Controlling fibrous capsule formation through long-term down-regulation of collagen type I (COL1A1) expression by nanofiber-mediated siRNA gene silencing.

No abstract is available for this paper.

• Publication year

  2013

• Venue

  Acta Biomaterialia

• Publication date

  Unknown publication date

• Fields of study

  Medicine, Materials Science, Engineering

• Identifiers
  DOI 10.1016/j.actbio.2012.09.029PMID 23036951PMCID PMC3523808
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Biomimetic surface modification of titanium surfaces for early cell capture by advanced electrospinning

  2012cited by this paper
• Increasing the Pore Size of Electrospun Scaffolds

  2011cited by this paper
• Polymeric Nanofibers in Tissue Engineering

  2011cited by this paper
• A peptide-based vector for efficient gene transfer in vitro and in vivo.

  2011cited by this paper
• Biological roles of the Delta family Notch ligand Dll4 in tumor and endothelial cells in ovarian cancer.

  2011cited by this paper
• Nanofiber-mediated controlled release of siRNA complexes for long term gene-silencing applications.

  2011cited by this paper
• Engineering Bi-Layer Nanofibrous Conduits for Peripheral Nerve Regeneration

  2011cited by this paper
• Identification of Novel Therapeutic Targets in Microdissected Clear Cell Ovarian Cancers

  2011cited by this paper
• A Peptide-based Vector for Efficient Gene Transfer In Vitro and In Vivo.

  2011cited by this paper
• Increasing electrospun scaffold pore size with tailored collectors for improved cell penetration.

  2011cited by this paper
• The promotion of stemness and pluripotency following feeder-free culture of embryonic stem cells on collagen-grafted 3-dimensional nanofibrous scaffold.

  2011cited by this paper
• Sciatic nerve regeneration in rats by a promising electrospun collagen/poly(ε-caprolactone) nerve conduit with tailored degradation rate

  2011cited by this paper
• Role of immune cells and inflammatory cytokines in regulation of fibrosis around silicone expander implants

  2010cited by this paper
• First-in-human mutation-targeted siRNA phase Ib trial of an inherited skin disorder.

  2010cited by this paper
• Device-based local delivery of siRNA against mammalian target of rapamycin (mTOR) in a murine subcutaneous implant model to inhibit fibrous encapsulation.

  2010cited by this paper
• Toxicity pathway focused gene expression profiling of PEI-based polymers for pulmonary applications.

  2010cited by this paper
• RNA interference by nanofiber-based siRNA delivery system.

  2010cited by this paper
• Targeting cyclin B1 through peptide-based delivery of siRNA prevents tumour growth

  2009cited by this paper
• The topographical effect of electrospun nanofibrous scaffolds on the in vivo and in vitro foreign body reaction.

  2009cited by this paper
• Tunable Thermosensitivity of Biodegradable Polymer Micelles of Poly(ε-caprolactone) and Polyphosphoester Block Copolymers

  2009cited by this paper
• A new potent secondary amphipathic cell-penetrating peptide for siRNA delivery into mammalian cells.

  2009cited by this paper
• Effect of Fiber Diameter and Alignment of Electrospun Polyurethane Meshes on Mesenchymal Progenitor Cells

  2009cited by this paper
• A matrix reservoir for improved control of non-viral gene delivery.

  2009cited by this paper
• Delivery of siRNA from lyophilized polymeric surfaces.

  2008cited by this paper
• The effect of the alignment of electrospun fibrous scaffolds on Schwann cell maturation.

  2008cited by this paper
• The influence of electrospun aligned poly(epsilon-caprolactone)/collagen nanofiber meshes on the formation of self-aligned skeletal muscle myotubes.

  2008cited by this paper
• Delivery of short interfering RNA using endosomolytic cell‐penetrating peptides

  2007cited by this paper
• Fibroblast differentiation in wound healing and fibrosis.

  2007cited by this paper
• Concurrent delivery of dexamethasone and VEGF for localized inflammation control and angiogenesis.

  2007cited by this paper
• Lung delivery studies using siRNA conjugated to TAT(48-60) and penetratin reveal peptide induced reduction in gene expression and induction of innate immunity.

  2007cited by this paper
• Aligned Protein–Polymer Composite Fibers Enhance Nerve Regeneration: A Potential Tissue‐Engineering Platform

  2007cited by this paper
• Cell-penetrating-peptide-mediated siRNA lung delivery.

  2007cited by this paper
• Surface adsorption of DNA to tissue engineering scaffolds for efficient gene delivery.

  2006cited by this paper
• A genetic strategy to treat sickle cell anemia by coregulating globin transgene expression and RNA interference

  2006cited by this paper
• Electrospun Micro- and Nanofibers for Sustained Delivery of Paclitaxel to Treat C6 Glioma in Vitro

  2006cited by this paper
• Macroporous condensed poly(tetrafluoroethylene). I. In vivo inflammatory response and healing characteristics.

  2006cited by this paper
• Kinetics and Mechanism of 2-Ethoxy-2-oxo-1,3,2-dioxaphospholane Polymerization Initiated by Stannous Octoate

  2006cited by this paper
• The lightweight and large porous mesh concept for hernia repair

  2005cited by this paper
• In vitro characterization of vascular endothelial growth factor and dexamethasone releasing hydrogels for implantable probe coatings.

  2005cited by this paper
• Peptide-based strategy for siRNA delivery into mammalian cells.

  2005cited by this paper
• A two-stage poly(ethylenimine)-mediated cytotoxicity: implications for gene transfer/therapy.

  2005cited by this paper
• Fibro-porous meshes made from polyurethane micro-fibers: effects of surface charge on tissue response.

  2005cited by this paper
• Calcitonin stimulates multiple stages of angiogenesis by directly acting on endothelial cells.

  2005cited by this paper
• Ordered surfactant-templated poly(3,4-ethylenedioxythiophene) (PEDOT) conducting polymer on microfabricated neural probes.

  2005cited by this paper
• Mammalian Target of Rapamycin Positively Regulates Collagen Type I Production via a Phosphatidylinositol 3-Kinase-independent Pathway*

  2004cited by this paper
• Highly Efficient Small Interfering RNA Delivery to Primary Mammalian Neurons Induces MicroRNA-Like Effects before mRNA Degradation

  2004cited by this paper
• Dexamethasone delays ulcer healing by inhibition of angiogenesis in rat stomachs.

  2004cited by this paper
• Biocompatibility and biofouling of MEMS drug delivery devices.

  2003cited by this paper
• Insight into the mechanism of the peptide-based gene delivery system MPG: implications for delivery of siRNA into mammalian cells.

  2003cited by this paper
• Effects of steroidal and non steroidal drugs on the neovascularization response induced by tumoral TA3 supernatant on CAM from chick embryo.

  2003cited by this paper
• Reducing capsular thickness and enhancing angiogenesis around implant drug release systems.

  2002cited by this paper
• The effect of microgeometry, implant thickness and polyurethane chemistry on the foreign body response to subcutaneous implants.

  2002cited by this paper
• Biological Responses to Materials

  2001cited by this paper
• Long- and short-term effects of biological hydrogels on capsule microvascular density around implants in rats.

  2001cited by this paper
• The effects of surface chemistry and adsorbed proteins on monocyte/macrophage adhesion to chemically modified polystyrene surfaces.

  2001cited by this paper
• Characterization of implantable biosensor membrane biofouling

  2000cited by this paper
• The glial scar and central nervous system repair.

  1999cited by this paper
• A novel potent strategy for gene delivery using a single peptide vector as a carrier.

  1999cited by this paper
• Liposomal transfection efficiency and toxicity on glioma cell lines: in vitro and in vitro studies*

  1998cited by this paper
• Screening mammography in 350 women with breast implants: prevalence and findings of implant complications.

  1992cited by this paper
• Foreign-body giant cells and polyurethane biostability: in vivo correlation of cell adhesion and surface cracking.

  1991cited by this paper

• Antithrombotic and antibacterial surface coating based on spiky silver nanoparticles: A counterattack against clotting and biofilm

  2026cites this paper
• Foreign body reaction: towards a macrophage-centered adverse outcome pathway for fibrotic encapsulation.

  2026cites this paper
• Don’t judge an implant by its cover: how the foreign body response and fibrotic capsule might be harnessed for good

  2026influential citation
• Scaling beyond the vagus nerve: historical and contemporary progress on electrode-based small-diameter peripheral nerve interfaces

  2026cites this paper
• Cell Contractile Forces Drive Spatiotemporal Morphogenesis in 4D Bioprinted Living Constructs.

  2025cites this paper
• Adhesive implant interfaces prevent fibrosis by disrupting mechanobiological feedback

  2025cites this paper
• In Vivo Cell Migration and Growth Within Electrospun Porous Nanofibrous Scaffolds with Different Pore Sizes in a Mouse Pouch Model

  2025cites this paper
• Preparation of carbon-based conductive hydrogels and their potential for promoting nerve regeneration

  2025cites this paper
• Semi-Interpenetrating Polymer Networks Incorporating Polygalacturonic Acid: Physical Characterization and In Vitro Biocompatibility

  2025cites this paper
• Development and Pilot in Vivo Testing of a Protocol for PLGA–Vancomycin Coatings on PTFE Used as Silicone-Implant Analogs

  2025cites this paper
• Organic films with amino groups on nanofibrous structure control innate immune response

  2025cites this paper
• Advanced Peptide Nanofibers in Delivery of Therapeutic Agents: Recent Trends, Limitations, and Critical Properties

  2025cites this paper
• Decoding the "Fingerprint" of Implant Materials: Insights into the Foreign Body Reaction.

  2024cites this paper
• Fiber configuration determines foreign body response of electrospun scaffolds: in vitro and in vivo assessments

  2024cites this paper
• Modulating Myofibroblastic Differentiation of Fibroblasts through Actin-MRTF Signaling Axis by Micropatterned Surfaces for Suppressed Implant-Induced Fibrosis

  2023cites this paper
• Immune response to foreign materials in spinal fusion surgery

  2023cites this paper
• Kompatibilitas bahan implan tulang hidroksiapatit dan karbonat hidroksiapatit di jaringan lunak

  2023cites this paper
• Histopathological changes in tissues surrounding vagal nerve stimulation generators: A retrospective analysis of revision surgeries

  2023cites this paper
• Oral delivery of RNAi for cancer therapy

  2023cites this paper
• Designing electrospun fiber platforms for efficient delivery of genetic material and genome editing tools.

  2022cites this paper
• Localized, on-demand, sustained drug delivery from biopolymer-based materials

  2022cites this paper
• Electrospun-Fibrous-Architecture-Mediated Non-Viral Gene Therapy Drug Delivery in Regenerative Medicine

  2022cites this paper
• A scoping review on the biomedical applications of polymeric particles

  2022cites this paper
• Electrospun Nanofibers for Cancer Therapy.

  2021cites this paper
• Ursachen für femorale Revisionen

  2021cites this paper
• Bio-inspired poly-DL-serine materials resist the foreign-body response

  2021cites this paper
• Implant Fibrosis and the Underappreciated Role of Myofibroblasts in the Foreign Body Reaction

  2021cites this paper
• Dielectric Elastomer Actuators, Neuromuscular Interfaces, and Foreign Body Response in Artificial Neuromuscular Prostheses: A Review of the Literature for an In Vivo Application

  2021cites this paper
• Additive manufacturing enables personalised porous high-density polyethylene surgical implant manufacturing with improved tissue and vascular ingrowth

  2021cites this paper
• MicroRNA-532-5p is implicated in the regulation of osteoporosis by forkhead box O1 and osteoblast differentiation

  2020cites this paper
• A tarsus construct of a novel branched polyethylene with good elasticity for eyelid reconstruction in vivo

  2020cites this paper
• Recent Advances in Anti-inflammatory Strategies for Implantable Biosensors and Medical Implants

  2020cites this paper
• The in vivo biocompatibility of novel tannic acid-collagen type I injectable bead scaffold material for breast reconstruction post-lumpectomy

  2020cites this paper
• Skin responses to biomaterials

  2020cites this paper
• Dealing with the Foreign‐Body Response to Implanted Biomaterials: Strategies and Applications of New Materials

  2020cites this paper
• A laser microdissection-based axotomy model incorporating the use of biomimicking fiber scaffolds reveals that microRNAs promote axon regeneration over long injury distances.

  2020cites this paper
• RNA interference in glial cells for nerve injury treatment

  2020cites this paper
• Bioactive‐Tissue‐Derived Nanocomposite Hydrogel for Permanent Arterial Embolization and Enhanced Vascular Healing

  2020cites this paper
• Clinical Opportunities for Continuous Biosensing and Closed-Loop Therapies

  2020cites this paper
• Cell penetrating peptides: the potent multi-cargo intracellular carriers

  2019cites this paper
• Decellularized Cortical Bone Scaffold Promotes Organized Neovascularization In Vivo

  2019cites this paper
• Bio-functional electrospun nanomaterials: From topology design to biological applications

  2019cites this paper
• Electrospinning Nanofibers for Therapeutics Delivery

  2019cites this paper
• Biomimicking Fiber Scaffold as an Effective In Vitro and In Vivo MicroRNA Screening Platform for Directing Tissue Regeneration

  2019cites this paper
• Reduced fibrous capsule formation at nano-engineered silicone surfaces via tantalum ion implantation.

  2019cites this paper
• Surface Modification by Divalent Main-Group-Elemental Ions for Improved Bone Remodeling To Instruct Implant Biofabrication.

  2019cites this paper
• Domesticating the foreign body response: Recent advances and applications.

  2019cites this paper
• Biofunctionalization of Silica Nanoparticles with Cell Penetrating Peptides: Adsorption Mechanism and Binding Energy Estimation.

  2019cites this paper
• Modulating Macrophage Phenotype by Sustained MicroRNA Delivery Improves Host‐Implant Integration

  2019cites this paper
• Chemical functionality of multidomain peptide hydrogels governs early host immune response.

  2019cites this paper
• DNA Hydrogel Assemblies: Bridging Synthesis Principles to Biomedical Applications

  2018cites this paper
• Induction of apoptosis in prostate cancer by ginsenoside Rh2

  2018cites this paper
• Electrospun membranes of PELCL/PCL-REDV loading with miRNA-126 for enhancement of vascular endothelial cell adhesion and proliferation.

  2018cites this paper
• Three-dimensional scaffold platform for controlled therapeutic drug and non-viral gene delivery to enhance nerve regeneration and remyelination in spinal cord injuries

  2018cites this paper
• Gene Silencing via PDA/ERK2‐siRNA‐Mediated Electrospun Fibers for Peritendinous Antiadhesion

  2018cites this paper
• Electrospinning: An enabling nanotechnology platform for drug delivery and regenerative medicine☆

  2018cites this paper
• Sustained delivery of siRNA/mesoporous silica nanoparticle complexes from nanofiber scaffolds for long-term gene silencing.

  2018cites this paper
• Instructive microenvironments in skin wound healing: Biomaterials as signal releasing platforms.

  2018cites this paper
• Commentary on: Novel Proteomic Assay of Breast Implants Reveals Proteins with Significant Binding Differences: Implications for Surface Coating and Biocompatibility.

  2018cites this paper
• Immunomodulation of Biomaterials by Controlling Macrophage Polarization.

  2018cites this paper
• Engineered Hydrogels for Local and Sustained Delivery of RNA‐Interference Therapies

  2017cites this paper
• Preparation and characterization of polycaprolactone–polyethylene glycol methyl ether and polycaprolactone–chitosan electrospun mats potential for vascular tissue engineering

  2017cites this paper
• Engineering approaches in siRNA delivery.

  2017cites this paper
• DESIGN OF ROBUST HYDROGEL BASED ON MUSSEL-INSPIRED CHEMISTRY

  2017cites this paper
• Nanofiber composites in gene delivery

  2017cites this paper
• Three-dimensional aligned nanofibers-hydrogel scaffold for controlled non-viral drug/gene delivery to direct axon regeneration in spinal cord injury treatment

  2017cites this paper
• Particle Disease: A Current Review of the Biological Mechanisms in Periprosthetic Osteolysis After Hip Arthroplasty

  2016cites this paper
• Nanofiber-mediated microRNA-126 delivery to vascular endothelial cells for blood vessel regeneration.

  2016cites this paper
• Increase of human prostate cancer cell (DU145) apoptosis by telmisartan through PPAR-delta pathway.

  2016cites this paper
• The Application of Nanotechnology for Implant Drug Release

  2016cites this paper
• Photocleavable Hydrogels for Light‐Triggered siRNA Release

  2016cites this paper
• Inflammasome components ASC and AIM2 modulate the acute phase of biomaterial implant-induced foreign body responses

  2016cites this paper
• Recent advancements in nanotechnological strategies in selection, design and delivery of biomolecules for skin regeneration.

  2016cites this paper
• Three-Dimensional Nanofiber Hybrid Scaffold Directs and Enhances Axonal Regeneration after Spinal Cord Injury.

  2016cites this paper
• MicroRNAs and their potential therapeutic applications in neural tissue engineering.

  2015cites this paper
• Molecular Events at Tissue–Biomaterial Interface

  2015cites this paper
• Foreign body giant cells in the foreign body reaction to implanted biomaterials, a systematic review

  2015cites this paper
• Co-delivery of siRNA and doxorubicin to cancer cells from additively manufactured implants

  2015cites this paper
• Signals mediating Klotho-induced neuroprotection in hippocampal neuronal cells.

  2015cites this paper
• Foreign Body Reaction to Subcutaneous Implants.

  2015cites this paper
• Nanofiber-mediated microRNA delivery to enhance differentiation and maturation of oligodendroglial precursor cells.

  2015cites this paper
• MicroRNA delivery for regenerative medicine.

  2015cites this paper
• The effects of nanofiber diameter and orientation on siRNA uptake and gene silencing.

  2015cites this paper
• CCN5 attenuates profibrotic phenotypes of fibroblasts through the Smad6-CCN2 pathway: Potential role in epidural fibrosis

  2015cites this paper
• The Crosstalk between Tissue Engineering and Pharmaceutical Biotechnology: Recent Advances and Future Directions.

  2015cites this paper
• Technologies for controlled, local delivery of siRNA.

  2015cites this paper
• Topographical effects on fiber-mediated microRNA delivery to control oligodendroglial precursor cells development.

  2015cites this paper
• Electrospun nanofibers as versatile interfaces for efficient gene delivery

  2014cites this paper
• Biomedical Implant Capsule Formation: Lessons Learned and the Road Ahead

  2014cites this paper
• The use of gene activated matrix to mediate effective SMAD2 gene silencing against hypertrophic scar.

  2014cites this paper
• Design of gene-activated matrix for the repair of skin and cartilage

  2014cites this paper
• Injectable Dopamine-Modified Poly(ethylene glycol) Nanocomposite Hydrogel with Enhanced Adhesive Property and Bioactivity

  2014cites this paper
• Evaluation and advancement of electrocorticographic brain-machine interfaces for individuals with upper-limb paralysis

  2014cites this paper
• Nanolayered siRNA dressing for sustained localized knockdown.

  2013cites this paper
• Osteolysis around total knee arthroplasty: a review of pathogenetic mechanisms.

  2013cites this paper