S-nitrosoglutathione reduces tau hyper-phosphorylation and provides neuroprotection in rat model of chronic cerebral hypoperfusion.

No abstract is available for this paper.

• Publication year

  2015

• Venue

  Brain Research

• Publication date

  2015-10-22

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1016/j.brainres.2015.07.057PMID 26271717PMCID PMC4630117
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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• Embryonic transplantation and ischemic memory deficit.

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