Mutation specificity of 8-methoxypsoralen plus two doses of UVA irradiation in the hprt gene in diploid human fibroblasts.

No abstract is available for this paper.

• Publication year

  1994

• Venue

  Carcinogenesis

• Publication date

  1994-02-01

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1093/CARCIN/15.2.201PMID 8313509
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Molecular spectrum of mutations induced at the HPRT locus by a cross-linking agent in human cell lines with different repair capacities.

  1993cited by this paper
• Molecular mechanism of transcription-repair coupling.

  1993cited by this paper
• Mutagenicity and mutational spectrum of N-methyl-N'-nitro-N-nitrosoguanidine in the hprt gene in G1-S and late S phase of diploid human fibroblasts.

  1993cited by this paper
• The skipping of constitutive exons in vivo induced by nonsense mutations

  1993cited by this paper
• DNA repair. Engagement with transcription.

  1993cited by this paper
• 8‐Methoxypsoralen induced mutations are highly targeted at crosslinkable sites of photoaddition on the non‐transcribed strand of a mammalian chromosomal gene.

  1993cited by this paper
• DNA repair by eukaryotic nucleotide excision nuclease. Removal of thymine dimer and psoralen monoadduct by HeLa cell-free extract and of thymine dimer by Xenopus laevis oocytes.

  1993cited by this paper
• Mutagenic processing of psoralen monoadducts differ in normal and Fanconi anemia cells.

  1993cited by this paper
• The evolution of photochemotherapy with psoralens and UVA (PUVA): 2000 BC to 1992 AD.

  1992cited by this paper
• Mutations which alter splicing in the human hypoxanthine-guanine phosphoribosyltransferase gene.

  1992cited by this paper
• Preferential repair and strand-specific repair of benzo[a]pyrene diol epoxide adducts in the HPRT gene of diploid human fibroblasts.

  1992cited by this paper
• Structure of the DNA interstrand cross-link of 4,5',8-trimethylpsoralen.

  1992cited by this paper
• Molecular analysis of mutations induced by 4'-hydroxymethyl-4,5',8-trimethylpsoralen and UVA in the mouse HPRT gene.

  1992cited by this paper
• ERCC6, a member of a subfamily of putative helicases, is involved in Cockayne's syndrome and preferential repair of active genes.

  1992cited by this paper
• Human nucleotide excision nuclease removes thymine dimers from DNA by incising the 22nd phosphodiester bond 5' and the 6th phosphodiester bond 3' to the photodimer.

  1992cited by this paper
• Human HPRT mutant database: Software for data entry and retrieval

  1992cited by this paper
• DNA replication fidelity.

  1992cited by this paper
• Autoregulation and multifunctionality among trans-acting factors that regulate alternative pre-mRNA processing.

  1992cited by this paper
• Heterogeneity of DNA repair at the gene level.

  1991cited by this paper
• Differential introduction and repair of psoralen photoadducts to DNA in specific human genes.

  1991cited by this paper
• RecA-dependent incision of psoralen-crosslinked DNA by (A)BC excinuclease.

  1991cited by this paper
• Strand specificity for UV-induced DNA repair and mutations in the Chinese hamster HPRT gene.

  1991cited by this paper
• Photoprotection and 5-MOP photochemoprotection from UVR-induced DNA damage in humans: the role of skin type.

  1991cited by this paper
• Gene- and strand-specific repair in vitro: partial purification of a transcription-repair coupling factor.

  1991cited by this paper
• Photopheresis: present and future aspects.

  1991cited by this paper
• Mechanisms of alternative pre-mRNA splicing.

  1991cited by this paper
• Novel mutational spectrum induced by N-methyl-N'-nitro-N-nitrosoguanidine in the coding region of the hypoxanthine (guanine) phosphoribosyltransferase gene in diploid human fibroblasts.

  1991cited by this paper
• Misalignment-mediated DNA synthesis errors.

  1990cited by this paper
• Genital tumors among men with psoriasis exposed to psoralens and ultraviolet A radiation (PUVA) and ultraviolet B radiation. The Photochemotherapy Follow-up Study.

  1990cited by this paper
• Multiplex DNA deletion detection and exon sequencing of the hypoxanthine phosphoribosyltransferase gene in Lesch-Nyhan families.

  1990cited by this paper
• DNA base composition determines the specificity of UvrABC endonuclease incision of a psoralen cross-link.

  1990cited by this paper
• Automated DNA sequencing of the human HPRT locus.

  1990cited by this paper
• RECENT ADVANCES IN PSORALEN PHOTOTOXICITY MECHANISM

  1989cited by this paper
• DNA strand specificity for UV-induced mutations in mammalian cells

  1989cited by this paper
• Nonsense mutations in the dihydrofolate reductase gene affect RNA processing

  1989cited by this paper
• Amplification and direct nucleotide sequencing of cDNA from the lysate of low numbers of diploid human cells.

  1989cited by this paper
• DNA sequence specificity of 4,5',8-trimethylpsoralen cross-linking. Effect of neighboring bases on cross-linking the 5'-TA dinucleotide.

  1988cited by this paper
• Mutagenesis induced by site specifically placed 4'-hydroxymethyl-4,5',8-trimethylpsoralen adducts.

  1988cited by this paper
• Photoreactivities and thermal properties of psoralen cross-links.

  1988cited by this paper
• Sequence context effects on 8-methoxypsoralen photobinding to defined DNA fragments.

  1987cited by this paper
• Suppressible base substitution mutations induced by angelicin (isopsoralen) in the Escherichia coli lacI gene: implications for the mechanism of SOS mutagenesis

  1987cited by this paper
• A nonsense mutation causes hereditary goitre in the Afrikander cattle and unmasks alternative splicing of thyroglobulin transcripts.

  1987cited by this paper
• The repair of psoralen monoadducts by the Escherichia coli UvrABC endonuclease.

  1987cited by this paper
• Processing of psoralen adducts in an active human gene: repair and replication of DNA containing monoadducts and interstrand cross-links.

  1987cited by this paper
• Mutagenesis by 8-methoxypsoralen plus near-UV treatment: analysis of specificity in the lacI gene of Escherichia coli.

  1986cited by this paper
• Sodium arsenite potentiates the clastogenicity and mutagenicity of DNA crosslinking agents.

  1986cited by this paper
• Psoralens as photoactive probes of nucleic acid structure and function: organic chemistry, photochemistry, and biochemistry.

  1985cited by this paper
• Mutagenesis of the lac promoter region in M13 mp10 phage DNA by 4'-hydroxymethyl-4,5',8-trimethylpsoralen.

  1985cited by this paper
• Photochemistry of the furan-side 8-methoxypsoralen-thymidine monoadduct inside the DNA helix. Conversion to diadduct and to pyrone-side monoadduct.

  1985cited by this paper
• Organization of the HPRT gene and related sequences in the human genome

  1984cited by this paper
• EFFICIENT FORMATION OF A CROSSLINKABLE HMT MONOADDUCT AT THE Kpn I RECOGNITION SITE

  1984cited by this paper
• Cutaneous squamous-cell carcinoma in patients treated with PUVA.

  1984cited by this paper
• Induction of SCE by DNA cross-links in human fibroblasts exposed to 8-MOP and UVA irradiation.

  1983cited by this paper
• On the types of chromosomal aberrations induced by 8-methoxypsoralen.

  1983cited by this paper
• Psoralen-deoxyribonucleic acid photoreaction. Characterization of the monoaddition products from 8-methoxypsoralen and 4,5'8-trimethylpsoralen.

  1982cited by this paper

• In Regard to Yoon et al.

  2018cites this paper
• Characterising In-111-anti-γH2AX-TAT in targeting the DNA damage signal associated with Wnt activated colorectal cancer

  2016cites this paper
• Mechanisms underlying mutational signatures in human cancers

  2014cites this paper
• METHOXSALEN PLUS ULTRAVIOLET A RADIATION

  2012cites this paper
• Bypass of a psoralen DNA interstrand cross-link by DNA polymerases β, ι, and κ in vitro.

  2012cites this paper
• iArc monogrAphs on the evAluAtion oF cArcinogenic risks to humAns

  2012cites this paper
• Exposure Data 1 . 1 Identification of the agent

  2012cites this paper
• DNA interstrand crosslink repair in mammalian cells: step by step

  2010cites this paper
• Triplex targeted genomic crosslinks enter separable deletion and base substitution pathways

  2005cites this paper
• Biological consequences of 8-methoxypsoralen-photoinduced lesions: sequence-specificity of mutations and preponderance of T to C and T to a mutations.

  2004cites this paper
• The ultraviolet fingerprint dominates the mutational spectrum of the p53 and Ha-ras genes in psoralen + ultraviolet A keratoses from psoriasis patients.

  2004cites this paper
• High frequency of ultraviolet mutations at the INK4a-ARF locus in squamous cell carcinomas from psoralen-plus-ultraviolet-A-treated psoriasis patients.

  2003cites this paper
• Reproductive toxicity of the psoralens.

  2003cites this paper
• Effects of the isoflavone 4',5,7-trihydroxyisoflavone (genistein) on psoralen plus ultraviolet A radiation (PUVA)-induced photodamage.

  2002cites this paper
• High Mutation Frequency at Ha‐ras Exons 1–4 in Squamous Cell Carcinomas from PUVA‐treated Psoriasis Patients ¶

  2001cites this paper
• The psoralens adversely affect reproductive function in male wistar rats.

  2001cites this paper
• Repair of DNA interstrand cross-links.

  2001cites this paper
• High Mutation Frequency at Ha-ras Exons 1–4 in Squamous Cell Carcinomas from PUVA-treated Psoriasis Patients¶

  2001cites this paper
• Predicted changes in pre-mRNA secondary structure vary in their association with exon skipping for mutations in exons 2, 4, and 8 of the Hprt gene and exon 51 of the fibrillin gene.

  2000cites this paper
• The Role of PUVA in the Treatment of Psoriasis

  2000cites this paper
• p53 mutations experimentally induced by 8-methoxypsoralen plus UVA (PUVA) differ from those found in human skin cancers in PUVA-treated patients.

  2000influential citation
• 7.5 – 8-Methoxypsoralen Compromises the Development of Ovarian Large Antral Follicles in Wistar Rats

  2000cites this paper
• Examination of psoralens-induced photodermatitis in Wistar rats under scanning electron microscopy.

  1999cites this paper
• Psoralen photochemotherapy, clinical efficacy, and photomutagenicity: The role of molecular epidemiology in minimizing risks

  1998cites this paper
• Mutations that alter RNA splicing of the human HPRT gene: a review of the spectrum.

  1998cites this paper
• Transcription coupled repair and its impact on mutagenesis.

  1998cites this paper
• Dynamics in psoralen-damaged DNA by 1H-detected natural abundance 13C NMR spectroscopy.

  1998cites this paper
• p53 mutation in squamous cell carcinomas from psoriasis patients treated with psoralen + UVA (PUVA).

  1997cites this paper
• Toxicity and repair of psoralen adducts in bacteriophage T7.

  1997cites this paper
• Spectra of X-ray-induced and spontaneous intragenic HPRT mutations in closely related human cells differentially expressing the p53 tumor suppressor gene.

  1997cites this paper
• Signature p53 mutation at DNA cross-linking sites in 8-methoxypsoralen and ultraviolet A (PUVA)-induced murine skin cancers.

  1996cites this paper
• The mutagenic processing of psoralen photolesions leaves a highly specific signature at an endogenous human locus.

  1996cites this paper
• Mutagenic and carcinogenic properties of platinum-based anticancer drugs.

  1996cites this paper
• Strand specificity of mutagenic bypass replication of DNA containing psoralen monoadducts in a human cell extract

  1996cites this paper
• Genomic DNA sequencing of mRNA splicing mutants in the hprt gene of chinese hamster ovary cells

  1995cites this paper
• Mutagenesis by 8-methoxypsoralen and 5-methylangelicin photoadducts in mouse fibroblasts: mutations at cross-linkable sites induced by offoadducts as well as cross-links.

  1995influential citation
• Genotoxic potential of psoralen cross-links versus monoadducts in normal human lymphoblasts.

  1995cites this paper
• DNA sequence analysis of HPRT- mutants induced in human lymphoblastoid cells adapted to ionizing radiation.

  1995cites this paper
• Interaction of cultured rat osteoblasts with 8-methoxypsoralen during irradiation with long-wave ultraviolet light.

  1995cites this paper
• Solution structures of psoralen monoadducted and cross-linked DNA oligomers by NMR spectroscopy and restrained molecular dynamics.

  1995cites this paper
• Mutagenicity and specific mutation spectrum induced by 8-methoxypsoralen plus a low dose of UVA in the hprt gene in diploid human fibroblasts.

  1995cites this paper
• Transcription-coupled repair of psoralen cross-links but not monoadducts in Chinese hamster ovary cells.

  1994cites this paper