the domain of EphA3 expression in the developing chick retina.

  2000influential reference
• Hmx: an evolutionary conserved homeobox gene family expressed in the developing nervous system in mice and Drosophila.

  2000influential reference
• Modification of gene activity in mouse embryos in utero by a tamoxifen-inducible form of Cre recombinase.

  1998cited by this paper
• Cloning, characterization, and mapping of the mouse homeobox gene Hmx1.

  1998cited by this paper
• Sox10, a Novel Transcriptional Modulator in Glial Cells

  1998cited by this paper
• Expression and interactions of the two closely related homeobox genes Phox2a and Phox2b during neurogenesis.

  1997influential reference
• Innervation of the hard palate in the rat studied by anterograde transport of horseradish peroxidase conjugates

  1995cited by this paper
• Mouse rump-white mutation associated with an inversion of Chromosome 5

  1994cited by this paper
• Characterization of the homeobox-containing gene GH6 identifies novel regions of homeobox gene expression in the developing chick embryo.

  1994cited by this paper
• Asymmetric expression of a novel homeobox gene in vertebrate sensory organs

  1994cited by this paper
• The House Mouse

  1989cited by this paper
• Development of the peripheral nervous system from the neural crest.

  1988cited by this paper
• Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase.

  1988cited by this paper
• Contributions of placodal and neural crest cells to avian cranial peripheral ganglia.

  1983cited by this paper
• The early development of cranial sensory ganglia and the potentialities of their component cells studied in quail-chick chimeras.

  1982cited by this paper
• The early development of cranial sensory ganglia and the potentialities of their component cells studied in quail-chick chimeras.

  1982cited by this paper
• Neural crest and placodal contributions in the development of the glossopharyngeal‐vagal complex in the chick

  1980cited by this paper
• K. THEILER: THE HOUSE MOUSE. DEVELOPMENT AND NORMAL STAGES FROM FERTILIZATION TO 4 WEEKS OF AGE. 168 Seiten, 312 Abb. Springer Verlag, Berlin‐Heidelberg‐New York 1972, Preis: 124,— DM; 50,60 $

  1975cited by this paper
• The house mouse. Development and normal stages from fertilization to 4 weeks of age.

  1972cited by this paper

• Identification of a postnatal period of interdependent neurogenesis and apoptosis in peripheral neurons

  2024cites this paper
• A 76-base pair duplication within the enhancer region of the HMX1 gene causes sheep microtia.

  2024cites this paper
• Comparative analysis of Hmx expression and the distribution of neuronal somata in the trigeminal ganglion in lamprey and shark: insights into the homology of the trigeminal nerve branches and the evolutionary origin of the vertebrate jaw

  2023influential citation
• Hmx gene conservation identifies the origin of vertebrate cranial ganglia

  2022cites this paper
• Premature Vertebral Mineralization in hmx1-Mutant Zebrafish

  2022cites this paper
• Hmx1 regulates urfh1 expression in the craniofacial region in zebrafish

  2021cites this paper
• Hmx gene conservation identifies the evolutionary origin of vertebrate cranial ganglia

  2020cites this paper
• Vertebrate Sensory Ganglia: Common and Divergent Features of the Transcriptional Programs Generating Their Functional Specialization

  2020cites this paper
• Neuronal heterogeneity and stereotyped connectivity in the auditory afferent system

  2018cites this paper
• Further delineation of the oculoauricular syndrome phenotype: A new family with a novel truncating HMX1 mutation

  2018cites this paper
• Transcriptomes and neurotransmitter profiles of classes of gustatory and somatosensory neurons in the geniculate ganglion

  2017cites this paper
• The transcription factor Phox2b distinguishes between oral and non‐oral sensory neurons in the geniculate ganglion

  2017cites this paper
• A distal 594 bp ECR specifies Hmx1 expression in pinna and lateral facial morphogenesis and is regulated by the Hox-Pbx-Meis complex

  2016cites this paper
• Dynamic expression of transcription factor Brn3b during mouse cranial nerve development

  2016influential citation
• Insights into Neural Crest Evolution

  2016cites this paper
• Hmx1 Function In Lateral Facial Development

  2016influential citation
• Development of the Taste System

  2015cites this paper
• Abrogation of HMX1 function causes rare oculoauricular syndrome associated with congenital cataract, anterior segment dysgenesis, and retinal dystrophy.

  2015cites this paper
• Elucidating the role of Hmx1 during mouse development

  2015influential citation
• A comprehensive phenotypic and molecular analysis of congenital and childhood cataract

  2015cites this paper
• The genetics of auricular development and malformation: new findings in model systems driving future directions for microtia research.

  2014cites this paper
• The evolutionary history of vertebrate cranial placodes--I: cell type evolution.

  2014cites this paper
• A fate-map for cranial sensory ganglia in the sea lamprey

  2014influential citation
• Genetic evidence for conserved non-coding element function across species–the ears have it

  2014cites this paper
• A Dimerized HMX1 Inhibits EPHA6/epha4b in Mouse and Zebrafish Retinas

  2014cites this paper
• Identification of HMX1 target genes: A predictive promoter model approach

  2013cites this paper
• Hmx1 is a homeodomain transcription factor expressed in the developing eye, peripheral ganglia and branchial arches of avian and mammalian embryos

  2012cites this paper
• Zebrafish hmx1 promotes retinogenesis.

  2012cites this paper
• Deletion of a conserved regulatory element required for Hmx1 expression in craniofacial mesenchyme in the dumbo rat: a newly identified cause of congenital ear malformation

  2012cites this paper