Parallel approach for solution-phase synthesis of 2-quinoxalinol analogues and their inhibition of LPS-induced TNF-alpha release on mouse macrophages in vitro.

No abstract is available for this paper.

• Publication year

  2004

• Venue

  Journal of combinatorial chemistry

• Publication date

  2004-04-07

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1021/CC034035HPMID 15132605
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Anti-TNF-α therapies: the next generation

  2003cited by this paper
• BMS-345541 Is a Highly Selective Inhibitor of IκB Kinase That Binds at an Allosteric Site of the Enzyme and Blocks NF-κB-dependent Transcription in Mice*

  2003cited by this paper
• BMS-345541 is a highly selective inhibitor of I kappa B kinase that binds at an allosteric site of the enzyme and blocks NF-kappa B-dependent transcription in mice.

  2003cited by this paper
• Anti-TNF-alpha therapies: the next generation.

  2003cited by this paper
• Induction of micronuclei in V79 cells after combined treatments with heterocyclic aromatic amines.

  2002cited by this paper
• Synthesis and antimycobacterial activity of pyrazine and quinoxaline derivatives.

  2002cited by this paper
• 2-[4-(7-chloro-2-quinoxalinyloxy)phenoxy]-propionic acid (XK469) inhibition of topoisomerase IIbeta is not sufficient for therapeutic response in human Waldenstrom's macroglobulinemia xenograft model.

  2002cited by this paper
• The Quinoxaline Derivative Caroverine in the Treatment of Sensorineural Smell Disorders: a Proof-of-Concept Study

  2002cited by this paper
• Array-based ELISAs for high-throughput analysis of human cytokines.

  2001cited by this paper
• Solid phase synthesis of 5,6,7,8-tetrahydro-1H-imidazo[4,5-g]quinoxalin-6-ones

  2000cited by this paper
• Solution-phase synthesis of a 1,5-dialkylamino-2,4-dinitrobenzene library and the identification of novel antibacterial compounds from this library.

  2000cited by this paper
• New Resin Acid Derivatives: Diisocyanate, Diurethanes and Diureides

  1998cited by this paper
• Synthesis biological evaluation of alkyl, alkoxy, alkylthio, or amino-substituted 2,3-dihydro-1,5-benzothiazepin-4(5H)-ones.

  1997cited by this paper
• Partial Reduction of Dinitroarenes to Nitroanilines with Hydrazine Hydrate

  1983cited by this paper
• An electrochemical technique for the reduction of aromatic nitro compounds

  1982cited by this paper
• Intramolecular proton exchange in aqueous histamine. An NMR method for resolving the ammonium and imidazole proton-exchange rates

  1980cited by this paper
• Homogeneous catalysts for utilization of synthesis gas as a reducing agent

  1980cited by this paper
• Titanium-Catalyzed Reduction and Rearrangement in Grignard Coupling Reaction with Silicon Halides

  1962cited by this paper
• 1,2,2-Triarylethylenes Substituted with Higher Alkyl Groups

  1957cited by this paper

• Identification of 3,5,6-substituted indolin-2-one's inhibitors of Aurora B by development of a luminescent kinase assay.

  2015cites this paper
• Amberlite IR-120H, an efficient and recyclable solid phase catalyst for the synthesis of quinoxalines: a greener approach

  2015cites this paper
• L-Proline mediated synthesis of quinoxalines; evaluation of cytotoxic and antimicrobial activity

  2014cites this paper
• Copper(II) catalyzed expeditious synthesis of furoquinoxalines through a one-pot three-component coupling strategy.

  2014cites this paper
• Present status of quinoxaline motifs: excellent pathfinders in therapeutic medicine.

  2014cites this paper
• Quinoxalin-2(1H)-one derivatives as inhibitors against hepatitis C virus.

  2011cites this paper
• The combinatorial synthesis of bioactive quinoxalines, quinoxalinones and quinoxalinols.

  2010cites this paper
• Parallel solution phase synthesis of 3,6,7-4(3H)-quinazolinones and evaluation of their antitumor activities against human cancer.

  2010cites this paper
• Multistep microwave-assisted divergent synthesis of indolo-fused pyrazino-/diazepinoquinoxalinones on PEG support.

  2010cites this paper
• Discovery and optimization of novel 3-piperazinylcoumarin antagonist of chemokine-like factor 1 with oral antiasthma activity in mice.

  2010cites this paper
• Efficient method for the synthesis of 2,3-unsubstituted nitro containing indoles from o-fluoronitrobenzenes.

  2009cites this paper
• Identification of peptide substrate and small molecule inhibitors of testis-specific serine/threonine kinase1 (TSSK1) by the developed assays.

  2009cites this paper
• 2-Quinoxalinol Salen Copper Complexes for Oxidation of Aryl Methylenes

  2009cites this paper
• Substituent diversity-directed synthesis of indole derivatives.

  2009cites this paper
• Syntheses of Novel Series Benzo [1,5] oxazepin-4-one-based Compounds from 1,5-difluoro-2,4-dinitrobenzene

  2008cites this paper
• Synthesis of diverse benzo[1,4]oxazin-3-one-based compounds using 1,5-difluoro-2,4-dinitrobenzene.

  2007cites this paper
• Solution-phase parallel synthesis of 3,5,6-substituted indolin-2-ones.

  2007cites this paper
• Design and synthesis of novel tricycles based on 4H-benzo[1,4]thiazin-3-one and 1,1-dioxo-1,4-dihydro-2H-1lambda6-benzo[1,4]thiazin-3-one.

  2007cites this paper
• Regioselective synthesis of asymmetrically substituted 2-quinoxalinol salen ligands.

  2007cites this paper
• Solution-phase parallel synthesis of diverse 1,5-benzodiazepin-2-ones.

  2007cites this paper
• An efficient method for solution-phase parallel synthesis of 2-quinoxalinol salen Schiff-base ligands.

  2007cites this paper
• Solution-phase parallel synthesis of 2,3-dihydro-1,5-benzothiazepin-4(5H)-ones.

  2007cites this paper
• Parallel solution-phase synthesis of 4H-benzo[1,4]thiazin-3-one and 1,1-dioxo-1,4-dihydro-2H-1lambda6-benzo[1,4]thiazin-3-one derivatives from 1,5-difluoro-2,4-dinitrobenzene.

  2007cites this paper
• Diverse 2-carboxamide-3-amino-substituted quinoxalines: synthesis and reactivity investigation for library generation.

  2006cites this paper
• Benzofused tricycles based on 2-quinoxalinol.

  2006cites this paper
• Solution-phase parallel synthesis of a 1,2,7-trialkyl-1H-imidazo[4,5-g]quinoxalin-6-ol library scaffold.

  2005cites this paper
• Assessment of structural diversity in combinatorial synthesis.

  2005cites this paper
• Comprehensive survey of combinatorial library synthesis: 2004.

  2005cites this paper
• Multistep parallel synthesis of substituted 5-aminobenzimidazoles in solution phase.

  2004cites this paper
• Parallel Approach for Solution-Phase Synthesis of 2-Quinoxalinol Analogues and Their Inhibition of LPS-Induced TNF-α Release on Mouse Macrophages in vitro.

  2004cites this paper