The Rapid Induction of HLA-E Is Essential for the Survival of Antigen-Activated Naive CD4 T Cells from Attack by NK Cells

No abstract is available for this paper.

• Publication year

  2010

• Venue

  Journal of Immunology

• Publication date

  2010-11-15

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.4049/jimmunol.1000176PMID 20952676
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Regulatory NK-Cell Functions in Inflammation and Autoimmunity

  2009cited by this paper
• Clinical Significance of HLA-E*0103 Homozygosity on Survival After Allogeneic Hematopoietic Stem-Cell Transplantation

  2009cited by this paper
• Killers and beyond: NK‐cell‐mediated control of immune responses

  2008cited by this paper
• NK Cells Lyse T Regulatory Cells That Expand in Response to an Intracellular Pathogen1

  2008cited by this paper
• The relationship between circulating natural killer cells after reduced intensity conditioning hematopoietic stem cell transplantation and relapse-free survival and graft-versus-host disease

  2008cited by this paper
• Natural killer cells recruited into lymph nodes inhibit alloreactive T-cell activation through perforin-mediated killing of donor allogeneic dendritic cells.

  2008cited by this paper
• Functions of natural killer cells

  2008cited by this paper
• Regulatory NK Cells Suppress Antigen-Specific T Cell Responses1

  2008cited by this paper
• Negative signaling by inhibitory receptors: the NK cell paradigm

  2008cited by this paper
• Human natural killer cells.

  2008cited by this paper
• Reconstitution of the immune system after hematopoietic stem cell transplantation in humans

  2008cited by this paper
• Rapid natural killer cell recovery determines outcome after T-cell-depleted HLA-identical stem cell transplantation in patients with myeloid leukemias but not with acute lymphoblastic leukemia

  2007cited by this paper
• Regulation of activated CD4+ T cells by NK cells via the Qa-1-NKG2A inhibitory pathway.

  2007cited by this paper
• Antigen-activated human T lymphocytes express cell-surface NKG2D ligands via an ATM/ATR-dependent mechanism and become susceptible to autologous NK- cell lysis.

  2007cited by this paper
• Homozygous Status for HLA-E*0103 Confers Protection from Acute Graft-Versus-Host Disease and Transplant-Related Mortality in HLA-Matched Sibling Hematopoietic Stem Cell Transplantation

  2006cited by this paper
• Natural killer cell behavior in lymph nodes revealed by static and real-time imaging

  2006cited by this paper
• Effector and regulatory events during natural killer–dendritic cell interactions

  2006cited by this paper
• Factors associated with early molecular remission after T cell-depleted allogeneic stem cell transplantation for chronic myelogenous leukemia.

  2006cited by this paper
• NK cell recognition.

  2005cited by this paper
• NK-dependent DC maturation is mediated by TNFα and IFNγ released upon engagement of the NKp30 triggering receptor

  2005cited by this paper
• Transforming growth factor-beta controls T helper type 1 cell development through regulation of natural killer cell interferon-gamma.

  2005cited by this paper
• NK Cells Inhibit T Cell Proliferation via p21-Mediated Cell Cycle Arrest1

  2005cited by this paper
• Suppression of tumor formation in lymph nodes by L-selectin–mediated natural killer cell recruitment

  2005cited by this paper
• Inflammatory mediators are insufficient for full dendritic cell activation and promote expansion of CD4+ T cell populations lacking helper function

  2005cited by this paper
• Mechanism of natural killer (NK) cell regulatory role in experimental autoimmune encephalomyelitis.

  2005cited by this paper
• Transforming growth factor-β controls T helper type 1 cell development through regulation of natural killer cell interferon-γ

  2005cited by this paper
• Long-term mixed chimerism after immunologic conditioning and MHC-mismatched stem-cell transplantation is dependent on NK-cell tolerance.

  2005cited by this paper
• MIC and other NKG2D ligands: from none to too many.

  2005cited by this paper
• NK-dependent DC maturation is mediated by TNFalpha and IFNgamma released upon engagement of the NKp30 triggering receptor.

  2005cited by this paper
• NK-cell reconstitution after haploidentical hematopoietic stem-cell transplantations: immaturity of NK cells and inhibitory effect of NKG2A override GvL effect.

  2005cited by this paper
• Natural killer cells distinguish innocuous and destructive forms of pancreatic islet autoimmunity.

  2004cited by this paper
• Killing of human immunodeficiency virus-infected primary T-cell blasts by autologous natural killer cells is dependent on the ability of the virus to alter the expression of major histocompatibility complex class I molecules.

  2004cited by this paper
• Induced recruitment of NK cells to lymph nodes provides IFN-gamma for T(H)1 priming.

  2004cited by this paper
• Induced recruitment of NK cells to lymph nodes provides IFN-γ for TH1 priming

  2004cited by this paper
• The Abundant NK Cells in Human Secondary Lymphoid Tissues Require Activation to Express Killer Cell Ig-Like Receptors and Become Cytolytic1

  2004cited by this paper
• Distinct roles of IL-12 and IL-15 in human natural killer cell activation by dendritic cells from secondary lymphoid organs.

  2004cited by this paper
• Viral infection and Toll‐like receptor agonists induce a differential expression of type I and λ interferons in human plasmacytoid and monocyte‐derived dendritic cells

  2004cited by this paper
• Activated, But Not Resting, T Cells Can Be Recognized and Killed by Syngeneic NK Cells 1

  2003cited by this paper
• The natural killer cell‐mediated killing of autologous dendritic cells is confined to a cell subset expressing CD94/NKG2A, but lacking inhibitory killer Ig‐like receptors

  2003cited by this paper
• CD56bright natural killer cells are present in human lymph nodes and are activated by T cell-derived IL-2: a potential new link between adaptive and innate immunity.

  2003cited by this paper
• Dendritic-cell control of pathogen-driven T-cell polarization

  2003cited by this paper
• Human Dendritic Cells Activate Resting Natural Killer (NK) Cells and Are Recognized via the NKp30 Receptor by Activated NK Cells

  2002cited by this paper
• Reciprocal Activating Interaction between Natural Killer Cells and Dendritic Cells

  2002cited by this paper
• Contact-dependent Stimulation and Inhibition of Dendritic Cells by Natural Killer Cells

  2002cited by this paper
• Effectiveness of Donor Natural Killer Cell Alloreactivity in Mismatched Hematopoietic Transplants

  2002cited by this paper
• Human natural killer cells : a unique innate immunoregulatory role for the CD 56 bright subset

  2001cited by this paper
• Human natural killer cells: a unique innate immunoregulatory role for the CD56bright subset

  2001cited by this paper
• Human natural killer cells: a unique innate immunoregulatory role for the CD56(bright) subset.

  2001cited by this paper
• Targeting of human dendritic cells by autologous NK cells.

  1999cited by this paper
• Annexin V used for measuring apoptosis in the early events of cellular cytotoxicity.

  1999cited by this paper
• A novel method for measuring CTL and NK cell-mediated cytotoxicity using annexin V and two-color flow cytometry.

  1999cited by this paper
• Application of tyramide signal amplification system to immunohistochemistry: A potent method to localize antigens that are not detectable by ordinary method

  1999cited by this paper
• Role of natural killer cells and TCR gamma delta T cells in acute autoimmune encephalomyelitis.

  1998cited by this paper
• HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C

  1998cited by this paper
• Role of natural killer cells and TCRγ δ T cells in acute autoimmune encephalomyelitis

  1998cited by this paper
• HLA-E surface expression depends on binding of TAP-dependent peptides derived from certain HLA class I signal sequences.

  1998cited by this paper
• HLA-E is a major ligand for the natural killer inhibitory receptor CD94/NKG2A.

  1998cited by this paper
• The CD94/NKG2-A inhibitory receptor complex is involved in natural killer cell-mediated recognition of cells expressing HLA-G1.

  1997cited by this paper
• Regulation of Experimental Autoimmune Encephalomyelitis by Natural Killer (NK) Cells

  1997cited by this paper
• Recognition of virus-infected cells by natural killer cell clones is controlled by polymorphic target cell elements

  1993cited by this paper
• CD16- CD56+ natural killer cells after bone marrow transplantation.

  1992cited by this paper
• Human natural killer cells.

  1979cited by this paper

• Endothelial Cell Secretome Alterations Induced by Inflammatory Stress

  2026cites this paper
• Metabolic adaptations rewire CD4+ T cells in a subset-specific manner in human critical illness with and without sepsis

  2026cites this paper
• Germline natural killer cell receptors modulating the T cell response

  2024cites this paper
• Inhibitory KIRs decrease HLA class II-mediated protection in Type 1 Diabetes

  2024cites this paper
• Role of NKG2a/c+CD8+ T cells in pathogenic versus non-pathogenic SIV infections

  2021cites this paper
• Regulatory functions of NK cells during infections and cancer

  2020cites this paper
• Blocking expression of inhibitory receptor NKG2A overcomes tumor resistance to NK cells.

  2019cites this paper
• Deciphering Effects of Uncontrolled Cytomegalovirus Replication on Immune Responses in Cytomegalovirus DNA-Positive Renal Transplant Recipients

  2019cites this paper
• Natural Killer Cell Regulation of B Cell Responses in the Context of Viral Infection

  2019influential citation
• Expression analysis of HLA-E and NKG2A and NKG2C receptors points at a role for natural killer function in ankylosing spondylitis

  2018cites this paper
• NKG2H-Expressing T Cells Negatively Regulate Immune Responses

  2018cites this paper
• HCMV triggers frequent and persistent UL40-specific unconventional HLA-E-restricted CD8 T-cell responses with potential autologous and allogeneic peptide recognition

  2018cites this paper
• NKG2A Expression Is Not per se Detrimental for the Anti-Multiple Myeloma Activity of Activated Natural Killer Cells in an In Vitro System Mimicking the Tumor Microenvironment

  2018cites this paper
• Natural killer cells from psoriasis vulgaris patients have reduced levels of cytotoxicity associated degranulation and cytokine production.

  2017cites this paper
• The effect of cytomegalovirus on natural killer cells and T cells in renal transplant recipients

  2016influential citation
• Immunobiology of HLA Class-Ib Molecules in Transplantation

  2015cites this paper
• Analyzing the effects of laquinimod on innate and adaptive immunity in mice with experimental autoimmune encephalomyelitis

  2014cites this paper
• NK cells and their ability to modulate T cells during virus infections.

  2014cites this paper
• Immunological mechanisms of tumour progression. The rationale for natural killer cell based immunotherapy for glioblastoma

  2013cites this paper
• Activating KIR2DS5 receptor is a risk for thyroid cancer.

  2012cites this paper
• Cytotoxicity of CD56bright NK Cells towards Autologous Activated CD4+ T Cells Is Mediated through NKG2D, LFA-1 and TRAIL and Dampened via CD94/NKG2A

  2012cites this paper
• KIR2DL2 Enhances Protective and Detrimental HLA Class I-Mediated Immunity in Chronic Viral Infection

  2011cites this paper